- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-06-21 15:17:22+12:00
- Desc:
- Add comments for paramater difference from difference sources in default_values.cellml
Add T and Cao in the patch experiment to simulate fig 11;
Add T in the periodic stimulation experiment; Add fig 10 and 11;
Rerun the simulation and update the documentation.
- Permanent Source URI:
- https://models.cellml.org/workspace/692/rawfile/83d7d73639ae18c0fea6c0befe2b40552ab06de6/Experiments/Patch_clamp_protocol.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="Patch_clamp_protocol" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
<!-- clamp the voltage for the activation behaviour-->
<import xlink:href="../Components/units.cellml">
<units name="ms" units_ref="ms"/>
<units name="mV" units_ref="mV"/>
</import>
<component name="Patch_clamp_protocol">
<variable name="V" public_interface="out" units="mV"/>
<variable name="time" public_interface="in" units="ms"/>
<variable cmeta:id="steady_state_time" name="t_ss" public_interface="in" units="ms"/>
<variable cmeta:id="activation_holding_potential" name="V_actHolding" public_interface="in" units="mV"/>
<variable cmeta:id="activation_test_potential" name="V_actTest" public_interface="in" units="mV"/>
<!--get the model to steady state at the holding potential.-->
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="activation_protocol_clamping">
<eq/>
<ci>V</ci>
<piecewise>
<piece>
<ci>V_actHolding</ci>
<apply>
<lt/>
<ci>time</ci>
<ci>t_ss</ci>
</apply>
</piece>
<otherwise>
<ci>V_actTest</ci>
</otherwise>
</piecewise>
</apply>
</math>
</component>
</model>