- Author:
- WeiweiAi <wai484@aucklanduni.ac.nz>
- Date:
- 2021-06-02 14:40:15+12:00
- Desc:
- Add E_Nernst to instantiate Nernst potential for Ca, Na and K and modify relevant models to accommodate the change.
Add experiment of Periodic_stimulation, which can run.
- Permanent Source URI:
- https://models.cellml.org/workspace/692/rawfile/d5a44a9d949275dfd1b2e46aeaa827571356cd68/Components/INS_K.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="INS_K" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units.cellml">
<units name="mM" units_ref="mM"/>
<units name="pA" units_ref="pA"/>
<units name="mV" units_ref="mV"/>
<units name="nS" units_ref="nS"/>
<units name="J_per_K_mol" units_ref="J_per_K_mol"/>
<units name="C_per_mmol" units_ref="C_per_mmol"/>
</import>
<import xlink:href="Ionic_currents.cellml">
<component component_ref="Ionic_currents" name="Ionic_currents"/>
</import>
<import xlink:href="E_Nernst.cellml">
<component component_ref="E_K" name="E_K"/>
</import>
<component name="INS_K">
<variable name="I_NsK" private_interface="in" public_interface="out" units="pA"/>
<variable name="V" private_interface="out" public_interface="in" units="mV"/>
<variable name="g_NsK" private_interface="out" public_interface="in" units="nS"/>
<variable name="T" private_interface="out" public_interface="in" units="kelvin"/>
<variable name="Ko" private_interface="out" public_interface="in" units="mM"/>
<variable name="Ki" private_interface="out" public_interface="in" units="mM"/>
<variable initial_value="1" name="PO" private_interface="out" units="dimensionless"/>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="INS_K">
<component_ref component="Ionic_currents"/>
<component_ref component="E_K"/>
</component_ref>
</group>
<connection>
<map_components component_1="INS_K" component_2="Ionic_currents"/>
<map_variables variable_1="I_NsK" variable_2="I"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="g_NsK" variable_2="g_max"/>
<map_variables variable_1="PO" variable_2="PO"/>
</connection>
<connection>
<map_components component_1="INS_K" component_2="E_K"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="Ki" variable_2="Ki"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
</connection>
<connection>
<map_components component_1="E_K" component_2="Ionic_currents"/>
<map_variables variable_1="E_K" variable_2="E"/>
</connection>
</model>