- Author:
- leyla <noroozbabaee@gmail.com>
- Date:
- 2021-06-28 20:13:23+12:00
- Desc:
- Conversion of the Epithelial Modules From Python to CellML
- Permanent Source URI:
- https://models.cellml.org/workspace/6b4/rawfile/74195ac8689f1c97c4ebffbce80647281475f5a6/Na_H2PO4_Weinstein/components/Na_H2PO4.cellml
<?xml version='1.0'?>
<model cmeta:id="Na_H2PO4_model" name="Na_H2PO4_model" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
<!-- ============================================= Import the required units from the Units file ==================================================== -->
<import xlink:href="../general/Units_for_EpithelialCell.cellml">
<units name="millivolt" units_ref="millivolt"/>
<units name="per_second" units_ref="per_second"/>
<units name="coulomb_per_mole" units_ref="coulomb_per_mole"/>
<units name="joule_per_millimole" units_ref="joule_per_millimole"/>
<units name="molar" units_ref="molar"/>
<units name="millimole2_per_joulesecond" units_ref="millimole2_per_joulesecond"/>
<units name="millimole_per_second" units_ref="millimole_per_second"/>
<units name="joule_per_coulombmillivolt" units_ref="joule_per_coulombmillivolt"/>
</import>
<!--=================================== INPUT CONNECTIONS ============================= -->
<import xlink:href="../general/Generator.cellml">
<component component_ref="experiment" name="experiment"/>
</import>
<!-- ======================================== SGLT1 TOP-LEVEL COMPONENT ============================================= -->
<connection>
<map_components component_1="experiment" component_2="Weinstein_NaH2PO4"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Na_I" variable_2="Na_I"/>
<map_variables variable_1="H2PO4_I" variable_2="H2PO4_I"/>
<map_variables variable_1="Vm" variable_2="Vm"/>
<map_variables variable_1="Vi" variable_2="Vi"/>
</connection>
<!-- ======================================== Weinstein_SGLT_TRANSPORTER ============================================= -->
<component cmeta:id="Weinstein_NaH2PO4" name="Weinstein_NaH2PO4">
<!-- Inputs from other components -->
<variable name="time" private_interface="out" public_interface="in" units="second"/>
<variable name="Na_I" private_interface="in" public_interface="out" units="molar"/>
<variable name="H2PO4_I" private_interface="in" public_interface="out" units="molar"/>
<variable name="Vm" private_interface="in" public_interface="out" units="millivolt"/>
<variable name="Vi" private_interface="in" public_interface="out" units="millivolt"/>
<!-- Outputs to other components -->
<variable name="Na_NaH2PO4_Flux" private_interface="out" public_interface="out" units="millimole_per_second"/>
<variable name="H2PO4_NaH2PO4_Flux" private_interface="out" public_interface="out" units="millimole_per_second"/>
<!-- Parameters from parameter_file -->
<variable name="F" private_interface="none" public_interface="in" units="coulomb_per_mole"/>
<variable name="Na_M" private_interface="out" public_interface="in" units="molar"/>
<variable name="H2PO4_M" private_interface="out" public_interface="in" units="molar"/>
<variable name="zna" private_interface="none" public_interface="in" units="dimensionless"/>
<variable name="zh2po4" private_interface="none" public_interface="in" units="dimensionless"/>
<variable name="L_nah2po4" private_interface="none" public_interface="in" units="millimole2_per_joulesecond"/>
<variable name="Ami" private_interface="out" public_interface="in" units="dimensionless"/>
<variable name="rte" private_interface="none" public_interface="in" units="joule_per_millimole"/>
<variable initial_value="0.0" name="m" public_interface="out" units="second"/>
<!-- Internal variables -->
<variable name="mu_Na_M" private_interface="out" public_interface="out" units="joule_per_millimole"/>
<variable name="mu_H2PO4_M" private_interface="out" public_interface="out" units="joule_per_millimole"/>
<variable name="mu_Na_I" private_interface="out" public_interface="out" units="joule_per_millimole"/>
<variable name="mu_H2PO4_I" private_interface="out" public_interface="out" units="joule_per_millimole"/>
<variable name="delta_mu_Na" private_interface="out" public_interface="out" units="joule_per_millimole"/>
<variable name="delta_mu_H2PO4" private_interface="out" public_interface="out" units="joule_per_millimole"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>mu_Na_M</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>rte</ci>
<apply>
<ln/>
<ci>Na_M</ci>
</apply>
</apply>
<apply>
<times/>
<ci>zna</ci>
<ci>F</ci>
<ci>Vm</ci>
<cn cellml:units="joule_per_coulombmillivolt">1</cn>
<apply>
<power/>
<cn cellml:units="dimensionless">10.0</cn>
<apply>
<minus/>
<cn cellml:units="dimensionless">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_Na_I</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>rte</ci>
<apply>
<ln/>
<ci>Na_I</ci>
</apply>
</apply>
<apply>
<times/>
<ci>zna</ci>
<ci>F</ci>
<ci>Vi</ci>
<cn cellml:units="joule_per_coulombmillivolt">1</cn>
<apply>
<power/>
<cn cellml:units="dimensionless">10.0</cn>
<apply>
<minus/>
<cn cellml:units="dimensionless">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_H2PO4_M</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>rte</ci>
<apply>
<ln/>
<ci>H2PO4_M</ci>
</apply>
</apply>
<apply>
<times/>
<ci>zh2po4</ci>
<ci>F</ci>
<ci>Vm</ci>
<cn cellml:units="joule_per_coulombmillivolt">1</cn>
<apply>
<power/>
<cn cellml:units="dimensionless">10.0</cn>
<apply>
<minus/>
<cn cellml:units="dimensionless">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>mu_H2PO4_I</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>rte</ci>
<apply>
<ln/>
<ci>H2PO4_I</ci>
</apply>
</apply>
<apply>
<times/>
<ci>zh2po4</ci>
<ci>F</ci>
<ci>Vi</ci>
<cn cellml:units="joule_per_coulombmillivolt">1</cn>
<apply>
<power/>
<cn cellml:units="dimensionless">10.0</cn>
<apply>
<minus/>
<cn cellml:units="dimensionless">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>delta_mu_Na</ci>
<apply>
<minus/>
<ci>mu_Na_M</ci>
<ci>mu_Na_I</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>delta_mu_H2PO4</ci>
<apply>
<minus/>
<ci>mu_H2PO4_M</ci>
<ci>mu_H2PO4_I</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Na_NaH2PO4_Flux</ci>
<apply>
<times/>
<ci>L_nah2po4</ci>
<ci>Ami</ci>
<apply>
<plus/>
<ci>delta_mu_Na</ci>
<ci>delta_mu_H2PO4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>H2PO4_NaH2PO4_Flux</ci>
<apply>
<times/>
<ci>L_nah2po4</ci>
<ci>Ami</ci>
<apply>
<plus/>
<ci>delta_mu_Na</ci>
<ci>delta_mu_H2PO4</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>m</ci>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="Weinstein_NaH2PO4">
<component_ref component="experiment"/>
</component_ref>
</group>
</model>
