Location: cellLib @ 537e3bc704f3 / Protocols / periodic-IStim-protocol.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2021-11-15 15:36:35+13:00
Desc:
Modify the option and layout of plots
Permanent Source URI:
https://models.cellml.org/workspace/6bc/rawfile/537e3bc704f362367cc841be142b6b7eaa6da9c6/Protocols/periodic-IStim-protocol.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="periodic_IStim" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../Components/units.cellml">
        <units name="ms" units_ref="ms"/>
        <units name="pA_per_pF" units_ref="pA_per_pF"/>
        <units name="uA_per_cmsq" units_ref="uA_per_cmsq"/>
    </import>
    <component name="stimulus_protocol">
        <variable name="time" public_interface="in" units="ms"/>
        <variable name="stimPeriod" public_interface="in" units="ms"/>
        <variable name="stimDuration" public_interface="in" units="ms"/>
        <variable name="stimCurrent" public_interface="in" units="uA_per_cmsq"/>
        <variable name="IStim" public_interface="out" units="uA_per_cmsq"/>
        <variable cmeta:id="localTimer" name="t" units="ms"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>t</ci>
                <apply>
                    <minus/>
                    <ci>time</ci>
                    <apply>
                        <times/>
                        <ci>stimPeriod</ci>
                        <apply>
                            <floor/>
                            <apply>
                                <divide/>
                                <ci>time</ci>
                                <ci>stimPeriod</ci>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply id="stimulus_calculation">
                <eq/>
                <ci>IStim</ci>
                <piecewise>
                    <piece>
                        <ci>stimCurrent</ci>
                        <apply>
                            <lt/>
                            <ci>t</ci>
                            <ci>stimDuration</ci>
                        </apply>
                    </piece>
                    <otherwise>
                        <cn cellml:units="uA_per_cmsq">0.0</cn>
                    </otherwise>
                </piecewise>
            </apply>
        </math>
    </component>
    <component name="sPulse_protocol_ms">
        <variable name="time" public_interface="in" units="ms"/>
        <variable cmeta:id="hold_time" name="t_ss" public_interface="in" units="ms"/>
        <variable cmeta:id="holding_current" name="I_holding" public_interface="in" units="pA_per_pF"/>
        <variable cmeta:id="activation_duration" name="t_act" public_interface="in" units="ms"/>
        <variable cmeta:id="activation_current" name="I_actTest" public_interface="in" units="pA_per_pF"/>
        <variable name="I_stim" public_interface="out" units="pA_per_pF"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply id="stimulus">
                <eq/>
                <ci>I_stim</ci>
                <piecewise>
                    <piece>
                        <ci>I_holding</ci>
                        <apply>
                            <lt/>
                            <ci>time</ci>
                            <ci>t_ss</ci>
                        </apply>
                    </piece>
                    <piece>
                        <ci>I_actTest</ci>
                        <apply>
                            <and/>
                            <apply>
                                <geq/>
                                <ci>time</ci>
                                <ci>t_ss</ci>
                            </apply>
                            <apply>
                                <lt/>
                                <ci>time</ci>
                                <apply>
                                    <plus/>
                                    <ci>t_act</ci>
                                    <ci>t_ss</ci>
                                </apply>
                            </apply>
                        </apply>
                    </piece>
                    <otherwise>
                        <ci>I_holding</ci>
                    </otherwise>
                </piecewise>
            </apply>
        </math>
    </component>
    <component name="mPulse_protocol_ms">
        <variable name="time" public_interface="in" units="ms"/>
        <variable cmeta:id="hold_time" name="t_ss" public_interface="in" units="ms"/>
        <variable cmeta:id="holding_current" name="I_holding" public_interface="in" units="pA_per_pF"/>
        <variable cmeta:id="activation_duration" name="t_act" public_interface="in" units="ms"/>
        <variable cmeta:id="activation_current" name="I_actTest" public_interface="in" units="pA_per_pF"/>
        <variable cmeta:id="interpulse" name="t_intp" public_interface="in" units="ms"/>
        <variable cmeta:id="period" name="stimPeriod" units="ms"/>
        <variable cmeta:id="localTimer" name="t" units="ms"/>
        <variable cmeta:id="pulse_number" name="np" public_interface="in" units="dimensionless"/>
        <variable name="I_stim" public_interface="out" units="pA_per_pF"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>stimPeriod</ci>
                <apply>
                    <plus/>
                    <ci>t_act</ci>
                    <ci>t_intp</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>t</ci>
                <apply>
                    <minus/>
                    <apply>
                        <minus/>
                        <ci>time</ci>
                        <ci>t_ss</ci>
                    </apply>
                    <apply>
                        <times/>
                        <ci>stimPeriod</ci>
                        <apply>
                            <floor/>
                            <apply>
                                <divide/>
                                <apply>
                                    <minus/>
                                    <ci>time</ci>
                                    <ci>t_ss</ci>
                                </apply>
                                <ci>stimPeriod</ci>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply id="stimuli">
                <eq/>
                <ci>I_stim</ci>
                <piecewise>
                    <piece>
                        <ci>I_holding</ci>
                        <apply>
                            <lt/>
                            <ci>time</ci>
                            <ci>t_ss</ci>
                        </apply>
                    </piece>
                    <piece>
                        <ci>I_actTest</ci>
                        <apply>
                            <and/>
                            <apply>
                                <geq/>
                                <ci>time</ci>
                                <ci>t_ss</ci>
                            </apply>
                            <apply>
                                <leq/>
                                <ci>t</ci>
                                <ci>t_act</ci>
                            </apply>
                            <apply>
                                <leq/>
                                <ci>time</ci>
                                <apply>
                                    <plus/>
                                    <ci>t_ss</ci>
                                    <apply>
                                        <times/>
                                        <ci>stimPeriod</ci>
                                        <ci>np</ci>
                                    </apply>
                                </apply>
                            </apply>
                        </apply>
                    </piece>
                    <otherwise>
                        <ci>I_holding</ci>
                    </otherwise>
                </piecewise>
            </apply>
        </math>
    </component>
</model>