- Author:
- nima <nafs080@aucklanduni.ac.nz>
- Date:
- 2021-10-13 16:47:27+13:00
- Desc:
- Updated Documentation
- Permanent Source URI:
- https://models.cellml.org/workspace/702/rawfile/bfef836a3a4a1e8b02e5da6e11eb9a8f74ab99a4/Components.rst
About this model
====================
:Original publication: `Kernik et al. (2019)`_:
"A computational model of induced pluripotent stem-cell derived cardiomyocytes \
incorporating experimental variability from multiple data sources" J Physiol. 2019 Sep 1; 597(17): 4533-4564.
:DOI: https://dx.doi.org/10.1113%2FJP277724
.. _`Kernik et al. (2019)`: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6767694/
************
CellML files
************
This folder contains all the required CellML codes,
CellML can build a model in a modular way which divides the model
into distinct modules, which can be re-used.
The main CellML files:
- `Channels <Channels>`_ which include:
- Probability of channels gates being open or close: `act_inact <Channels/act_inact.cellml>`_
this file is the main CellML file which is the top model in the hierarchical modular
presentation and rest of the files need to be imported here in order to run the simulation.
- Hodgkin-Huxley-type gating formulations are provided in a single module here: `gatting <Channels/gatting.cellml>`_
- General file for required parameters: `parameter <Channels/parameter.cellml>`_
This file is a general file, specific parameters for each channel are
presented in associated python script.
- All the required units for this simulation: `unit <Channels/unit.cellml>`_
.. _`act_inact.cellml`: https://models.physiomeproject.org/e/768/Channels/act_inact.cellml/view/
.. _`gating.cellml`: https://models.physiomeproject.org/e/768/Channels/gating.cellml/view/
.. _`parameter.cellml`: https://models.physiomeproject.org/e/768/Channels/parameter.cellml/view/
.. _`unit.cellml`: https://models.physiomeproject.org/e/768/Channels/unit.cellml/view/
