Location: Calcium Dynamics Annotations @ 4d6408caaf3e / jafri_rice_winslow_1998_a / model / jafri_rice_winslow_1998_a.rdf

Author:

neilstephen2001 <npar276@aucklanduni.ac.nz>

Date:

2021-01-26 14:35:03+13:00

Desc:

modifying rdf files

Permanent Source URI:

https://models.cellml.org/workspace/7f1/rawfile/4d6408caaf3e7b1b86d33d53d26105360ef95347/jafri_rice_winslow_1998_a/model/jafri_rice_winslow_1998_a.rdf

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bqmodel="http://biomodels.net/model-qualifiers/"
    xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.Nao">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_2">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_3">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:70022"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.J_up">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
    <dcterms:description>calcium uptake flux by SERCA pumps</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.eta">
    <dcterms:description>voltage dependence of sodium-calcium exchange</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.i_NaCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.g_K_max">
    <dcterms:description>maximum time-dependent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.RyR_open">
    <dcterms:description>fraction of open ryanodine receptor channels</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.Ko">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_7">
        <bqbiol:isPartOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_3"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_background_current.E_NaN">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C_Ca1">
    <dcterms:description>L-type calcium channel closed state mode calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.Ko">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.i_Ca_L_Ca_half">
    <dcterms:description>L-type calcium current level that reduces potassium permeability by half</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.Cm">
    <dcterms:description>membrane capacitance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.V_JSR">
    <dcterms:description>junctional sarcoplasmic reticulum volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_ns_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific calcium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_htrpn_minus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>calcium off rate constant for troponin high-affinity sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-dependent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current_j_gate.beta_j">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.HTRPN_tot">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_14">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_1">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:226050"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62338"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>total concentration of myoplasmic high-affinity troponin binding sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.Nao">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.i_p_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sarcolemmal calcium pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.g_">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>transition rate out of open state</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.O">
    <dcterms:description>L-type calcium channel conducting state mode normal</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.i_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-dependent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C_Ca2">
    <dcterms:description>L-type calcium channel closed state mode calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_background_current.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_background_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.Ko">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.i_Ca_L_Ca_max">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>maximum L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current_K1_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_Ca_L_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>potassium-activated L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.nCa">
    <dcterms:description>ryanodine receptor calcium cooperativity parameter PC1 - PO1</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.i_ns_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific potassium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.K_mCSQN">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_10">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_11">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62387"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for calsequestrin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.Ki">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_8">
        <bqbiol:isPartOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_1"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.Kp">
    <dcterms:description>steady state plateau potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.E_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>time-independent potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.V_SS">
    <dcterms:description>subspace sarcoplasmic reticulum volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel_y_gate.tau_y">
    <dcterms:description>time constant for L-type calcium channel inactivation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_ns_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific sodium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_Kp">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>plateau potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C4">
    <dcterms:description>L-type calcium channel closed state mode normal</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.i_Ca_L_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium-activated L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.Ca_NSR">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_12">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_13">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62390"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in network sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel_i_Ca_L_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium-activated L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_X_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.mCa">
    <dcterms:description>ryanodine receptor calcium cooperativity parameter PO1 - PO2</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.Am">
    <dcterms:description>capacitive membrane area</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current_h_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current_K1_gate.E_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>time-independent potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.g_K1">
    <dcterms:description>time-independent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.K_mup">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_9">
        <bqbiol:isPartOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_1"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>half-saturation constant for SERCA pumps</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.Bi">
    <dcterms:description>rate of change in free calcium concentration in the myoplasm</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.VnsCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>non-specific calcium-activated current equilibrium potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current_m_gate.m">
    <dcterms:description>fast sodium current channel activation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_Ca_b">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.I_NaK">
    <dcterms:description>maximum sodium-potassium pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
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    <dcterms:description>L-type calcium channel closed state mode calcium</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
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    <dcterms:description>maximum sodium channel conductance</dcterms:description>
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    <dcterms:description>sodium permeability of potassium channel</dcterms:description>
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    <dcterms:description>sodium-calcium exchange saturation factor at very negative potentials</dcterms:description>
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    <dcterms:description>fast sodium current channel slow inactivation gate</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
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    <dcterms:description>maximum sarcolemmal calcium pump current</dcterms:description>
  </rdf:Description>
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    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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    <dcterms:description>fraction of channels in state PC1</dcterms:description>
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    <dcterms:description>fast sodium current channel inactivation gate</dcterms:description>
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    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#jafri_1998"
     semsim:unknown="Mammalia@en"
     bqmodel:isDescribedBy="9512016"
     semsim:modelName="jafri_1998">
    <semsim:unknown>The Jafri-Rice-Winslow Model for Calcium Regulation in the Ventricular
        Myocyte, 1997@en</semsim:unknown>
    <semsim:hasCellMLdocumentation>&lt;documentation xmlns="http://cellml.org/tmp-documentation"&gt;&#xD;
  &lt;article&gt;&#xD;
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      &lt;title&gt;Jafri-Rice-Winslow Ventricular Model 1998&lt;/title&gt;&#xD;
      &lt;author&gt;&#xD;
        &lt;firstname&gt;Noble&lt;/firstname&gt;&#xD;
        &lt;surname&gt;Penny&lt;/surname&gt;&#xD;
        &lt;affiliation&gt;&#xD;
          &lt;shortaffil&gt;Cardiac Electrophysiology Group, Oxford University&lt;/shortaffil&gt;&#xD;
        &lt;/affiliation&gt;&#xD;
      &lt;/author&gt;&#xD;
    &lt;/articleinfo&gt;&#xD;
    &lt;section id="sec_status"&gt;&#xD;
      &lt;title&gt;Model Status&lt;/title&gt;&#xD;
      &lt;para&gt;This model is known to run in both OpenCell and COR, and has been curated by Penny Noble of Oxford University. The units have been checked and they are consistent.&lt;/para&gt;&#xD;
    &lt;/section&gt;&#xD;
    &lt;sect1 id="sec_structure"&gt;&#xD;
      &lt;title&gt;Model Structure&lt;/title&gt;&#xD;
      &lt;para&gt;ABSTRACT: We construct a detailed mathematical model for Ca2+ regulation in the ventricular myocyte that includes novel descriptions of subcellular mechanisms based on recent experimental findings: 1) the Keizer-Levine model for the ryanodine receptor (RyR), which displays adaptation at elevated Ca2+; 2) a model for the L-type Ca2+ channel that inactivates by mode switching; and 3) a restricted subspace into which the RyRs and L-type Ca2+ channels empty and interact via Ca2+. We add membrane currents from the Luo-Rudy Phase II ventricular cell model to our description of Ca2+ handling to formulate a new model for ventricular action potentials and Ca2+ regulation. The model can simulate Ca2+ transients during an action potential similar to those seen experimentally. The subspace [Ca2+] rises more rapidly and reaches a higher level (10-30 microM) than the bulk myoplasmic Ca2+ (peak [Ca2+]i approximately 1 microM). Termination of sarcoplasmic reticulum (SR) Ca2+ release is predominately due to emptying of the SR, but is influenced by RyR adaptation. Because force generation is roughly proportional to peak myoplasmic Ca2+, we use [Ca2+]i in the model to explore the effects of pacing rate on force generation. The model reproduces transitions seen in force generation due to changes in pacing that cannot be simulated by previous models. Simulation of such complex phenomena requires an interplay of both RyR adaptation and the degree of SR Ca2+ loading. This model, therefore, shows improved behavior over existing models that lack detailed descriptions of subcellular Ca2+ regulatory mechanisms.&lt;/para&gt;&#xD;
      &lt;para&gt;The original paper reference is cited below:&lt;/para&gt;&#xD;
      &lt;para&gt;&#xD;
        Cardiac Calcium Dynamics: The Roles of Ryanodine Receptor Adaptation and Sarcoplasmic Reticulum Load, M. Saleet Jafri, J. Jeremy Rice and Raimond L. Winslow, 1998,&#xD;
        &lt;emphasis&gt;Biophysical Journal&lt;/emphasis&gt;&#xD;
        , 74, 1149-1168.&#xD;
        &lt;ulink url="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;amp;db=PubMed&amp;amp;list_uids=9512016&amp;amp;dopt=Abstract"&gt;PubMed ID: 9512016&lt;/ulink&gt;&#xD;
      &lt;/para&gt;&#xD;
      &lt;informalfigure float="0" id="fig_cell_diagram"&gt;&#xD;
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          &lt;imageobject&gt;&#xD;
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              &lt;title&gt;cell diagram of the Jafri-Rice-Winslow model showing ionic currents, pumps and exchangers within the sarcolemma and the sarcoplasmic reticulum&lt;/title&gt;&#xD;
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            &lt;imagedata fileref="jafri_rice_winslow_1998.png" /&gt;&#xD;
          &lt;/imageobject&gt;&#xD;
        &lt;/mediaobject&gt;&#xD;
        &lt;caption&gt;A schematic diagram describing the current flows across the cell membrane that are captured in the Jafri-Rice-Winslow model.&lt;/caption&gt;&#xD;
      &lt;/informalfigure&gt;&#xD;
    &lt;/sect1&gt;&#xD;
  &lt;/article&gt;&#xD;
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    <dcterms:description>calcium reversal potential</dcterms:description>
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    <dcterms:description>buffering flux of calcium binding to troponin</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
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    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current_h_gate.beta_h">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.Nai">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_0">
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.y">
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.Ca_JSR">
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_c_minus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>ryanodine receptor PC2 - PO1 rate constant</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.Nao">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.f_">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>transition rate into open state</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.g_Kp">
    <dcterms:description>maximum plateu potassium channel conductance</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.X">
    <dcterms:description>time-dependent potassium current activation gate</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.g_K">
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    <dcterms:description>membrane potential</dcterms:description>
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  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.j">
    <dcterms:description>fast sodium current channel slow inactivation gate</dcterms:description>
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    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_NaCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.Nai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.stim_end">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.alpha_a">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.v3">
    <dcterms:description>maximum SERCA pump rate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.alpha">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.J_xfer">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
    <dcterms:description>calcium transfer flux from subspace to myoplasm</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.J_htrpn">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
    <dcterms:description>buffering flux of calcium binding to high-affinity troponin binding sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.K_mKo">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>potassium half-saturation constant for sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.g">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>transition rate out of open state</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.Nao">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current_h_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.Am">
    <dcterms:description>capacitive membrane area</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.Ko">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.I_ns_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific sodium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_htrpn_plus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>calcium on rate constant for troponin high-affinity sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-dependent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.E_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>time-independent potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.LTRPNCa">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_14"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of myoplasmic calcium-bound low-affinity troponin binding sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.HTRPNCa">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_14"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of myoplasmic calcium-bound high-affinity troponin binding sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_X_gate.beta_X">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.v2">
    <dcterms:description>calcium leak rate constant from the network sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.g_Cab">
    <dcterms:description>maximum background calcium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem_Cai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.K_mNai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>sodium half-saturation constant for sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_Xi_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.P_Ca">
    <dcterms:description>L-type calcium channel permeability to calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.Ca_SS">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_4">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_5">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62358"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in subspace</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.Cai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.Nai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.I_ns_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific potassium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.i_Ca_L_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>potassium-activated L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.K_mCa">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.tau_tr">
    <dcterms:description>time constant for transfer from network sarcoplasmic reticulum to junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.K_mCMDN">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_Na_b">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current_K1_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel_y_gate.y_infinity">
    <dcterms:description>steady state function of L-type calcium current inactivation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.B_SS">
    <dcterms:description>rate of change in free calcium concentration in the subspace</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.K_m_ns_Ca">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for non-specific current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.Ki">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_8"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.m">
    <dcterms:description>fast sodium current channel activation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>time-dependent potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_ltrpn_minus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>calcium off rate constant for troponin low-affinity sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.J_ltrpn">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
    <dcterms:description>buffering flux of calcium binding to low-affinity troponin binding sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_a_minus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>ryanodine receptor PO1 - PC1 rate constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.P_K">
    <dcterms:description>L-type calcium channel permeability to potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.CMDN_tot">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_16">
        <bqbiol:isPartOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_1"/>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62343"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>total concentration of myoplasmic calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.Ki">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_8"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.beta_b">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.Nai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.Ki">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_8"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>transition rate into open state</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel_y_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.LTRPN_tot">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_14"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>total concentration of myoplasmic low-affinity troponin binding sites</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.Ko">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_background_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_background_current.i_Na_b">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_NaCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.Ca_SS">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_4"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in subspace</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.J_tr">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
    <dcterms:description>calcium transfer flux from the network sarcoplasmic reticulum to the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.g_K1_max">
    <dcterms:description>maximum time-independent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.Cao">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.omega">
    <dcterms:description>mode transition parameter</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.Ko">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C2">
    <dcterms:description>L-type calcium channel closed state mode normal</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane_V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sarcolemmal_calcium_pump.i_p_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sarcolemmal calcium pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_X_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.b">
    <dcterms:description>mode transition parameter</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.V_NSR">
    <dcterms:description>network sarcoplasmic reticulum volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_background_current.g_Nab">
    <dcterms:description>maximum background sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_X_gate.X">
    <dcterms:description>time-dependent potassium current activation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.O_Ca">
    <dcterms:description>L-type calcium channel conducting state mode calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.P_O2">
    <dcterms:description>fraction of channels in state PO2</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel_y_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.J_rel">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
    <dcterms:description>calcium release flux via ryanodine receptors</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.i_ns_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific calcium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.tau_xfer">
    <dcterms:description>time constant for transfer from subspace to myoplasm</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.P_ns_Ca">
    <dcterms:description>non-specific current channel permeability</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.i_NaCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_b_minus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>ryanodine receptor PO2 - PO1 rate constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_Ca_L_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>potassium-activated L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C3">
    <dcterms:description>L-type calcium channel closed state mode normal</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_a_plus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>ryanodine receptor PC1 - PO1 rate constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.i_ns_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific sodium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.p_k">
    <dcterms:description>L-type calcium channel permeability to potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_Ca_L_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium-activated L-type calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.EnsCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>non-specific calcium-activated current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.Nao">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.Cai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.P_O1">
    <dcterms:description>fraction of channels in state PO1</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current.K1_infinity">
    <dcterms:description>steady state function of time-independent potassium channel activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_p_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sarcolemmal calcium pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sarcolemmal_calcium_pump.Cai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_9"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_Xi_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel_y_gate.y">
    <dcterms:description>L-type calcium current inactivation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C0">
    <dcterms:description>L-type calcium channel closed state mode normal</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.stim_amplitude">
    <dcterms:description>stimulation amplitude</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_background_current.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.B_JSR">
    <dcterms:description>rate of change in free calcium concentration in the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.T">
    <dcterms:description>abolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#membrane.i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.V_myo">
    <dcterms:description>myoplasmic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_Kp">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>plateau potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.Nai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_c_plus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>ryanodine receptor PO1 - PC2 rate constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#non_specific_calcium_activated_current.Nai">
    <bqbiol:isPropertyOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.i_ns_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>non-specific potassium-activated current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current_j_gate.alpha_j">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.E_Kp">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>plateau potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#fast_sodium_current.i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.i_Ca_b">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.C1">
    <dcterms:description>L-type calcium channel closed state mode normal</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#sodium_potassium_pump.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.beta">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_dependent_potassium_current_Xi_gate.Xi">
    <dcterms:description>time-dependent potassium current inactivation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.a">
    <dcterms:description>mode transition parameter</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#Na_Ca_exchanger.k_NaCa">
    <dcterms:description>scaling factor of sodium-calcium exchange</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.CSQN_tot">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#entity_15">
        <bqbiol:isPartOf rdf:resource="./jafri_rice_winslow_1998_a.cellml#entity_11"/>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62353"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>total concentration of calsequestrin in the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#ionic_concentrations.V_myo">
    <dcterms:description>myoplasmic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#calcium_subsystem.k_b_plus">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
    <dcterms:description>ryanodine receptor PO1 - PO2 rate constant</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#time_independent_potassium_current_K1_gate.beta_K1">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#plateau_potassium_current.i_Kp">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>plateau potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./jafri_rice_winslow_1998_a.cellml#L_type_Ca_channel.gamma">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
</rdf:RDF>