Location: Single PASMC model (Gosak et al 2014) @ 887894c158d4 / Components / buildsrc / PASMC_test.txt

Author:

WeiweiAi <wai484@aucklanduni.ac.nz>

Date:

2022-06-13 11:44:41+12:00

Desc:

Modify the intracelluar K from 4.7 mM to 5.9 mM

Permanent Source URI:

https://models.cellml.org/workspace/83f/rawfile/887894c158d460d4505bd3fb26d23a7b939ca442/Components/buildsrc/PASMC_test.txt

def model PASMC_test as
    def import using "../cellLib/Components/units.cellml" for
        unit mM using unit mM;
        unit mV using unit mV;
        unit uM using unit uM;
    enddef;

    def import using "../Components/PASMC.cellml" for
        comp PASMC using comp PASMC;
    enddef;

    def import using "../Components/Para.cellml" for
        comp Para using comp Para;
    enddef;

    def import using "../cellLib/Protocols/X_clamp_protocol.cellml" for
        comp X_clamp_protocol using comp X_clamp_protocol;
    enddef;

    def import using "../cellLib/Components/time.cellml" for
        comp time using comp time_s;
    enddef;

    def comp output as
        var v_i: mV {pub: in};
        var s_i: uM {pub: in};
        var c_i: uM {pub: in};
        var K_out: mM {pub: in};
        var t: second {pub: in};
    enddef;

    def comp clamp_para as
        var t_ss: second {init: 10, pub: out};
        var X_Holding: mM {init: 5.9, pub: out};
        var t_act: second {init: 70, pub: out};
        var X_Test: mM {init: 81.2, pub: out};
    enddef;

    def map between PASMC and output for
        vars v_i and v_i;
        vars s_i and s_i;
        vars c_i and c_i;
    enddef;

    def map between PASMC and Para for
        vars gamma and gamma;
        vars vi_init and vi_init;
        vars ci_init and ci_init;
        vars si_init and si_init;
        vars R and R;
        vars F and F;
        vars T and T;
        vars G_Ki and G_Ki;
        vars wi_init and wi_init;
        vars lambda and lambda;
        vars c_w and c_w;
        vars v_Ca3 and v_Ca3;
        vars R_K and R_K;
        vars beta and beta;
        vars Ki and Ki;
        vars G_Cl and G_Cl;
        vars v_Cl and v_Cl;
        vars C_NKA and C_NKA;
        vars K_mK and K_mK;
        vars L and L;
        vars D and D;
        vars v_d and v_d;
        vars R_d and R_d;
        vars C and C;
        vars s_c and s_c;
        vars c_c and c_c;
        vars B and B;
        vars c_b and c_b;
        vars G_NCX and G_NCX;
        vars v_NCX and v_NCX;
        vars c_NCX and c_NCX;
        vars G_Ca and G_Ca;
        vars v_Ca1 and v_Ca1;
        vars v_Ca2 and v_Ca2;
        vars R_Ca and R_Ca;
    enddef;

    def map between PASMC and X_clamp_protocol for
        vars K_out and X;
    enddef;

    def map between PASMC and time for
        vars t and time;
    enddef;

    def map between output and X_clamp_protocol for
        vars K_out and X;
    enddef;

    def map between output and time for
        vars t and time;
    enddef;

    def map between clamp_para and X_clamp_protocol for
        vars t_ss and t_ss;
        vars X_Holding and X_Holding;
        vars t_act and t_act;
        vars X_Test and X_Test;
    enddef;

    def map between X_clamp_protocol and time for
        vars time and time;
    enddef;

enddef;