- Author:
- Shelley Fong <sfon036@UoA.auckland.ac.nz>
- Date:
- 2022-05-25 13:29:34+12:00
- Desc:
- Adding 3Hi and 2He to stoich for every reaction forward and reverse
- Permanent Source URI:
- https://models.cellml.org/workspace/87f/rawfile/b5d10e5281bc1d01b967551bd27b1132401868cf/BG_NBC.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="individual_NBC" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units_and_constants/units_BG.cellml">
<units name="mM" units_ref="mM"/>
<units name="fmol" units_ref="fmol"/>
<units name="per_fmol" units_ref="per_fmol"/>
<units name="J_per_mol" units_ref="J_per_mol"/>
<units name="fmol_per_sec" units_ref="fmol_per_sec"/>
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="fF" units_ref="fF"/>
<units name="fC" units_ref="fC"/>
<units name="per_second" units_ref="per_second"/>
<units name="per_sec" units_ref="per_sec"/>
<units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
<units name="fmol_per_L" units_ref="fmol_per_L"/>
<units name="pL" units_ref="pL"/>
</import>
<import xlink:href="units_and_constants/constants_BG.cellml">
<component component_ref="constants" name="constants"/>
</import>
<component name="environment">
<variable name="time" public_interface="out" units="second"/>
<!-- initial values-->
<variable initial_value="481.46" name="q_Na_i" public_interface="out" units="fmol"/>
<variable initial_value="725.48" name="q_Na_o" public_interface="out" units="fmol"/>
<variable initial_value="509.2" name="q_HCO3_i" public_interface="out" units="fmol"/>
<variable initial_value="122.295" name="q_HCO3_o" public_interface="out" units="fmol"/>
<!-- From submodule-->
<variable name="v_R61_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R12_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R23_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R34_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R45_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R56_NBC" public_interface="in" units="fmol_per_sec"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_Na_i</ci>
</apply>
<ci>v_R56_NBC</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_Na_o</ci>
</apply>
<apply>
<minus/>
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</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_HCO3_i</ci>
</apply>
<ci>v_R45_NBC</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
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</bvar>
<ci>q_HCO3_o</ci>
</apply>
<apply>
<minus/>
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</apply>
</apply>
</math>
</component>
<component name="NBC_parameters">
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<variable initial_value="956450" name="kappa_R12_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="359017" name="kappa_R23_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="3.81848" name="kappa_R34_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00628833" name="kappa_R45_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="16939.1" name="kappa_R56_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.857619" name="K_Na_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0198297" name="K_Na_o" public_interface="out" units="per_fmol"/>
<variable initial_value="14.556" name="K_HCO3_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000105565" name="K_HCO3_o" public_interface="out" units="per_fmol"/>
<variable initial_value="0.267757" name="K_S1_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="133.993" name="K_S2_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000587862" name="K_S3_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="33562.6" name="K_S4_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="7565.8" name="K_S5_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0476703" name="K_S6_NBC" public_interface="out" units="per_fmol"/>
</component>
<component name="NBC">
<variable name="time" public_interface="in" units="second"/>
<variable name="R" public_interface="in" units="J_per_K_per_mol"/>
<variable name="T" public_interface="in" units="kelvin"/>
<!-- parameters-->
<variable name="kappa_R61_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_R12_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_R23_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_R34_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_R45_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="kappa_R56_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="K_Na_i" public_interface="in" units="per_fmol"/>
<variable name="K_Na_o" public_interface="in" units="per_fmol"/>
<variable name="K_HCO3_i" public_interface="in" units="per_fmol"/>
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<variable name="K_S1_NBC" public_interface="in" units="per_fmol"/>
<variable name="K_S2_NBC" public_interface="in" units="per_fmol"/>
<variable name="K_S3_NBC" public_interface="in" units="per_fmol"/>
<variable name="K_S4_NBC" public_interface="in" units="per_fmol"/>
<variable name="K_S5_NBC" public_interface="in" units="per_fmol"/>
<variable name="K_S6_NBC" public_interface="in" units="per_fmol"/>
<!-- Input from global environment-->
<variable name="q_Na_i" public_interface="in" units="fmol"/>
<variable name="q_Na_o" public_interface="in" units="fmol"/>
<variable name="q_HCO3_i" public_interface="in" units="fmol"/>
<variable name="q_HCO3_o" public_interface="in" units="fmol"/>
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<variable initial_value="1.666e-4" name="q_S5_NBC" units="fmol"/>
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<!-- Constitutive parameters-->
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<variable name="mu_Na_o" units="J_per_mol"/>
<variable name="mu_HCO3_i" units="J_per_mol"/>
<variable name="mu_HCO3_o" units="J_per_mol"/>
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<variable name="mu_S2_NBC" units="J_per_mol"/>
<variable name="mu_S3_NBC" units="J_per_mol"/>
<variable name="mu_S4_NBC" units="J_per_mol"/>
<variable name="mu_S5_NBC" units="J_per_mol"/>
<variable name="mu_S6_NBC" units="J_per_mol"/>
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<variable name="v_R12_NBC" public_interface="out" units="fmol_per_sec"/>
<variable name="v_R23_NBC" public_interface="out" units="fmol_per_sec"/>
<variable name="v_R34_NBC" public_interface="out" units="fmol_per_sec"/>
<variable name="v_R45_NBC" public_interface="out" units="fmol_per_sec"/>
<variable name="v_R56_NBC" public_interface="out" units="fmol_per_sec"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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