Location: BG_AE @ e479536490c5 / BG_AE.cellml

Author:
Shelley Fong <sfon036@UoA.auckland.ac.nz>
Date:
2022-07-13 15:26:37+12:00
Desc:
Moving channel initial moles to main environment from channel component
Permanent Source URI:
https://models.cellml.org/workspace/882/rawfile/e479536490c5930360f79e4e2d44a90ed4a2cf38/BG_AE.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="individual_AE" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="units_and_constants/units_BG.cellml">
        <units name="mM" units_ref="mM"/>
        <units name="fmol" units_ref="fmol"/>
        <units name="per_fmol" units_ref="per_fmol"/>
        <units name="J_per_mol" units_ref="J_per_mol"/>
        <units name="fmol_per_sec" units_ref="fmol_per_sec"/>
        <units name="C_per_mol" units_ref="C_per_mol"/>
        <units name="fF" units_ref="fF"/>
        <units name="fC" units_ref="fC"/>
        <units name="per_second" units_ref="per_second"/>
        <units name="per_sec" units_ref="per_sec"/>
        <units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
        <units name="fmol_per_L" units_ref="fmol_per_L"/>
        <units name="pL" units_ref="pL"/>
    </import>
    <import xlink:href="units_and_constants/constants_BG.cellml">
        <component component_ref="constants" name="constants"/>
    </import>
    <component name="environment">
        <variable name="time" public_interface="out" units="second"/>
        <!-- initial values-->
        <variable initial_value="5.902" name="q_HCO3_i" public_interface="out" units="fmol"/>
        <variable initial_value="112.2952" name="q_HCO3_o" public_interface="out" units="fmol"/>
        <variable initial_value="824.6" name="q_Cl_i" public_interface="out" units="fmol"/>
        <variable initial_value="725.48" name="q_Cl_o" public_interface="out" units="fmol"/>
        <variable initial_value="1.666e-7" name="q_S1_AE" public_interface="out" units="fmol"/>
        <variable initial_value="1.666e-7" name="q_S2_AE" public_interface="out" units="fmol"/>
        <variable initial_value="1.666e-7" name="q_S3_AE" public_interface="out" units="fmol"/>
        <variable initial_value="1.666e-7" name="q_S4_AE" public_interface="out" units="fmol"/>
        <variable initial_value="1.666e-7" name="q_S5_AE" public_interface="out" units="fmol"/>
        <variable initial_value="1.666e-7" name="q_S6_AE" public_interface="out" units="fmol"/>
        <!-- From submodule-->
        <variable name="v_R61_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_R12_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_R23_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_R34_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_R45_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="v_R56_AE" public_interface="in" units="fmol_per_sec"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_HCO3_i</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R56_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_HCO3_o</ci>
                </apply>
                <ci>v_R12_AE</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_Cl_i</ci>
                </apply>
                <ci>v_R45_AE</ci>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_Cl_o</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R23_AE</ci>
                </apply>
            </apply>
        </math>
    </component>
    <component name="AE_parameters">
        <variable initial_value="0.0390374" name="kappa_R61_AE" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="124875" name="kappa_R12_AE" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="317575" name="kappa_R23_AE" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.0114249" name="kappa_R34_AE" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="312282" name="kappa_R45_AE" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="123101" name="kappa_R56_AE" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.072148" name="K_HCO3_i" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.526989" name="K_HCO3_o" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.0284406" name="K_Cl_i" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.207219" name="K_Cl_o" public_interface="out" units="per_fmol"/>
        <variable initial_value="8888.91" name="K_S1_AE" public_interface="out" units="per_fmol"/>
        <variable initial_value="2.93242" name="K_S2_AE" public_interface="out" units="per_fmol"/>
        <variable initial_value="30984.8" name="K_S3_AE" public_interface="out" units="per_fmol"/>
        <variable initial_value="31510" name="K_S4_AE" public_interface="out" units="per_fmol"/>
        <variable initial_value="2.96299" name="K_S5_AE" public_interface="out" units="per_fmol"/>
        <variable initial_value="9016.99" name="K_S6_AE" public_interface="out" units="per_fmol"/>
    </component>
    <component name="AE">
        <variable name="time" public_interface="in" units="second"/>
        <variable name="R" public_interface="in" units="J_per_K_per_mol"/>
        <variable name="T" public_interface="in" units="kelvin"/>
        <!-- parameters-->
        <variable name="kappa_R61_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_R12_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_R23_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_R34_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_R45_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="kappa_R56_AE" public_interface="in" units="fmol_per_sec"/>
        <variable name="K_HCO3_i" public_interface="in" units="per_fmol"/>
        <variable name="K_HCO3_o" public_interface="in" units="per_fmol"/>
        <variable name="K_Cl_i" public_interface="in" units="per_fmol"/>
        <variable name="K_Cl_o" public_interface="in" units="per_fmol"/>
        <variable name="K_S1_AE" public_interface="in" units="per_fmol"/>
        <variable name="K_S2_AE" public_interface="in" units="per_fmol"/>
        <variable name="K_S3_AE" public_interface="in" units="per_fmol"/>
        <variable name="K_S4_AE" public_interface="in" units="per_fmol"/>
        <variable name="K_S5_AE" public_interface="in" units="per_fmol"/>
        <variable name="K_S6_AE" public_interface="in" units="per_fmol"/>
        <!-- Input from global environment-->
        <variable name="q_HCO3_i" public_interface="in" units="fmol"/>
        <variable name="q_HCO3_o" public_interface="in" units="fmol"/>
        <variable name="q_Cl_i" public_interface="in" units="fmol"/>
        <variable name="q_Cl_o" public_interface="in" units="fmol"/>
        <variable name="q_S1_AE" public_interface="in" units="fmol"/>
        <variable name="q_S2_AE" public_interface="in" units="fmol"/>
        <variable name="q_S3_AE" public_interface="in" units="fmol"/>
        <variable name="q_S4_AE" public_interface="in" units="fmol"/>
        <variable name="q_S5_AE" public_interface="in" units="fmol"/>
        <variable name="q_S6_AE" public_interface="in" units="fmol"/>
        <!-- Constitutive parameters-->
        <variable name="mu_HCO3_i" units="J_per_mol"/>
        <variable name="mu_HCO3_o" units="J_per_mol"/>
        <variable name="mu_Cl_i" units="J_per_mol"/>
        <variable name="mu_Cl_o" units="J_per_mol"/>
        <variable name="mu_S1_AE" units="J_per_mol"/>
        <variable name="mu_S2_AE" units="J_per_mol"/>
        <variable name="mu_S3_AE" units="J_per_mol"/>
        <variable name="mu_S4_AE" units="J_per_mol"/>
        <variable name="mu_S5_AE" units="J_per_mol"/>
        <variable name="mu_S6_AE" units="J_per_mol"/>
        <variable name="v_R61_AE" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_R12_AE" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_R23_AE" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_R34_AE" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_R45_AE" public_interface="out" units="fmol_per_sec"/>
        <variable name="v_R56_AE" public_interface="out" units="fmol_per_sec"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>mu_HCO3_i</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_HCO3_i</ci>
                            <ci>q_HCO3_i</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_HCO3_o</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_HCO3_o</ci>
                            <ci>q_HCO3_o</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_Cl_i</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_Cl_i</ci>
                            <ci>q_Cl_i</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_Cl_o</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_Cl_o</ci>
                            <ci>q_Cl_o</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_S1_AE</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_S1_AE</ci>
                            <ci>q_S1_AE</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_S2_AE</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_S2_AE</ci>
                            <ci>q_S2_AE</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_S3_AE</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_S3_AE</ci>
                            <ci>q_S3_AE</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_S4_AE</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_S4_AE</ci>
                            <ci>q_S4_AE</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_S5_AE</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_S5_AE</ci>
                            <ci>q_S5_AE</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>mu_S6_AE</ci>
                <apply>
                    <times/>
                    <ci>R</ci>
                    <ci>T</ci>
                    <apply>
                        <ln/>
                        <apply>
                            <times/>
                            <ci>K_S6_AE</ci>
                            <ci>q_S6_AE</ci>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R61_AE</ci>
                <apply>
                    <times/>
                    <ci>kappa_R61_AE</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S6_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S1_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R12_AE</ci>
                <apply>
                    <times/>
                    <ci>kappa_R12_AE</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S1_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>mu_S2_AE</ci>
                                    <ci>mu_HCO3_o</ci>
                                </apply>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R23_AE</ci>
                <apply>
                    <times/>
                    <ci>kappa_R23_AE</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>mu_S2_AE</ci>
                                    <ci>mu_Cl_o</ci>
                                </apply>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S3_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R34_AE</ci>
                <apply>
                    <times/>
                    <ci>kappa_R34_AE</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S3_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S4_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R45_AE</ci>
                <apply>
                    <times/>
                    <ci>kappa_R45_AE</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S4_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>mu_S5_AE</ci>
                                    <ci>mu_Cl_i</ci>
                                </apply>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_R56_AE</ci>
                <apply>
                    <times/>
                    <ci>kappa_R56_AE</ci>
                    <apply>
                        <minus/>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <apply>
                                    <plus/>
                                    <ci>mu_S5_AE</ci>
                                    <ci>mu_HCO3_i</ci>
                                </apply>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                        <apply>
                            <exp/>
                            <apply>
                                <divide/>
                                <ci>mu_S6_AE</ci>
                                <apply>
                                    <times/>
                                    <ci>R</ci>
                                    <ci>T</ci>
                                </apply>
                            </apply>
                        </apply>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_S1_AE</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R61_AE</ci>
                    <ci>v_R12_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_S2_AE</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R12_AE</ci>
                    <ci>v_R23_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_S3_AE</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R23_AE</ci>
                    <ci>v_R34_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_S4_AE</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R34_AE</ci>
                    <ci>v_R45_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_S5_AE</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R45_AE</ci>
                    <ci>v_R56_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>q_S6_AE</ci>
                </apply>
                <apply>
                    <minus/>
                    <ci>v_R56_AE</ci>
                    <ci>v_R61_AE</ci>
                </apply>
            </apply>
        </math>
        <!-- check conservation -->
        <variable name="B_tot" units="fmol"/>
        <variable name="S_tot" units="fmol"/>
        <variable name="S1S6_tot" units="fmol"/>
        <variable name="Cl_tot" units="fmol"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>B_tot</ci>
                <apply>
                    <plus/>
                    <ci>q_HCO3_i</ci>
                    <ci>q_HCO3_o</ci>
                    <ci>q_S1_AE</ci>
                    <ci>q_S6_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>S1S6_tot</ci>
                <apply>
                    <plus/>
                    <ci>q_S1_AE</ci>
                    <ci>q_S6_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>S_tot</ci>
                <apply>
                    <plus/>
                    <ci>q_S1_AE</ci>
                    <ci>q_S2_AE</ci>
                    <ci>q_S3_AE</ci>
                    <ci>q_S4_AE</ci>
                    <ci>q_S5_AE</ci>
                    <ci>q_S6_AE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>Cl_tot</ci>
                <apply>
                    <plus/>
                    <ci>q_Cl_i</ci>
                    <ci>q_Cl_o</ci>
                    <ci>q_S3_AE</ci>
                    <ci>q_S4_AE</ci>
                </apply>
            </apply>
        </math>
    </component>
    <connection>
        <map_components component_1="environment" component_2="AE"/>
        <map_variables variable_1="time" variable_2="time"/>
        <map_variables variable_1="q_HCO3_i" variable_2="q_HCO3_i"/>
        <map_variables variable_1="q_HCO3_o" variable_2="q_HCO3_o"/>
        <map_variables variable_1="q_Cl_i" variable_2="q_Cl_i"/>
        <map_variables variable_1="q_Cl_o" variable_2="q_Cl_o"/>
        <map_variables variable_1="v_R61_AE" variable_2="v_R61_AE"/>
        <map_variables variable_1="v_R12_AE" variable_2="v_R12_AE"/>
        <map_variables variable_1="v_R23_AE" variable_2="v_R23_AE"/>
        <map_variables variable_1="v_R34_AE" variable_2="v_R34_AE"/>
        <map_variables variable_1="v_R45_AE" variable_2="v_R45_AE"/>
        <map_variables variable_1="v_R56_AE" variable_2="v_R56_AE"/>
        <map_variables variable_1="q_S1_AE" variable_2="q_S1_AE"/>
        <map_variables variable_1="q_S2_AE" variable_2="q_S2_AE"/>
        <map_variables variable_1="q_S3_AE" variable_2="q_S3_AE"/>
        <map_variables variable_1="q_S4_AE" variable_2="q_S4_AE"/>
        <map_variables variable_1="q_S5_AE" variable_2="q_S5_AE"/>
        <map_variables variable_1="q_S6_AE" variable_2="q_S6_AE"/>
    </connection>
    <connection>
        <map_components component_1="AE" component_2="AE_parameters"/>
        <map_variables variable_1="kappa_R61_AE" variable_2="kappa_R61_AE"/>
        <map_variables variable_1="kappa_R12_AE" variable_2="kappa_R12_AE"/>
        <map_variables variable_1="kappa_R23_AE" variable_2="kappa_R23_AE"/>
        <map_variables variable_1="kappa_R34_AE" variable_2="kappa_R34_AE"/>
        <map_variables variable_1="kappa_R45_AE" variable_2="kappa_R45_AE"/>
        <map_variables variable_1="kappa_R56_AE" variable_2="kappa_R56_AE"/>
        <map_variables variable_1="K_HCO3_i" variable_2="K_HCO3_i"/>
        <map_variables variable_1="K_HCO3_o" variable_2="K_HCO3_o"/>
        <map_variables variable_1="K_Cl_i" variable_2="K_Cl_i"/>
        <map_variables variable_1="K_Cl_o" variable_2="K_Cl_o"/>
        <map_variables variable_1="K_S1_AE" variable_2="K_S1_AE"/>
        <map_variables variable_1="K_S2_AE" variable_2="K_S2_AE"/>
        <map_variables variable_1="K_S3_AE" variable_2="K_S3_AE"/>
        <map_variables variable_1="K_S4_AE" variable_2="K_S4_AE"/>
        <map_variables variable_1="K_S5_AE" variable_2="K_S5_AE"/>
        <map_variables variable_1="K_S6_AE" variable_2="K_S6_AE"/>
    </connection>
    <connection>
        <map_components component_1="constants" component_2="AE"/>
        <map_variables variable_1="R" variable_2="R"/>
        <map_variables variable_1="T" variable_2="T"/>
    </connection>
</model>