- Author:
- Shelley Fong <s.fong@auckland.ac.nz>
- Date:
- 2021-11-02 08:49:20+13:00
- Desc:
- Adding units and constants
- Permanent Source URI:
- https://models.cellml.org/workspace/8a0/rawfile/0281912bd43aaacea01b09c45ea723338bc1d5a9/FCU_EC_coupling.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="FCU_EC_coupling" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units_and_constants/units_BG.cellml">
<units name="mM" units_ref="mM"/>
<units name="fmol" units_ref="fmol"/>
<units name="per_fmol" units_ref="per_fmol"/>
<units name="J_per_mol" units_ref="J_per_mol"/>
<units name="fmol_per_sec" units_ref="fmol_per_sec"/>
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="J_per_C" units_ref="J_per_C"/>
<units name="microm3" units_ref="microm3"/>
<units name="fF" units_ref="fF"/>
<units name="fC" units_ref="fC"/>
<units name="fA" units_ref="fA"/>
<units name="per_second" units_ref="per_second"/>
<units name="millivolt" units_ref="millivolt"/>
<units name="per_sec" units_ref="per_sec"/>
<units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
<units name="fmol_per_L" units_ref="fmol_per_L"/>
<units name="fmol_per_L_per_sec" units_ref="fmol_per_L_per_sec"/>
<units name="per_sec_per_fmol_per_L" units_ref="per_sec_per_fmol_per_L"/>
<units name="uM" units_ref="uM"/>
<units name="mM_per_sec" units_ref="mM_per_sec"/>
<units name="uM_per_sec" units_ref="uM_per_sec"/>
<units name="pL" units_ref="pL"/>
<units name="m_to_u" units_ref="m_to_u"/>
</import>
<import xlink:href="units_and_constants/constants_BG.cellml">
<component component_ref="constants" name="constants"/>
</import>
<import xlink:href="PLB/BG_PLB.cellml">
<component component_ref="PLB" name="PLB"/>
</import>
<import xlink:href="SERCA/BG_SERCA.cellml">
<component component_ref="SERCA" name="SERCA"/>
</import>
<import xlink:href="RyR/BG_RyR.cellml">
<component component_ref="RyR" name="RyR"/>
</import>
<import xlink:href="LCC/BG_LCC.cellml">
<component component_ref="LCC" name="LCC"/>
</import>
<component name="BG_parameters">
<variable initial_value="45.5263" name="kappa_PLBph1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="6.55904" name="kappa_PLBph2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.386674" name="kappa_PLBd1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.21269" name="kappa_PLBd2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="431.435" name="kappa_Inh" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0108383" name="kappa_SERCA_R1_2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="192.314" name="kappa_SERCA_R2_4" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.00791e+08" name="kappa_SERCA_R2_2a" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="192.314" name="kappa_SERCA_R4_5" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1072.41" name="kappa_SERCA_R5_6" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8.43318e+06" name="kappa_SERCA_R6_8" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.22619e+06" name="kappa_SERCA_R8_9" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.22619e+06" name="kappa_SERCA_R9_10" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00890543" name="kappa_SERCA_R10_1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="34574.2" name="kappa_RyR" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8.83262" name="kappa_OC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.12618" name="kappa_CCI" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="883.262" name="kappa_CII" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="73.6052" name="kappa_IO" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="115.689" name="kappa_Ca1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="216.336" name="kappa_Ca2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.160891" name="kappa_K1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.300862" name="kappa_K2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="132.798" name="kappa_d000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="3.27634" name="kappa_d010" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="6.12666" name="kappa_d020" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.525901" name="kappa_d001" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0129748" name="kappa_d011" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0242625" name="kappa_d021" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.244648" name="kappa_f1_000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.21486" name="kappa_f1_100" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.000968841" name="kappa_f1_001" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00481102" name="kappa_f1_101" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.448058" name="kappa_f2_000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.22495" name="kappa_f2_100" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00177438" name="kappa_f2_001" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00881111" name="kappa_f2_101" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1258.66" name="kappa_f3_010" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="6250.17" name="kappa_f3_110" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="4.98447" name="kappa_f3_011" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="24.7516" name="kappa_f3_111" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="180068" name="kappa_fCa000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="894171" name="kappa_fCa100" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="4442.55" name="kappa_fCa010" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="22060.6" name="kappa_fCa110" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8307.45" name="kappa_fCa020" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="41252.7" name="kappa_fCa120" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00235741" name="K_PLB" public_interface="out" units="per_fmol"/>
<variable initial_value="0.395191" name="K_PKACI" public_interface="out" units="per_fmol"/>
<variable initial_value="0.638527" name="K_PLB_PKACI" public_interface="out" units="per_fmol"/>
<variable initial_value="0.361989" name="K_PP1" public_interface="out" units="per_fmol"/>
<variable initial_value="0.203757" name="K_PLBp_PP1" public_interface="out" units="per_fmol"/>
<variable initial_value="0.326014" name="K_PLBp" public_interface="out" units="per_fmol"/>
<variable initial_value="5.41093" name="K_Ip" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0673793" name="K_Ip_PP1" public_interface="out" units="per_fmol"/>
<variable initial_value="99.4026" name="K_P1_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="5.40736" name="K_P2_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="7.46995" name="K_P2a_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="3.91498e+06" name="K_P4_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0688518" name="K_P5_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="447.967" name="K_P6_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="3.64069" name="K_P8_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="614.023" name="K_P9_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="66.9176" name="K_P10_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="3684.23" name="K_H" public_interface="out" units="per_fmol"/>
<variable initial_value="27.1814" name="K_Ca_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.143954" name="K_Ca_sr" public_interface="out" units="per_fmol"/>
<variable initial_value="20.3153" name="K_MgATP" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000118208" name="K_MgADP" public_interface="out" units="per_fmol"/>
<variable initial_value="0.142238" name="K_Pi" public_interface="out" units="per_fmol"/>
<variable initial_value="5.40528" name="K_Ca_SR" public_interface="out" units="per_fmol"/>
<variable initial_value="5.40528" name="K_Ca_di" public_interface="out" units="per_fmol"/>
<variable initial_value="115.191" name="K_C_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="1.15191" name="K_CI_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="0.00197471" name="K_I_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="0.197471" name="K_O_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0113152" name="K_Cai" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0113152" name="K_Cao" public_interface="out" units="per_fmol"/>
<variable initial_value="0.00639576" name="K_Ki" public_interface="out" units="per_fmol"/>
<variable initial_value="0.00639576" name="K_Ko" public_interface="out" units="per_fmol"/>
<variable initial_value="0.106553" name="K_000_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="4.31886" name="K_010_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="2.30959" name="K_020_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0214576" name="K_100_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="0.86973" name="K_110_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="0.465103" name="K_120_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="26.9063" name="K_001_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="1090.58" name="K_011_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="583.207" name="K_021_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="5.41838" name="K_101_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="219.621" name="K_111_LCC" public_interface="out" units="per_fmol"/>
<variable initial_value="117.446" name="K_121_LCC" public_interface="out" units="per_fmol"/>
</component>
<component name="environment">
<variable name="time" public_interface="out" units="second"/>
<variable initial_value="34.4" name="vol_myo" public_interface="out" units="pL"/>
<variable initial_value="500" name="freq" units="dimensionless"/>
<!-- stimulus
ramp UP and ramp DOWN-->
<variable initial_value="3.5e-4" name="stimSt" units="second"/>
<variable initial_value="0.25e-4" name="stimDur" units="second"/>
<variable initial_value="1.8e-4" name="tRamp" units="second"/>
<variable initial_value="1e1" name="stimMag" units="fmol"/>
<variable initial_value="1e-5" name="stimHolding" units="fmol"/>
<variable name="m" units="fmol_per_sec"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>m</ci>
<apply>
<divide/>
<ci>stimMag</ci>
<ci>tRamp</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_L_B1_init</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>stimHolding</ci>
<apply>
<times/>
<ci>m</ci>
<apply>
<plus/>
<apply>
<minus/>
<ci>time</ci>
<ci>stimSt</ci>
</apply>
<ci>tRamp</ci>
</apply>
</apply>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>time</ci>
<ci>stimSt</ci>
</apply>
<apply>
<gt/>
<ci>time</ci>
<apply>
<minus/>
<ci>stimSt</ci>
<ci>tRamp</ci>
</apply>
</apply>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>stimMag</ci>
<ci>stimHolding</ci>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>time</ci>
<ci>stimSt</ci>
</apply>
<apply>
<lt/>
<ci>time</ci>
<apply>
<plus/>
<ci>stimSt</ci>
<ci>stimDur</ci>
</apply>
</apply>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>stimHolding</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>m</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<ci>time</ci>
<ci>stimSt</ci>
</apply>
<ci>tRamp</ci>
</apply>
<ci>stimDur</ci>
</apply>
</apply>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>time</ci>
<apply>
<plus/>
<ci>stimSt</ci>
<ci>tRamp</ci>
<ci>stimDur</ci>
</apply>
</apply>
<apply>
<geq/>
<ci>time</ci>
<apply>
<plus/>
<ci>stimSt</ci>
<ci>stimDur</ci>
</apply>
</apply>
</apply>
</piece>
<otherwise>
<ci>stimHolding</ci>
</otherwise>
</piecewise>
</apply>
</math>
<variable initial_value="1e-888" name="q_PLB_init" units="fmol"/>
<variable initial_value="1e-888" name="q_PKACI_init" units="fmol"/>
<variable initial_value="1e-888" name="q_PLB_PKACI_init" units="fmol"/>
<variable initial_value="1e-888" name="q_PP1_init" units="fmol"/>
<variable initial_value="1e-888" name="q_PLBp_PP1_init" units="fmol"/>
<variable initial_value="1e-888" name="q_PLBp_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ip_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ip_PP1_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P1_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P2_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P2a_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P4_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P5_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P6_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P8_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P9_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_P10_SERCA_init" units="fmol"/>
<variable initial_value="1e-888" name="q_H_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ca_i_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ca_sr_init" units="fmol"/>
<variable initial_value="1e-888" name="q_MgATP_init" units="fmol"/>
<variable initial_value="1e-888" name="q_MgADP_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Pi_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ca_SR_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ca_di_init" units="fmol"/>
<variable initial_value="1e-888" name="q_C_RyR_init" units="fmol"/>
<variable initial_value="1e-888" name="q_CI_RyR_init" units="fmol"/>
<variable initial_value="1e-888" name="q_I_RyR_init" units="fmol"/>
<variable initial_value="1e-888" name="q_O_RyR_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Cai_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Cao_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ki_init" units="fmol"/>
<variable initial_value="1e-888" name="q_Ko_init" units="fmol"/>
<variable initial_value="1e-888" name="q_000_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_010_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_020_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_100_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_110_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_120_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_001_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_011_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_021_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_101_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_111_LCC_init" units="fmol"/>
<variable initial_value="1e-888" name="q_121_LCC_init" units="fmol"/>
<!-- mass conservation checks-->
<variable name="L_B1_T" units="fmol"/>
<variable name="R_B1_T" units="fmol"/>
<variable name="Gs_T" units="fmol"/>
<variable name="adenosine_T" units="fmol"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>L_B1_T</ci>
<apply>
<plus/>
<ci>q_L_B1</ci>
<ci>q_LR_B1Gs</ci>
<ci>q_LR_B1</ci>
<ci>q_LR_B1_aby</ci>
<ci>q_LR_B1_aby_T</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>R_B1_T</ci>
<apply>
<plus/>
<ci>q_R_B1</ci>
<ci>q_R_B1Gs</ci>
<ci>q_LR_B1</ci>
<ci>q_LR_B1Gs</ci>
<ci>q_R_B1_aby</ci>
<ci>q_R_B1_aby_T</ci>
<ci>q_LR_B1_aby</ci>
<ci>q_LR_B1_aby_T</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Gs_T</ci>
<apply>
<plus/>
<ci>q_Gs</ci>
<ci>q_R_B1Gs</ci>
<ci>q_LR_B1Gs</ci>
<ci>q_a_Gs_GTP</ci>
<ci>q_a_Gs_GDP</ci>
<ci>q_R_B1_aby</ci>
<ci>q_R_B1_aby_T</ci>
<ci>q_LR_B1_aby</ci>
<ci>q_LR_B1_aby_T</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>adenosine_T</ci>
<apply>
<plus/>
<ci>q_cAMP</ci>
<ci>q_PDE_cAMP</ci>
<ci>q_five_AMP</ci>
<ci>q_ATP</ci>
<ci>q_AC_ATP</ci>
<ci>q_a_Gs_GTP_AC_ATP</ci>
<ci>q_FSK_AC_ATP</ci>
</apply>
</apply>
</math>
<!-- Global value-->
<variable name="q_PLB" public_interface="out" units="fmol"/>
<variable name="q_PKACI" public_interface="out" units="fmol"/>
<variable name="q_PLB_PKACI" public_interface="out" units="fmol"/>
<variable name="q_PP1" public_interface="out" units="fmol"/>
<variable name="q_PLBp_PP1" public_interface="out" units="fmol"/>
<variable name="q_PLBp" public_interface="out" units="fmol"/>
<variable name="q_Ip" public_interface="out" units="fmol"/>
<variable name="q_Ip_PP1" public_interface="out" units="fmol"/>
<variable name="q_P1_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P2_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P2a_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P4_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P5_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P6_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P8_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P9_SERCA" public_interface="out" units="fmol"/>
<variable name="q_P10_SERCA" public_interface="out" units="fmol"/>
<variable name="q_H" public_interface="out" units="fmol"/>
<variable name="q_Ca_i" public_interface="out" units="fmol"/>
<variable name="q_Ca_sr" public_interface="out" units="fmol"/>
<variable name="q_MgATP" public_interface="out" units="fmol"/>
<variable name="q_MgADP" public_interface="out" units="fmol"/>
<variable name="q_Pi" public_interface="out" units="fmol"/>
<variable name="q_Ca_SR" public_interface="out" units="fmol"/>
<variable name="q_Ca_di" public_interface="out" units="fmol"/>
<variable name="q_C_RyR" public_interface="out" units="fmol"/>
<variable name="q_CI_RyR" public_interface="out" units="fmol"/>
<variable name="q_I_RyR" public_interface="out" units="fmol"/>
<variable name="q_O_RyR" public_interface="out" units="fmol"/>
<variable name="q_Cai" public_interface="out" units="fmol"/>
<variable name="q_Cao" public_interface="out" units="fmol"/>
<variable name="q_Ki" public_interface="out" units="fmol"/>
<variable name="q_Ko" public_interface="out" units="fmol"/>
<variable name="q_000_LCC" public_interface="out" units="fmol"/>
<variable name="q_010_LCC" public_interface="out" units="fmol"/>
<variable name="q_020_LCC" public_interface="out" units="fmol"/>
<variable name="q_100_LCC" public_interface="out" units="fmol"/>
<variable name="q_110_LCC" public_interface="out" units="fmol"/>
<variable name="q_120_LCC" public_interface="out" units="fmol"/>
<variable name="q_001_LCC" public_interface="out" units="fmol"/>
<variable name="q_011_LCC" public_interface="out" units="fmol"/>
<variable name="q_021_LCC" public_interface="out" units="fmol"/>
<variable name="q_101_LCC" public_interface="out" units="fmol"/>
<variable name="q_111_LCC" public_interface="out" units="fmol"/>
<variable name="q_121_LCC" public_interface="out" units="fmol"/>
<!-- PLB imports-->
<variable name="q_PLB_mPLB" public_interface="in" units="fmol"/>
<variable name="q_PKACI_mPLB" public_interface="in" units="fmol"/>
<variable name="q_PLB_PKACI_mPLB" public_interface="in" units="fmol"/>
<variable name="q_PP1_mPLB" public_interface="in" units="fmol"/>
<variable name="q_PLBp_PP1_mPLB" public_interface="in" units="fmol"/>
<variable name="q_PLBp_mPLB" public_interface="in" units="fmol"/>
<variable name="q_Ip_mPLB" public_interface="in" units="fmol"/>
<variable name="q_Ip_PP1_mPLB" public_interface="in" units="fmol"/>
<!-- SERCA imports-->
<variable name="q_P1_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P2_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P2a_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P4_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P5_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P6_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P8_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P9_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_P10_SERCA_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_H_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_Ca_i_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_Ca_sr_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_MgATP_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_MgADP_mSERCA" public_interface="in" units="fmol"/>
<variable name="q_Pi_mSERCA" public_interface="in" units="fmol"/>
<!-- RyR imports-->
<variable name="q_Ca_SR_mRyR" public_interface="in" units="fmol"/>
<variable name="q_Ca_di_mRyR" public_interface="in" units="fmol"/>
<variable name="q_C_RyR_mRyR" public_interface="in" units="fmol"/>
<variable name="q_CI_RyR_mRyR" public_interface="in" units="fmol"/>
<variable name="q_I_RyR_mRyR" public_interface="in" units="fmol"/>
<variable name="q_O_RyR_mRyR" public_interface="in" units="fmol"/>
<!-- LCC imports-->
<variable name="q_Cai_mLCC" public_interface="in" units="fmol"/>
<variable name="q_Cao_mLCC" public_interface="in" units="fmol"/>
<variable name="q_Ki_mLCC" public_interface="in" units="fmol"/>
<variable name="q_Ko_mLCC" public_interface="in" units="fmol"/>
<variable name="q_000_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_010_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_020_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_100_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_110_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_120_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_001_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_011_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_021_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_101_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_111_LCC_mLCC" public_interface="in" units="fmol"/>
<variable name="q_121_LCC_mLCC" public_interface="in" units="fmol"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>q_PLB</ci>
<apply>
<plus/>
<ci>q_PLB_init</ci>
<ci>q_PLB_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_PKACI</ci>
<apply>
<plus/>
<ci>q_PKACI_init</ci>
<ci>q_PKACI_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_PLB_PKACI</ci>
<apply>
<plus/>
<ci>q_PLB_PKACI_init</ci>
<ci>q_PLB_PKACI_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_PP1</ci>
<apply>
<plus/>
<ci>q_PP1_init</ci>
<ci>q_PP1_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_PLBp_PP1</ci>
<apply>
<plus/>
<ci>q_PLBp_PP1_init</ci>
<ci>q_PLBp_PP1_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_PLBp</ci>
<apply>
<plus/>
<ci>q_PLBp_init</ci>
<ci>q_PLBp_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ip</ci>
<apply>
<plus/>
<ci>q_Ip_init</ci>
<ci>q_Ip_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ip_PP1</ci>
<apply>
<plus/>
<ci>q_Ip_PP1_init</ci>
<ci>q_Ip_PP1_mPLB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P1_SERCA</ci>
<apply>
<plus/>
<ci>q_P1_SERCA_init</ci>
<ci>q_P1_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P2_SERCA</ci>
<apply>
<plus/>
<ci>q_P2_SERCA_init</ci>
<ci>q_P2_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P2a_SERCA</ci>
<apply>
<plus/>
<ci>q_P2a_SERCA_init</ci>
<ci>q_P2a_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P4_SERCA</ci>
<apply>
<plus/>
<ci>q_P4_SERCA_init</ci>
<ci>q_P4_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P5_SERCA</ci>
<apply>
<plus/>
<ci>q_P5_SERCA_init</ci>
<ci>q_P5_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P6_SERCA</ci>
<apply>
<plus/>
<ci>q_P6_SERCA_init</ci>
<ci>q_P6_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P8_SERCA</ci>
<apply>
<plus/>
<ci>q_P8_SERCA_init</ci>
<ci>q_P8_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P9_SERCA</ci>
<apply>
<plus/>
<ci>q_P9_SERCA_init</ci>
<ci>q_P9_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_P10_SERCA</ci>
<apply>
<plus/>
<ci>q_P10_SERCA_init</ci>
<ci>q_P10_SERCA_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_H</ci>
<apply>
<plus/>
<ci>q_H_init</ci>
<ci>q_H_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ca_i</ci>
<apply>
<plus/>
<ci>q_Ca_i_init</ci>
<ci>q_Ca_i_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ca_sr</ci>
<apply>
<plus/>
<ci>q_Ca_sr_init</ci>
<ci>q_Ca_sr_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_MgATP</ci>
<apply>
<plus/>
<ci>q_MgATP_init</ci>
<ci>q_MgATP_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_MgADP</ci>
<apply>
<plus/>
<ci>q_MgADP_init</ci>
<ci>q_MgADP_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Pi</ci>
<apply>
<plus/>
<ci>q_Pi_init</ci>
<ci>q_Pi_mSERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ca_SR</ci>
<apply>
<plus/>
<ci>q_Ca_SR_init</ci>
<ci>q_Ca_SR_mRyR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ca_di</ci>
<apply>
<plus/>
<ci>q_Ca_di_init</ci>
<ci>q_Ca_di_mRyR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_C_RyR</ci>
<apply>
<plus/>
<ci>q_C_RyR_init</ci>
<ci>q_C_RyR_mRyR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_CI_RyR</ci>
<apply>
<plus/>
<ci>q_CI_RyR_init</ci>
<ci>q_CI_RyR_mRyR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_I_RyR</ci>
<apply>
<plus/>
<ci>q_I_RyR_init</ci>
<ci>q_I_RyR_mRyR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_O_RyR</ci>
<apply>
<plus/>
<ci>q_O_RyR_init</ci>
<ci>q_O_RyR_mRyR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Cai</ci>
<apply>
<plus/>
<ci>q_Cai_init</ci>
<ci>q_Cai_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Cao</ci>
<apply>
<plus/>
<ci>q_Cao_init</ci>
<ci>q_Cao_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ki</ci>
<apply>
<plus/>
<ci>q_Ki_init</ci>
<ci>q_Ki_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_Ko</ci>
<apply>
<plus/>
<ci>q_Ko_init</ci>
<ci>q_Ko_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_000_LCC</ci>
<apply>
<plus/>
<ci>q_000_LCC_init</ci>
<ci>q_000_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_010_LCC</ci>
<apply>
<plus/>
<ci>q_010_LCC_init</ci>
<ci>q_010_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_020_LCC</ci>
<apply>
<plus/>
<ci>q_020_LCC_init</ci>
<ci>q_020_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_100_LCC</ci>
<apply>
<plus/>
<ci>q_100_LCC_init</ci>
<ci>q_100_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_110_LCC</ci>
<apply>
<plus/>
<ci>q_110_LCC_init</ci>
<ci>q_110_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_120_LCC</ci>
<apply>
<plus/>
<ci>q_120_LCC_init</ci>
<ci>q_120_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_001_LCC</ci>
<apply>
<plus/>
<ci>q_001_LCC_init</ci>
<ci>q_001_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_011_LCC</ci>
<apply>
<plus/>
<ci>q_011_LCC_init</ci>
<ci>q_011_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_021_LCC</ci>
<apply>
<plus/>
<ci>q_021_LCC_init</ci>
<ci>q_021_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_101_LCC</ci>
<apply>
<plus/>
<ci>q_101_LCC_init</ci>
<ci>q_101_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_111_LCC</ci>
<apply>
<plus/>
<ci>q_111_LCC_init</ci>
<ci>q_111_LCC_mLCC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>q_121_LCC</ci>
<apply>
<plus/>
<ci>q_121_LCC_init</ci>
<ci>q_121_LCC_mLCC</ci>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="environment" component_2="PLB"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_PLB_mPLB" variable_2="q_PLB"/>
<map_variables variable_1="q_PLB" variable_2="q_PLB_global"/>
<map_variables variable_1="q_PKACI_mPLB" variable_2="q_PKACI"/>
<map_variables variable_1="q_PKACI" variable_2="q_PKACI_global"/>
<map_variables variable_1="q_PLB_PKACI_mPLB" variable_2="q_PLB_PKACI"/>
<map_variables variable_1="q_PLB_PKACI" variable_2="q_PLB_PKACI_global"/>
<map_variables variable_1="q_PP1_mPLB" variable_2="q_PP1"/>
<map_variables variable_1="q_PP1" variable_2="q_PP1_global"/>
<map_variables variable_1="q_PLBp_PP1_mPLB" variable_2="q_PLBp_PP1"/>
<map_variables variable_1="q_PLBp_PP1" variable_2="q_PLBp_PP1_global"/>
<map_variables variable_1="q_PLBp_mPLB" variable_2="q_PLBp"/>
<map_variables variable_1="q_PLBp" variable_2="q_PLBp_global"/>
<map_variables variable_1="q_Ip_mPLB" variable_2="q_Ip"/>
<map_variables variable_1="q_Ip" variable_2="q_Ip_global"/>
<map_variables variable_1="q_Ip_PP1_mPLB" variable_2="q_Ip_PP1"/>
<map_variables variable_1="q_Ip_PP1" variable_2="q_Ip_PP1_global"/>
</connection>
<connection>
<map_components component_1="environment" component_2="SERCA"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_P1_SERCA_mSERCA" variable_2="q_P1_SERCA"/>
<map_variables variable_1="q_P1_SERCA" variable_2="q_P1_SERCA_global"/>
<map_variables variable_1="q_P2_SERCA_mSERCA" variable_2="q_P2_SERCA"/>
<map_variables variable_1="q_P2_SERCA" variable_2="q_P2_SERCA_global"/>
<map_variables variable_1="q_P2a_SERCA_mSERCA" variable_2="q_P2a_SERCA"/>
<map_variables variable_1="q_P2a_SERCA" variable_2="q_P2a_SERCA_global"/>
<map_variables variable_1="q_P4_SERCA_mSERCA" variable_2="q_P4_SERCA"/>
<map_variables variable_1="q_P4_SERCA" variable_2="q_P4_SERCA_global"/>
<map_variables variable_1="q_P5_SERCA_mSERCA" variable_2="q_P5_SERCA"/>
<map_variables variable_1="q_P5_SERCA" variable_2="q_P5_SERCA_global"/>
<map_variables variable_1="q_P6_SERCA_mSERCA" variable_2="q_P6_SERCA"/>
<map_variables variable_1="q_P6_SERCA" variable_2="q_P6_SERCA_global"/>
<map_variables variable_1="q_P8_SERCA_mSERCA" variable_2="q_P8_SERCA"/>
<map_variables variable_1="q_P8_SERCA" variable_2="q_P8_SERCA_global"/>
<map_variables variable_1="q_P9_SERCA_mSERCA" variable_2="q_P9_SERCA"/>
<map_variables variable_1="q_P9_SERCA" variable_2="q_P9_SERCA_global"/>
<map_variables variable_1="q_P10_SERCA_mSERCA" variable_2="q_P10_SERCA"/>
<map_variables variable_1="q_P10_SERCA" variable_2="q_P10_SERCA_global"/>
<map_variables variable_1="q_H_mSERCA" variable_2="q_H"/>
<map_variables variable_1="q_H" variable_2="q_H_global"/>
<map_variables variable_1="q_Ca_i_mSERCA" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i_global"/>
<map_variables variable_1="q_Ca_sr_mSERCA" variable_2="q_Ca_sr"/>
<map_variables variable_1="q_Ca_sr" variable_2="q_Ca_sr_global"/>
<map_variables variable_1="q_MgATP_mSERCA" variable_2="q_MgATP"/>
<map_variables variable_1="q_MgATP" variable_2="q_MgATP_global"/>
<map_variables variable_1="q_MgADP_mSERCA" variable_2="q_MgADP"/>
<map_variables variable_1="q_MgADP" variable_2="q_MgADP_global"/>
<map_variables variable_1="q_Pi_mSERCA" variable_2="q_Pi"/>
<map_variables variable_1="q_Pi" variable_2="q_Pi_global"/>
</connection>
<connection>
<map_components component_1="environment" component_2="RyR"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_Ca_SR_mRyR" variable_2="q_Ca_SR"/>
<map_variables variable_1="q_Ca_SR" variable_2="q_Ca_SR_global"/>
<map_variables variable_1="q_Ca_di_mRyR" variable_2="q_Ca_di"/>
<map_variables variable_1="q_Ca_di" variable_2="q_Ca_di_global"/>
<map_variables variable_1="q_C_RyR_mRyR" variable_2="q_C_RyR"/>
<map_variables variable_1="q_C_RyR" variable_2="q_C_RyR_global"/>
<map_variables variable_1="q_CI_RyR_mRyR" variable_2="q_CI_RyR"/>
<map_variables variable_1="q_CI_RyR" variable_2="q_CI_RyR_global"/>
<map_variables variable_1="q_I_RyR_mRyR" variable_2="q_I_RyR"/>
<map_variables variable_1="q_I_RyR" variable_2="q_I_RyR_global"/>
<map_variables variable_1="q_O_RyR_mRyR" variable_2="q_O_RyR"/>
<map_variables variable_1="q_O_RyR" variable_2="q_O_RyR_global"/>
</connection>
<connection>
<map_components component_1="environment" component_2="LCC"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_Cai_mLCC" variable_2="q_Cai"/>
<map_variables variable_1="q_Cai" variable_2="q_Cai_global"/>
<map_variables variable_1="q_Cao_mLCC" variable_2="q_Cao"/>
<map_variables variable_1="q_Cao" variable_2="q_Cao_global"/>
<map_variables variable_1="q_Ki_mLCC" variable_2="q_Ki"/>
<map_variables variable_1="q_Ki" variable_2="q_Ki_global"/>
<map_variables variable_1="q_Ko_mLCC" variable_2="q_Ko"/>
<map_variables variable_1="q_Ko" variable_2="q_Ko_global"/>
<map_variables variable_1="q_000_LCC_mLCC" variable_2="q_000_LCC"/>
<map_variables variable_1="q_000_LCC" variable_2="q_000_LCC_global"/>
<map_variables variable_1="q_010_LCC_mLCC" variable_2="q_010_LCC"/>
<map_variables variable_1="q_010_LCC" variable_2="q_010_LCC_global"/>
<map_variables variable_1="q_020_LCC_mLCC" variable_2="q_020_LCC"/>
<map_variables variable_1="q_020_LCC" variable_2="q_020_LCC_global"/>
<map_variables variable_1="q_100_LCC_mLCC" variable_2="q_100_LCC"/>
<map_variables variable_1="q_100_LCC" variable_2="q_100_LCC_global"/>
<map_variables variable_1="q_110_LCC_mLCC" variable_2="q_110_LCC"/>
<map_variables variable_1="q_110_LCC" variable_2="q_110_LCC_global"/>
<map_variables variable_1="q_120_LCC_mLCC" variable_2="q_120_LCC"/>
<map_variables variable_1="q_120_LCC" variable_2="q_120_LCC_global"/>
<map_variables variable_1="q_001_LCC_mLCC" variable_2="q_001_LCC"/>
<map_variables variable_1="q_001_LCC" variable_2="q_001_LCC_global"/>
<map_variables variable_1="q_011_LCC_mLCC" variable_2="q_011_LCC"/>
<map_variables variable_1="q_011_LCC" variable_2="q_011_LCC_global"/>
<map_variables variable_1="q_021_LCC_mLCC" variable_2="q_021_LCC"/>
<map_variables variable_1="q_021_LCC" variable_2="q_021_LCC_global"/>
<map_variables variable_1="q_101_LCC_mLCC" variable_2="q_101_LCC"/>
<map_variables variable_1="q_101_LCC" variable_2="q_101_LCC_global"/>
<map_variables variable_1="q_111_LCC_mLCC" variable_2="q_111_LCC"/>
<map_variables variable_1="q_111_LCC" variable_2="q_111_LCC_global"/>
<map_variables variable_1="q_121_LCC_mLCC" variable_2="q_121_LCC"/>
<map_variables variable_1="q_121_LCC" variable_2="q_121_LCC_global"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="PLB"/>
<map_variables variable_1="kappa_PLBph1" variable_2="kappa_PLBph1"/>
<map_variables variable_1="kappa_PLBph2" variable_2="kappa_PLBph2"/>
<map_variables variable_1="kappa_PLBd1" variable_2="kappa_PLBd1"/>
<map_variables variable_1="kappa_PLBd2" variable_2="kappa_PLBd2"/>
<map_variables variable_1="kappa_Inh" variable_2="kappa_Inh"/>
<map_variables variable_1="K_PLB" variable_2="K_PLB"/>
<map_variables variable_1="K_PKACI" variable_2="K_PKACI"/>
<map_variables variable_1="K_PLB_PKACI" variable_2="K_PLB_PKACI"/>
<map_variables variable_1="K_PP1" variable_2="K_PP1"/>
<map_variables variable_1="K_PLBp_PP1" variable_2="K_PLBp_PP1"/>
<map_variables variable_1="K_PLBp" variable_2="K_PLBp"/>
<map_variables variable_1="K_Ip" variable_2="K_Ip"/>
<map_variables variable_1="K_Ip_PP1" variable_2="K_Ip_PP1"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="SERCA"/>
<map_variables variable_1="kappa_SERCA_R1_2" variable_2="kappa_SERCA_R1_2"/>
<map_variables variable_1="kappa_SERCA_R2_4" variable_2="kappa_SERCA_R2_4"/>
<map_variables variable_1="kappa_SERCA_R2_2a" variable_2="kappa_SERCA_R2_2a"/>
<map_variables variable_1="kappa_SERCA_R4_5" variable_2="kappa_SERCA_R4_5"/>
<map_variables variable_1="kappa_SERCA_R5_6" variable_2="kappa_SERCA_R5_6"/>
<map_variables variable_1="kappa_SERCA_R6_8" variable_2="kappa_SERCA_R6_8"/>
<map_variables variable_1="kappa_SERCA_R8_9" variable_2="kappa_SERCA_R8_9"/>
<map_variables variable_1="kappa_SERCA_R9_10" variable_2="kappa_SERCA_R9_10"/>
<map_variables variable_1="kappa_SERCA_R10_1" variable_2="kappa_SERCA_R10_1"/>
<map_variables variable_1="K_P1_SERCA" variable_2="K_P1_SERCA"/>
<map_variables variable_1="K_P2_SERCA" variable_2="K_P2_SERCA"/>
<map_variables variable_1="K_P2a_SERCA" variable_2="K_P2a_SERCA"/>
<map_variables variable_1="K_P4_SERCA" variable_2="K_P4_SERCA"/>
<map_variables variable_1="K_P5_SERCA" variable_2="K_P5_SERCA"/>
<map_variables variable_1="K_P6_SERCA" variable_2="K_P6_SERCA"/>
<map_variables variable_1="K_P8_SERCA" variable_2="K_P8_SERCA"/>
<map_variables variable_1="K_P9_SERCA" variable_2="K_P9_SERCA"/>
<map_variables variable_1="K_P10_SERCA" variable_2="K_P10_SERCA"/>
<map_variables variable_1="K_H" variable_2="K_H"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Ca_sr" variable_2="K_Ca_sr"/>
<map_variables variable_1="K_MgATP" variable_2="K_MgATP"/>
<map_variables variable_1="K_MgADP" variable_2="K_MgADP"/>
<map_variables variable_1="K_Pi" variable_2="K_Pi"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="RyR"/>
<map_variables variable_1="kappa_RyR" variable_2="kappa_RyR"/>
<map_variables variable_1="kappa_OC" variable_2="kappa_OC"/>
<map_variables variable_1="kappa_CCI" variable_2="kappa_CCI"/>
<map_variables variable_1="kappa_CII" variable_2="kappa_CII"/>
<map_variables variable_1="kappa_IO" variable_2="kappa_IO"/>
<map_variables variable_1="K_Ca_SR" variable_2="K_Ca_SR"/>
<map_variables variable_1="K_Ca_di" variable_2="K_Ca_di"/>
<map_variables variable_1="K_C_RyR" variable_2="K_C_RyR"/>
<map_variables variable_1="K_CI_RyR" variable_2="K_CI_RyR"/>
<map_variables variable_1="K_I_RyR" variable_2="K_I_RyR"/>
<map_variables variable_1="K_O_RyR" variable_2="K_O_RyR"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="LCC"/>
<map_variables variable_1="kappa_Ca1" variable_2="kappa_Ca1"/>
<map_variables variable_1="kappa_Ca2" variable_2="kappa_Ca2"/>
<map_variables variable_1="kappa_K1" variable_2="kappa_K1"/>
<map_variables variable_1="kappa_K2" variable_2="kappa_K2"/>
<map_variables variable_1="kappa_d000" variable_2="kappa_d000"/>
<map_variables variable_1="kappa_d010" variable_2="kappa_d010"/>
<map_variables variable_1="kappa_d020" variable_2="kappa_d020"/>
<map_variables variable_1="kappa_d001" variable_2="kappa_d001"/>
<map_variables variable_1="kappa_d011" variable_2="kappa_d011"/>
<map_variables variable_1="kappa_d021" variable_2="kappa_d021"/>
<map_variables variable_1="kappa_f1_000" variable_2="kappa_f1_000"/>
<map_variables variable_1="kappa_f1_100" variable_2="kappa_f1_100"/>
<map_variables variable_1="kappa_f1_001" variable_2="kappa_f1_001"/>
<map_variables variable_1="kappa_f1_101" variable_2="kappa_f1_101"/>
<map_variables variable_1="kappa_f2_000" variable_2="kappa_f2_000"/>
<map_variables variable_1="kappa_f2_100" variable_2="kappa_f2_100"/>
<map_variables variable_1="kappa_f2_001" variable_2="kappa_f2_001"/>
<map_variables variable_1="kappa_f2_101" variable_2="kappa_f2_101"/>
<map_variables variable_1="kappa_f3_010" variable_2="kappa_f3_010"/>
<map_variables variable_1="kappa_f3_110" variable_2="kappa_f3_110"/>
<map_variables variable_1="kappa_f3_011" variable_2="kappa_f3_011"/>
<map_variables variable_1="kappa_f3_111" variable_2="kappa_f3_111"/>
<map_variables variable_1="kappa_fCa000" variable_2="kappa_fCa000"/>
<map_variables variable_1="kappa_fCa100" variable_2="kappa_fCa100"/>
<map_variables variable_1="kappa_fCa010" variable_2="kappa_fCa010"/>
<map_variables variable_1="kappa_fCa110" variable_2="kappa_fCa110"/>
<map_variables variable_1="kappa_fCa020" variable_2="kappa_fCa020"/>
<map_variables variable_1="kappa_fCa120" variable_2="kappa_fCa120"/>
<map_variables variable_1="K_Cai" variable_2="K_Cai"/>
<map_variables variable_1="K_Cao" variable_2="K_Cao"/>
<map_variables variable_1="K_Ki" variable_2="K_Ki"/>
<map_variables variable_1="K_Ko" variable_2="K_Ko"/>
<map_variables variable_1="K_000_LCC" variable_2="K_000_LCC"/>
<map_variables variable_1="K_010_LCC" variable_2="K_010_LCC"/>
<map_variables variable_1="K_020_LCC" variable_2="K_020_LCC"/>
<map_variables variable_1="K_100_LCC" variable_2="K_100_LCC"/>
<map_variables variable_1="K_110_LCC" variable_2="K_110_LCC"/>
<map_variables variable_1="K_120_LCC" variable_2="K_120_LCC"/>
<map_variables variable_1="K_001_LCC" variable_2="K_001_LCC"/>
<map_variables variable_1="K_011_LCC" variable_2="K_011_LCC"/>
<map_variables variable_1="K_021_LCC" variable_2="K_021_LCC"/>
<map_variables variable_1="K_101_LCC" variable_2="K_101_LCC"/>
<map_variables variable_1="K_111_LCC" variable_2="K_111_LCC"/>
<map_variables variable_1="K_121_LCC" variable_2="K_121_LCC"/>
</connection>
<connection>
<map_components component_1="constants" component_2="PLB"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="SERCA"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="RyR"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="LCC"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
</model>
