- Author:
- mtcooling <mtcooling.development@gmail.com>
- Date:
- 2015-08-24 10:57:56+12:00
- Desc:
- Split the annotation for the protocols into separate files in line with the metadata spec 2.0
- Permanent Source URI:
- https://models.cellml.org/workspace/cooling_hunter_crampin_2009/rawfile/e4e4bc1366292fd3387f8391e774271f5a4e9c14/calcium_ShenProtocol.cellml
<?xml version="1.0" encoding="iso-8859-1"?>
<model
name="calcium"
cmeta:id="calcium"
xmlns="http://www.cellml.org/cellml/1.1#"
xmlns:cellml="http://www.cellml.org/cellml/1.1#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
>
<!--
*******************************************************
*** U N I T S ***
*******************************************************
-->
<units name="s">
<unit units="second"/>
</units>
<units name="nM">
<unit units="mole" prefix="nano"/>
<unit units="liter" exponent="-1"/>
</units>
<units name="per_s">
<unit units="s" exponent="-1"/>
</units>
<units name="nM_per_s">
<unit units="nM"/>
<unit units="s" exponent="-1"/>
</units>
<!--
*********************************************************
*** C O M P O N E N T S ***
*********************************************************
-->
<component name="calcium">
<variable cmeta:id="v0" name="t" units="s" public_interface="in"/>
<variable cmeta:id="v1" name="Ca" units="nM" public_interface="out"/>
<variable cmeta:id="v2" name="stimEnd" units="s" initial_value="3600"/>
<variable cmeta:id="v3" name="trainPeriod" units="s" initial_value="50"/>
<variable cmeta:id="v4" name="timeInStim_modTrainPeriod" units="s"/>
<variable cmeta:id="v5" name="timeInStim_modPulsePeriod" units="s"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>timeInStim_modTrainPeriod</ci>
<apply>
<minus/>
<ci>t</ci>
<apply>
<times/>
<apply>
<floor/>
<apply>
<divide/>
<ci>t</ci>
<ci>trainPeriod</ci>
</apply>
</apply>
<ci>trainPeriod</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>timeInStim_modPulsePeriod</ci>
<apply>
<minus/>
<ci>t</ci>
<apply>
<times/>
<apply>
<floor/>
<apply>
<divide/>
<ci>t</ci>
<cn cellml:units="s">0.1</cn>
</apply>
</apply>
<cn cellml:units="s">0.1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Ca</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">1000</cn>
<apply>
<minus/>
<ci>timeInStim_modTrainPeriod</ci>
<cn cellml:units="s">5</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="nM_per_s">9.884615385</cn>
</apply>
</apply>
<cn cellml:units="nM">290.6923077</cn>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>timeInStim_modTrainPeriod</ci>
<cn cellml:units="s">5</cn>
</apply>
<apply>
<leq/>
<ci>timeInStim_modTrainPeriod</ci>
<cn cellml:units="s">5.02</cn>
</apply>
<apply>
<lt/>
<ci>t</ci>
<ci>stimEnd</ci>
</apply>
</apply>
</piece>
<piece>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">1000</cn>
<ci>timeInStim_modPulsePeriod</ci>
<cn cellml:units="nM_per_s">51.89423077</cn>
</apply>
<cn cellml:units="nM">290.6923077</cn>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>timeInStim_modTrainPeriod</ci>
<cn cellml:units="s">5</cn>
</apply>
<apply>
<leq/>
<ci>timeInStim_modPulsePeriod</ci>
<cn cellml:units="s">0.016</cn>
</apply>
<apply>
<lt/>
<ci>t</ci>
<ci>stimEnd</ci>
</apply>
</apply>
</piece>
<piece>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">1000</cn>
<apply>
<minus/>
<ci>timeInStim_modPulsePeriod</ci>
<cn cellml:units="s">0.016</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="nM_per_s">9.884615385</cn>
</apply>
</apply>
<cn cellml:units="nM">1121</cn>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>timeInStim_modTrainPeriod</ci>
<cn cellml:units="s">5</cn>
</apply>
<apply>
<gt/>
<ci>timeInStim_modPulsePeriod</ci>
<cn cellml:units="s">0.016</cn>
</apply>
<apply>
<lt/>
<ci>t</ci>
<ci>stimEnd</ci>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="nM">93</cn>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<rdf:RDF
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"
xmlns:bqs="http://www.cellml.org/bqs/1.0#"
xmlns:ro="http://www.obofoundry.org/ro/ro.owl#"
xmlns:opb="http://bhi.washington.edu/OPB#"
xmlns:j.0="http://imc.org/vCard/3.0#"
xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
xmlns:bqbiol="http://biomodels.net/biology-qualifiers/"
xmlns:bqmodel="http://biomodels.net/model-qualifiers/"
>
<rdf:Description rdf:about="#calcium">
<dc:creator rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Cooling</vCard:Family>
<vCard:Given>Michael</vCard:Given>
</vCard:N>
<vCard:EMAIL rdf:parseType="Resource">
<rdf:value>m.cooling@auckland.ac.nz</rdf:value>
<rdf:type rdf:resource="http://imc.org/vCard/3.0#internet" />
</vCard:EMAIL>
</dc:creator>
<dc:title>Cooling's calcium module for the Shen-derived protocol</dc:title>
</rdf:Description>
<rdf:Description rdf:ID="v0">
<semsim:refersTo rdf:resource="http://identifiers.org/opb/OPB_01361" />
</rdf:Description>
<rdf:Description rdf:ID="v1">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_1">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_0">
<ro:contained_in>
<rdf:Description rdf:about="#entity_1">
<semsim:refersTo rdf:resource="http://identifiers.org/fma/FMA:14067" />
</rdf:Description>
</ro:contained_in>
<semsim:refersTo rdf:resource="http://identifiers.org/chebi/CHEBI:39123" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:refersTo rdf:resource="http://identifiers.org/opb/OPB_00340" />
</rdf:Description>
</semsim:isComputationalComponentFor>
</rdf:Description>
</rdf:RDF>
</model>
