Limit cycle models for circadian rhythms based on transcriptional regulation in Drosophila and Neurospora
Mona
Zhu
Auckland Bioengineering Institute, The University of Auckland
Model Status
This is an import for the model "leloup_1999_1.1model.cellml". It is used to define a reoccuring structure within the model and may be used for multiple equations in the model. This file is known to run only in OpenCell in conjunction with the base file.
Model Structure
The original paper reference is cited below:
Limit Cycle Models for Circadian Rhythms Based on Transcriptional Regulation in Drosophila and Neurospora, Jean-Christophe Leloup, Didier Gonze, and Albert Goldbeter, 1999, Journal of Biological Rhythms, 14, 433-448. PubMed ID: 10643740
P0
non-phopshorylated PER
$\frac{d \mathrm{Y0}}{d \mathrm{time}}=\mathrm{ks}M+\mathrm{V2}\frac{\mathrm{Y1}}{\mathrm{K2}+\mathrm{Y1}}-\mathrm{V1}\frac{\mathrm{Y0}}{\mathrm{K1}+\mathrm{Y0}}+\mathrm{kd}\mathrm{Y0}$
Zhu
Xin Yue
Mona
xzhu055@aucklanduni.ac.nz
The University of Auckland
Auckland Bioengineering Institute
07-01-2011
Limit Cycle Models for Circadian Rhythms Based on Transcriptional Regulation in Drosophila and Neurospora