Model Mathematics

r_1NO = k_1NO r_4NO = k_4NO NO O_2m r_12aNO = k_12aNO {NO}^{2} O_2 r_12bNOp = k_12bNOp NO_2 NO r_12bNOm = k_12bNOm N2O3 r_14NO = k_14NO GSNO r_15NO = k_15NO CcOX NO r_16NO = k_16NO FeLn NO \frac{d}{d time} (NO) = (r_1NO - r_4NO - (2 r_12aNO) - r_12bNOp) + r_12bNOm + r_14NO - r_15NO - r_16NO \frac{d}{d time} (CcOX) = - r_15NO \frac{d}{d time} (NO_2) = (2 r_12aNO - r_12bNOp) + r_12bNOm

r_2NO = k_2NO r_5NO = k_5NO SOD O_2m r_10NO = k_10NO {GSNO}^{2} O_2m \frac{d}{d time} (O_2m) = r_2NO - r_4NO - r_5NO - r_10NO

r_6NO = k_6NO ONOO_m GSH r_7NO = k_7NO ONOO_m GPX r_8NO = k_8NO ONOO_m CO_2 r_9NO = k_9NO ONOO_m Cyt_c \frac{d}{d time} (ONOO_m) = r_4NO - r_6NO - r_7NO - r_8NO - r_9NO

FeLnNO = FeLn_0 - FeLn GSSG = \frac{GSH_0 - GSH - GSNO}{2} r_11NO = k_11NO N2O3 GSH r_m = \frac{v_m GSSG}{k_m + GSSG} r_17NO = k_17NO FeLnNO GSH \frac{d}{d time} (GSH) = (- r_6NO - r_11NO) + 2 r_m - r_17NO

\frac{d}{d time} (GSNO) = ((r_6NO - (2 r_10NO)) + r_11NO - r_14NO) + r_17NO

r_13NO = k_13NO N2O3 \frac{d}{d time} (N2O3) = (- r_11NO) + r_12bNOp - r_12bNOm - r_13NO

\frac{d}{d time} (FeLn) = (- r_16NO) + r_17NO