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Keizer, Levine, 1996
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Ryanodine Receptor Adaptation and Ca2+-Induced Ca2+ Release-Dependent Ca2+ Oscillations
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Model Mathematics
Component based math viewer is available
Component: environment
Component: P_C1
d
d
time
P_C1
=
-
ka
Cai
n
P_C1
+
ka_
P_O1
Component: P_O1
d
d
time
P_O1
=
ka
Cai
n
P_C1
+
-
ka_
P_O1
+
kb
Cai
m
P_O1
+
kb_
P_O2
+
-
kc
P_O1
+
kc_
P_C2
Component: P_O2
d
d
time
P_O2
=
-
kb
Cai
m
P_O1
+
kb_
P_O2
Component: P_C2
d
d
time
P_C2
=
kc
P_O1
-
kc_
P_C2
Component: P_O_slow
P_O_slow
=
w
1.0
+
Cai
Kb
3.0
1.0
+
Ka
Cai
4.0
+
Cai
Kb
3.0
w_init
=
1.0
-
P_C2
w_infinity_Cai
=
1.0
+
Ka
Cai
4.0
+
Cai
Kb
3.0
1.0
+
1.0
Kc
+
Ka
Cai
4.0
+
Cai
Kb
3.0
tau_Cai
=
w_infinity_Cai
kc_
Ka
=
ka_
ka
Kb
=
kb_
kb
Kc
=
kc_
kc
d
d
time
w
=
-
w
-
w_infinity_Cai
Cai
tau_Cai
Cai
Component: Cai
d
d
time
Cai
=
fi
v1
P_O_slow
+
v2
Cas
-
Cai
-
v3
Cai
2.0
Cai
2.0
+
K3
2.0
Cas
=
Co
-
Cai
c1
Component: constants
Source
Derived from workspace
Keizer, Levine, 1996
at changeset
5171ef60c764
.
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This work is licensed under a
Creative Commons Attribution 3.0 Unported License
.
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Ryanodine Receptor Adaptation and Ca2+-Induced Ca2+ Release-Dependent Ca2+ Oscillations