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Hodgkin, Huxley, 1952
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A quantitative description of membrane current and its application to conduction and excitation in nerve
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Model Mathematics
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Component: environment
Component: membrane
i_Stim
=
-
20
if
time
≥
10
∧
time
≦
10.5
0
otherwise
d
d
time
V
=
-
-
i_Stim
+
i_Na
+
i_K
+
i_L
Cm
Component: sodium_channel
E_Na
=
E_R
-
115
i_Na
=
g_Na
m
3
h
V
-
E_Na
Component: sodium_channel_m_gate
alpha_m
=
0.1
V
+
25
ⅇ
V
+
25
10
-
1
beta_m
=
4
ⅇ
V
18
d
d
time
m
=
alpha_m
1
-
m
-
beta_m
m
Component: sodium_channel_h_gate
alpha_h
=
0.07
ⅇ
V
20
beta_h
=
1
ⅇ
V
+
30
10
+
1
d
d
time
h
=
alpha_h
1
-
h
-
beta_h
h
Component: potassium_channel
E_K
=
E_R
+
12
i_K
=
g_K
n
4
V
-
E_K
Component: potassium_channel_n_gate
alpha_n
=
0.01
V
+
10
ⅇ
V
+
10
10
-
1
beta_n
=
0.125
ⅇ
V
80
d
d
time
n
=
alpha_n
1
-
n
-
beta_n
n
Component: leakage_current
E_L
=
E_R
-
10.613
i_L
=
g_L
V
-
E_L
Source
Derived from workspace
Hodgkin, Huxley, 1952
at changeset
32cbb0553667
.
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Creative Commons Attribution 3.0 Unported License
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A quantitative description of membrane current and its application to conductance and excitation in nerve
A quantitative description of membrane current and its application to conduction and excitation in nerve