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Tolic, Mosekilde, Sturis, 2000
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Modelling the Insulin-Glucose Feedback System: The Significance of Pulsatile Insulin Secretion
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Model Mathematics
Component based math viewer is available
Component: environment
Component: plasma_insulin
d
d
time
Ip
=
f1_G
-
E
Ip
Vp
-
Ii
Vi
+
Ip
tp
Ip_conc
=
Ip
Vp
f1_G
=
Rm
1
+
ⅇ
C1
-
G
Vg
a1
Component: intercellular_insulin
d
d
time
Ii
=
E
Ip
Vp
-
Ii
Vi
-
Ii
ti
Ii_conc
=
Ii
Vi
Component: glucose
d
d
time
G
=
Gin
+
f5_x3
+
-
f2_G
+
f3_G
f4_Ii
G_conc
=
G
Vg
10
f2_G
=
Ub
1
-
ⅇ
-
G
C2
Vg
f3_G
=
G
C3
Vg
f4_Ii
=
U0
+
Um
-
U0
1
+
ⅇ
-
beta
ln
Ii
C4
1
Vi
+
1
E
ti
f5_x3
=
Rg
1
+
ⅇ
alpha
x3
1
Vp
-
C5
Component: delay
d
d
time
x1
=
3
td
Ip
1
-
x1
d
d
time
x2
=
3
td
x1
-
x2
d
d
time
x3
=
3
td
x2
-
x3
Source
Derived from workspace
Tolic, Mosekilde, Sturis, 2000
at changeset
e3fea860d1d3
.
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Creative Commons Attribution 3.0 Unported License
.
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Modelling the Insulin-Glucose Feedback System: The Significance of Pulsatile Insulin Secretion