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C C There are a total of 11 entries in the algebraic variable array. C There are a total of 3 entries in each of the rate and state variable arrays. C There are a total of 21 entries in the constant variable array. C C C VOI is time in component environment (millisecond). C STATES(1) is V in component membrane (millivolt). C CONSTS(1) is C in component membrane (nanoF). C CONSTS(2) is i_app in component membrane (nanoA). C ALGBRC(11) is i_tonic_e in component tonic_current (nanoA). C ALGBRC(4) is i_Na in component fast_sodium_current (nanoA). C ALGBRC(9) is i_NaP in component persistent_sodium_current (nanoA). C ALGBRC(7) is i_K in component potassium_current (nanoA). C ALGBRC(10) is i_leak in component leakage_current (nanoA). C CONSTS(3) is E_Na in component fast_sodium_current (millivolt). C CONSTS(4) is g_Na in component fast_sodium_current (nanoS). C ALGBRC(1) is m_infinity in component fast_sodium_current_m_gate (dimensionless). C STATES(2) is n in component potassium_current_n_gate (dimensionless). C CONSTS(5) is theta_m in component fast_sodium_current_m_gate (millivolt). C CONSTS(6) is omega_m in component fast_sodium_current_m_gate (millivolt). C CONSTS(7) is g_K in component potassium_current (nanoS). C CONSTS(8) is E_K in component potassium_current (millivolt). C ALGBRC(2) is n_infinity in component potassium_current_n_gate (dimensionless). C ALGBRC(5) is tau_n in component potassium_current_n_gate (millisecond). C CONSTS(9) is tau_n_max in component potassium_current_n_gate (millisecond). C CONSTS(10) is theta_n in component potassium_current_n_gate (millivolt). C CONSTS(11) is omega_n in component potassium_current_n_gate (millivolt). C CONSTS(12) is g_NaP in component persistent_sodium_current (nanoS). C ALGBRC(8) is m_infinity in component persistent_sodium_current_m_gate (dimensionless). C STATES(3) is h in component persistent_sodium_current_h_gate (dimensionless). C CONSTS(13) is theta_m in component persistent_sodium_current_m_gate (millivolt). C CONSTS(14) is omega_m in component persistent_sodium_current_m_gate (millivolt). C ALGBRC(3) is h_infinity in component persistent_sodium_current_h_gate (dimensionless). C ALGBRC(6) is tau_h in component persistent_sodium_current_h_gate (millisecond). C CONSTS(15) is tau_h_max in component persistent_sodium_current_h_gate (millisecond). C CONSTS(16) is theta_h in component persistent_sodium_current_h_gate (millivolt). C CONSTS(17) is omega_h in component persistent_sodium_current_h_gate (millivolt). C CONSTS(18) is g_leak in component leakage_current (nanoS). C CONSTS(19) is E_leak in component leakage_current (millivolt). C CONSTS(20) is g_tonic_e in component tonic_current (nanoS). C CONSTS(21) is E_syn_e in component tonic_current (millivolt). C RATES(1) is d/dt V in component membrane (millivolt). C RATES(2) is d/dt n in component potassium_current_n_gate (dimensionless). C RATES(3) is d/dt h in component persistent_sodium_current_h_gate (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = -50.0 CONSTS(1) = 0.021 CONSTS(2) = 0 CONSTS(3) = 50 CONSTS(4) = 28 STATES(2) = 0.01 CONSTS(5) = -34 CONSTS(6) = -5 CONSTS(7) = 11.2 CONSTS(8) = -85 CONSTS(9) = 10 CONSTS(10) = -29 CONSTS(11) = -4 CONSTS(12) = 2.5 STATES(3) = 0.92 CONSTS(13) = -45.1 CONSTS(14) = -6 CONSTS(15) = 10000 CONSTS(16) = -53 CONSTS(17) = 6 CONSTS(18) = 2.2 CONSTS(19) = -57.5 CONSTS(20) = 0.2 CONSTS(21) = 0 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(10))/CONSTS(11))) ALGBRC(5) = CONSTS(9)/cosh((STATES(1) - CONSTS(10))/( 2.00000*CONSTS(11))) RATES(2) = (ALGBRC(2) - STATES(2))/ALGBRC(5) ALGBRC(3) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(16))/CONSTS(17))) ALGBRC(6) = CONSTS(15)/cosh((STATES(1) - CONSTS(16))/( 2.00000*CONSTS(17))) RATES(3) = (ALGBRC(3) - STATES(3))/ALGBRC(6) ALGBRC(11) = CONSTS(20)*(1.00000/1000.00)*(STATES(1) - CONSTS(21)) ALGBRC(1) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(5))/CONSTS(6))) ALGBRC(4) = CONSTS(4)*ALGBRC(1) ** 3.00000*(1.00000 - STATES(2))*(1.00000/1000.00)*(STATES(1) - CONSTS(3)) ALGBRC(8) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(13))/CONSTS(14))) ALGBRC(9) = CONSTS(12)*ALGBRC(8)*STATES(3)*(1.00000/1000.00)*(STATES(1) - CONSTS(3)) ALGBRC(7) = CONSTS(7)*STATES(2) ** 4.00000*(1.00000/1000.00)*(STATES(1) - CONSTS(8)) ALGBRC(10) = CONSTS(18)*(1.00000/1000.00)*(STATES(1) - CONSTS(19)) RATES(1) = (- (ALGBRC(4)+ALGBRC(9)+ALGBRC(7)+ALGBRC(10))+ALGBRC(11)+CONSTS(2))/CONSTS(1) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(10))/CONSTS(11))) ALGBRC(5) = CONSTS(9)/cosh((STATES(1) - CONSTS(10))/( 2.00000*CONSTS(11))) ALGBRC(3) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(16))/CONSTS(17))) ALGBRC(6) = CONSTS(15)/cosh((STATES(1) - CONSTS(16))/( 2.00000*CONSTS(17))) ALGBRC(11) = CONSTS(20)*(1.00000/1000.00)*(STATES(1) - CONSTS(21)) ALGBRC(1) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(5))/CONSTS(6))) ALGBRC(4) = CONSTS(4)*ALGBRC(1) ** 3.00000*(1.00000 - STATES(2))*(1.00000/1000.00)*(STATES(1) - CONSTS(3)) ALGBRC(8) = 1.00000/(1.00000+EXP((STATES(1) - CONSTS(13))/CONSTS(14))) ALGBRC(9) = CONSTS(12)*ALGBRC(8)*STATES(3)*(1.00000/1000.00)*(STATES(1) - CONSTS(3)) ALGBRC(7) = CONSTS(7)*STATES(2) ** 4.00000*(1.00000/1000.00)*(STATES(1) - CONSTS(8)) ALGBRC(10) = CONSTS(18)*(1.00000/1000.00)*(STATES(1) - CONSTS(19)) RETURN END