Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 21 entries in the algebraic variable array.
There are a total of 11 entries in each of the rate and state variable arrays.
There are a total of 22 entries in the constant variable array.
*/
/*
* VOI is time in component environment (ms).
* CONSTANTS[0] is R_gas_const in component parameters (millijoule_per_mole_kelvin).
* CONSTANTS[1] is Temp in component parameters (kelvin).
* CONSTANTS[2] is F in component parameters (coulomb_per_mole).
* STATES[0] is V in component membrane (mV).
* CONSTANTS[3] is Cm in component membrane (uF_per_cm2).
* ALGEBRAIC[0] is i_app in component stimulus_protocol (uA_per_cm2).
* ALGEBRAIC[18] is i_Na in component sodium_current (uA_per_cm2).
* ALGEBRAIC[3] is i_K in component potassium_current (uA_per_cm2).
* ALGEBRAIC[6] is i_leak in component leak_current (uA_per_cm2).
* CONSTANTS[4] is IstimStart in component stimulus_protocol (ms).
* CONSTANTS[5] is IstimEnd in component stimulus_protocol (ms).
* CONSTANTS[6] is IstimAmplitude in component stimulus_protocol (uA_per_cm2).
* CONSTANTS[7] is IstimPeriod in component stimulus_protocol (ms).
* CONSTANTS[8] is IstimPulseDuration in component stimulus_protocol (ms).
* ALGEBRAIC[16] is x_infinity in component sodium_current (dimensionless).
* ALGEBRAIC[1] is alpha_x in component sodium_current (dimensionless).
* ALGEBRAIC[2] is beta_x in component sodium_current (dimensionless).
* STATES[1] is n in component potassium_current_n_gate (dimensionless).
* ALGEBRAIC[4] is alpha_n in component potassium_current_n_gate (per_ms).
* ALGEBRAIC[5] is beta_n in component potassium_current_n_gate (per_ms).
* ALGEBRAIC[7] is T in component transmitter_release (uM).
* CONSTANTS[9] is T_bar in component transmitter_release (uM).
* STATES[2] is R in component transmitter_release (dimensionless).
* CONSTANTS[10] is kr_plus in component transmitter_release (per_uM_per_ms).
* CONSTANTS[11] is kr_minus in component transmitter_release (per_ms).
* ALGEBRAIC[20] is Ca in component calcium_concentration (uM).
* CONSTANTS[12] is Ca_ex in component calcium_concentration (uM).
* ALGEBRAIC[19] is Ca_open in component calcium_concentration (uM).
* CONSTANTS[13] is Dc in component calcium_concentration (um2_per_second).
* CONSTANTS[14] is r in component calcium_concentration (nm).
* ALGEBRAIC[17] is sigma in component calcium_concentration (uM_per_ms).
* ALGEBRAIC[8] is i_V in component calcium_concentration (uA).
* CONSTANTS[15] is g_Ca in component calcium_concentration (pS).
* CONSTANTS[16] is P in component calcium_concentration (mV_per_uM).
* ALGEBRAIC[14] is O in component O (dimensionless).
* ALGEBRAIC[9] is alpha in component rate_constants (per_ms).
* ALGEBRAIC[10] is alpha_ in component rate_constants (per_ms).
* ALGEBRAIC[11] is beta in component rate_constants (per_ms).
* ALGEBRAIC[12] is beta_ in component rate_constants (per_ms).
* ALGEBRAIC[13] is kG_plus in component rate_constants (per_ms).
* CONSTANTS[17] is kG_minus in component rate_constants (per_ms).
* CONSTANTS[18] is kG2_minus in component rate_constants (per_ms).
* CONSTANTS[19] is kG3_minus in component rate_constants (per_ms).
* STATES[3] is a in component rate_constants (dimensionless).
* CONSTANTS[20] is ka_plus in component rate_constants (per_uM_per_ms).
* CONSTANTS[21] is ka_minus in component rate_constants (per_ms).
* STATES[4] is C1 in component C1 (dimensionless).
* STATES[5] is C2 in component C2 (dimensionless).
* STATES[6] is C_G1 in component C_G1 (dimensionless).
* STATES[7] is C3 in component C3 (dimensionless).
* STATES[8] is C_G2 in component C_G2 (dimensionless).
* STATES[9] is C4 in component C4 (dimensionless).
* STATES[10] is C_G3 in component C_G3 (dimensionless).
* ALGEBRAIC[15] is C_G in component O (dimensionless).
* RATES[0] is d/dt V in component membrane (mV).
* RATES[1] is d/dt n in component potassium_current_n_gate (dimensionless).
* RATES[2] is d/dt R in component transmitter_release (dimensionless).
* RATES[3] is d/dt a in component rate_constants (dimensionless).
* RATES[4] is d/dt C1 in component C1 (dimensionless).
* RATES[5] is d/dt C2 in component C2 (dimensionless).
* RATES[7] is d/dt C3 in component C3 (dimensionless).
* RATES[9] is d/dt C4 in component C4 (dimensionless).
* RATES[6] is d/dt C_G1 in component C_G1 (dimensionless).
* RATES[8] is d/dt C_G2 in component C_G2 (dimensionless).
* RATES[10] is d/dt C_G3 in component C_G3 (dimensionless).
* There are a total of 3 condition variables.
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
CONSTANTS[0] = 8314.41;
CONSTANTS[1] = 310;
CONSTANTS[2] = 96485;
STATES[0] = -65;
CONSTANTS[3] = 1;
CONSTANTS[4] = 10;
CONSTANTS[5] = 50000;
CONSTANTS[6] = 40.0;
CONSTANTS[7] = 100;
CONSTANTS[8] = 1;
STATES[1] = 0;
CONSTANTS[9] = 4000.0;
STATES[2] = 0;
CONSTANTS[10] = 0.15;
CONSTANTS[11] = 2.5;
CONSTANTS[12] = 2000.0;
CONSTANTS[13] = 220;
CONSTANTS[14] = 10;
CONSTANTS[15] = 1.2;
CONSTANTS[16] = 0.006;
CONSTANTS[17] = 0.00025;
CONSTANTS[18] = 0.016;
CONSTANTS[19] = 1.024;
STATES[3] = 0;
CONSTANTS[20] = 200.0;
CONSTANTS[21] = 0.0015;
STATES[4] = 1;
STATES[5] = 0;
STATES[6] = 0;
STATES[7] = 0;
STATES[8] = 0;
STATES[9] = 0;
STATES[10] = 0;
RATES[0] = 0.1001;
RATES[1] = 0.1001;
RATES[2] = 0.1001;
RATES[3] = 0.1001;
RATES[4] = 0.1001;
RATES[5] = 0.1001;
RATES[7] = 0.1001;
RATES[9] = 0.1001;
RATES[6] = 0.1001;
RATES[8] = 0.1001;
RATES[10] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[0] - - ((ALGEBRAIC[18]+ALGEBRAIC[3]+ALGEBRAIC[6]) - ALGEBRAIC[0])/CONSTANTS[3];
resid[1] = RATES[1] - ALGEBRAIC[4]*(1.00000 - STATES[1]) - ALGEBRAIC[5]*STATES[1];
resid[2] = RATES[2] - CONSTANTS[10]*ALGEBRAIC[20]*(1.00000 - STATES[2]) - CONSTANTS[11]*STATES[2];
resid[3] = RATES[3] - CONSTANTS[20]*ALGEBRAIC[7]*(1.00000 - STATES[3]) - CONSTANTS[21]*STATES[3];
resid[4] = RATES[4] - ( ALGEBRAIC[11]*STATES[5]+ CONSTANTS[17]*STATES[6]) - STATES[4]*( 4.00000*ALGEBRAIC[9]+ALGEBRAIC[13]);
resid[5] = RATES[5] - ( 4.00000*ALGEBRAIC[9]*STATES[4]+ 2.00000*ALGEBRAIC[11]*STATES[7]+ CONSTANTS[18]*STATES[8]) - STATES[5]*(ALGEBRAIC[11]+ 3.00000*ALGEBRAIC[9]+ALGEBRAIC[13]);
resid[6] = RATES[7] - ( 3.00000*ALGEBRAIC[9]*STATES[5]+ 3.00000*ALGEBRAIC[11]*STATES[9]+ CONSTANTS[19]*STATES[10]) - STATES[7]*( 2.00000*ALGEBRAIC[11]+ 2.00000*ALGEBRAIC[9]+ALGEBRAIC[13]);
resid[7] = RATES[9] - ( 2.00000*ALGEBRAIC[9]*STATES[7]+ 4.00000*ALGEBRAIC[11]*ALGEBRAIC[14]) - STATES[9]*( 3.00000*ALGEBRAIC[11]+ALGEBRAIC[9]);
resid[8] = RATES[6] - ( ALGEBRAIC[12]*STATES[8]+ ALGEBRAIC[13]*STATES[4]) - STATES[6]*( 4.00000*ALGEBRAIC[10]+CONSTANTS[17]);
resid[9] = RATES[8] - ( 4.00000*ALGEBRAIC[10]*STATES[6]+ 2.00000*ALGEBRAIC[12]*STATES[10]+ ALGEBRAIC[13]*STATES[5]) - STATES[8]*(ALGEBRAIC[12]+ 3.00000*ALGEBRAIC[10]+CONSTANTS[18]);
resid[10] = RATES[10] - ( 3.00000*ALGEBRAIC[10]*STATES[8]+ ALGEBRAIC[13]*STATES[7]) - STATES[10]*( 2.00000*ALGEBRAIC[12]+CONSTANTS[19]);
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[15] = STATES[6]+STATES[8]+STATES[10];
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = (CONDVAR[0]>=0.00000&&CONDVAR[1]<=0.00000&&CONDVAR[2]<=0.00000 ? CONSTANTS[6] : 0.00000);
ALGEBRAIC[3] = ( 36.0000*pow(STATES[1], 4.00000)*(STATES[0]+77.0000))/1.00000;
ALGEBRAIC[4] = ( 0.0200000*(STATES[0]+55.0000))/(1.00000 - exp(- (STATES[0]+55.0000)/10.0000));
ALGEBRAIC[5] = 0.250000*exp(- (STATES[0]+65.0000)/80.0000);
ALGEBRAIC[6] = 0.300000*(STATES[0]+54.0000);
ALGEBRAIC[7] = CONSTANTS[9]*STATES[2];
ALGEBRAIC[9] = 0.450000*exp(STATES[0]/22.0000);
ALGEBRAIC[10] = ALGEBRAIC[9]/8.00000;
ALGEBRAIC[11] = 0.0150000*exp(- STATES[0]/14.0000);
ALGEBRAIC[12] = ALGEBRAIC[11]*8.00000;
ALGEBRAIC[13] = ( 3.00000*STATES[3])/(680.000+ 320.000*STATES[3]);
ALGEBRAIC[14] = ((((((1.00000 - STATES[4]) - STATES[5]) - STATES[7]) - STATES[9]) - STATES[6]) - STATES[8]) - STATES[10];
ALGEBRAIC[1] = ( 0.200000*(STATES[0]+40.0000))/(1.00000 - 1.00000*exp(- (STATES[0]+40.0000)/10.0000));
ALGEBRAIC[2] = 8.00000*exp(1.00000/- (STATES[0]+65.0000/18.0000));
ALGEBRAIC[16] = ALGEBRAIC[1]/(ALGEBRAIC[1]+ALGEBRAIC[2]);
ALGEBRAIC[18] = 120.000*pow(ALGEBRAIC[16], 3.00000)*(1.00000 - STATES[1])*(STATES[0] - 120.000);
ALGEBRAIC[8] = ( (( CONSTANTS[15]*CONSTANTS[16]*2.00000*CONSTANTS[2]*STATES[0])/( CONSTANTS[0]*CONSTANTS[1]))*CONSTANTS[12])/(1.00000 - exp(( 2.00000*CONSTANTS[2]*STATES[0])/( CONSTANTS[0]*CONSTANTS[1])));
ALGEBRAIC[17] = - 5.18200*ALGEBRAIC[8];
ALGEBRAIC[19] = ALGEBRAIC[17]/( 2.00000*CONSTANTS[13]*CONSTANTS[14]* 3.14159265358979);
ALGEBRAIC[20] = ALGEBRAIC[14]*ALGEBRAIC[19]+0.100000;
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
SI[8] = 1.0;
SI[9] = 1.0;
SI[10] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
CONDVAR[0] = VOI - CONSTANTS[4];
CONDVAR[1] = VOI - CONSTANTS[5];
CONDVAR[2] = ((VOI - CONSTANTS[4]) - floor((VOI - CONSTANTS[4])/CONSTANTS[7])*CONSTANTS[7]) - CONSTANTS[8];
}