Model Mathematics

Component: environment

Component: CycA

ddtimeCycA=k_dissaTri_A+V_diTri_A+V_sa-V_daCycA-k_assaCKICycA

Component: CycB

ddtimeCycB=V_sb-V_dbCycB+V_25pB-V_weeCycB-k_assbCycBCKI+k_dissbBCKI+V_diBCKI

Component: CycE

ddtimeCycE=k_disseTri_E+V_diTri_E+V_se-V_deCycE-k_asseCKICycE

Component: CycD

CycD=CycD_0mass

Component: Cdc20_A

ddtimeCdc20_A=k_a20APCPCdc20_iJ_a20+Cdc20_i-Cdc20_Ak_i20J_i20+Cdc20_A-Cdc20_Ak_d20

Component: Cdc20_i

ddtimeCdc20_i=k_s20p+k_s20ppCycBn20J_20n20+CycBn20+Cdc20_Ak_i20J_i20+Cdc20_A-k_d20Cdc20_i-k_a20APCPCdc20_iJ_a20+Cdc20_i

Component: APC

APC=APC_T-APCP1

Component: APCP

ddtimeAPCP=k_aieCycBAPCJ_aie+APC-k_iieAPCPJ_iie+APCP

Component: pB

ddtimepB=V_weeCycB-V_dbpB-k_assbpBCKI+k_dissbpBCKI+V_dipBCKI-V_25pB

Component: BCKI

ddtimeBCKI=k_assbCycBCKI-k_dissbBCKI+V_25pBCKI-V_weeBCKI-V_dbBCKI-V_diBCKI

Component: pBCKI

ddtimepBCKI=k_assbpBCKI-k_dissbpBCKI-V_25pBCKI+V_weeBCKI-V_dbpBCKI-V_dipBCKI

Component: Tri_A

ddtimeTri_A=k_assaCKICycA-k_dissaTri_A-V_diTri_A-V_daTri_A

Component: Tri_E

ddtimeTri_E=k_asseCKICycE-k_disseTri_E-V_diTri_E-V_deTri_E

Component: CKI

ddtimeCKI=-k_assbCycBCKI+k_dissbBCKI-k_assbpBCKI+k_dissbpBCKI+V_dbBCKI+V_dbpBCKI+V_si-V_diCKI-k_assaCKICycA+k_dissaTri_A+V_daTri_A-k_asseCKICycE+k_disseTri_E+V_deTri_E

Component: Cdh1_i

Cdh1_i=Cdh1_T-Cdh11

Component: Cdh1

ddtimeCdh1=Cdh1_iV_ah1J_ah1+Cdh1_i-Cdh1V_ih1J_ih1+Cdh1

Component: mass

ddtimemass=mumass1-massmaxmass

Component: V_atf

V_atf=k_atfp+k_atfappCycA+k_atfeppCycE+k_atfdppCycD

Component: V_itf

V_itf=k_itfp+k_itfappCycA+k_itfbppCycB

Component: TF_E

TF_E=2V_atfJ_itfV_itf-V_atf+J_atfV_itf+J_itfV_atf+V_itf-V_atf+J_atfV_itf+J_itfV_atf2-4V_itf-V_atfJ_itfV_atf

Component: V_de

V_de=k_dep+k_deeppCycE+k_deappCycA+k_debppCycB

Component: V_da

V_da=k_dap+k_dapp+k_dapppCdc20_A+k_dapppCdc20_i

Component: TF_I

Cdc14=Cdc20_A TF_I=2k_afiCdc14J_ifik_ifip+k_ifibppCycB-k_afiCdc14+J_afik_ifip+k_ifibppCycB+J_ifik_afiCdc14+k_ifip+k_ifibppCycB-k_afiCdc14+J_afik_ifip+k_ifibppCycB+J_ifik_afiCdc142-4k_ifip+k_ifibppCycB-k_afiCdc14J_ifik_afiCdc14

Component: V_ah1

V_ah1=k_ah1p+k_ah1ppCdc14

Component: V_ih1

V_ih1=k_ih1p+k_ih1appCycA+k_ih1bppCycB+k_ih1eppCycE+k_ih1dppCycD

Component: V_si

V_si=k_sip+k_sippTF_I

Component: V_di

V_di=k_dip+k_diappCycA+k_dibppCycB+k_dieppCycE+k_didppCycD1+k_14diCdc14

Component: preMPF

preMPF=pB+BCKI

Component: CycBT

CycBT=CycB+pB+BCKI+pBCKI

Component: CycAT

CycAT=CycA+Tri_A

Component: CycET

CycET=CycE+Tri_E

Component: Tri_B

Tri_B=BCKI+pBCKI

Component: CKIT

CKIT=CKI+BCKI+pBCKI+Tri_A+Tri_E

Component: Cdc20_T

Cdc20_T=Cdc20_i+Cdc20_A

Component: TF_B

TF_B=2k_afbCycBJ_ifbk_ifb-k_afbCycB+J_afbk_ifb+J_ifbk_afbCycB+k_ifb-k_afbCycB+J_afbk_ifb+J_ifbk_afbCycB2-4k_ifb-k_afbCycBk_afbCycBJ_ifb

Component: V_sb

V_sb=massk_sbp+k_sbppTF_B

Component: V_sa

V_sa=massk_sap+k_sappTF_E

Component: V_se

V_se=massk_sep+k_seppTF_E

Component: V_db

V_db=k_dbp+k_dbhppCdh1+k_dbcppCdc20_A

Component: Wee1

Wee1=2k_aweep+k_aweeppCdc14J_iweek_iweep+k_iweeppCycB-k_aweep+k_aweeppCdc14+J_aweek_iweep+k_iweeppCycB+J_iweek_aweep+k_aweeppCdc14+k_iweep+k_iweeppCycB-k_aweep+k_aweeppCdc14+J_aweek_iweep+k_iweeppCycB+J_iweek_aweep+k_aweeppCdc142-4k_iweep+k_iweeppCycB-k_aweep+k_aweeppCdc14k_aweep+k_aweeppCdc14J_iwee

Component: V_wee

V_wee=k_weep+k_weeppWee1

Component: Cdc25

Cdc25=2k_a25p+k_a25ppCycBJ_i25k_i25p+k_i25ppCdc14-k_a25p+k_a25ppCycB+J_a25k_i25p+k_i25ppCdc14+k_a25p+k_a25ppCycBJ_i25+k_i25p+k_i25ppCdc14-k_a25p+k_a25ppCycB+J_a25k_i25p+k_i25ppCdc14+k_a25p+k_a25ppCycBJ_i252-4k_i25p+k_i25ppCdc14-k_a25p+k_a25ppCycBk_a25p+k_a25ppCycBJ_i25

Component: V_25

V_25=k_25p+k_25ppCdc25

Component: kinetic_parameters