- Author:
- Matthias K?nig <matthias.koenig@charite.de>
- Date:
- 2013-05-17 20:14:36+02:00
- Desc:
- Further work on the HTML documentation.
- Permanent Source URI:
- https://models.cellml.org/w/matthiaskoenig/MetabolicComponentLibrary/rawfile/2ac29dd97e9204b8c5de02fa2ddf416afdd997e4/CellML-source/CellMLTools/models/BIOMD0000000070.sbml.xml
<?xml version='1.0' encoding='UTF-8' standalone='no'?>
<!-- This model was downloaded from BioModels Database -->
<!-- Thu Mar 21 03:22:08 GMT 2013 -->
<!-- http://www.ebi.ac.uk/biomodels/ -->
<sbml xmlns="http://www.sbml.org/sbml/level2" level="2" metaid="metaid_0000001" version="1">
<model id="Holzhutter2004_Erythrocyte_Metabolism" name="Holzhutter2004_Erythrocyte_Metabolism" metaid="metaid_0000002">
<notes>
<body xmlns="http://www.w3.org/1999/xhtml">
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="left"> <font face="Arial, Helvetica, sans-serif"> <b> <a href="http://www.sbml.org/">SBML</a>
level 2 code generated for the JWS Online project by Jacky Snoep using <a href="http://pysces.sourceforge.net/">PySCeS</a>
<br/>
Run this model online at <a href="http://jjj.biochem.sun.ac.za/">http://jjj.biochem.sun.ac.za</a>
<br/>
To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004) <a href="http://bioinformatics.oupjournals.org/cgi/content/abstract/20/13/2143">Web-based
modelling using JWS Online</a>
, Bioinformatics, 20:2143-2144 </b>
</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p align="right"> <font color="#FFFFFF">.</font>
</p>
<p> <u>Biomodels Curation</u>
The model simulates the flux values as given for "kinetic model" in Table 1 of the paper. The model was successfully tested on Jarnac. </p>
</body>
</notes>
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</vCard:N>
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<listOfParameters>
<parameter id="Vmaxv0" metaid="_846945" value="33.6" units="mM_per_hour"/>
<parameter id="KMoutv0" metaid="_846957" value="1.7" units="mM"/>
<parameter id="Keqv0" metaid="_846970" value="1" units="dimensionless"/>
<parameter id="KMinv0" metaid="_846982" value="6.9" units="mM"/>
<parameter id="alfav0" metaid="_846994" value="0.54" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vHEX" name="Hexokinase" metaid="metaid_0000050">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000050">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.7.1.2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00299"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1318"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Glcin" metaid="_847007"/>
<speciesReference species="MgATP" metaid="_847019"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Glc6P" metaid="_847031"/>
<speciesReference species="MgADP" metaid="_847043"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="Mgf" metaid="_847055"/>
<modifierSpeciesReference species="Gri23P2f" metaid="_847067"/>
<modifierSpeciesReference species="MgGri23P2" metaid="_847079"/>
</listOfModifiers>
<kineticLaw metaid="_847091">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci> Inhibv1 </ci>
<ci> Glcin </ci>
</apply>
<apply>
<plus/>
<ci> Glcin </ci>
<ci> KMGlcv1 </ci>
</apply>
</apply>
<apply>
<divide/>
<ci> Vmax1v1 </ci>
<ci> KMgATPv1 </ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<ci> MgATP </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmax2v1 </ci>
<ci> Vmax1v1 </ci>
</apply>
<ci> MgATP </ci>
<ci> Mgf </ci>
</apply>
<ci> KMgATPMgv1 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Glc6P </ci>
<ci> MgADP </ci>
</apply>
<ci> Keqv1 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<times/>
<apply>
<divide/>
<ci> MgATP </ci>
<ci> KMgATPv1 </ci>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Mgf </ci>
<ci> KMgATPMgv1 </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<ci> Mgf </ci>
<ci> KMgv1 </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn> 1.55 </cn>
<apply>
<divide/>
<ci> Glc6P </ci>
<ci> KGlc6Pv1 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Mgf </ci>
<ci> KMgv1 </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
<ci> K23P2Gv1 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Mgf </ci>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
</apply>
<apply>
<times/>
<ci> KMgv1 </ci>
<ci> KMg23P2Gv1 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Inhibv1" metaid="_847103" value="1" units="dimensionless"/>
<parameter id="KMGlcv1" metaid="_847115" value="0.1" units="mM"/>
<parameter id="Vmax1v1" metaid="_847127" value="15.8" units="mM_per_hour"/>
<parameter id="KMgATPv1" metaid="_847139" value="1.44" units="mM"/>
<parameter id="Vmax2v1" metaid="_847151" value="33.2" units="mM_per_hour"/>
<parameter id="KMgATPMgv1" metaid="_847163" value="1.14" units="mM"/>
<parameter id="Keqv1" metaid="_847176" value="3900" units="mM"/>
<parameter id="KMgv1" metaid="_847188" value="1.03" units="mM"/>
<parameter id="KGlc6Pv1" metaid="_847200" value="0.0045" units="mM"/>
<parameter id="K23P2Gv1" metaid="_847212" value="2.7" units="mM"/>
<parameter id="KMg23P2Gv1" metaid="_847224" value="3.44" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vGPI" name="Glucosephosphate isomerase" metaid="metaid_0000051">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000051">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/5.3.1.9"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00771"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1164"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Glc6P" metaid="_847236"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Fru6P" metaid="_847249"/>
</listOfProducts>
<kineticLaw metaid="_847261">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv2 </ci>
<apply>
<minus/>
<ci> Glc6P </ci>
<apply>
<divide/>
<ci> Fru6P </ci>
<ci> Keqv2 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> Glc6P </ci>
<apply>
<times/>
<ci> KGlc6Pv2 </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Fru6P </ci>
<ci> KFru6Pv2 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv2" metaid="_847273" value="935" units="mM_per_hour"/>
<parameter id="Keqv2" metaid="_847285" value="0.3925" units="dimensionless"/>
<parameter id="KGlc6Pv2" metaid="_847297" value="0.182" units="mM"/>
<parameter id="KFru6Pv2" metaid="_847309" value="0.071" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPFK" name="Phosphofructokinase" metaid="metaid_0000052">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000052">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.7.1.11"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00756"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_736"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="MgATP" metaid="_847321"/>
<speciesReference species="Fru6P" metaid="_847333"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Fru16P2" metaid="_847345"/>
<speciesReference species="MgADP" metaid="_847357"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="ATPf" metaid="_847369"/>
<modifierSpeciesReference species="Mgf" metaid="_847381"/>
<modifierSpeciesReference species="AMPf" metaid="_847393"/>
<modifierSpeciesReference species="MgAMP" metaid="_847406"/>
</listOfModifiers>
<kineticLaw metaid="_847418">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv3 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Fru6P </ci>
<ci> MgATP </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Fru16P2 </ci>
<ci> MgADP </ci>
</apply>
<ci> Keqv3 </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> Fru6P </ci>
<ci> KFru6Pv3 </ci>
</apply>
<apply>
<plus/>
<ci> MgATP </ci>
<ci> KMgATPv3 </ci>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<times/>
<ci> L0v3 </ci>
<apply>
<power/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> ATPf </ci>
<ci> KATPv3 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Mgf </ci>
<ci> KMgv3 </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<plus/>
<ci> AMPf </ci>
<ci> MgAMP </ci>
</apply>
<ci> KAMPv3 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Fru6P </ci>
<ci> KFru6Pv3 </ci>
</apply>
</apply>
</apply>
</apply>
<cn type="integer"> 4 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv3" metaid="_847430" value="239" units="mM_per_hour"/>
<parameter id="Keqv3" metaid="_847442" value="100000" units="dimensionless"/>
<parameter id="KFru6Pv3" metaid="_847454" value="0.1" units="mM"/>
<parameter id="KMgATPv3" metaid="_847466" value="0.068" units="mM"/>
<parameter id="L0v3" metaid="_847478" value="0.001072" units="dimensionless"/>
<parameter id="KATPv3" metaid="_847490" value="0.01" units="mM"/>
<parameter id="KMgv3" metaid="_847502" value="0.44" units="mM"/>
<parameter id="KAMPv3" metaid="_847514" value="0.033" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vALD" name="Aldolase" metaid="metaid_0000053">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000053">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/4.1.2.13"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01070"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1602"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Fru16P2" metaid="_847526"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GraP" metaid="_847538"/>
<speciesReference species="DHAP" metaid="_847550"/>
</listOfProducts>
<kineticLaw metaid="_847562">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmaxv4 </ci>
<ci> KFru16P2v4 </ci>
</apply>
<apply>
<minus/>
<ci> Fru16P2 </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> GraP </ci>
<ci> DHAP </ci>
</apply>
<ci> Keqv4 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Fru16P2 </ci>
<ci> KFru16P2v4 </ci>
</apply>
<apply>
<divide/>
<ci> GraP </ci>
<ci> KiGraPv4 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> DHAP </ci>
<apply>
<plus/>
<ci> GraP </ci>
<ci> KGraPv4 </ci>
</apply>
</apply>
<apply>
<times/>
<ci> KDHAPv4 </ci>
<ci> KiGraPv4 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Fru16P2 </ci>
<ci> GraP </ci>
</apply>
<apply>
<times/>
<ci> KFru16P2v4 </ci>
<ci> KiiGraPv4 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv4" metaid="_847574" value="98.91000366" units="mM_per_hour"/>
<parameter id="KFru16P2v4" metaid="_847586" value="0.0071" units="mM"/>
<parameter id="Keqv4" metaid="_847599" value="0.114" units="mM"/>
<parameter id="KiGraPv4" metaid="_847612" value="0.0572" units="mM"/>
<parameter id="KGraPv4" metaid="_847624" value="0.1906" units="mM"/>
<parameter id="KDHAPv4" metaid="_847636" value="0.0364" units="mM"/>
<parameter id="KiiGraPv4" metaid="_847648" value="0.176" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vTPI" name="Triosephosphate isomerase" metaid="metaid_0000054">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000054">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/5.3.1.1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01015"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_775"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="DHAP" metaid="_847660"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GraP" metaid="_847672"/>
</listOfProducts>
<kineticLaw metaid="_847685">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv5 </ci>
<apply>
<minus/>
<ci> DHAP </ci>
<apply>
<divide/>
<ci> GraP </ci>
<ci> Keqv5 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> DHAP </ci>
<apply>
<times/>
<ci> KDHAPv5 </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> GraP </ci>
<ci> KGraPv5 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv5" metaid="_847697" value="5456.600098" units="mM_per_hour"/>
<parameter id="Keqv5" metaid="_847709" value="0.0407" units="dimensionless"/>
<parameter id="KDHAPv5" metaid="_847721" value="0.838" units="mM"/>
<parameter id="KGraPv5" metaid="_847733" value="0.428" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vGAPDH" name="Glyceraldehyde 3-phosphate dehydrogenase" metaid="metaid_0000055">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000055">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01061"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1847"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.2.1.12"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="GraP" metaid="_847745"/>
<speciesReference species="Phi" metaid="_847757"/>
<speciesReference species="NAD" metaid="_847770"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="NADH" metaid="_847782"/>
<speciesReference species="Gri13P2" metaid="_847794"/>
</listOfProducts>
<kineticLaw metaid="_847806">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmaxv6 </ci>
<apply>
<times/>
<ci> KNADv6 </ci>
<ci> KGraPv6 </ci>
<ci> KPv6 </ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> NAD </ci>
<ci> GraP </ci>
<ci> Phi </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Gri13P2 </ci>
<ci> NADH </ci>
</apply>
<ci> Keqv6 </ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> NAD </ci>
<ci> KNADv6 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> GraP </ci>
<ci> KGraPv6 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Phi </ci>
<ci> KPv6 </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> NADH </ci>
<ci> KNADHv6 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Gri13P2 </ci>
<ci> K13P2Gv6 </ci>
</apply>
</apply>
</apply>
</apply>
<cn type="integer"> 1 </cn>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv6" metaid="_847818" value="4300" units="mM_per_hour"/>
<parameter id="KNADv6" metaid="_847830" value="0.05" units="mM"/>
<parameter id="KGraPv6" metaid="_847842" value="0.005" units="mM"/>
<parameter id="KPv6" metaid="_847854" value="3.9" units="mM"/>
<parameter id="Keqv6" metaid="_847866" value="0.000192" units="dimensionless"/>
<parameter id="KNADHv6" metaid="_847879" value="0.0083" units="mM"/>
<parameter id="K13P2Gv6" metaid="_847891" value="0.0035" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPGK" name="Phosphoglycerate kinase" metaid="metaid_0000056">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000056">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01512"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1186"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.7.2.3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="MgADP" metaid="_847904"/>
<speciesReference species="Gri13P2" metaid="_847916"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="MgATP" metaid="_847928"/>
<speciesReference species="Gri3P" metaid="_847940"/>
</listOfProducts>
<kineticLaw metaid="_847952">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmaxv7 </ci>
<apply>
<times/>
<ci> KMgADPv7 </ci>
<ci> K13P2Gv7 </ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> MgADP </ci>
<ci> Gri13P2 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> MgATP </ci>
<ci> Gri3P </ci>
</apply>
<ci> Keqv7 </ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> MgADP </ci>
<ci> KMgADPv7 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Gri13P2 </ci>
<ci> K13P2Gv7 </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> MgATP </ci>
<ci> KMgATPv7 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Gri3P </ci>
<ci> K3PGv7 </ci>
</apply>
</apply>
</apply>
</apply>
<cn type="integer"> 1 </cn>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv7" metaid="_847964" value="5000" units="mM_per_hour"/>
<parameter id="KMgADPv7" metaid="_847976" value="0.35" units="mM"/>
<parameter id="K13P2Gv7" metaid="_847988" value="0.002" units="mM"/>
<parameter id="Keqv7" metaid="_848000" value="1455" units="dimensionless"/>
<parameter id="KMgATPv7" metaid="_848013" value="0.48" units="mM"/>
<parameter id="K3PGv7" metaid="_848025" value="1.2" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vBPGM" name="Bisphosphoglycerate mutase" metaid="metaid_0000057">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000057">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/5.4.2.4"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01662"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Gri13P2" metaid="_848037"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Gri23P2f" metaid="_848049"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="MgGri23P2" metaid="_848061"/>
</listOfModifiers>
<kineticLaw metaid="_848073">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> kDPGMv8 </ci>
<apply>
<minus/>
<ci> Gri13P2 </ci>
<apply>
<divide/>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
<ci> Keqv8 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
<ci> K23P2Gv8 </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="kDPGMv8" metaid="_848085" value="76000" units="hour_inverse"/>
<parameter id="Keqv8" metaid="_848097" value="100000" units="dimensionless"/>
<parameter id="K23P2Gv8" metaid="_848109" value="0.04" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vBPGP" name="Bisphosphoglycerate phosphatase" metaid="metaid_0000058">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000058">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01516"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/3.1.3.13"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Gri23P2f" metaid="_848121"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Gri3P" metaid="_848133"/>
<speciesReference species="Phi" metaid="_848145"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="MgGri23P2" metaid="_848158"/>
</listOfModifiers>
<kineticLaw metaid="_848170">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv9 </ci>
<apply>
<minus/>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
<apply>
<divide/>
<ci> Gri3P </ci>
<ci> Keqv9 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
<ci> K23P2Gv9 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv9" metaid="_848182" value="0.53" units="mM_per_hour"/>
<parameter id="Keqv9" metaid="_848194" value="100000" units="dimensionless"/>
<parameter id="K23P2Gv9" metaid="_848206" value="0.2" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPGM" name="Phosphoglycerate mutase" metaid="metaid_0000059">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000059">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/5.4.2.1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01518"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_576"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Gri3P" metaid="_848218"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Gri2P" metaid="_848230"/>
</listOfProducts>
<kineticLaw metaid="_848243">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv10 </ci>
<apply>
<minus/>
<ci> Gri3P </ci>
<apply>
<divide/>
<ci> Gri2P </ci>
<ci> Keqv10 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> Gri3P </ci>
<apply>
<times/>
<ci> K3PGv10 </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Gri2P </ci>
<ci> K2PGv10 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv10" metaid="_848256" value="2000" units="mM_per_hour"/>
<parameter id="Keqv10" metaid="_848268" value="0.145" units="dimensionless"/>
<parameter id="K3PGv10" metaid="_848280" value="5" units="mM"/>
<parameter id="K2PGv10" metaid="_848293" value="1" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vENO" name="Enolase" metaid="metaid_0000060">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000060">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/4.2.1.11"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00658"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1400"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Gri2P" metaid="_848305"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="PEP" metaid="_848317"/>
</listOfProducts>
<kineticLaw metaid="_848329">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv11 </ci>
<apply>
<minus/>
<ci> Gri2P </ci>
<apply>
<divide/>
<ci> PEP </ci>
<ci> Keqv11 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> Gri2P </ci>
<apply>
<times/>
<ci> K2PGv11 </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> KPEPv11 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv11" metaid="_848342" value="1500" units="mM_per_hour"/>
<parameter id="Keqv11" metaid="_848354" value="1.7" units="dimensionless"/>
<parameter id="K2PGv11" metaid="_848366" value="1" units="mM"/>
<parameter id="KPEPv11" metaid="_848378" value="1" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPK" name="Pyruvate kinase" metaid="metaid_0000061">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000061">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00200"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1911"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.7.1.40"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="PEP" metaid="_848390"/>
<speciesReference species="MgADP" metaid="_848402"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="MgATP" metaid="_848414"/>
<speciesReference species="Pyr" metaid="_848426"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="ATPf" metaid="_848438"/>
<modifierSpeciesReference species="Fru16P2" metaid="_848450"/>
</listOfModifiers>
<kineticLaw metaid="_848463">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv12 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> PEP </ci>
<ci> MgADP </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Pyr </ci>
<ci> MgATP </ci>
</apply>
<ci> Keqv12 </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> PEP </ci>
<ci> KPEPv12 </ci>
</apply>
<apply>
<plus/>
<ci> MgADP </ci>
<ci> KMgADPv12 </ci>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> L0v12 </ci>
<apply>
<power/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<plus/>
<ci> ATPf </ci>
<ci> MgATP </ci>
</apply>
<ci> KATPv12 </ci>
</apply>
</apply>
<cn type="integer"> 4 </cn>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> PEP </ci>
<ci> KPEPv12 </ci>
</apply>
</apply>
<cn type="integer"> 4 </cn>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Fru16P2 </ci>
<ci> KFru16P2v12 </ci>
</apply>
</apply>
<cn type="integer"> 4 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv12" metaid="_848475" value="570" units="mM_per_hour"/>
<parameter id="Keqv12" metaid="_848487" value="13790" units="dimensionless"/>
<parameter id="KPEPv12" metaid="_848499" value="0.225" units="mM"/>
<parameter id="KMgADPv12" metaid="_848511" value="0.474" units="mM"/>
<parameter id="L0v12" metaid="_848523" value="19" units="dimensionless"/>
<parameter id="KATPv12" metaid="_848535" value="3.39" units="mM"/>
<parameter id="KFru16P2v12" metaid="_848547" value="0.005" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vLDHNADH" name="Lactate dehydrogenase" metaid="metaid_0000062">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000062">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00703"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_178"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.1.1.27"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="NADH" metaid="_848559"/>
<speciesReference species="Pyr" metaid="_848571"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Lac" metaid="_848583"/>
<speciesReference species="NAD" metaid="_848596"/>
</listOfProducts>
<kineticLaw metaid="_848608">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> Vmaxv13 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Pyr </ci>
<ci> NADH </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Lac </ci>
<ci> NAD </ci>
</apply>
<ci> Keqv13 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv13" metaid="_848620" value="2800000" units="per_mM_hour"/>
<parameter id="Keqv13" metaid="_848632" value="9090" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vLDHNADPH" name="Lactate dehydrogenase" metaid="metaid_0000063">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000063">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.1.1.27"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Pyr" metaid="_848644"/>
<speciesReference species="NADPHf" metaid="_848656"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Lac" metaid="_848668"/>
<speciesReference species="NADPf" metaid="_848680"/>
</listOfProducts>
<kineticLaw metaid="_848692">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> kLDHv14 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Pyr </ci>
<ci> NADPHf </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Lac </ci>
<ci> NADPf </ci>
</apply>
<ci> Keqv14 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="kLDHv14" metaid="_848704" value="243.4" units="per_mM_hour"/>
<parameter id="Keqv14" metaid="_848716" value="1.41818E4" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vATPase" name="ATPase" metaid="metaid_0000064">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000064">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00086"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/3.6.1.3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="MgATP" metaid="_848728"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Phi" metaid="_848740"/>
<speciesReference species="MgADP" metaid="_848752"/>
</listOfProducts>
<kineticLaw metaid="_848764">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> kATPasev15 </ci>
<ci> MgATP </ci>
</apply>
</math>
<listOfParameters>
<parameter id="kATPasev15" metaid="_848776" value="1.68" units="hour_inverse"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vAK" name="Adenylate kinase" metaid="metaid_0000065">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000065">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.7.4.3"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00127"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="MgATP" metaid="_848788"/>
<speciesReference species="AMPf" metaid="_848800"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="ADPf" metaid="_848812"/>
<speciesReference species="MgADP" metaid="_848824"/>
</listOfProducts>
<kineticLaw metaid="_848836">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<ci> Vmaxv16 </ci>
<apply>
<times/>
<ci> KATPv16 </ci>
<ci> KAMPv16 </ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> MgATP </ci>
<ci> AMPf </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> MgADP </ci>
<ci> ADPf </ci>
</apply>
<ci> Keqv16 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> MgATP </ci>
<ci> KATPv16 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> AMPf </ci>
<ci> KAMPv16 </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<ci> MgADP </ci>
<ci> ADPf </ci>
</apply>
<ci> KADPv16 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> MgADP </ci>
<ci> ADPf </ci>
</apply>
<apply>
<power/>
<ci> KADPv16 </ci>
<cn type="integer"> 2 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv16" metaid="_848848" value="1380" units="mM_per_hour"/>
<parameter id="KATPv16" metaid="_848860" value="0.09" units="mM"/>
<parameter id="KAMPv16" metaid="_848872" value="0.08" units="mM"/>
<parameter id="Keqv16" metaid="_848884" value="0.25" units="dimensionless"/>
<parameter id="KADPv16" metaid="_848896" value="0.11" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vG6PDH" name="Glucose 6-phosphate dehydrogenase" metaid="metaid_0000066">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000066">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.1.1.49"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:hasVersion>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1868"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1125"/>
</rdf:Bag>
</bqbiol:hasVersion>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00835"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Glc6P" metaid="_848908"/>
<speciesReference species="NADPf" metaid="_848920"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GlcA6P" metaid="_848932"/>
<speciesReference species="NADPHf" metaid="_848944"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="ATPf" metaid="_848956"/>
<modifierSpeciesReference species="MgATP" metaid="_848968"/>
<modifierSpeciesReference species="Gri23P2f" metaid="_848981"/>
<modifierSpeciesReference species="MgGri23P2" metaid="_848993"/>
</listOfModifiers>
<kineticLaw metaid="_849005">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<divide/>
<ci> Vmaxv17 </ci>
<ci> KG6Pv17 </ci>
</apply>
<ci> KNADPv17 </ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> Glc6P </ci>
<ci> NADPf </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> GlcA6P </ci>
<ci> NADPHf </ci>
</apply>
<ci> Keqv17 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> NADPf </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Glc6P </ci>
<ci> KG6Pv17 </ci>
</apply>
</apply>
</apply>
<ci> KNADPv17 </ci>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<ci> ATPf </ci>
<ci> MgATP </ci>
</apply>
<ci> KATPv17 </ci>
</apply>
<apply>
<divide/>
<ci> NADPHf </ci>
<ci> KNADPHv17 </ci>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
<ci> KPGA23v17 </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv17" metaid="_849017" value="162" units="mM_per_hour"/>
<parameter id="KG6Pv17" metaid="_849029" value="0.0667" units="mM"/>
<parameter id="KNADPv17" metaid="_849041" value="0.00367" units="mM"/>
<parameter id="Keqv17" metaid="_849053" value="2000" units="dimensionless"/>
<parameter id="KATPv17" metaid="_849065" value="0.749" units="mM"/>
<parameter id="KNADPHv17" metaid="_849077" value="0.00312" units="mM"/>
<parameter id="KPGA23v17" metaid="_849089" value="2.289" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPGLDH" name="Phosphogluconate dehydrogenase" metaid="metaid_0000067">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000067">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.1.1.44"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:hasPart>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R02035"/>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01528"/>
</rdf:Bag>
</bqbiol:hasPart>
<bqbiol:hasPart>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_2072"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_611"/>
</rdf:Bag>
</bqbiol:hasPart>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="GlcA6P" metaid="_849101"/>
<speciesReference species="NADPf" metaid="_849114"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Rul5P" metaid="_849126"/>
<speciesReference species="NADPHf" metaid="_849138"/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference species="Gri23P2f" metaid="_849150"/>
<modifierSpeciesReference species="MgGri23P2" metaid="_849162"/>
<modifierSpeciesReference species="ATPf" metaid="_849174"/>
<modifierSpeciesReference species="MgATP" metaid="_849186"/>
</listOfModifiers>
<kineticLaw metaid="_849198">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<divide/>
<ci> Vmaxv18 </ci>
<ci> K6PG1v18 </ci>
</apply>
<ci> KNADPv18 </ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci> GlcA6P </ci>
<ci> NADPf </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> Rul5P </ci>
<ci> NADPHf </ci>
</apply>
<ci> Keqv18 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> NADPf </ci>
<ci> KNADPv18 </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> GlcA6P </ci>
<ci> K6PG1v18 </ci>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<ci> Gri23P2f </ci>
<ci> MgGri23P2 </ci>
</apply>
<ci> KPGA23v18 </ci>
</apply>
</apply>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<ci> ATPf </ci>
<ci> MgATP </ci>
</apply>
<ci> KATPv18 </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> NADPHf </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> GlcA6P </ci>
<ci> K6PG2v18 </ci>
</apply>
</apply>
</apply>
<ci> KNADPHv18 </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv18" metaid="_849210" value="1575" units="mM_per_hour"/>
<parameter id="K6PG1v18" metaid="_849222" value="0.01" units="mM"/>
<parameter id="KNADPv18" metaid="_849234" value="0.018" units="mM"/>
<parameter id="Keqv18" metaid="_849246" value="141.7" units="dimensionless"/>
<parameter id="KPGA23v18" metaid="_849258" value="0.12" units="mM"/>
<parameter id="KATPv18" metaid="_849270" value="0.154" units="mM"/>
<parameter id="K6PG2v18" metaid="_849282" value="0.058" units="mM"/>
<parameter id="KNADPHv18" metaid="_849294" value="0.0045" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vGSSGRD" name="Glutathione reductase" metaid="metaid_0000068">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000068">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R00094"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_2220"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.8.1.7"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="GSSG" metaid="_849306"/>
<speciesReference species="NADPHf" metaid="_849318"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GSH" metaid="_849330" stoichiometry="2"/>
<speciesReference species="NADPf" metaid="_849342"/>
</listOfProducts>
<kineticLaw metaid="_849354">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv19 </ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci> GSSG </ci>
<ci> NADPHf </ci>
</apply>
<apply>
<times/>
<ci> KGSSGv19 </ci>
<ci> KNADPHv19 </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<power/>
<ci> GSH </ci>
<cn type="integer"> 2 </cn>
</apply>
<apply>
<power/>
<ci> KGSHv19 </ci>
<cn type="integer"> 2 </cn>
</apply>
</apply>
<ci> NADPf </ci>
</apply>
<apply>
<times/>
<ci> KNADPv19 </ci>
<ci> Keqv19 </ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> NADPHf </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> GSSG </ci>
<ci> KGSSGv19 </ci>
</apply>
</apply>
</apply>
<ci> KNADPHv19 </ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci> NADPf </ci>
<ci> KNADPv19 </ci>
</apply>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> GSH </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> GSH </ci>
<ci> KGSHv19 </ci>
</apply>
</apply>
</apply>
<ci> KGSHv19 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv19" metaid="_849367" value="90" units="mM_per_hour"/>
<parameter id="KGSSGv19" metaid="_849379" value="0.0652" units="mM"/>
<parameter id="KNADPHv19" metaid="_849391" value="0.00852" units="mM"/>
<parameter id="KGSHv19" metaid="_849403" value="20" units="mM"/>
<parameter id="KNADPv19" metaid="_849415" value="0.07" units="mM"/>
<parameter id="Keqv19" metaid="_849427" value="1.04" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vGSHox" name="Glutathione oxidation" metaid="metaid_0000069">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000069">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/1.8.1.7"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqmodel:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_2037"/>
</rdf:Bag>
</bqmodel:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="GSH" metaid="_849439" stoichiometry="2"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GSSG" metaid="_849451"/>
</listOfProducts>
<kineticLaw metaid="_849463">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> Kv20 </ci>
<ci> GSH </ci>
</apply>
</math>
<listOfParameters>
<parameter id="Kv20" metaid="_849476" value="0.03" units="hour_inverse"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vRibPepi" name="Phosphoribulose epimerase" metaid="metaid_0000070">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000070">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01529"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1522"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/5.1.3.1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Rul5P" metaid="_849488"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Xul5P" metaid="_849500"/>
</listOfProducts>
<kineticLaw metaid="_849512">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv21 </ci>
<apply>
<minus/>
<ci> Rul5P </ci>
<apply>
<divide/>
<ci> Xul5P </ci>
<ci> Keqv21 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> Rul5P </ci>
<apply>
<times/>
<ci> KRu5Pv21 </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Xul5P </ci>
<ci> KX5Pv21 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv21" metaid="_849524" value="4634" units="mM_per_hour"/>
<parameter id="Keqv21" metaid="_849536" value="2.7" units="dimensionless"/>
<parameter id="KRu5Pv21" metaid="_849548" value="0.19" units="mM"/>
<parameter id="KX5Pv21" metaid="_849560" value="0.5" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vRibPiso" name="Ribose phosphate isomerase" metaid="metaid_0000071">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000071">
<bqmodel:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/5.3.1.6"/>
</rdf:Bag>
</bqmodel:is>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01056"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_2033"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Rul5P" metaid="_849572"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Rib5P" metaid="_849584"/>
</listOfProducts>
<kineticLaw metaid="_849596">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv22 </ci>
<apply>
<minus/>
<ci> Rul5P </ci>
<apply>
<divide/>
<ci> Rib5P </ci>
<ci> Keqv22 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> Rul5P </ci>
<apply>
<times/>
<ci> KRu5Pv22 </ci>
<apply>
<plus/>
<cn type="integer"> 1 </cn>
<apply>
<divide/>
<ci> Rib5P </ci>
<ci> KR5Pv22 </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv22" metaid="_849608" value="730" units="mM_per_hour"/>
<parameter id="Keqv22" metaid="_849620" value="3" units="dimensionless"/>
<parameter id="KRu5Pv22" metaid="_849632" value="0.78" units="mM"/>
<parameter id="KR5Pv22" metaid="_849644" value="2.2" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vTrKet1" name="Transketolase 1" metaid="metaid_0000072">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000072">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.2.1.1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01641"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1629"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Xul5P" metaid="_849657"/>
<speciesReference species="Rib5P" metaid="_849669"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GraP" metaid="_849681"/>
<speciesReference species="Sed7P" metaid="_849693"/>
</listOfProducts>
<kineticLaw metaid="_849705">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv23 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Rib5P </ci>
<ci> Xul5P </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> GraP </ci>
<ci> Sed7P </ci>
</apply>
<ci> Keqv23 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<ci> K1v23 </ci>
<ci> Rib5P </ci>
</apply>
<ci> Xul5P </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> K2v23 </ci>
<apply>
<times/>
<ci> K6v23 </ci>
<ci> Sed7P </ci>
</apply>
</apply>
<ci> Rib5P </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> K3v23 </ci>
<apply>
<times/>
<ci> K5v23 </ci>
<ci> Sed7P </ci>
</apply>
</apply>
<ci> GraP </ci>
</apply>
<apply>
<times/>
<ci> K4v23 </ci>
<ci> Sed7P </ci>
</apply>
<apply>
<times/>
<ci> K7v23 </ci>
<ci> Xul5P </ci>
<ci> GraP </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv23" metaid="_849717" value="23.5" units="mM_per_hour"/>
<parameter id="Keqv23" metaid="_849729" value="1.05" units="dimensionless"/>
<parameter id="K1v23" metaid="_849741" value="0.4177" units="mM"/>
<parameter id="K2v23" metaid="_849753" value="0.3055" units="mM"/>
<parameter id="K6v23" metaid="_849765" value="0.00774" units="dimensionless"/>
<parameter id="K3v23" metaid="_849777" value="12.432" units="mM"/>
<parameter id="K5v23" metaid="_849789" value="0.41139" units="dimensionless"/>
<parameter id="K4v23" metaid="_849801" value="0.00496" units="mM"/>
<parameter id="K7v23" metaid="_849813" value="48.8" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vTrAld" name="Transaldolase" metaid="metaid_0000073">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000073">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.2.1.2"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01827"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_479"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="GraP" metaid="_849825"/>
<speciesReference species="Sed7P" metaid="_849837"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="E4P" metaid="_849849"/>
<speciesReference species="Fru6P" metaid="_849861"/>
</listOfProducts>
<kineticLaw metaid="_849873">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv24 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Sed7P </ci>
<ci> GraP </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> E4P </ci>
<ci> Fru6P </ci>
</apply>
<ci> Keqv24 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<ci> K1v24 </ci>
<ci> GraP </ci>
</apply>
<ci> Sed7P </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> K2v24 </ci>
<apply>
<times/>
<ci> K6v24 </ci>
<ci> Fru6P </ci>
</apply>
</apply>
<ci> GraP </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> K3v24 </ci>
<apply>
<times/>
<ci> K5v24 </ci>
<ci> Fru6P </ci>
</apply>
</apply>
<ci> E4P </ci>
</apply>
<apply>
<times/>
<ci> K4v24 </ci>
<ci> Fru6P </ci>
</apply>
<apply>
<times/>
<ci> K7v24 </ci>
<ci> Sed7P </ci>
<ci> E4P </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv24" metaid="_849885" value="27.2" units="mM_per_hour"/>
<parameter id="Keqv24" metaid="_849897" value="1.05" units="dimensionless"/>
<parameter id="K1v24" metaid="_849909" value="0.00823" units="mM"/>
<parameter id="K2v24" metaid="_849921" value="0.04765" units="mM"/>
<parameter id="K6v24" metaid="_849933" value="0.4653" units="dimensionless"/>
<parameter id="K3v24" metaid="_849945" value="0.1733" units="mM"/>
<parameter id="K5v24" metaid="_849957" value="0.8683" units="dimensionless"/>
<parameter id="K4v24" metaid="_849969" value="0.006095" units="mM"/>
<parameter id="K7v24" metaid="_849981" value="2.524" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPPRPPS" name="Phosphoribosylpyrophosphate synthetase" metaid="metaid_0000074">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000074">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.7.6.1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01049"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_2023"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="MgATP" metaid="_849993"/>
<speciesReference species="Rib5P" metaid="_850005"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="MgAMP" metaid="_850017"/>
<speciesReference species="PRPP" metaid="_850030"/>
</listOfProducts>
<kineticLaw metaid="_850043">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv25 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> Rib5P </ci>
<ci> MgATP </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> PRPP </ci>
<ci> MgAMP </ci>
</apply>
<ci> Keqv25 </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> KATPv25 </ci>
<ci> MgATP </ci>
</apply>
<apply>
<plus/>
<ci> KR5Pv25 </ci>
<ci> Rib5P </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv25" metaid="_850055" value="1.1" units="mM_per_hour"/>
<parameter id="Keqv25" metaid="_850067" value="100000" units="dimensionless"/>
<parameter id="KATPv25" metaid="_850079" value="0.03" units="mM"/>
<parameter id="KR5Pv25" metaid="_850091" value="0.57" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vTrKet2" name="Transketolase 2" metaid="metaid_0000075">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000075">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/kegg.reaction/R01830"/>
<rdf:li rdf:resource="http://identifiers.org/reactome/REACT_1811"/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/ec-code/2.2.1.1"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Xul5P" metaid="_850103"/>
<speciesReference species="E4P" metaid="_850115"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="GraP" metaid="_850127"/>
<speciesReference species="Fru6P" metaid="_850139"/>
</listOfProducts>
<kineticLaw metaid="_850151">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Vmaxv26 </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> E4P </ci>
<ci> Xul5P </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> GraP </ci>
<ci> Fru6P </ci>
</apply>
<ci> Keqv26 </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<plus/>
<ci> K1v26 </ci>
<ci> E4P </ci>
</apply>
<ci> Xul5P </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> K2v26 </ci>
<apply>
<times/>
<ci> K6v26 </ci>
<ci> Fru6P </ci>
</apply>
</apply>
<ci> E4P </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> K3v26 </ci>
<apply>
<times/>
<ci> K5v26 </ci>
<ci> Fru6P </ci>
</apply>
</apply>
<ci> GraP </ci>
</apply>
<apply>
<times/>
<ci> K4v26 </ci>
<ci> Fru6P </ci>
</apply>
<apply>
<times/>
<ci> K7v26 </ci>
<ci> Xul5P </ci>
<ci> GraP </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv26" metaid="_850163" value="23.5" units="mM_per_hour"/>
<parameter id="Keqv26" metaid="_850176" value="1.2" units="dimensionless"/>
<parameter id="K1v26" metaid="_850188" value="0.00184" units="mM"/>
<parameter id="K2v26" metaid="_850200" value="0.3055" units="mM"/>
<parameter id="K6v26" metaid="_850212" value="0.122" units="dimensionless"/>
<parameter id="K3v26" metaid="_850224" value="0.0548" units="mM"/>
<parameter id="K5v26" metaid="_850237" value="0.0287" units="dimensionless"/>
<parameter id="K4v26" metaid="_850249" value="0.0003" units="mM"/>
<parameter id="K7v26" metaid="_850261" value="0.215" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPhiexch" name="Phosphate exchange" metaid="metaid_0000076">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000076">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0009935"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Phiex" metaid="_850273"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Phi" metaid="_850285"/>
</listOfProducts>
<kineticLaw metaid="_850297">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> Vmaxv27 </ci>
<apply>
<minus/>
<ci> Phiex </ci>
<apply>
<divide/>
<ci> Phi </ci>
<ci> Keqv27 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv27" metaid="_850309" value="100" units="hour_inverse"/>
<parameter id="Keqv27" metaid="_850321" value="1" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vLacexch" name="Lactate exchange" metaid="metaid_0000077">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000077">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0009935"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Lacex" metaid="_850333"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Lac" metaid="_850345"/>
</listOfProducts>
<kineticLaw metaid="_850357">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> Vmaxv28 </ci>
<apply>
<minus/>
<ci> Lacex </ci>
<apply>
<divide/>
<ci> Lac </ci>
<ci> Keqv28 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv28" metaid="_850369" value="10000" units="hour_inverse"/>
<parameter id="Keqv28" metaid="_850381" value="1" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vPyrexch" name="Pyruvate exchange" metaid="metaid_0000078">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000078">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0009935"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="Pyrex" metaid="_850393"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Pyr" metaid="_850405"/>
</listOfProducts>
<kineticLaw metaid="_850417">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> Vmaxv29 </ci>
<apply>
<minus/>
<ci> Pyrex </ci>
<apply>
<divide/>
<ci> Pyr </ci>
<ci> Keqv29 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="Vmaxv29" metaid="_850429" value="10000" units="hour_inverse"/>
<parameter id="Keqv29" metaid="_850441" value="1" units="dimensionless"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vMgATP" name="MgATP dissociation" metaid="metaid_0000079">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000079">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0006754"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="MgATP" metaid="_850453"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Mgf" metaid="_850465"/>
<speciesReference species="ATPf" metaid="_850477"/>
</listOfProducts>
<kineticLaw metaid="_850489">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> MgATP </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Mgf </ci>
<ci> ATPf </ci>
</apply>
<ci> KdATP </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850501" value="10000000" units="hour_inverse"/>
<parameter id="KdATP" metaid="_850513" value="0.072" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vMgADP" name="MgADP dissociation" metaid="metaid_0000080">
<listOfReactants>
<speciesReference species="MgADP" metaid="_850525"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Mgf" metaid="_850537"/>
<speciesReference species="ADPf" metaid="_850549"/>
</listOfProducts>
<kineticLaw metaid="_850561">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> MgADP </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Mgf </ci>
<ci> ADPf </ci>
</apply>
<ci> KdADP </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850573" value="10000000" units="hour_inverse"/>
<parameter id="KdADP" metaid="_850585" value="0.76" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vMgAMP" name="MgAMP dissociation" metaid="metaid_0000081">
<listOfReactants>
<speciesReference species="MgAMP" metaid="_850597"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Mgf" metaid="_850609"/>
<speciesReference species="AMPf" metaid="_850621"/>
</listOfProducts>
<kineticLaw metaid="_850633">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> MgAMP </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Mgf </ci>
<ci> AMPf </ci>
</apply>
<ci> KdAMP </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850645" value="10000000" units="hour_inverse"/>
<parameter id="KdAMP" metaid="_850657" value="16.64" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vMgGri23P2" name="MgGri23P2 dissociation" metaid="metaid_0000082">
<listOfReactants>
<speciesReference species="MgGri23P2" metaid="_850669"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="Mgf" metaid="_850681"/>
<speciesReference species="Gri23P2f" metaid="_850693"/>
</listOfProducts>
<kineticLaw metaid="_850705">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> MgGri23P2 </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> Mgf </ci>
<ci> Gri23P2f </ci>
</apply>
<ci> Kd23P2G </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850717" value="10000000" units="hour_inverse"/>
<parameter id="Kd23P2G" metaid="_850729" value="1.667" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vP1NADP" name="P1NADP dissociation" metaid="metaid_0000083">
<listOfReactants>
<speciesReference species="P1NADP" metaid="_850741"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="P1f" metaid="_850753"/>
<speciesReference species="NADPf" metaid="_850765"/>
</listOfProducts>
<kineticLaw metaid="_850777">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> P1NADP </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> P1f </ci>
<ci> NADPf </ci>
</apply>
<ci> Kd1 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850789" value="10000000" units="hour_inverse"/>
<parameter id="Kd1" metaid="_850801" value="0.0002" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vP1NADPH" name="P1NADPH dissociation" metaid="metaid_0000084">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000084">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0006740"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="P1NADPH" metaid="_850813"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="P1f" metaid="_850825"/>
<speciesReference species="NADPHf" metaid="_850837"/>
</listOfProducts>
<kineticLaw metaid="_850849">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> P1NADPH </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> P1f </ci>
<ci> NADPHf </ci>
</apply>
<ci> Kd3 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850861" value="10000000" units="hour_inverse"/>
<parameter id="Kd3" metaid="_850873" value="1E-5" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vP2NADP" name="P2NADP dissociation" metaid="metaid_0000085">
<listOfReactants>
<speciesReference species="P2NADP" metaid="_850885"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="P2f" metaid="_850897"/>
<speciesReference species="NADPf" metaid="_850909"/>
</listOfProducts>
<kineticLaw metaid="_850921">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> P2NADP </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> P2f </ci>
<ci> NADPf </ci>
</apply>
<ci> Kd2 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_850933" value="10000000" units="hour_inverse"/>
<parameter id="Kd2" metaid="_850945" value="1E-5" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id="vP2NADPH" name="P2NADPH dissociation" metaid="metaid_0000086">
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqmodel="http://biomodels.net/model-qualifiers/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="#metaid_0000086">
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource="http://identifiers.org/obo.go/GO:0006735"/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference species="P2NADPH" metaid="_850957"/>
</listOfReactants>
<listOfProducts>
<speciesReference species="P2f" metaid="_850969"/>
<speciesReference species="NADPHf" metaid="_850981"/>
</listOfProducts>
<kineticLaw metaid="_850993">
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<times/>
<ci> compartment </ci>
<ci> EqMult </ci>
<apply>
<minus/>
<ci> P2NADPH </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> P2f </ci>
<ci> NADPHf </ci>
</apply>
<ci> Kd4 </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id="EqMult" metaid="_851005" value="10000000" units="hour_inverse"/>
<parameter id="Kd4" metaid="_851017" value="0.0002" units="mM"/>
</listOfParameters>
</kineticLaw>
</reaction>
</listOfReactions>
</model>
</sbml>
