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A single compartment model of pacemaking in dissasociated Substantia nigra neurons with hyperbolic tetrahedral geometry

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Description
A model is developed to study the membrane oscillations of a dissociated substantia nigra neuron, by describing its geometry based on a hyperbolic tetrahedron. The model demonstrates the dependance of these neurons on the L-type calcium channel for its autonomous pacemaking activity. Existence of stable limit cycles for important state variables establishes the robustness of the system.
Owner
Mathieu Deneux <mathieu.deneux@gmail.com>
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https://models.cellml.org/workspace/35c
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