Feedback control of T-cell receptor activation

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Description

Ligand engagement with the T-cell receptor (TCR) results in activation of a complex sequence of signalling events. Using a mathematical model, feedback loops of T-cell signalling explains the ability of the TCR to discriminate between ligands and provide a mechanism for sustained signalling.

Owner

Nurul Izza Ismail <nism576@aucklanduni.ac.nz>

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https://models.cellml.org/workspace/4fb

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