- Author:
- Nima <nafs080@aucklanduni.ac.nz>
- Date:
- 2019-07-21 09:46:02+12:00
- Desc:
- Modular version of glucose uptake model (contains water transporters and cell volume changes)
- Permanent Source URI:
- https://models.cellml.org/workspace/58c/rawfile/2ad89252015aa87ebc327c2d547bd99bc7629853/CFTR_flux.cellml
<?xml version='1.0'?>
<model name="CFTR_flux" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#">
<component name="CFTR">
<variable name="z_Cl" public_interface="in" units="dimensionless"/>
<variable name="R" public_interface="in" units="J_per_K_per_mol"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="Cl_i" public_interface="in" units="M"/>
<variable name="Cl_m" public_interface="in" units="M"/>
<variable name="V_A_Cl" public_interface="out" units="volt"/>
<variable name="v_mc" public_interface="in" units="volt"/>
<variable name="J_CFTR" public_interface="out" units="umol_per_s"/>
<variable name="J_CFTR1" public_interface="out" units="umol_per_s"/>
<variable name="I_CFTR" public_interface="out" units="uA"/>
<variable name="A_Apical" public_interface="in" units="m2"/>
<variable name="F" public_interface="in" units="C_per_mol"/>
<variable initial_value="1.4" name="G_CFTR" public_interface="out" units="S_per_m2"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J_CFTR</ci>
<apply>
<divide/>
<ci>I_CFTR</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>J_CFTR1</ci>
<apply>
<times/>
<ci>J_CFTR</ci>
<cn cellml:units="dimensionless" type="e-notation">36<sep/>8</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>V_A_Cl</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<ci>z_Cl</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Cl_m</ci>
<ci>Cl_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>I_CFTR</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless" type="e-notation">1<sep/>6</cn>
</apply>
<ci>G_CFTR</ci>
<ci>A_Apical</ci>
<apply>
<minus/>
<ci>v_mc</ci>
<ci>V_A_Cl</ci>
</apply>
</apply>
</apply>
</math>
</component>
</model>
