Location: Modular version of Glucose uptake (including water transport) @ e82595139c2e / SGLT1_flux.cellml
- Author:
- Nima <nafs080@aucklanduni.ac.nz>
- Date:
- 2019-07-31 13:22:01+12:00
- Desc:
- Updated values
- Permanent Source URI:
- https://models.cellml.org/workspace/58c/rawfile/e82595139c2e39aec218cbbf56fc10782a4ced52/SGLT1_flux.cellml
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<!--Link in Exposure : https://models.physiomeproject.org/exposure/4f0e5558031705df771326fb9bd90c28
Original Paper: Xing-Zhen Chen, Michael J Coady, Francis Jackson, Alfred Berteloot, and Jean-Yves Lapointe. Thermodynamic determination of the Na+: glucose coupling ratio for the human sglt1 cotransporter. -->
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<ci>k_45</ci>
</apply>
<apply>
<times/>
<ci>k_25</ci>
<ci>k_32</ci>
<ci>k_45</ci>
</apply>
<apply>
<times/>
<ci>k_25</ci>
<ci>k_32</ci>
<ci>k_43</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>epsilon</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
<ci>lambda</ci>
</apply>
<ci>ks_12</ci>
<ci>k0_23</ci>
<ci>k_34</ci>
<ci>k_45</ci>
<ci>k_56</ci>
<ci>k_61</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>J_Na_SGLT</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>n_SGLT</ci>
</apply>
<cn cellml:units="per_umol" type="e-notation">6.023<sep/>17</cn>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>epsilon</ci>
<apply>
<power/>
<ci>Na_m</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>glucose_m</ci>
</apply>
<apply>
<times/>
<ci>phi</ci>
<apply>
<power/>
<ci>Na_m</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<ci>gamma</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>alpha</ci>
<apply>
<times/>
<ci>beta</ci>
<ci>glucose_m</ci>
</apply>
<apply>
<times/>
<ci>chi</ci>
<apply>
<power/>
<ci>Na_m</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_m</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>glucose_m</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>I_Na_SGLT</ci>
<apply>
<times/>
<ci>J_Na_SGLT</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>J_Gl_SGLT</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>J_Na_SGLT</ci>
</apply>
</apply>
</math>
</component>
</model>