PKPD

Acikgoz, 2009
acikgoz_2009a.cellml
Acikgoz, 2009
acikgoz_2009b.cellml
Acikgoz, Karim, Giri, Schmidt-Heck, Bader, 2009
Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes
Acikgoz, Karim, Giri, Schmidt-Heck, Bader, 2009
Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes
Grange, Holford, Guentert, 2001
A pharmacokinetic model to predict the PK interaction of L-dopa and benserazide in rats (L-dopa)
Grange, Holford, Guentert, 2001
A pharmacokinetic model to predict the PK interaction of L-dopa and benserazide in rats (L-dopa + Benserazide)
Lockwood, Ewy, Hermann, Holford, 2006
Application of clinical trial simulation to compare proof-of-concept study designs for drugs with a slow onset of effect; an example in Alzheimer's disease
Overgaard, Holford, Rytved, Madsen, 2007
PKPD model of interleukin-21 effects on thermoregulation in monkeys (Baseline)
Overgaard, Holford, Rytved, Madsen, 2007
PKPD model of interleukin-21 effects on thermoregulation in monkeys (Pharmacodynamic)
Tham, Wang, Soo, Lee, Lee, Yong, Goh, Holford, 2008
A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients
Yang, Tong, McCarver, Hines, Beard, 2006
Population-Based Analysis of Methadone Distribution and Metabolism Using an Age-Dependent Physiologically Based Pharmacokinetic Model