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C C There are a total of 18 entries in the algebraic variable array. C There are a total of 9 entries in each of the rate and state variable arrays. C There are a total of 49 entries in the constant variable array. C C C VOI is time in component Environment (second). C CONSTS(1) is Eta_b in component Parameters (mmHg_sec). C CONSTS(2) is Rho_b in component Parameters (gram_per_cubic_meter). C CONSTS(3) is E_p in component Parameters (mmHg). C CONSTS(4) is r_p in component Parameters (meter). C CONSTS(5) is l_p in component Parameters (meter). C CONSTS(6) is h_p in component Parameters (meter). C CONSTS(7) is r_a0 in component Parameters (meter). C CONSTS(8) is h_a0 in component Parameters (meter). C CONSTS(9) is sigma_ae0 in component Parameters (mmHg). C CONSTS(10) is K_a_sigma in component Parameters (dimensionless). C CONSTS(11) is sigma_ac in component Parameters (mmHg). C CONSTS(12) is T_a_max0 in component Parameters (mmHg_m). C CONSTS(13) is r_am in component Parameters (meter). C CONSTS(14) is r_at in component Parameters (meter). C CONSTS(15) is n_am in component Parameters (dimensionless). C CONSTS(16) is Eta_a in component Parameters (mmHg_sec). C CONSTS(17) is Q_bl in component Parameters (cubic_m_per_sec). C CONSTS(18) is P_ic in component Parameters (mmHg). C CONSTS(19) is R_v in component Parameters (mmHg_sec_per_cubic_m). C CONSTS(20) is C_v in component Parameters (cubic_m_per_mmHg). C CONSTS(21) is P_ai in component Parameters (mmHg). C CONSTS(22) is T_myo0 in component Parameters (mmHg_m). C CONSTS(23) is T_myo_s in component Parameters (mmHg_m). C CONSTS(24) is Tau_myo in component Parameters (second). C CONSTS(25) is Tau_shear in component Parameters (second). C CONSTS(26) is G_myo in component Parameters (dimensionless). C CONSTS(27) is G_shear in component Parameters (dimensionless). C CONSTS(28) is G_neuro in component Parameters (dimensionless). C CONSTS(29) is G_meta in component Parameters (dimensionless). C CONSTS(30) is x_ini in component Parameters (dimensionless). C CONSTS(31) is Tau_neuro in component Parameters (second). C CONSTS(32) is Tau_meta in component Parameters (second). C CONSTS(33) is conc_CO2_a in component Parameters (mol_per_m3). C CONSTS(34) is M_CO2_0 in component Parameters (mol_per_sec). C CONSTS(35) is alpha_tv in component Parameters (dimensionless). C CONSTS(36) is beta_tv in component Parameters (mol_per_m3). C CONSTS(37) is vol_PVC in component Parameters (cubic_m). C CONSTS(38) is K_shear in component Parameters (second). C CONSTS(39) is K_Ra in component Parameters (mmHg_sec_m). C CONSTS(40) is conc_CO2_t_sp in component Parameters (mol_per_m3). C CONSTS(41) is f_Q in component Parameters (dimensionless). C CONSTS(42) is n_QM in component Parameters (dimensionless). C CONSTS(43) is K_Va in component Parameters (meter). C CONSTS(44) is P_vo in component Parameters (mmHg). C STATES(1) is Q_Lp in component PCA (cubic_m_per_sec). C STATES(2) is P_p in component PCA (mmHg). C CONSTS(47) is C_p in component PCA_Components (cubic_m_per_mmHg). C CONSTS(48) is L_p in component PCA_Components (mmHg_sec2_per_m3). C CONSTS(49) is R_p in component PCA_Components (mmHg_sec_per_cubic_m). C ALGBRC(1) is R_a in component AC_Components (mmHg_sec_per_cubic_m). C ALGBRC(12) is P_a in component Arteriolar_Circulation (mmHg). C ALGBRC(3) is C_a in component AC_Components (cubic_m_per_mmHg). C ALGBRC(14) is Q_a in component AC_Flow (cubic_m_per_sec). C STATES(3) is P_v in component Venous_Circulation (mmHg). C STATES(4) is r_a in component Arteriolar_Circulation (meter). C ALGBRC(5) is T_ae in component AC_Tension (mmHg_m). C ALGBRC(9) is T_am in component AC_Tension (mmHg_m). C ALGBRC(10) is T_av in component AC_Tension (mmHg_m). C ALGBRC(11) is T_a in component AC_Tension (mmHg_m). C ALGBRC(4) is h_a in component AC_Tension_Variables (meter). C ALGBRC(8) is T_a_max in component AC_Tension_Variables (mmHg_m). C ALGBRC(7) is M_s in component CBF_Regulation (dimensionless). C ALGBRC(6) is M_s1 in component CBF_Regulation (dimensionless). C STATES(5) is x_myo in component Myo_Regulation (dimensionless). C STATES(6) is x_shear in component Shear_Regulation (dimensionless). C STATES(7) is x_neuro in component Neuro_Regulation (dimensionless). C STATES(8) is x_meta in component Meta_Regulation (dimensionless). C ALGBRC(13) is A_myo in component Myo_Regulation (dimensionless). C ALGBRC(15) is A_shear in component Shear_Regulation (dimensionless). C ALGBRC(16) is A_neuro in component Neuro_Regulation (dimensionless). C ALGBRC(2) is A_Meta in component Meta_Regulation (dimensionless). C CONSTS(45) is G_a_Meta in component Meta_Regulation (m3_per_mol). C STATES(9) is conc_CO2_t in component Meta_CO2_Kinetics (mol_per_m3). C ALGBRC(17) is conc_CO2_v in component Meta_CO2_Kinetics (mol_per_m3). C ALGBRC(18) is M_CO2 in component VC_Meta_Stim (mol_per_sec). C CONSTS(46) is unity in component VC_Meta_Stim (dimensionless). C RATES(2) is d/dt P_p in component PCA (mmHg). C RATES(1) is d/dt Q_Lp in component PCA (cubic_m_per_sec). C RATES(4) is d/dt r_a in component Arteriolar_Circulation (meter). C RATES(3) is d/dt P_v in component Venous_Circulation (mmHg). C RATES(5) is d/dt x_myo in component Myo_Regulation (dimensionless). C RATES(6) is d/dt x_shear in component Shear_Regulation (dimensionless). C RATES(7) is d/dt x_neuro in component Neuro_Regulation (dimensionless). C RATES(8) is d/dt x_meta in component Meta_Regulation (dimensionless). C RATES(9) is d/dt conc_CO2_t in component Meta_CO2_Kinetics (mol_per_m3). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 3E-5 CONSTS(2) = 1.05E6 CONSTS(3) = 12E3 CONSTS(4) = 1.05E-3 CONSTS(5) = 8.6E-2 CONSTS(6) = 2.6E-4 CONSTS(7) = 7.5E-5 CONSTS(8) = 2.5E-5 CONSTS(9) = 11.19 CONSTS(10) = 4.5 CONSTS(11) = 41.32 CONSTS(12) = 1.50E-2 CONSTS(13) = 1.28E-4 CONSTS(14) = 1.74E-4 CONSTS(15) = 1.75 CONSTS(16) = 47.8 CONSTS(17) = 8.8E-7 CONSTS(18) = 10 CONSTS(19) = 1.6E7 CONSTS(20) = 2.5E-8 CONSTS(21) = 96.0 CONSTS(22) = 3.6E-3 CONSTS(23) = 3E-3 CONSTS(24) = 7 CONSTS(25) = 60 CONSTS(26) = 4 CONSTS(27) = 0 CONSTS(28) = -0.7 CONSTS(29) = 0 CONSTS(30) = 0 CONSTS(31) = 5 CONSTS(32) = 15 CONSTS(33) = 20.65 CONSTS(34) = 1.35E-7 CONSTS(35) = 0.96 CONSTS(36) = 8.9 CONSTS(37) = 5.99E-6 CONSTS(38) = 5.2E-7 CONSTS(39) = 2.5E-9 CONSTS(40) = 12.41 CONSTS(41) = 1.25 CONSTS(42) = 2.2 CONSTS(43) = 120 CONSTS(44) = 14 STATES(1) = 8.8E-7 STATES(2) = 91 STATES(3) = 21 STATES(4) = 7.7E-5 STATES(5) = 0 STATES(6) = 0 STATES(7) = 0 STATES(8) = 0 CONSTS(45) = 0.59 STATES(9) = 12.41 CONSTS(46) = 1 CONSTS(47) = (( 3.00000* 3.14159265358979*CONSTS(4) ** 2.00000*CONSTS(4)/CONSTS(6)+1.00000 ** 2.00000)/( CONSTS(3)*(( 2.00000*CONSTS(4))/CONSTS(6)+1.00000)))*CONSTS(5) CONSTS(48) = (CONSTS(2)/( 3.14159265358979*CONSTS(4) ** 2.00000))*CONSTS(5)*7.50000e-06 CONSTS(49) = (( 8.00000*CONSTS(1))/( 3.14159265358979*CONSTS(4) ** 4.00000))*CONSTS(5) RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) RATES(1) = ((CONSTS(21) - STATES(2)) - STATES(1)*CONSTS(49))/CONSTS(48) ALGBRC(2) = CONSTS(45)*(STATES(9) - CONSTS(40)) RATES(8) = (ALGBRC(2) - STATES(8))/CONSTS(32) ALGBRC(1) = CONSTS(39)/STATES(4) ** 4.00000 ALGBRC(4) = (STATES(4) ** 2.00000+ 2.00000*CONSTS(7)*CONSTS(8)+CONSTS(8) ** 2.00000) ** (1.0 / 2) - STATES(4) ALGBRC(5) = ALGBRC(4)*( CONSTS(9)*(EXP(( CONSTS(10)*(STATES(4) - CONSTS(7)))/CONSTS(7)) - 1.00000) - CONSTS(11)) ALGBRC(6) = CONSTS(26)*STATES(5)+ CONSTS(27)*STATES(6)+ CONSTS(28)*STATES(7)+ CONSTS(29)*STATES(8)+CONSTS(30) ALGBRC(7) = (EXP( 2.00000*ALGBRC(6)) - 1.00000)/(EXP( 2.00000*ALGBRC(6))+1.00000) ALGBRC(8) = CONSTS(12)*(1.00000+ALGBRC(7)) ALGBRC(9) = ALGBRC(8)*EXP(- ABS((STATES(4) - CONSTS(13))/(CONSTS(14) - CONSTS(13))) ** CONSTS(15)) RATES(4) = ( CONSTS(7)*(( STATES(2)*(ALGBRC(1)+CONSTS(19))*STATES(4)+ STATES(3)*ALGBRC(1)*STATES(4)) - (ALGBRC(5)+ALGBRC(9)+ CONSTS(18)*(STATES(4)+ALGBRC(4)))*( 2.00000*ALGBRC(1)+CONSTS(19))))/( CONSTS(7)*STATES(4) ** 2.00000*CONSTS(43)*ALGBRC(1)*(ALGBRC(1)+CONSTS(19))+ CONSTS(16)*ALGBRC(4)*( 2.00000*ALGBRC(1)+CONSTS(19))) ALGBRC(10) = (CONSTS(16)/CONSTS(7))*RATES(4)*ALGBRC(4) ALGBRC(11) = ALGBRC(5)+ALGBRC(9)+ALGBRC(10) ALGBRC(12) = (ALGBRC(11)+ CONSTS(18)*(STATES(4)+ALGBRC(4)))/STATES(4) RATES(2) = ( 2.00000*(( STATES(1)*ALGBRC(1) - 2.00000*STATES(2))+ 2.00000*ALGBRC(12)))/( ALGBRC(1)*CONSTS(47)) RATES(3) = (2.00000/CONSTS(20))*((ALGBRC(12) - STATES(3))/(ALGBRC(1)+CONSTS(19)) - (STATES(3) - CONSTS(44))/CONSTS(19)) ALGBRC(13) = (ALGBRC(11) - CONSTS(22))/CONSTS(23) RATES(5) = (ALGBRC(13) - STATES(5))/CONSTS(24) ALGBRC(14) = ( 2.00000*(ALGBRC(12) - STATES(3)))/(ALGBRC(1)+CONSTS(19)) ALGBRC(15) = ( CONSTS(38)*ALGBRC(14))/STATES(4) ** 3.00000 - 1.00000 RATES(6) = (ALGBRC(15) - STATES(6))/CONSTS(25) ALGBRC(16) = TERNRY(VOI.GE.1.00000, 1.00000, 0.00000) RATES(7) = (ALGBRC(16) - STATES(7))/CONSTS(31) ALGBRC(17) = CONSTS(35)*STATES(9)+CONSTS(36) ALGBRC(18) = CONSTS(34)*(CONSTS(46)+ ALGBRC(16)*((CONSTS(41) - CONSTS(46))/CONSTS(42))) RATES(9) = (1.00000/CONSTS(37))*(ALGBRC(18) - ALGBRC(14)*(ALGBRC(17) - CONSTS(33))) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = CONSTS(45)*(STATES(9) - CONSTS(40)) ALGBRC(1) = CONSTS(39)/STATES(4) ** 4.00000 ALGBRC(4) = (STATES(4) ** 2.00000+ 2.00000*CONSTS(7)*CONSTS(8)+CONSTS(8) ** 2.00000) ** (1.0 / 2) - STATES(4) ALGBRC(5) = ALGBRC(4)*( CONSTS(9)*(EXP(( CONSTS(10)*(STATES(4) - CONSTS(7)))/CONSTS(7)) - 1.00000) - CONSTS(11)) ALGBRC(6) = CONSTS(26)*STATES(5)+ CONSTS(27)*STATES(6)+ CONSTS(28)*STATES(7)+ CONSTS(29)*STATES(8)+CONSTS(30) ALGBRC(7) = (EXP( 2.00000*ALGBRC(6)) - 1.00000)/(EXP( 2.00000*ALGBRC(6))+1.00000) ALGBRC(8) = CONSTS(12)*(1.00000+ALGBRC(7)) ALGBRC(9) = ALGBRC(8)*EXP(- ABS((STATES(4) - CONSTS(13))/(CONSTS(14) - CONSTS(13))) ** CONSTS(15)) ALGBRC(10) = (CONSTS(16)/CONSTS(7))*RATES(4)*ALGBRC(4) ALGBRC(11) = ALGBRC(5)+ALGBRC(9)+ALGBRC(10) ALGBRC(12) = (ALGBRC(11)+ CONSTS(18)*(STATES(4)+ALGBRC(4)))/STATES(4) ALGBRC(13) = (ALGBRC(11) - CONSTS(22))/CONSTS(23) ALGBRC(14) = ( 2.00000*(ALGBRC(12) - STATES(3)))/(ALGBRC(1)+CONSTS(19)) ALGBRC(15) = ( CONSTS(38)*ALGBRC(14))/STATES(4) ** 3.00000 - 1.00000 ALGBRC(16) = TERNRY(VOI.GE.1.00000, 1.00000, 0.00000) ALGBRC(17) = CONSTS(35)*STATES(9)+CONSTS(36) ALGBRC(18) = CONSTS(34)*(CONSTS(46)+ ALGBRC(16)*((CONSTS(41) - CONSTS(46))/CONSTS(42))) ALGBRC(3) = 1.03120/ALGBRC(1) RETURN END REAL FUNCTION TERNRY(TEST, VALA, VALB) LOGICAL TEST REAL VALA, VALB IF (TEST) THEN TERNRY = VALA ELSE TERNRY = VALB ENDIF RETURN END