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C C There are a total of 17 entries in the algebraic variable array. C There are a total of 7 entries in each of the rate and state variable arrays. C There are a total of 1 entries in the constant variable array. C C C VOI is time in component environment (millisecond). C STATES(1) is V in component membrane (millivolt). C CONSTS(1) is Cm in component membrane (microF_per_cm2). C ALGBRC(1) is i_Na in component sodium_channel (microA_per_cm2). C ALGBRC(8) is i_K in component potassium_channel (microA_per_cm2). C ALGBRC(15) is i_Leak in component leakage_current (microA_per_cm2). C ALGBRC(16) is i_s in component calcium_channel (microA_per_cm2). C ALGBRC(17) is i_h in component hyperpolarization_activated_channel (microA_per_cm2). C STATES(2) is m in component sodium_channel_m_gate (dimensionless). C STATES(3) is h in component sodium_channel_h_gate (dimensionless). C ALGBRC(2) is alpha_m in component sodium_channel_m_gate (per_millisecond). C ALGBRC(9) is beta_m in component sodium_channel_m_gate (per_millisecond). C ALGBRC(3) is alpha_h in component sodium_channel_h_gate (per_millisecond). C ALGBRC(10) is beta_h in component sodium_channel_h_gate (per_millisecond). C STATES(4) is n in component potassium_channel_n_gate (dimensionless). C ALGBRC(4) is alpha_n in component potassium_channel_n_gate (per_millisecond). C ALGBRC(11) is beta_n in component potassium_channel_n_gate (per_millisecond). C STATES(5) is d in component calcium_channel_d_gate (dimensionless). C STATES(6) is f in component calcium_channel_f_gate (dimensionless). C ALGBRC(5) is alpha_d in component calcium_channel_d_gate (per_millisecond). C ALGBRC(12) is beta_d in component calcium_channel_d_gate (per_millisecond). C ALGBRC(6) is alpha_f in component calcium_channel_f_gate (per_millisecond). C ALGBRC(13) is beta_f in component calcium_channel_f_gate (per_millisecond). C STATES(7) is q in component hyperpolarization_activated_channel_q_gate (dimensionless). C ALGBRC(7) is alpha_q in component hyperpolarization_activated_channel_q_gate (per_millisecond). C ALGBRC(14) is beta_q in component hyperpolarization_activated_channel_q_gate (per_millisecond). C RATES(1) is d/dt V in component membrane (millivolt). C RATES(2) is d/dt m in component sodium_channel_m_gate (dimensionless). C RATES(3) is d/dt h in component sodium_channel_h_gate (dimensionless). C RATES(4) is d/dt n in component potassium_channel_n_gate (dimensionless). C RATES(5) is d/dt d in component calcium_channel_d_gate (dimensionless). C RATES(6) is d/dt f in component calcium_channel_f_gate (dimensionless). C RATES(7) is d/dt q in component hyperpolarization_activated_channel_q_gate (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) STATES(1) = -62.83 CONSTS(1) = 1 STATES(2) = 0.047938 STATES(3) = 0.95994 STATES(4) = 0.509494 STATES(5) = 0.000032 STATES(6) = 1 STATES(7) = 0.010759 RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = ( 1.00000*(STATES(1)+37.0000))/(- EXP((STATES(1)+37.0000)/- 10.0000)+1.00000) ALGBRC(9) = 40.0000*EXP((STATES(1)+62.0000)/- 17.8000) RATES(2) = ALGBRC(2)*(1.00000 - STATES(2)) - ALGBRC(9)*STATES(2) ALGBRC(3) = 0.00120900*EXP((STATES(1)+20.0000)/- 6.53400) ALGBRC(10) = 1.00000/(1.00000+EXP((STATES(1)+30.0000)/- 10.0000)) RATES(3) = ALGBRC(3)*(1.00000 - STATES(3)) - ALGBRC(10)*STATES(3) ALGBRC(4) = ( 0.00900000*1.00000)/(1.00000+EXP(- (STATES(1)+3.80000)/9.71000))+0.000600000 ALGBRC(11) = ( - 0.000225000*(STATES(1)+40.0000))/(1.00000 - EXP((STATES(1)+40.0000)/13.3000)) RATES(4) = ALGBRC(4)*(1.00000 - STATES(4)) - ALGBRC(11)*STATES(4) ALGBRC(5) = ( 0.0145000*(STATES(1)+35.0000))/(1.00000 - EXP(- (STATES(1)+35.0000)/2.50000))+( 0.0312500*STATES(1))/(1.00000 - EXP(- STATES(1)/4.80000)) ALGBRC(12) = ( - 0.00421000*(STATES(1) - 5.00000))/(- EXP((STATES(1) - 5.00000)/2.50000)+1.00000) RATES(5) = ALGBRC(5)*(1.00000 - STATES(5)) - ALGBRC(12)*STATES(5) ALGBRC(6) = ( - 0.000355000*(STATES(1)+20.0000))/(- EXP((STATES(1)+20.0000)/5.63300)+1.00000) ALGBRC(13) = ( 0.000944000*(STATES(1)+60.0000))/(1.00000+EXP(- (STATES(1)+29.5000)/4.16000)) RATES(6) = ALGBRC(6)*(1.00000 - STATES(6)) - ALGBRC(13)*STATES(6) ALGBRC(7) = ( 0.000340000*(STATES(1)+100.000))/(EXP((STATES(1)+100.000)/4.40000) - 1.00000)+4.95000e-05 ALGBRC(14) = ( 0.000500000*(STATES(1)+40.0000))/(1.00000 - EXP(- (STATES(1)+40.0000)/6.00000))+8.45000e-05 RATES(7) = ALGBRC(7)*(1.00000 - STATES(7)) - ALGBRC(14)*STATES(7) ALGBRC(1) = 0.500000*STATES(2) ** 3.00000*STATES(3)*(STATES(1) - 30.0000) ALGBRC(8) = ( 0.700000*STATES(4)*(EXP( 0.0277000*(STATES(1)+90.0000)) - 1.00000))/EXP( 0.0277000*(STATES(1)+40.0000)) ALGBRC(15) = 0.800000*(1.00000 - EXP(- (STATES(1)+60.0000)/20.0000)) ALGBRC(16) = 12.5000*( 0.950000*STATES(5)+0.0500000)*( 0.950000*STATES(6)+0.0500000)*(EXP((STATES(1) - 10.0000)/15.0000) - 1.00000) ALGBRC(17) = 0.400000*STATES(7)*(STATES(1)+45.0000) RATES(1) = - (ALGBRC(1)+ALGBRC(8)+ALGBRC(15)+ALGBRC(16)+ALGBRC(17))/CONSTS(1) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(2) = ( 1.00000*(STATES(1)+37.0000))/(- EXP((STATES(1)+37.0000)/- 10.0000)+1.00000) ALGBRC(9) = 40.0000*EXP((STATES(1)+62.0000)/- 17.8000) ALGBRC(3) = 0.00120900*EXP((STATES(1)+20.0000)/- 6.53400) ALGBRC(10) = 1.00000/(1.00000+EXP((STATES(1)+30.0000)/- 10.0000)) ALGBRC(4) = ( 0.00900000*1.00000)/(1.00000+EXP(- (STATES(1)+3.80000)/9.71000))+0.000600000 ALGBRC(11) = ( - 0.000225000*(STATES(1)+40.0000))/(1.00000 - EXP((STATES(1)+40.0000)/13.3000)) ALGBRC(5) = ( 0.0145000*(STATES(1)+35.0000))/(1.00000 - EXP(- (STATES(1)+35.0000)/2.50000))+( 0.0312500*STATES(1))/(1.00000 - EXP(- STATES(1)/4.80000)) ALGBRC(12) = ( - 0.00421000*(STATES(1) - 5.00000))/(- EXP((STATES(1) - 5.00000)/2.50000)+1.00000) ALGBRC(6) = ( - 0.000355000*(STATES(1)+20.0000))/(- EXP((STATES(1)+20.0000)/5.63300)+1.00000) ALGBRC(13) = ( 0.000944000*(STATES(1)+60.0000))/(1.00000+EXP(- (STATES(1)+29.5000)/4.16000)) ALGBRC(7) = ( 0.000340000*(STATES(1)+100.000))/(EXP((STATES(1)+100.000)/4.40000) - 1.00000)+4.95000e-05 ALGBRC(14) = ( 0.000500000*(STATES(1)+40.0000))/(1.00000 - EXP(- (STATES(1)+40.0000)/6.00000))+8.45000e-05 ALGBRC(1) = 0.500000*STATES(2) ** 3.00000*STATES(3)*(STATES(1) - 30.0000) ALGBRC(8) = ( 0.700000*STATES(4)*(EXP( 0.0277000*(STATES(1)+90.0000)) - 1.00000))/EXP( 0.0277000*(STATES(1)+40.0000)) ALGBRC(15) = 0.800000*(1.00000 - EXP(- (STATES(1)+60.0000)/20.0000)) ALGBRC(16) = 12.5000*( 0.950000*STATES(5)+0.0500000)*( 0.950000*STATES(6)+0.0500000)*(EXP((STATES(1) - 10.0000)/15.0000) - 1.00000) ALGBRC(17) = 0.400000*STATES(7)*(STATES(1)+45.0000) RETURN END