Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 9 entries in the algebraic variable array.
There are a total of 22 entries in each of the rate and state variable arrays.
There are a total of 45 entries in the constant variable array.
*/
/*
* VOI is time in component environment (second).
* STATES[0] is T2 in component T2 (micromolar).
* ALGEBRAIC[0] is Vmax in component T2 (flux).
* CONSTANTS[37] is KR in component T2 (molar).
* STATES[1] is LT2 in component LT2 (micromolar).
* STATES[2] is T2R in component T2R (micromolar).
* CONSTANTS[0] is R in component R (micromolar).
* STATES[3] is T3 in component T3 (micromolar).
* CONSTANTS[1] is L in component L (micromolar).
* STATES[4] is Bp in component Bp (micromolar).
* STATES[5] is T2p in component T2p (micromolar).
* CONSTANTS[2] is Y0 in component Y0 (micromolar).
* STATES[6] is Yp in component Yp (micromolar).
* CONSTANTS[3] is B0 in component B0 (micromolar).
* CONSTANTS[4] is k5 in component model_parameters (second_order_rate_constant).
* CONSTANTS[5] is k_5 in component model_parameters (first_order_rate_constant).
* CONSTANTS[6] is k8 in component model_parameters (first_order_rate_constant).
* CONSTANTS[7] is k_1 in component model_parameters (second_order_rate_constant).
* CONSTANTS[8] is ky in component model_parameters (second_order_rate_constant).
* CONSTANTS[9] is kb in component model_parameters (second_order_rate_constant).
* CONSTANTS[10] is k1a in component model_parameters (first_order_rate_constant).
* CONSTANTS[11] is k1b in component model_parameters (second_order_rate_constant).
* CONSTANTS[12] is k1c in component model_parameters (first_order_rate_constant).
* ALGEBRAIC[1] is Vmax in component T3 (flux).
* CONSTANTS[38] is KR in component T3 (molar).
* STATES[7] is LT3 in component LT3 (micromolar).
* STATES[8] is T3R in component T3R (micromolar).
* STATES[9] is T4 in component T4 (micromolar).
* STATES[10] is T3p in component T3p (micromolar).
* CONSTANTS[13] is k6 in component model_parameters (second_order_rate_constant).
* CONSTANTS[14] is k_6 in component model_parameters (first_order_rate_constant).
* CONSTANTS[15] is k9 in component model_parameters (first_order_rate_constant).
* CONSTANTS[16] is k_2 in component model_parameters (second_order_rate_constant).
* CONSTANTS[17] is k2a in component model_parameters (first_order_rate_constant).
* CONSTANTS[18] is k2b in component model_parameters (second_order_rate_constant).
* CONSTANTS[19] is k2c in component model_parameters (first_order_rate_constant).
* STATES[11] is LT4 in component LT4 (micromolar).
* STATES[12] is T4p in component T4p (micromolar).
* CONSTANTS[20] is k7 in component model_parameters (second_order_rate_constant).
* CONSTANTS[21] is k_7 in component model_parameters (first_order_rate_constant).
* CONSTANTS[22] is k10 in component model_parameters (first_order_rate_constant).
* ALGEBRAIC[2] is Vmax in component T2p (flux).
* CONSTANTS[39] is KR in component T2p (molar).
* STATES[13] is LT2p in component LT2p (micromolar).
* STATES[14] is T2pR in component T2pR (micromolar).
* ALGEBRAIC[3] is Vmax in component T3p (flux).
* CONSTANTS[40] is KR in component T3p (molar).
* STATES[15] is LT3p in component LT3p (micromolar).
* STATES[16] is T3pR in component T3pR (micromolar).
* STATES[17] is LT4p in component LT4p (micromolar).
* ALGEBRAIC[4] is Vmax in component LT2 (flux).
* CONSTANTS[41] is KR in component LT2 (molar).
* STATES[18] is LT2R in component LT2R (micromolar).
* CONSTANTS[23] is k11 in component model_parameters (first_order_rate_constant).
* CONSTANTS[24] is k_3 in component model_parameters (second_order_rate_constant).
* CONSTANTS[25] is k3a in component model_parameters (first_order_rate_constant).
* CONSTANTS[26] is k3b in component model_parameters (second_order_rate_constant).
* CONSTANTS[27] is k3c in component model_parameters (first_order_rate_constant).
* ALGEBRAIC[5] is Vmax in component LT3 (flux).
* CONSTANTS[42] is KR in component LT3 (molar).
* STATES[19] is LT3R in component LT3R (micromolar).
* CONSTANTS[28] is k12 in component model_parameters (first_order_rate_constant).
* CONSTANTS[29] is k_4 in component model_parameters (second_order_rate_constant).
* CONSTANTS[30] is k4a in component model_parameters (first_order_rate_constant).
* CONSTANTS[31] is k4b in component model_parameters (second_order_rate_constant).
* CONSTANTS[32] is k4c in component model_parameters (first_order_rate_constant).
* CONSTANTS[33] is k13 in component model_parameters (first_order_rate_constant).
* ALGEBRAIC[6] is Vmax in component LT2p (flux).
* CONSTANTS[43] is KR in component LT2p (molar).
* STATES[20] is LT2pR in component LT2pR (micromolar).
* ALGEBRAIC[7] is Vmax in component LT3p (flux).
* CONSTANTS[44] is KR in component LT3p (molar).
* STATES[21] is LT3pR in component LT3pR (micromolar).
* ALGEBRAIC[8] is P in component P (micromolar).
* CONSTANTS[34] is Z in component Z (micromolar).
* CONSTANTS[35] is k_y in component model_parameters (second_order_rate_constant).
* CONSTANTS[36] is k_b in component model_parameters (first_order_rate_constant).
* RATES[0] is d/dt T2 in component T2 (micromolar).
* RATES[3] is d/dt T3 in component T3 (micromolar).
* RATES[9] is d/dt T4 in component T4 (micromolar).
* RATES[5] is d/dt T2p in component T2p (micromolar).
* RATES[10] is d/dt T3p in component T3p (micromolar).
* RATES[12] is d/dt T4p in component T4p (micromolar).
* RATES[1] is d/dt LT2 in component LT2 (micromolar).
* RATES[7] is d/dt LT3 in component LT3 (micromolar).
* RATES[11] is d/dt LT4 in component LT4 (micromolar).
* RATES[13] is d/dt LT2p in component LT2p (micromolar).
* RATES[15] is d/dt LT3p in component LT3p (micromolar).
* RATES[17] is d/dt LT4p in component LT4p (micromolar).
* RATES[6] is d/dt Yp in component Yp (micromolar).
* RATES[4] is d/dt Bp in component Bp (micromolar).
* RATES[2] is d/dt T2R in component T2R (micromolar).
* RATES[8] is d/dt T3R in component T3R (micromolar).
* RATES[14] is d/dt T2pR in component T2pR (micromolar).
* RATES[16] is d/dt T3pR in component T3pR (micromolar).
* RATES[18] is d/dt LT2R in component LT2R (micromolar).
* RATES[19] is d/dt LT3R in component LT3R (micromolar).
* RATES[20] is d/dt LT2pR in component LT2pR (micromolar).
* RATES[21] is d/dt LT3pR in component LT3pR (micromolar).
* There are a total of 0 condition variables.
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
STATES[0] = 0.01;
STATES[1] = 0.01;
STATES[2] = 0.01;
CONSTANTS[0] = 0.3;
STATES[3] = 0.01;
CONSTANTS[1] = 3.0;
STATES[4] = 0.01;
STATES[5] = 0.01;
CONSTANTS[2] = 20.0;
STATES[6] = 0.01;
CONSTANTS[3] = 1.7;
CONSTANTS[4] = 7E7;
CONSTANTS[5] = 70.0;
CONSTANTS[6] = 15.0;
CONSTANTS[7] = 4E5;
CONSTANTS[8] = 3E7;
CONSTANTS[9] = 8E5;
CONSTANTS[10] = 10;
CONSTANTS[11] = 17;
CONSTANTS[12] = 0.17;
STATES[7] = 0.01;
STATES[8] = 0.01;
STATES[9] = 0.01;
STATES[10] = 0.01;
CONSTANTS[13] = 7E7;
CONSTANTS[14] = 70.0;
CONSTANTS[15] = 45.0;
CONSTANTS[16] = 3E4;
CONSTANTS[17] = 10;
CONSTANTS[18] = 17;
CONSTANTS[19] = 0.017;
STATES[11] = 0.01;
STATES[12] = 0.01;
CONSTANTS[20] = 7E7;
CONSTANTS[21] = 70.0;
CONSTANTS[22] = 48.0;
STATES[13] = 0.01;
STATES[14] = 0.01;
STATES[15] = 0.01;
STATES[16] = 0.01;
STATES[17] = 0.01;
STATES[18] = 0.01;
CONSTANTS[23] = 0.0;
CONSTANTS[24] = 4E5;
CONSTANTS[25] = 10;
CONSTANTS[26] = 17;
CONSTANTS[27] = 5.1;
STATES[19] = 0.01;
CONSTANTS[28] = 16.5;
CONSTANTS[29] = 3E4;
CONSTANTS[30] = 10;
CONSTANTS[31] = 17;
CONSTANTS[32] = 0.51;
CONSTANTS[33] = 34.56;
STATES[20] = 0.01;
STATES[21] = 0.01;
CONSTANTS[34] = 40.0;
CONSTANTS[35] = 5E5;
CONSTANTS[36] = 0.35;
CONSTANTS[37] = (CONSTANTS[10]+CONSTANTS[12])/CONSTANTS[11];
CONSTANTS[38] = (CONSTANTS[17]+CONSTANTS[19])/CONSTANTS[18];
CONSTANTS[39] = (CONSTANTS[10]+CONSTANTS[12])/CONSTANTS[11];
CONSTANTS[40] = (CONSTANTS[17]+CONSTANTS[19])/CONSTANTS[18];
CONSTANTS[41] = (CONSTANTS[25]+CONSTANTS[27])/CONSTANTS[26];
CONSTANTS[42] = (CONSTANTS[30]+CONSTANTS[32])/CONSTANTS[31];
CONSTANTS[43] = (CONSTANTS[25]+CONSTANTS[27])/CONSTANTS[26];
CONSTANTS[44] = (CONSTANTS[30]+CONSTANTS[32])/CONSTANTS[31];
RATES[0] = 0.1001;
RATES[3] = 0.1001;
RATES[9] = 0.1001;
RATES[5] = 0.1001;
RATES[10] = 0.1001;
RATES[12] = 0.1001;
RATES[1] = 0.1001;
RATES[7] = 0.1001;
RATES[11] = 0.1001;
RATES[13] = 0.1001;
RATES[15] = 0.1001;
RATES[17] = 0.1001;
RATES[6] = 0.1001;
RATES[4] = 0.1001;
RATES[2] = 0.1001;
RATES[8] = 0.1001;
RATES[14] = 0.1001;
RATES[16] = 0.1001;
RATES[18] = 0.1001;
RATES[19] = 0.1001;
RATES[20] = 0.1001;
RATES[21] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[0] - ( CONSTANTS[5]*STATES[1]+ CONSTANTS[7]*STATES[4]*STATES[3]+ CONSTANTS[8]*STATES[5]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[5]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[4]*CONSTANTS[1]*STATES[0]+ CONSTANTS[6]*STATES[0]+ ALGEBRAIC[0]*(STATES[0]/(CONSTANTS[37]+STATES[0])));
resid[1] = RATES[3] - ( CONSTANTS[14]*STATES[7]+ CONSTANTS[16]*STATES[4]*STATES[9]+ CONSTANTS[8]*STATES[10]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[10]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[13]*CONSTANTS[1]*STATES[3]+ CONSTANTS[15]*STATES[3]+ ALGEBRAIC[1]*(STATES[3]/(CONSTANTS[38]+STATES[3])));
resid[2] = RATES[9] - ( CONSTANTS[21]*STATES[11]+ CONSTANTS[8]*STATES[12]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[12]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[20]*CONSTANTS[1]*STATES[9]+ CONSTANTS[22]*STATES[9]);
resid[3] = RATES[5] - ( CONSTANTS[5]*STATES[13]+ CONSTANTS[7]*STATES[4]*STATES[10]+ CONSTANTS[8]*STATES[0]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[0]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[4]*CONSTANTS[1]*STATES[5]+ CONSTANTS[6]*STATES[5]+ ALGEBRAIC[2]*(STATES[5]/(CONSTANTS[39]+STATES[5])));
resid[4] = RATES[10] - ( CONSTANTS[14]*STATES[15]+ CONSTANTS[16]*STATES[4]*STATES[12]+ CONSTANTS[8]*STATES[3]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[3]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[13]*CONSTANTS[1]*STATES[10]+ CONSTANTS[15]*STATES[10]+ ALGEBRAIC[3]*(STATES[10]/(CONSTANTS[40]+STATES[10])));
resid[5] = RATES[12] - ( CONSTANTS[21]*STATES[17]+ CONSTANTS[8]*STATES[9]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[9]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[20]*CONSTANTS[1]*STATES[12]+ CONSTANTS[22]*STATES[12]);
resid[6] = RATES[1] - ( CONSTANTS[5]*STATES[0]+ CONSTANTS[24]*STATES[4]*STATES[7]+ CONSTANTS[8]*STATES[13]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[13]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[4]*CONSTANTS[1]*STATES[1]+ CONSTANTS[23]*STATES[1]+ ALGEBRAIC[4]*(STATES[1]/(CONSTANTS[41]+STATES[1])));
resid[7] = RATES[7] - ( CONSTANTS[14]*STATES[3]+ CONSTANTS[29]*STATES[4]*STATES[11]+ CONSTANTS[8]*STATES[15]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[15]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[13]*CONSTANTS[1]*STATES[7]+ CONSTANTS[28]*STATES[7]+ ALGEBRAIC[5]*(STATES[7]/(CONSTANTS[42]+STATES[7])));
resid[8] = RATES[11] - ( CONSTANTS[21]*STATES[9]+ CONSTANTS[8]*STATES[17]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[17]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[20]*CONSTANTS[1]*STATES[11]+ CONSTANTS[33]*STATES[11]);
resid[9] = RATES[13] - ( CONSTANTS[5]*STATES[5]+ CONSTANTS[24]*STATES[4]*STATES[15]+ CONSTANTS[8]*STATES[1]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[1]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[4]*CONSTANTS[1]*STATES[13]+ CONSTANTS[23]*STATES[13]+ ALGEBRAIC[6]*(STATES[13]/(CONSTANTS[43]+STATES[13])));
resid[10] = RATES[15] - ( CONSTANTS[14]*STATES[10]+ CONSTANTS[29]*STATES[4]*STATES[17]+ CONSTANTS[8]*STATES[7]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[7]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[13]*CONSTANTS[1]*STATES[15]+ CONSTANTS[28]*STATES[15]+ ALGEBRAIC[7]*(STATES[15]/(CONSTANTS[44]+STATES[15])));
resid[11] = RATES[17] - ( CONSTANTS[21]*STATES[12]+ CONSTANTS[8]*STATES[17]*(CONSTANTS[2] - STATES[6])+ CONSTANTS[9]*STATES[17]*(CONSTANTS[3] - STATES[4])) - ( CONSTANTS[20]*CONSTANTS[1]*STATES[17]+ CONSTANTS[33]*STATES[17]);
resid[12] = RATES[6] - CONSTANTS[8]*ALGEBRAIC[8]*(CONSTANTS[2] - STATES[6]) - CONSTANTS[35]*CONSTANTS[34]*STATES[6];
resid[13] = RATES[4] - CONSTANTS[9]*ALGEBRAIC[8]*(CONSTANTS[3] - STATES[4]) - CONSTANTS[36]*STATES[4];
resid[14] = RATES[2] - CONSTANTS[11]*STATES[0]*CONSTANTS[0] - ( CONSTANTS[10]*STATES[2]+ CONSTANTS[12]*STATES[2]);
resid[15] = RATES[8] - CONSTANTS[18]*STATES[3]*CONSTANTS[0] - ( CONSTANTS[17]*STATES[8]+ CONSTANTS[19]*STATES[8]);
resid[16] = RATES[14] - CONSTANTS[11]*STATES[5]*CONSTANTS[0] - ( CONSTANTS[10]*STATES[14]+ CONSTANTS[12]*STATES[14]);
resid[17] = RATES[16] - CONSTANTS[18]*STATES[10]*CONSTANTS[0] - ( CONSTANTS[17]*STATES[16]+ CONSTANTS[19]*STATES[16]);
resid[18] = RATES[18] - CONSTANTS[26]*STATES[1]*CONSTANTS[0] - ( CONSTANTS[25]*STATES[18]+ CONSTANTS[27]*STATES[18]);
resid[19] = RATES[19] - CONSTANTS[31]*STATES[7]*CONSTANTS[0] - ( CONSTANTS[30]*STATES[19]+ CONSTANTS[32]*STATES[19]);
resid[20] = RATES[20] - CONSTANTS[26]*STATES[13]*CONSTANTS[0] - ( CONSTANTS[25]*STATES[20]+ CONSTANTS[27]*STATES[20]);
resid[21] = RATES[21] - CONSTANTS[31]*STATES[15]*CONSTANTS[0] - ( CONSTANTS[30]*STATES[21]+ CONSTANTS[32]*STATES[21]);
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = CONSTANTS[12]*(CONSTANTS[0]+STATES[2]);
ALGEBRAIC[1] = CONSTANTS[19]*(CONSTANTS[0]+STATES[8]);
ALGEBRAIC[2] = CONSTANTS[12]*(CONSTANTS[0]+STATES[14]);
ALGEBRAIC[3] = CONSTANTS[19]*(CONSTANTS[0]+STATES[16]);
ALGEBRAIC[4] = CONSTANTS[27]*(CONSTANTS[0]+STATES[18]);
ALGEBRAIC[5] = CONSTANTS[32]*(CONSTANTS[0]+STATES[19]);
ALGEBRAIC[6] = CONSTANTS[27]*(CONSTANTS[0]+STATES[20]);
ALGEBRAIC[7] = CONSTANTS[32]*(CONSTANTS[0]+STATES[21]);
ALGEBRAIC[8] = STATES[5]+STATES[13]+STATES[10]+STATES[15]+STATES[12]+STATES[17];
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
SI[8] = 1.0;
SI[9] = 1.0;
SI[10] = 1.0;
SI[11] = 1.0;
SI[12] = 1.0;
SI[13] = 1.0;
SI[14] = 1.0;
SI[15] = 1.0;
SI[16] = 1.0;
SI[17] = 1.0;
SI[18] = 1.0;
SI[19] = 1.0;
SI[20] = 1.0;
SI[21] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
}