Location: VPH-MIP case study on CellML @ a29bfba242e7 / experiments / model-validation.xml

Author:
David Nickerson <nickerso@users.sourceforge.net>
Date:
2012-08-28 16:59:24+12:00
Desc:
replacing CellML simulation metadata with CSim summary description; bubbling up membrane currents and potential to allow output/referencing via SED-ML.
Permanent Source URI:
http://models.cellml.org/w/andre/VPH-MIP/rawfile/a29bfba242e747b82657c6d2d782937d0a01be79/experiments/model-validation.xml

<?xml version="1.0" encoding="iso-8859-1"?>
<rdf:RDF
        xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
        xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
        xmlns:bqs="http://www.cellml.org/bqs/1.0#"
        xmlns:dc="http://purl.org/dc/elements/1.1/"
        xmlns:dcterms="http://purl.org/dc/terms/"
        xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#"
        xmlns:cs="http://www.cellml.org/metadata/simulation/1.0#"
        xmlns:cg="http://www.cellml.org/metadata/graphs/1.0#">
  <rdf:Description rdf:ID="andre">
    <vCard:N rdf:parseType="Resource">
      <vCard:Family>Nickerson</vCard:Family>
      <vCard:Given>David</vCard:Given>
    </vCard:N>
    <vCard:EMAIL rdf:parseType="Resource">
      <rdf:value>david.nickerson@nus.edu.sg</rdf:value>
      <rdf:type rdf:resource="http://imc.org/vCard/3.0#internet"/>
    </vCard:EMAIL>
    <vCard:ORG rdf:parseType="Resource">
      <vCard:Orgname>National University of Singapore</vCard:Orgname>
      <vCard:Orgunit>Division of Bioengineering</vCard:Orgunit>
    </vCard:ORG>
  </rdf:Description>
  <rdf:Description rdf:about="">
    <dc:creator rdf:resource="#andre"/>
    <dcterms:created rdf:parseType="Resource">
      <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
    </dcterms:created>
    <dc:publisher>
      Division of Bioengineering, National University of Singapore
    </dc:publisher>
    <cmeta:comment rdf:parseType="Resource">
      <rdf:value>
        This document contains all the graphing metadata combined into a single document. I'm pretty sure there is a better way to assemble such a document from the indivual source documents...
      </rdf:value>
    </cmeta:comment>
  </rdf:Description>
  <rdf:Description>
    <cg:graph>
      <rdf:Description rdf:ID="IK-gating-rates">
        <cg:title>IK Gating Rates</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding cg:title property to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-16</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 4 of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>V (mV)</cg:x-label>
        <cg:y-label>Rate constant (ms^-1)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>alpha_n</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="IK-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="IK-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="IK-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="../components/IK.xml#alpha_n"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>beta_n</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="IK-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="IK-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="IK-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="../components/IK.xml#beta_n"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="IK-gating-SS">
        <cg:title>IK Steady State Gating Kinetics</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 5 of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>V (mV)</cg:x-label>
        <cg:y-label>Steady state gate ()</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>n_inf</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="IK-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="IK-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="IK-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="IK-gating-kinetics.xml#n_inf"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="INa-gating-rates">
        <cg:title>INa Gating Rates</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figures 7 and 9 of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>V (mV)</cg:x-label>
        <cg:y-label>Rate constant (ms^-1)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>alpha_m</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#alpha_m"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>beta_m</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#V"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">5.0</cg:maximum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#beta_m"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>alpha_h</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#008000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#alpha_h"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>beta_h</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#808000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#beta_h"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="INa-gating-SS">
        <cg:title>INa Steady State Gating Kinetics</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figures 8 and 10 of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>V (mV)</cg:x-label>
        <cg:y-label>Steady state gate ()</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>m_inf</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#m_inf"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>h_inf</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#V"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="INa-gating-kinetics.xml#simulation"/>
              <cg:variable rdf:resource="INa-gating-kinetics.xml#h_inf"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="voltage-clamp-currents-1">
        <cg:title>Voltage Clamp</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 11(a,b) of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-5 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-005.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">20</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-2</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-005.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>-10 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-010.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">20</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-2</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-010.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="voltage-clamp-currents-2">
        <cg:title>Voltage Clamp</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 11(c) of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-20 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-020.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">20</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-2</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-020.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="voltage-clamp-currents-3">
        <cg:title>Voltage Clamp</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 11(d) of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-30 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-030.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">20</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-2</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-030.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="voltage-clamp-currents-4">
        <cg:title>Voltage Clamp</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 11(e,f) of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-40 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-040.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">8</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-1</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-040.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>-60 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-060.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">8</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-1</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-060.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="voltage-clamp-currents-5">
        <cg:title>Voltage Clamp</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph matches Figure 11(g-j) of the Hodgkin &amp; Huxley (1952) article.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-80 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-080.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">8</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-1</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-080.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>-100 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-100.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">8</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-1</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-100.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>-115 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#008000</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-115.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">8</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-1</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-115.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>-130 mV</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#800080</cg:colour>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-130.xml#simulation"/>
              <cg:variable rdf:resource="voltage-clamp.xml#time"/>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">8</cg:maximum>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">-1</cg:minimum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="voltage-clamp-130.xml#simulation"/>
              <cg:variable rdf:resource="../components/voltage-clamp.xml#I"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="potential">
        <cg:title>Action Potentials</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph illustrates the action potentials simulated using the Hodgkin &amp; Huxley (1952) squid axon model with a periodic electrical stimulus current applied.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Potential (mV)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-V</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/stimulated.xml#minus_V"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="currents">
        <cg:title>Membrane Currents</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph illustrates the membrane currents simulated using the Hodgkin &amp; Huxley (1952) squid axon model with a periodic electrical stimulus current applied.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>INa</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#INa"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>IK</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/IK.xml#IK"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>Ileak</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#008000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/Ileak.xml#Ileak"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="gates">
        <cg:title>Gating Variables</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph illustrates the gating variables simulated using the Hodgkin &amp; Huxley (1952) squid axon model with a periodic electrical stimulus current applied.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Gate value ()</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>n</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/IK.xml#n"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>m</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#m"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>h</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#008000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#h"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="potential-zoom">
        <cg:title>Action Potential</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph illustrates the action potentials simulated using the Hodgkin &amp; Huxley (1952) squid axon model with a periodic electrical stimulus current applied. Here we restrict the view of the time domain in order to better see an individual action potential.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Potential (mV)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>-V</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">95</cg:minimum>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">120</cg:maximum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/stimulated.xml#minus_V"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="currents-zoom">
        <cg:title>Membrane Currents</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph illustrates the membrane currents simulated using the Hodgkin &amp; Huxley (1952) squid axon model with a periodic electrical stimulus current applied. Here we restrict the view of the time domain in order to better see the currents underlying an individual action potential.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
          <bqs:Pubmed_id>12991237</bqs:Pubmed_id>
        </bqs:reference>
        <cmeta:species>loligo</cmeta:species>
        <cmeta:bio_entity>giant nerve fibre</cmeta:bio_entity>
        <cg:x-label>Time (ms)</cg:x-label>
        <cg:y-label>Current (uA.cm^-2)</cg:y-label>
        <cg:background-colour>#ffffff</cg:background-colour>
        <cg:traces rdf:parseType="Collection">
          <rdf:Description>
            <cg:label>INa</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#ff0000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">95</cg:minimum>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">120</cg:maximum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/INa.xml#INa"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>IK</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#0000ff</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">95</cg:minimum>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">120</cg:maximum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/IK.xml#IK"/>
            </cg:y-variable>
          </rdf:Description>
          <rdf:Description>
            <cg:label>Ileak</cg:label>
            <cg:type rdf:resource="http://www.cellml.org/metadata/graphs/1.0#line"/>
            <cg:colour>#008000</cg:colour>
            <cg:line-type rdf:datatype="http://www.w3.org/2001/XMLSchema#integer">1</cg:line-type>
            <cg:x-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="periodic-stimulus.xml#time"/>
              <cg:minimum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">95</cg:minimum>
              <cg:maximum rdf:datatype="http://www.w3.org/2001/XMLSchema#double">120</cg:maximum>
            </cg:x-variable>
            <cg:y-variable rdf:parseType="Resource">
              <cs:simulation rdf:resource="periodic-stimulus.xml#simulation"/>
              <cg:variable rdf:resource="../components/Ileak.xml#Ileak"/>
            </cg:y-variable>
          </rdf:Description>
        </cg:traces>
      </rdf:Description>
    </cg:graph>
    <cg:graph>
      <rdf:Description rdf:ID="gates-zoom">
        <cg:title>Gating Variables</cg:title>
        <cmeta:modification rdf:parseType="Resource">
          <rdf:value>
            Adding more comprehensive metadata to the graph.
          </rdf:value>
          <cmeta:modifier rdf:parseType="Resource">
            <vCard:FN>David Nickerson</vCard:FN>
          </cmeta:modifier>
          <dcterms:modified rdf:parseType="Resource">
            <dcterms:W3CDTF>2008-03-17</dcterms:W3CDTF>
          </dcterms:modified>
        </cmeta:modification>
        <cmeta:comment rdf:parseType="Resource">
          <rdf:value>
            This graph illustrates the gating variables simulated using the Hodgkin &amp; Huxley (1952) squid axon model with a periodic electrical stimulus current applied. Here we restrict the view of the time domain in order to better see the gating transients underlying an individual action potential.
          </rdf:value>
        </cmeta:comment>
        <bqs:reference rdf:parseType="Resource">
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