- Author:
- David Nickerson <nickerso@users.sourceforge.net>
- Date:
- 2017-07-06 16:36:33+12:00
- Desc:
- adding initial versions of the CellML models as published at: http://www.physiome.org.nz/publications/PBMB-2006-90/Nickerson/
- Permanent Source URI:
- http://models.cellml.org/workspace/49e/rawfile/aeb0c953cfd08e3f4649ce2b572fe7bc8ad4e760/experiments/periodic-stimulus.xml
<?xml version="1.0" encoding="iso-8859-1"?>
<model
name="1962_noble-freeRunning"
xmlns="http://www.cellml.org/cellml/1.1#"
xmlns:cellml="http://www.cellml.org/cellml/1.1#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
xmlns:xlink="http://www.w3.org/1999/xlink">
<rdf:RDF
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
xmlns:bqs="http://www.cellml.org/bqs/1.0#"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
<rdf:Description rdf:about="">
<dc:creator rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Nickerson</vCard:Family>
<vCard:Given>David</vCard:Given>
</vCard:N>
<vCard:EMAIL rdf:parseType="Resource">
<rdf:value>d.nickerson@auckland.ac.nz</rdf:value>
<rdf:type rdf:resource="http://imc.org/vCard/3.0#internet" />
</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>The University of Auckland</vCard:Orgname>
<vCard:Orgunit>Bioengineering Institute</vCard:Orgunit>
</vCard:ORG>
</dc:creator>
<dcterms:created rdf:parseType="Resource">
<dcterms:W3CDTF>2004-12-21</dcterms:W3CDTF>
</dcterms:created>
<dc:publisher>
Bioengineering Institute, The University of Auckland.
</dc:publisher>
</rdf:Description>
<rdf:Description rdf:about="#1962_noble-freeRunning">
<dc:title>
Free running version of Noble (1962) Purkinje fibre model
</dc:title>
<cmeta:comment rdf:parseType="Resource">
<rdf:value>
This CellML file describes the boundary conditions used with the
Noble (1962) cardiac Purkinje fibre electrophysiology model to
produce a free running (pacemaker) version of the model.
</rdf:value>
<dc:creator rdf:parseType="Resource">
<vCard:FN>David Nickerson</vCard:FN>
</dc:creator>
</cmeta:comment>
</rdf:Description>
</rdf:RDF>
<import xlink:href="http://www.physiome.org.nz/publications/PBMB-2005-89/Nickerson/models/common/units.xml">
<units name="ms" units_ref="ms"/>
<units name="uA_per_mmsq" units_ref="uA_per_mmsq"/>
<units name="uA_per_mmcu" units_ref="uA_per_mmcu"/>
<units name="mV" units_ref="mV"/>
<units name="mS_per_mmsq" units_ref="mS_per_mmsq"/>
<units name="per_mm" units_ref="per_mm"/>
</import>
<import xlink:href="http://www.physiome.org.nz/publications/PBMB-2005-89/Nickerson/1962_noble.xml">
<component name="model" component_ref="interface"/>
</import>
<component name="time" cmeta:id="time">
<rdf:RDF
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<rdf:Description rdf:about="#stimulus_protocol">
<cmeta:comment rdf:parseType="Resource">
<rdf:value>
The actual definition of the time variable.
</rdf:value>
</cmeta:comment>
</rdf:Description>
</rdf:RDF>
<variable name="time" initial_value="0.0" public_interface="out" units="ms"/>
</component>
<connection>
<map_components component_1="model" component_2="time"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<component name="stimulus_protocol" cmeta:id="stimulus_protocol">
<rdf:RDF
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<rdf:Description rdf:about="#stimulus_protocol">
<cmeta:comment rdf:parseType="Resource">
<rdf:value>
Here we define the stimulus protocol for the simulation.
In this case there is no stimulus applied.
</rdf:value>
</cmeta:comment>
</rdf:Description>
</rdf:RDF>
<variable name="IStim" initial_value="0.0" public_interface="out" units="uA_per_mmsq"/>
<variable name="time" public_interface="in" units="ms"/>
<variable name="stimPeriod" initial_value="750" units="ms"/>
<variable name="stimDuration" initial_value="1" units="ms"/>
<variable name="stimCurrent" initial_value="400" units="uA_per_mmcu"/>
<variable name="Am" initial_value="200" units="per_mm"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply id="stimulus_calculation"><eq />
<ci>IStim</ci>
<piecewise>
<piece>
<apply><divide/>
<ci>stimCurrent</ci>
<ci>Am</ci>
</apply>
<apply><lt/>
<apply><rem/>
<ci>time</ci>
<ci>stimPeriod</ci>
</apply>
<ci>stimDuration</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="uA_per_mmsq">0.0</cn>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<connection>
<map_components component_1="model" component_2="stimulus_protocol"/>
<map_variables variable_1="I_stim" variable_2="IStim"/>
</connection>
<connection>
<map_components component_1="time" component_2="stimulus_protocol"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<component name="parameters" cmeta:id="parameters">
<rdf:RDF
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<rdf:Description rdf:about="#parameters">
<cmeta:comment rdf:parseType="Resource">
<rdf:value>
Here we define the parameter values for this simulation. g_K_add
is used to cancel out the self-activating nature of the model.
</rdf:value>
</cmeta:comment>
</rdf:Description>
</rdf:RDF>
<variable name="g_K_add" initial_value="0.001" public_interface="out" units="mS_per_mmsq"/>
</component>
<connection>
<map_components component_1="model" component_2="parameters"/>
<map_variables variable_1="g_K_add" variable_2="g_K_add"/>
</connection>
</model>
