Location: semantic-annotation @ d31daa83b380 / NaKATPase / NaK_test.cellml

Author:
Dewan Sarwar <sarwarcse@gmail.com>
Date:
2019-02-12 08:57:37+13:00
Desc:
updated Hodgkin and Huxley modelof qualifier
Permanent Source URI:
http://models.cellml.org/workspace/584/rawfile/d31daa83b38087509034d47185f22dfb63ceb919/NaKATPase/NaK_test.cellml

<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:semsim="http://www.bhi.washington.edu/SemSim#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" name="Strieter_1992_NaK" cmeta:id="Strieter_1992_NaK">
  <import xlink:href="Units/Units.cellml">
    <units name="mA_per_cm2" units_ref="mA_per_cm2" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mM" units_ref="mM" />
  </import>
  <import xlink:href="Strieter_1992_NaK.cellml">
    <component name="NaK" component_ref="NaK" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="umol_per_s_per_cm2" units_ref="umol_per_s_per_cm2" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mV" units_ref="mV" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mM_per_s" units_ref="mM_per_s" />
  </import>
  <component name="environment">
    <variable cmeta:id="environment.time" name="time" public_interface="out" units="second" />
  </component>
  <component name="concentrations">
    <variable cmeta:id="concentrations.time" name="time" public_interface="in" units="second" />
    <variable cmeta:id="concentrations.V" initial_value="-150.0" name="V" public_interface="out" units="mV" />
    <variable cmeta:id="concentrations.Na_int" initial_value="10.0" name="Na_int" public_interface="out" units="mM" />
    <variable cmeta:id="concentrations.Na_ext" initial_value="0.001" name="Na_ext" public_interface="out" units="mM" />
    <variable cmeta:id="concentrations.K_int" initial_value="0.001" name="K_int" public_interface="out" units="mM" />
    <variable cmeta:id="concentrations.K_ext" initial_value="50.0" name="K_ext" public_interface="out" units="mM" />
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply>
        <eq />
        <apply>
          <diff />
          <bvar>
            <ci>time</ci>
          </bvar>
          <ci>Na_int</ci>
        </apply>
        <cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" cellml:units="mM_per_s">1</cn>
      </apply>
    </math>
  </component>
  <component name="fluxes">
    <variable cmeta:id="fluxes.J_NaK" name="J_NaK" public_interface="in" units="dimensionless" />
    <variable cmeta:id="fluxes.J_NaK_max" initial_value="0.0108" name="J_NaK_max" public_interface="out" units="umol_per_s_per_cm2" />
    <variable cmeta:id="fluxes.I_NaK" name="I_NaK" public_interface="in" units="mA_per_cm2" />
  </component>
  <connection>
    <map_components component_1="environment" component_2="concentrations" />
    <map_variables variable_1="time" variable_2="time" />
  </connection>
  <connection>
    <map_components component_1="concentrations" component_2="NaK" />
    <map_variables variable_1="K_int" variable_2="K_int" />
    <map_variables variable_1="Na_ext" variable_2="Na_ext" />
    <map_variables variable_1="K_ext" variable_2="K_ext" />
    <map_variables variable_1="V" variable_2="V" />
    <map_variables variable_1="Na_int" variable_2="Na_int" />
  </connection>
  <connection>
    <map_components component_1="NaK" component_2="fluxes" />
    <map_variables variable_1="I_NaK" variable_2="I_NaK" />
    <map_variables variable_1="J_NaK" variable_2="J_NaK" />
  </connection>
  <connection>
    <map_components component_1="fluxes" component_2="NaK" />
    <map_variables variable_1="J_NaK_max" variable_2="J_NaK_max" />
  </connection>
  <rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" xmlns:opb="http://bhi.washington.edu/OPB#" xmlns:j.0="http://imc.org/vCard/3.0#">
    <rdf:Description rdf:about="">
      <dc:creator rdf:parseType="Resource">
        <vCard:N vCard:Family="Terkildsen" vCard:Given="Jonna" />
        <vCard:EMAIL rdf:value="j.terkildsen@auckland.ac.nz" rdf:type="http://imc.org/vCard/3.0#internet" />
        <vCard:ORG rdf:parseType="Resource">
          <vCard:Orgname>Auckland Bioengineering Institute</vCard:Orgname>
        </vCard:ORG>
      </dc:creator>
      <dcterms:created dcterms:W3CDTF="2009-11-11" />
    </rdf:Description>
    <rdf:Description rdf:about="#weinstein_2000_AE1">
      <dc:title>The Weinstein 2000 quantitative model of AE1 (Cl/HCO3 exchanger).</dc:title>
      <cmeta:comment rdf:parseType="Resource">
        <rdf:value>This is the CellML description of the Weinstein 2000 quantitative model of AE1 (Cl/HCO3 exchanger)</rdf:value>
        <dc:creator rdf:parseType="Resource">
          <vCard:FN>Jonna Terkildsen</vCard:FN>
        </dc:creator>
      </cmeta:comment>
      <bqs:reference rdf:parseType="Resource">
        <dc:subject rdf:parseType="Resource">
          <bqs:subject_type>keyword</bqs:subject_type>
          <rdf:value>
            <rdf:Bag>
              <rdf:li>renal</rdf:li>
              <rdf:li>ion transport</rdf:li>
              <rdf:li>kidney</rdf:li>
              <rdf:li>medullary collecting duct</rdf:li>
            </rdf:Bag>
          </rdf:value>
        </dc:subject>
      </bqs:reference>
      <bqs:reference rdf:parseType="Resource">
        <bqs:Pubmed_id>10894785</bqs:Pubmed_id>
        <bqs:JournalArticle rdf:parseType="Resource">
          <dc:creator>
            <rdf:Seq>
              <rdf:li rdf:parseType="Resource">
                <bqs:Person rdf:parseType="Resource">
                  <vCard:N vCard:Family="Weinstein" vCard:Given="A" vCard:Other="M" />
                </bqs:Person>
              </rdf:li>
            </rdf:Seq>
          </dc:creator>
          <dc:title>A mathematical model of the outer medullary collecting duct of the rat</dc:title>
          <dcterms:issued dcterms:W3CDTF="2000-07" />
          <bqs:Journal rdf:parseType="Resource">
            <dc:title>American Journal of Physiology</dc:title>
          </bqs:Journal>
          <bqs:volume>279</bqs:volume>
          <bqs:first_page>24</bqs:first_page>
          <bqs:last_page>45</bqs:last_page>
        </bqs:JournalArticle>
      </bqs:reference>
    </rdf:Description>
    <rdf:Description rdf:about="#Strieter_1992_NaK" semsim:PubMedIDofReferencePublication="10894785" semsim:modelId="Strieter_1992_NaK" semsim:modelName="Strieter_1992_NaK" />
  </rdf:RDF>
</model>