Location: semantic-annotation @ d31daa83b380 / Strieter_1992_NaK.cellml

Author:
Dewan Sarwar <sarwarcse@gmail.com>
Date:
2019-02-12 08:57:37+13:00
Desc:
updated Hodgkin and Huxley modelof qualifier
Permanent Source URI:
http://models.cellml.org/workspace/584/rawfile/d31daa83b38087509034d47185f22dfb63ceb919/Strieter_1992_NaK.cellml

<?xml version="1.0" encoding="UTF-8"?>
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  <import xlink:href="Units/Units.cellml">
    <units name="umol_per_s_per_cm2" units_ref="umol_per_s_per_cm2" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="C_per_mol" units_ref="C_per_mol" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mM" units_ref="mM" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mV" units_ref="mV" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mJ_per_mol_per_kelvin" units_ref="mJ_per_mol_per_kelvin" />
  </import>
  <import xlink:href="Units/Units.cellml">
    <units name="mA_per_cm2" units_ref="mA_per_cm2" />
  </import>
  <component name="NaK">
    <variable cmeta:id="NaK.V" name="V" public_interface="in" units="mV" />
    <variable cmeta:id="NaK.Na_int" name="Na_int" public_interface="in" units="mM" />
    <variable cmeta:id="NaK.Na_ext" name="Na_ext" public_interface="in" units="mM" />
    <variable cmeta:id="NaK.K_int" name="K_int" public_interface="in" units="mM" />
    <variable cmeta:id="NaK.K_ext" name="K_ext" public_interface="in" units="mM" />
    <variable cmeta:id="NaK.K_mNa" initial_value="13" name="K_mNa" units="mM" />
    <variable cmeta:id="NaK.K_mK" initial_value="1" name="K_mK" units="mM" />
    <variable cmeta:id="NaK.sigma" name="sigma" units="dimensionless" />
    <variable cmeta:id="NaK.f_1" name="f_1" units="dimensionless" />
    <variable cmeta:id="NaK.F" initial_value="96485" name="F" units="C_per_mol" />
    <variable cmeta:id="NaK.R" initial_value="8314.41" name="R" units="mJ_per_mol_per_kelvin" />
    <variable cmeta:id="NaK.T" initial_value="300" name="T" units="kelvin" />
    <variable cmeta:id="NaK.J_NaK_max" name="J_NaK_max" public_interface="in" units="umol_per_s_per_cm2" />
    <variable cmeta:id="NaK.J_NaK" name="J_NaK" public_interface="out" units="umol_per_s_per_cm2" />
    <variable cmeta:id="NaK.I_NaK" name="I_NaK" public_interface="out" units="mA_per_cm2" />
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        <eq />
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          <times />
          <apply>
            <divide />
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            <cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" cellml:units="dimensionless">7</cn>
          </apply>
          <apply>
            <minus />
            <apply>
              <exp />
              <apply>
                <divide />
                <ci>Na_ext</ci>
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            </apply>
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                      <minus />
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                  <apply>
                    <times />
                    <ci>R</ci>
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                </apply>
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            <apply>
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                    <times />
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            <minus />
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      </apply>
      <apply>
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        <ci>J_NaK</ci>
        <apply>
          <times />
          <ci>J_NaK_max</ci>
          <apply>
            <power />
            <apply>
              <divide />
              <ci>Na_int</ci>
              <apply>
                <plus />
                <ci>Na_int</ci>
                <ci>K_mNa</ci>
              </apply>
            </apply>
            <cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" cellml:units="dimensionless">3</cn>
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          <apply>
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            <apply>
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              <ci>K_ext</ci>
              <apply>
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            <cn xmlns:cellml="http://www.cellml.org/cellml/1.1#" cellml:units="dimensionless">2</cn>
          </apply>
        </apply>
      </apply>
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          <times />
          <ci>f_1</ci>
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          <ci>J_NaK</ci>
        </apply>
      </apply>
    </math>
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      <dc:title>A kinetic model of Na+/K+-ATPase (sodium-potassium pump)</dc:title>
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      <semsim:isComputationalComponentFor>
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    </rdf:Description>
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        <dc:subject rdf:parseType="Resource">
          <bqs:subject_type>keyword</bqs:subject_type>
          <rdf:value>
            <rdf:Bag>
              <rdf:li>protein module</rdf:li>
            </rdf:Bag>
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