Location: Calcium Dynamics Annotations @ 110f9ba31e34 / noble_noble_2001 / model / noble_noble_2001.rdf

Author:

neilstephen2001 <npar276@aucklanduni.ac.nz>

Date:

2021-01-24 21:37:35+13:00

Desc:

adding OMEX archives to workspace

Permanent Source URI:

http://models.cellml.org/workspace/7f1/rawfile/110f9ba31e34b7499c8d02e13a6b9984351c0e8f/noble_noble_2001/model/noble_noble_2001.rdf

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bqmodel="http://biomodels.net/model-qualifiers/"
    xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.beta_xr2">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_m_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.K_i">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_3">
        <bqbiol:isPartOf>
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            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:226050"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>slow delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.i_b_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_m_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.Ca_up">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_7">
        <bqbiol:isPartOf rdf:resource="./noble_noble_2001.cellml#entity_4"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in uptake site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.xr2">
    <dcterms:description>rapid delayed rectifier potassium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.Cm">
    <dcterms:description>membrane capacitance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.xr1">
    <dcterms:description>rapid delayed rectifier potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.VoltDep">
    <dcterms:description>voltage dependence of calcium release</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.V_i">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_10">
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:226050"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cytosolic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.g_tos">
    <dcterms:description>transient outward current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_h_gate.shift_h">
    <dcterms:description>shift potential of fast sodium current inactivation gate</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.i_Ca_L_Na_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current.g_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>fast sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_Ca_L_Ca_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.K_m_Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for calcium release from domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_translocation_i_trans">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium transfer flux from the network sarcoplasmic reticulum to the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_up_ratio">
    <dcterms:description>volume ratio of uptake site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.i_Ca_L_K_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.P_CaNa">
    <dcterms:description>maximum L-type calcium channel sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.g_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>time-independent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Ca_up">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in uptake site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current_xs_gate.alpha_xs">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_potassium_pump_i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_h_gate.alpha_h">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.d">
    <dcterms:description>L-type calcium channel activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_ds_ratio">
    <dcterms:description>volume ratio of domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.f">
    <dcterms:description>L-type calcium channel inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.Na_o">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_2">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_1">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:70022"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.stim_duration">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_potassium_pump.K_mNa">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_5">
        <bqbiol:isPartOf rdf:resource="./noble_noble_2001.cellml#entity_4"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>sodium half-saturation constant for sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.K_cyca">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>half-saturation constant of calcium binding to cytosolic enzymes</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ca_L_K_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_r_gate.r">
    <dcterms:description>transient outward current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ca_L_Na_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_potassium_pump.K_o">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_0">
        <bqbiol:isPartOf rdf:resource="./noble_noble_2001.cellml#entity_1"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_up">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux into sarcoplasmic reticulum through SERCA pumps</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.i_p_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>persistent sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.Kmdsinact">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant of inactivated L-type calcium channel in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current.E_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>slow potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release_i_rel">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux out of sarcoplasmic reticulum through ryanodine receptors</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.i_Ca_L_Ca_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_s_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.i_Ca_L_Ca_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_background_current.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.alpha_Trop">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.i_Ca_L_K_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_Ca_L_K_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_r_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_potassium_pump.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_NaCa_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_b_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current_i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_potassium_pump.i_NaK_max">
    <dcterms:description>maximum sodium-potassium pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_d_gate.d">
    <dcterms:description>L-type calcium channel activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>slow delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.PrecFrac">
    <dcterms:description>precursor fraction</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_m_gate.alpha_m">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.beta_xr1">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.length">
    <dcterms:description>cell length</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.r">
    <dcterms:description>transient outward current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.stim_amplitude">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00318"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_potassium_pump.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_rel">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux out of sarcoplasmic reticulum through ryanodine receptors</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_rel_ratio">
    <dcterms:description>volume ratio of release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.alpha_up">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.E_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>calcium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.alpha_xr1">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.i_NaCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Kr">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>rapid delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current_xs_gate.xs">
    <dcterms:description>slow potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_background_current.E_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>calcium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_m_gate.m">
    <dcterms:description>fast sodium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current_xs_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.i_Ca_L_Na_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_trans">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium transfer flux from the network sarcoplasmic reticulum to the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Ca_Trop">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_12">
        <bqbiol:isPartOf rdf:resource="./noble_noble_2001.cellml#entity_10"/>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62338"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium-bound troponin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.CaChoffcyt">
    <dcterms:description>fraction of channels with calcium-bound regulatory site in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.i_Ca_L_Na_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.alpha_f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#persistent_sodium_current_i_p_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>persistent sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.k_NaCa">
    <dcterms:description>maximum sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_background_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_background_current_i_b_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Kdecay">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_background_current.g_bna">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>sodium background current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current.E_mh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fast sodium current H-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#environment_time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.Ca_o">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_6">
        <bqbiol:isPartOf rdf:resource="./noble_noble_2001.cellml#entity_1"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.radius">
    <dcterms:description>cell radius</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.P_CaK">
    <dcterms:description>maximum L-type calcium channel potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.Kmdsinact">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant of inactivated L-type calcium channel in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ca_L_Ca_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.s">
    <dcterms:description>transient outward current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.stim_end">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_NaCa_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.K_xcs">
    <dcterms:description>rate of calcium transfer between cytosol and sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.CaChoffds">
    <dcterms:description>fraction of channels with calcium-bound regulatory site in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_d_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration_Calmod">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_11">
        <bqbiol:isPartOf rdf:resource="./noble_noble_2001.cellml#entity_10"/>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62343"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.alpha_Calmod">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.InactRate">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.K_leak_rate">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.beta_up">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_translocation.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.E0_f">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>L-type calcium current F-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_i_ratio">
    <dcterms:description>volume ratio of cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ca_L_Ca_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.ProdFrac">
    <dcterms:description>product fraction</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current.xs">
    <dcterms:description>slow potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.CaChoncyt">
    <dcterms:description>fraction of channels inactivated by voltage-dependent process in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.K_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_3"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.stim_start">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#persistent_sodium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current.g_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>slow delayed rectifier potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_b_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.beta_f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#persistent_sodium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.CaiReg">
    <dcterms:description>regulatory intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.E_mh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fast sodium current H-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.beta_Calmod">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_e_ratio">
    <dcterms:description>volume ratio of endoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_translocation.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_p_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>persistent sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_r_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.g_Kr1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>rapid delayed rectifier potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sarcoplasmic_reticulum_calcium_pump.K_srca">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_8">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_9">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62390"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>half-saturation constant of calcium binding to sarcoplasmic reticulum enzymes</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current_i_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>slow delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current.m">
    <dcterms:description>fast sodium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.g_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>transient outward current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_background_current_i_b_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_background_current.g_bca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>calcium background current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.Na_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.V_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cytosolic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.Ca_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_d_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_b_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_d_gate.alpha_d">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.E_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>slow potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_Cell">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_noble_2001.cellml#entity_13">
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:67196"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cell volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ca_L_K_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.g_Kr2">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>rapid delayed rectifier potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_s_gate.alpha_s">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.n_NaCa">
    <dcterms:description>cooperativity parameter of sodium-calcium exchanger</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.i_Ca_L_Ca_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.KCaChoff">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>half-saturation constant of calcium-bound L-type calcium channel</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.V_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_10"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cytosolic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.CaChonds">
    <dcterms:description>fraction of channels inactivated by voltage-dependent process in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_i_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_sodium_concentration.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#slow_delayed_rectifier_potassium_current_xs_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.P_Ca_L">
    <dcterms:description>maximum L-type calcium channel calcium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.i_NaCa_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_d_gate.E0_d">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>L-type calcium current D-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_m_gate.E0_m">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fast sodium current M-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.delta_f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration_Trop">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_12"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of troponin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_i_Ca_L">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>total L-type calcium channel current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#reversal_potentials.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_background_current.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.V">
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    <dcterms:description>membrane potential</dcterms:description>
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    <dcterms:description>regulatory domains calcium</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
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    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.CaChoncyt">
    <dcterms:description>fraction of channels inactivated by voltage-dependent process in cytosol</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
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    <dcterms:description>fraction of channels inactivated by voltage-dependent process in domains</dcterms:description>
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    <dcterms:description>rapid delayed rectifier potassium current</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_background_current.time">
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_background_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.K_mk1">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for time-independent potassium current</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Stim">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00318"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.K_m_rel">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_translocation.Ca_up">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in uptake site</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.Ca_i">
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in cytosol</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.Na_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#extracellular_calcium_concentration.Ca_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#sodium_calcium_exchanger.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_s_gate.beta_s">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_h_gate.h">
    <dcterms:description>fast sodium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#time_independent_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.xr2">
    <dcterms:description>rapid delayed rectifier potassium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_h_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.beta_Trop">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_Ca_L_K_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in cytosol</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#transient_outward_current_s_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current.h">
    <dcterms:description>fast sodium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_calcium_concentration.Ca_Calmod">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_11"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium-bound calmodulin</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#extracellular_sodium_concentration.Na_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_h_gate.beta_h">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#noble_noble_2001"
     semsim:modelName="noble_noble_2001">
    <semsim:hasCellMLdocumentation>&lt;documentation xmlns="http://cellml.org/tmp-documentation"&gt;&#xD;
  &lt;article&gt;&#xD;
    &lt;articleinfo&gt;&#xD;
      &lt;title&gt;Noble Ventricular Cell Model 1998&lt;/title&gt;&#xD;
      &lt;author&gt;&#xD;
        &lt;firstname&gt;Penny&lt;/firstname&gt;&#xD;
        &lt;surname&gt;Noble&lt;/surname&gt;&#xD;
        &lt;affiliation&gt;&#xD;
          &lt;shortaffil&gt;Oxford University&lt;/shortaffil&gt;&#xD;
        &lt;/affiliation&gt;&#xD;
      &lt;/author&gt;&#xD;
    &lt;/articleinfo&gt;&#xD;
    &lt;section id="sec_status"&gt;&#xD;
      &lt;title&gt;Model Status&lt;/title&gt;&#xD;
      &lt;para&gt;This version of the model has been curated and unit checked and is known to run in PCEnv, COR and Jsim. A PCEnv session file is also available for this model.&lt;/para&gt;&#xD;
    &lt;/section&gt;&#xD;
    &lt;sect1 id="sec_structure"&gt;&#xD;
      &lt;title&gt;Model Structure&lt;/title&gt;&#xD;
      &lt;para&gt;The Noble98 (Noble et al. 1998) model of the guinea-pig ventricular cell was a development of the Noble91 (Noble et al. 1991) model and included representation of the components of IK, (IKr and IKs), the persistent sodium current and a dyadic space between the sarcolemma and the sarcoplasmic reticulum. In several important respects this model was a major improvement on the earlier model. However on rigorous testing for new applications problems associated with the calcium dynamics equations were found in the new model. &#xD;
The model demonstrated here is an attempt at 'correcting' the inability of Noble98 to reproduce a mechanism of initiation of Early After-Depolarizations (EADs), the voltage-dependence of calcium release from the sarcoplasmic reticulum (SR) and also to improve the shape of the calcium transient.&lt;/para&gt;&#xD;
      &lt;informalfigure float="0" id="fig_reaction_diagram"&gt;&#xD;
        &lt;mediaobject&gt;&#xD;
          &lt;imageobject&gt;&#xD;
            &lt;objectinfo&gt;&#xD;
              &lt;title&gt;model diagram&lt;/title&gt;&#xD;
            &lt;/objectinfo&gt;&#xD;
            &lt;imagedata fileref="noble_2001.png" /&gt;&#xD;
          &lt;/imageobject&gt;&#xD;
        &lt;/mediaobject&gt;&#xD;
        &lt;caption&gt;Schematic diagram of the cell model.&lt;/caption&gt;&#xD;
      &lt;/informalfigure&gt;&#xD;
    &lt;/sect1&gt;&#xD;
  &lt;/article&gt;&#xD;
&lt;/documentation&gt;</semsim:hasCellMLdocumentation>
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    <dcterms:description>fast sodium current</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_background_current.V">
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    <dcterms:description>membrane potential</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#intracellular_potassium_concentration.i_Kr">
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#L_type_Ca_channel_f_gate.KCaChoff">
    <bqbiol:isPropertyOf rdf:resource="./noble_noble_2001.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#membrane.i_Ca_L_Na_ds">
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#rapid_delayed_rectifier_potassium_current.xr1">
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#calcium_release.ActFrac">
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  <rdf:Description rdf:about="./noble_noble_2001.cellml#fast_sodium_current_m_gate.delta_m">
    <dcterms:description>saturation potential of fast sodium current activation gate</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
</rdf:RDF>