Location: Calcium Dynamics Annotations @ 629d77f02876 / noble_varghese_kohl_noble_1998_c / model / noble_varghese_kohl_noble_1998_c.rdf

Author:

neilstephen2001 <npar276@aucklanduni.ac.nz>

Date:

2021-01-25 22:22:21+13:00

Desc:

modifying composite annotations

Permanent Source URI:

http://models.cellml.org/workspace/7f1/rawfile/629d77f02876098d987c9f59e66a4b6a87bdff87/noble_varghese_kohl_noble_1998_c/model/noble_varghese_kohl_noble_1998_c.rdf

<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bqmodel="http://biomodels.net/model-qualifiers/"
    xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.i_Ca_L_Na_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#environment_time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_h_gate.alpha_h">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger_i_NaCa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_s_gate.beta_s">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.E_An_stretch">
    <dcterms:description>stretch-dependent current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.Na_i">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_5">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_4">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:226050"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.radius">
    <dcterms:description>cell radius</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.i_Ca_L_Ca_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.i_Ca_L_Na_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.Ca_i">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_7">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_background_current.g_bna">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>sodium background current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.g_fibro_stretch">
    <dcterms:description>stretch-dependent fibroblast current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.alpha_xr1">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.isometric_tension">
    <dcterms:description>isometric tension</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2ds_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.k_NaCa">
    <dcterms:description>maximum sodium-calcium exchanger current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_i_Ca_L">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>total L-type calcium channel current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_i_Kr">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>rapid delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_background_current.g_bca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>calcium background current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current.E_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>slow potassium current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.K_o">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_0">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_1">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:70022"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ATP_dependent_potassium_current.g_K_ATP">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>ATP-sensitive potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current.m">
    <dcterms:description>fast sodium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.E_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>calcium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_K_ACh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>acetylcholine-dependent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump.K_cyca">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>half-saturation constant of calcium binding to cytosolic enzymes</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_m_gate.beta_m">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#persistent_sodium_current.g_pna">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>persistent sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current_i_K_ACh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>acetylcholine-dependent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.g_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>time-independent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.P_CaK">
    <dcterms:description>maximum L-type calcium channel potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_d_gate.alpha_d">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#extracellular_calcium_concentration.Ca_o">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_6">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_1"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.g_tos">
    <dcterms:description>transient outward current conductance </dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_potassium_pump_i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.Ca_Calmod">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_12">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62343"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium-bound calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ATP_dependent_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_background_current_i_b_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_b_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_s_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>slow delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.K_m_rel">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Km_f2">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant of L-type calcium channel</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.ProdFrac">
    <dcterms:description>product fraction</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.cross_bridge_availability">
    <dcterms:description>cross bridge availability</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2ds_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2ds_gate.R_decay">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.g_Ca_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>stretch-dependent calcium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration_K_i">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_3">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.beta_xr1">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_translocation.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.E_mh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fast sodium current H-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump.K_srca">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_10">
        <bqbiol:isPartOf>
          <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_11">
            <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62390"/>
          </rdf:Description>
        </bqbiol:isPartOf>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>half-saturation constant of calcium binding to sarcoplasmic reticulum enzymes</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Ca_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.x_ACh">
    <dcterms:description>acetylcholine-dependent potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_h_gate.h">
    <dcterms:description>fast sodium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.i_Ca_L_K_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.Calmod">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_12"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_rel">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux out of sarcoplasmic reticulum through ryanodine receptors</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current_xACh_gate.beta_ACh">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.CadsReg">
    <dcterms:description>regulatory domains calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current.xr1">
    <dcterms:description>rapid delayed rectifier potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current_i_An_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>stretch-dependent current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump.K_2">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.P_Ca_L">
    <dcterms:description>maximum L-type calcium channel calcium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ATP_dependent_potassium_current_i_K_ATP">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>ATP-sensitive potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_Kr">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>rapid delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Ca_Calmod">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_12"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium-bound calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.g_fibro">
    <dcterms:description>fibroblast current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_potassium_pump.K_mNa">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>sodium half-saturation constant for sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_Ca_L_K_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump.beta_up">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_potassium_pump.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_d_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#persistent_sodium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_b_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_potassium_pump.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_background_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.beta_xr2">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.V_i_ratio">
    <dcterms:description>volume ratio of cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.Na_o">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_2">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_1"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_i_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_background_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.K_leak_rate">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Ca_L_K_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_background_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f_gate.beta_f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_up">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux into sarcoplasmic reticulum through SERCA pumps</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current_xs_gate.xs">
    <dcterms:description>slow potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.f">
    <dcterms:description>L-type calcium channel inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_m_gate.E0_m">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fast sodium current M-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.g_KACh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>acetylcholine-dependent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Ca_L_Na_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_r_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current.xr2">
    <dcterms:description>rapid delayed rectifier potassium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.n_NaCa">
    <dcterms:description>cooperativity parameter of sodium-calcium exchanger</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.g_K_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>stretch-dependent potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.V_ds_ratio">
    <dcterms:description>volume ratio of domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_m_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.Na_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.isometric_tension">
    <dcterms:description>isometric tension</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.Cm">
    <dcterms:description>membrane capacitance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#persistent_sodium_current.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release_i_rel">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux out of sarcoplasmic reticulum through ryanodine receptors</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.KCont3">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.ActRate">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.Na_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.stim_end">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.stim_amplitude">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00318"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_h_gate.beta_h">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.V_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cytosolic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.Ca_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_6"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ATP_dependent_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.InactRate">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_background_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#persistent_sodium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2ds_gate.f2ds">
    <dcterms:description>L-type calcium channel inactivation variable in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current_xACh_gate.alpha_ACh">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.d">
    <dcterms:description>L-type calcium channel activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.i_fibro">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fibroblast current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_K_ATP">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>ATP-sensitive potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.KCont4">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.K_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_3"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.c_fibro">
    <dcterms:description>fibroblast capacitance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Km_f2ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant of L-type calcium channel in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.overlap">
    <dcterms:description>overlapping cross bridge chains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_translocation.Ca_up">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in uptake site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.SRLeak">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ATP_dependent_potassium_current.K_ATP">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for ATP</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.KCont1">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.sarcomere_length">
    <dcterms:description>sarcomere length</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Ca_Trop">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_13">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62338"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium-bound troponin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.K_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_3"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>transient outward current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.Trop">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_13"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of troponin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.s">
    <dcterms:description>transient outward current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.KCont2">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ATP_dependent_potassium_current.ATP">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_8">
        <bqbiol:isPartOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:15422"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of ATP</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2_gate.f2">
    <dcterms:description>L-type calcium channel inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2ds_gate.Km_f2ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant of L-type calcium channel in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_background_current.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Na_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Ca_L_Na_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.xr2">
    <dcterms:description>rapid delayed rectifier potassium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.g_An_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>stretch-dependent current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.beta_Calmod">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_NaCa_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_p_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>persistent sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current_i_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>slow delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_Ca_L_Ca_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.length">
    <dcterms:description>cell length</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_translocation_i_trans">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium transfer flux from the network sarcoplasmic reticulum to the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump_i_up">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium flux into sarcoplasmic reticulum through SERCA pumps</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2_gate.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_m_gate.alpha_m">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current_xs_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane_V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.K_mk1">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_Ca_L_K_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current_i_K_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>stretch-dependent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.K_m_Ca_cyt">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for calcium release from cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_m_gate.m">
    <dcterms:description>fast sodium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Calmod">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_12"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.R_decay">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.E_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>calcium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_Ca_L_Ca_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_Ca_L_Na_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_m_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_background_current_i_b_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.i_Ca_L_Ca_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.sarcomere_length">
    <dcterms:description>sarcomere length</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.V_Cell">
    <bqbiol:isPropertyOf>
      <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#entity_14">
        <bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:67196"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cell volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current_xACh_gate.x_ACh">
    <dcterms:description>acetylcholine-dependent potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.E_fibro_stretch">
    <dcterms:description>stretch-dependent fibroblast current reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_b_Ca">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>calcium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration_Ca_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_translocation.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.r">
    <dcterms:description>transient outward current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr1_gate.xr1">
    <dcterms:description>rapid delayed rectifier potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current.K_D">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for acetylcholine</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.i_Ca_L_K_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_NaCa_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Ca_L_Ca_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel calcium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f_gate.delta_f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.ActFrac">
    <dcterms:description>activator fraction</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_r_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.VoltDep">
    <dcterms:description>voltage dependence of calcium release</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.V_rel_ratio">
    <dcterms:description>volume ratio of release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current_i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.K_mk1">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current_xs_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.tension_rest">
    <dcterms:description>tension during rest</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.tension_active">
    <dcterms:description>tension during active contraction</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.R">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.RegBindSite">
    <dcterms:description>regulatory calcium binding site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Ca_up">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in uptake site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sarcoplasmic_reticulum_calcium_pump.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current.E_mh">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fast sodium current H-gate reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_h_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Ca_rel">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in release site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current_i_KNa">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-activated potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2ds_gate.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_r_gate.r">
    <dcterms:description>transient outward current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_NaCa_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_potassium_pump.i_NaK_max">
    <dcterms:description>maximum sodium-potassium pump current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#persistent_sodium_current_i_p_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>persistent sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.stim_duration">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_s_gate.alpha_s">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current.g_Kr2">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>rapid delayed rectifier potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.sarcomere_length">
    <dcterms:description>sarcomere length</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current_s_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_d_gate.E0_d">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>L-type calcium current D-gate reversal potential</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular calcium</dcterms:description>
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    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00318"/>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
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    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in uptake site</dcterms:description>
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    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of intracellular sodium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current_xr2_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
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    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_13"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of troponin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.E_Ks">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>slow potassium current reversal potential</dcterms:description>
  </rdf:Description>
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    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_2"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular sodium</dcterms:description>
  </rdf:Description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>rapid delayed rectifier potassium current conductance</dcterms:description>
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        <bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:15355"/>
      </rdf:Description>
    </bqbiol:isPropertyOf>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of acetylcholine</dcterms:description>
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    <dcterms:description>L-type calcium channel inactivation variable in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f_gate.alpha_f">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.cross_bridge">
    <dcterms:description>cross bridge</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.CaiReg">
    <dcterms:description>regulatory intracellular calcium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.PrecFrac">
    <dcterms:description>precursor fraction</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current.xs">
    <dcterms:description>slow potassium current activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_d_gate.d">
    <dcterms:description>L-type calcium channel activation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Ca_L_K_cyt">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel potassium current in cytosol</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current_i_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>total stretch-dependent current</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>stretch-dependent sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.XCont1">
    <dcterms:description>ratio of calcium-bound to total troponin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_Kr">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>rapid delayed rectifier potassium current</dcterms:description>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#extracellular_potassium_concentration.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2_gate.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.XCont2">
    <dcterms:description>ratio of calcium-bound to total calmodulin</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.V_e_ratio">
    <dcterms:description>volume ratio of endoplasmic reticulum</dcterms:description>
  </rdf:Description>
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    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>potassium half-saturation constant for sodium-potassium pump</dcterms:description>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_K1">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>time-independent potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.E_K">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>potassium reversal potential</dcterms:description>
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  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f_gate.E0_f">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>L-type calcium current F-gate reversal potential</dcterms:description>
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    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>slow delayed rectifier potassium current</dcterms:description>
  </rdf:Description>
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     semsim:modelName="noble_varghese_kohl_noble_1998_stretch"
     bqmodel:isDescribedBy="9487284">
    <semsim:hasCellMLdocumentation>&lt;documentation xmlns="http://cellml.org/tmp-documentation"&gt;&#xD;
  &lt;article&gt;&#xD;
    &lt;articleinfo&gt;&#xD;
      &lt;title&gt;Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes8&lt;/title&gt;&#xD;
      &lt;author&gt;&#xD;
        &lt;firstname&gt;Catherine&lt;/firstname&gt;&#xD;
        &lt;surname&gt;Lloyd&lt;/surname&gt;&#xD;
        &lt;affiliation&gt;&#xD;
          &lt;shortaffil&gt;Auckland Bioengineering Institute, The University of Auckland&lt;/shortaffil&gt;&#xD;
        &lt;/affiliation&gt;&#xD;
      &lt;/author&gt;&#xD;
    &lt;/articleinfo&gt;&#xD;
    &lt;section id="sec_status"&gt;&#xD;
      &lt;title&gt;Model Status&lt;/title&gt;&#xD;
      &lt;para&gt;This version has been curated and unit-checked by Penny Noble and is known to run in COR and PCEnv. This variant is the STRETCH model, which includes acetylcholine dependent modulation and the electromechanical processes simulated by the extended basic model, and also includes simulation of stretch and fibroblasts. This model is parameterised the same as the BASIC model, with all additional variables set to zero.&lt;/para&gt;&#xD;
    &lt;/section&gt;&#xD;
    &lt;sect1 id="sec_structure"&gt;&#xD;
      &lt;title&gt;Model Structure&lt;/title&gt;&#xD;
      &lt;para&gt;ABSTRACT: The guinea-pig ventricular cell model, originally developed by Noble et al in 1991, has been greatly extended to include accumulation and depletion of calcium in a diadic space between the sarcolemma and the sarcoplasmic reticulum where, according to contempory understanding, the majority of calcium-induced calcium release is triggered. The calcium in this space is also assumed to play the major role in calcium-induced inactivation of the calcium current. Delayed potassium current equations have been developed to include the rapid (IKr) and slow (IKs) components of the delayed rectifier current based on the data of of Heath and Terrar, along with data from Sanguinetti and Jurkiewicz. Length- and tension-dependent changes in mechanical and electrophysiological processes have been incorporated as described recently by Kohl et al. Drug receptor interactions have started to be developed, using the sodium channel as the first target. The new model has been tested against experimental data on action potential clamp, and on force-interval and duration-interval relations; it has been found to reliably reproduce experimental observations.&lt;/para&gt;&#xD;
      &lt;para&gt;The original paper reference is cited below:&lt;/para&gt;&#xD;
      &lt;para&gt;&#xD;
        Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes, Denis Noble, Anthony Varghese, Peter Kohl and Penelope Noble, 1998,&#xD;
        &lt;emphasis&gt;Can J Cardiol&lt;/emphasis&gt;&#xD;
        , 14, 123-134.&#xD;
        &lt;ulink url="http://www.ncbi.nlm.nih.gov/pubmed/9487284"&gt;PubMed ID: 9487284&lt;/ulink&gt;&#xD;
      &lt;/para&gt;&#xD;
      &lt;informalfigure float="0" id="fig_cell_diagram"&gt;&#xD;
        &lt;mediaobject&gt;&#xD;
          &lt;imageobject&gt;&#xD;
            &lt;objectinfo&gt;&#xD;
              &lt;title&gt;cell diagram of Noble'98 model showing ionic currents, pumps and exchangers within the sarcolemma and the sarcoplasmic reticulum&lt;/title&gt;&#xD;
            &lt;/objectinfo&gt;&#xD;
            &lt;imagedata fileref="noble_1998c.png" /&gt;&#xD;
          &lt;/imageobject&gt;&#xD;
        &lt;/mediaobject&gt;&#xD;
        &lt;caption&gt;A schematic diagram describing the current flows across the cell membrane that are captured in the Noble'98 model.&lt;/caption&gt;&#xD;
      &lt;/informalfigure&gt;&#xD;
    &lt;/sect1&gt;&#xD;
  &lt;/article&gt;&#xD;
&lt;/documentation&gt;</semsim:hasCellMLdocumentation>
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    <dcterms:description>stretch-dependent sodium current</dcterms:description>
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    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
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    <dcterms:description>slow delayed rectifier potassium current conductance</dcterms:description>
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    <dcterms:description>rate of calcium transfer between cytosol and sarcoplasmic reticulum</dcterms:description>
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    <dcterms:description>fibroblast junction current conductance</dcterms:description>
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    <dcterms:description>cytosolic volume</dcterms:description>
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    <dcterms:description>transient outward current inactivation variable</dcterms:description>
  </rdf:Description>
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    <dcterms:description>calcium reversal potential</dcterms:description>
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    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_13"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of calcium-bound troponin</dcterms:description>
  </rdf:Description>
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  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.T">
    <dcterms:description>absolute temperature</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.V_i">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_4"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
    <dcterms:description>cytosolic volume</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current.g_K_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>sodium-activated potassium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_activated_potassium_current.K_kna">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_5"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>sodium half-saturation constant for sodium-activated potassium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.cross_bridge_density">
    <dcterms:description>cross bridge density</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.i_NaK">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-potassium pump</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#transient_outward_current.g_to">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>transient outward current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.light_chain">
    <dcterms:description>light cross bridge chains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#stretch_current_i_Ca_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>stretch-dependent calcium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.V_up_ratio">
    <dcterms:description>volume ratio of uptake site</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#contraction.isometric_tension">
    <dcterms:description>isometric tension</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current.g_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00041"/>
    <dcterms:description>fast sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_potassium_concentration.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.stim_start">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#slow_delayed_rectifier_potassium_current_xs_gate.alpha_xs">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#ACh_dependent_potassium_current_xACh_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current.h">
    <dcterms:description>fast sodium current inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_b_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium background current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#time_independent_potassium_current.K_o">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_0"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>concentration of extracellular potassium</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.P_CaNa">
    <dcterms:description>maximum L-type calcium channel sodium current conductance</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.stim_period">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.i_fibro_junct">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fibroblast junction current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.V_fibro">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>fibroblast potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.i_stretch">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>total stretch-dependent current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.i_trans">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00592"/>
    <dcterms:description>calcium transfer flux from the network sarcoplasmic reticulum to the junctional sarcoplasmic reticulum</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>fast sodium current</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.isometric_tension">
    <dcterms:description>isometric tension</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.Kdecay">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#sodium_calcium_exchanger.i_NaCa_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>sodium-calcium exchanger current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_sodium_concentration.i_Ca_L_Na_ds">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
    <dcterms:description>L-type calcium channel sodium current in domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#membrane.F">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel.f2">
    <dcterms:description>L-type calcium channel inactivation variable</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#L_type_Ca_channel_f2_gate.Km_f2">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant of L-type calcium channel</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#calcium_release.K_m_Ca_ds">
    <bqbiol:isPropertyOf rdf:resource="./noble_varghese_kohl_noble_1998_c.cellml#entity_7"/>
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
    <dcterms:description>calcium half-saturation constant for calcium release from domains</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.KTrop">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#rapid_delayed_rectifier_potassium_current.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.alpha_Calmod">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fast_sodium_current_h_gate.time">
    <bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#intracellular_calcium_concentration.sarcomere_length">
    <dcterms:description>sarcomere length</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#fibroblast.V">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>membrane potential</dcterms:description>
  </rdf:Description>
  <rdf:Description rdf:about="./noble_varghese_kohl_noble_1998_c.cellml#reversal_potentials.E_Na">
    <bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
    <dcterms:description>sodium reversal potential</dcterms:description>
  </rdf:Description>
</rdf:RDF>