- Author:
- neilstephen2001 <npar276@aucklanduni.ac.nz>
- Date:
- 2021-01-24 20:36:00+13:00
- Desc:
- adding OMEX archives to workspace
- Permanent Source URI:
- http://models.cellml.org/workspace/7f1/rawfile/badd70406e83865d500190f4842e0cc057d82ae0/rice_jafri_winslow_2000/model/rice_jafri_winslow_2000.rdf
<rdf:RDF
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:semsim="http://www.bhi.washington.edu/SemSim#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:bqmodel="http://biomodels.net/model-qualifiers/"
xmlns:bqbiol="http://biomodels.net/biology-qualifiers/">
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.k_ltrpn_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium off-rate for troponin low affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.f_01">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.E_CaN">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>calcium reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C0">
<dcterms:description>fraction of closed L-type calcium channels</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.P_C1">
<dcterms:description>fraction of ryanodine receptor channels in state PC1</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.Ko">
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</bqbiol:isPartOf>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.LTRPNCa">
<bqbiol:isPropertyOf>
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</rdf:Description>
</bqbiol:isPartOf>
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</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium-bound troponin low-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.P1">
<dcterms:description>fraction of permissive tropomyosin with 1 cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_background_current.E_NaN">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>sodium reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.HTRPNCa">
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<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium-bound troponin high-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.Cao">
<bqbiol:isPropertyOf>
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</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.j">
<dcterms:description>slow sodium current inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.K_mCSQN">
<bqbiol:isPropertyOf>
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<bqbiol:isPartOf>
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<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62387"/>
</rdf:Description>
</bqbiol:isPartOf>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>calcium half-saturation constant of calsequestrin</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>time-dependent potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.K_mKo">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>potassium half-saturation constant for sodium-potassium pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_ns_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>non-specific calcium-activated calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#cell_geometry.A_cap">
<dcterms:description>capacitive membrane area</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.v1">
<dcterms:description>ryanodine receptor channel flux constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>time-independent potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.k_htrpn_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium on-rate for troponin high affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Ca_SS">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_11">
<bqbiol:isPartOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_3">
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62358"/>
</rdf:Description>
</bqbiol:isPartOf>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in subspace</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.I_ns_Ca">
<dcterms:description>maximum non-specific calcium-activated calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.Force"
dcterms:description="force"/>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.Xi">
<dcterms:description>time-dependent potassium current inactivation gate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.f_12">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>time-dependent potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.n_rb">
<dcterms:description>reverse cooperativity constant for SERCA pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_m_gate.m">
<dcterms:description>sodium current activation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C1">
<dcterms:description>fraction of closed L-type calcium channels</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.O_Ca">
<dcterms:description>fraction of open L-type calcium channels in calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.P_C2">
<dcterms:description>fraction of ryanodine receptor channels in state PC2</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Ki">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_8">
<bqbiol:isPartOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_0"/>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29103"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.P0">
<dcterms:description>fraction of permissive tropomyosin with 0 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.Nao">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_5">
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<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.V_NSR">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_2">
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:67225"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>network sarcoplasmic reticulum volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.K_trop">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.k_htrpn_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium off-rate for troponin high affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.Cao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_10"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.K1_infinity">
<dcterms:description>steady state function of time-independent current activation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.k_a_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>ryanodine receptor PO1 - PC1 rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Nao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_5"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.m">
<dcterms:description>sodium current activation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_ns_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>non-specific calcium-activated potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.J_up">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>SERCA pump calcium flux</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.k_ltrpn_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium on-rate for troponin low affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Pns_Na">
<dcterms:description>non-specific current channel sodium permeability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_NaCa">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sodium-calcium exchanger current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C2">
<dcterms:description>fraction of closed L-type calcium channels</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Cao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_10"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.Force_norm">
<dcterms:description>normal force</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_NaCa">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sodium-calcium exchanger current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_NaK">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sodium-potassium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.Cai">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_9">
<bqbiol:isPartOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_0"/>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel_y_gate.y_infinity">
<dcterms:description>steady state function of L-type calcium channel inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.g_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_01300"/>
<dcterms:description>time-independent current conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.J_xfer">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>calcium flux from subspace to myoplasm</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>L-type calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_Xi_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.O">
<dcterms:description>fraction of open L-type calcium channels</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.i_ns_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>non-specific calcium-activated calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.alpha">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.LTRPNCa">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium-bound troponin low-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.P1">
<dcterms:description>fraction of permissive tropomyosin with 1 cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.g_XB_SL">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.Ca_JSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_14"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in junctional sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C3">
<dcterms:description>fraction of closed L-type calcium channels</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_Kp">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>plateau potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_Ca_b">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>background calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.Nao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_5"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.Ca_NSR">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_12">
<bqbiol:isPartOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_2"/>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29108"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in network sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.g_Kp">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_01300"/>
<dcterms:description>maximum plateau potassium channel conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.K_trop_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel_y_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sarcolemmal_calcium_pump.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.Force_norm">
<dcterms:description>normal force</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.X">
<dcterms:description>time-dependent potassium current activation gate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.V_myo">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_0"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>myoplasmic volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.i_Ca_half">
<dcterms:description>calcium current at half potassium permeability of L-type calcium channel</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.P2">
<dcterms:description>fraction of permissive tropomyosin with 2 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.V_SS">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_3"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>subspace volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.N1">
<dcterms:description>fraction of non-permissive tropomyosin with 1 cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.i_Ca_max">
<dcterms:description>calcium current at maximum potassium permeability of L-type calcium channel</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.a">
<dcterms:description>L-type calcium channel mode transition parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_j_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C4">
<dcterms:description>fraction of closed L-type calcium channels</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.HTRPN_tot">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of troponin high-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Ca_NSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_12"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in network sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.beta_b">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.f_NaK">
<dcterms:description>activation curve of sodium-potassium pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.P2_max">
<dcterms:description>maximum fraction of permissive tropomyosin with 2 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.SL">
<dcterms:description>sarcomere length</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.K_mNa">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_4">
<bqbiol:isPartOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_0"/>
<bqbiol:is rdf:resource="https://identifiers.org/chebi/CHEBI:29101"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>sodium half-saturation constant for sodium-calcium exchange</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.K_mNai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>sodium half-saturation constant for sodium-potassium pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.P3">
<dcterms:description>fraction of permissive tropomyosin with 3 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.LTRPNCa">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium-bound troponin low-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.N0">
<dcterms:description>fraction of non-permissive tropomyosin with 0 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.b">
<dcterms:description>L-type calcium channel mode transition parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current_K1_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.g_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_01300"/>
<dcterms:description>time-dependent potassium current conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.J_rel">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>sarcoplasmic reticulum ryanodine receptor calcium release flux</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.Nao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_5"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.P_K">
<dcterms:description>maximum L-type calcium channel permeability to potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.Ca_SS">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_11"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in subspace</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.i_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>L-type calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#environment.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.k_trop_np">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.Ca_SS">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_11"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in subspace</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_X_gate.beta_X">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_X_gate.X">
<dcterms:description>time-dependent potassium current activation gate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.g_23_SL">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.rb">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>reverse calcium flux of SERCA pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.zeta">
<dcterms:description>normalisation conversion factor to physiological force</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_p_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sarcolemmal calcium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.Force_max">
<dcterms:description>maximum force</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.K_m_ns_Ca">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>calcium half-saturation constant for non-specific current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.P3">
<dcterms:description>fraction of permissive tropomyosin with 3 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.J_trpn">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>calcium flux to troponin buffers</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_ns_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>non-specific calcium-activated sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.PNa_K">
<dcterms:description>sodium permeability of time-dependent potassium channel</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.g_">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>transition rate out of open state for calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sarcolemmal_calcium_pump.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.P_O2">
<dcterms:description>fraction of ryanodine receptor channels in state PO2</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.A_cap">
<dcterms:description>capacitive membrane area</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.omega">
<dcterms:description>L-type calcium channel mode transition parameter</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.P_O1">
<dcterms:description>fraction of ryanodine receptor channels in state PO1</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.k_htrpn_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium on-rate for troponin high affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_h_gate.alpha_h">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.h">
<dcterms:description>sodium current inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.Ko">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.Nai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.i_Ca_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>L-type calcium channel potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.N1">
<dcterms:description>fraction of non-permissive tropomyosin with 1 cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current_K1_gate.K1_infinity">
<dcterms:description>steady state function of time-independent current activation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_X_gate.alpha_X">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.Ko">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.P2">
<dcterms:description>fraction of permissive tropomyosin with 2 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.P_O2">
<dcterms:description>fraction of ryanodine receptor channels in state PO2</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.i_ns_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>non-specific calcium-activated potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.P3_max">
<dcterms:description>maximum fraction of permissive tropomyosin with 3 cross bridges</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.SL">
<dcterms:description>sarcomere length</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_Xi_gate.Xi">
<dcterms:description>time-dependent potassium current inactivation gate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.k_rb">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>backward half-saturation constant for calcium ATPase</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.tau_xfer">
<dcterms:description>transfer time constant from subspace to myoplasm</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>fast sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.g_01_SL">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.Ki">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_8"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#cell_geometry.V_JSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_1"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>junctional sarcoplasmic reticulum volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_X_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C_Ca3">
<dcterms:description>fraction of closed L-type calcium channels in calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.J_rel">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>sarcoplasmic reticulum ryanodine receptor calcium release flux</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.f_01">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>fast sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#cell_geometry.V_myo">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_0"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>myoplasmic volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.E_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>time-independent potassium current reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Nai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_Na_b">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>background sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.gamma">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Ko">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.K_mCMDN">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>calcium half-saturation constant of calmodulin</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.f_">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>transition rate into open state for calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.g_12_SL">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.LTRPN_tot">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of troponin low-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.I_NaK">
<dcterms:description>maximum sodium-potassium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Ca_JSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_14"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in junctional sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_m_gate.beta_m">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.n_fb">
<dcterms:description>forward cooperativity constant for SERCA pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.f_12">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel_y_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.f">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>transition rate into open state</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C_Ca2">
<dcterms:description>fraction of closed L-type calcium channels in calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.J_trpn">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>calcium flux to troponin buffers</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_h_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.i_ns_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>non-specific calcium-activated sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.Nai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_NaK">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sodium-potassium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.P_O1">
<dcterms:description>fraction of ryanodine receptor channels in state PO1</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.Cm">
<dcterms:description>membrane capacitance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.k_a_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>ryanodine receptor PC1 - PO1 rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.k_ltrpn_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium on-rate for troponin low affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.HTRPN_tot">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of troponin high-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_Ca_b">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>background calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sarcolemmal_calcium_pump.K_mpCa">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>half-saturation constant for sarcolemmal calcium pump</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.k_b_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>ryanodine receptor PO2 - PO1 rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.g">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>transition rate out of open state</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.k_htrpn_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium off-rate for troponin high affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_j_gate.beta_j">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C_Ca1">
<dcterms:description>fraction of closed L-type calcium channels in calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_j_gate.alpha_j">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.Ko">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.i_Kp">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>plateau potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_Ca_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>L-type calcium channel potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_Xi_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_background_current.E_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>sodium reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current_X_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.g_Na">
<dcterms:description>maximum sodium channel conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.f_XB">
<dcterms:description>basic transition rate from weak to strong cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_p_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sarcolemmal calcium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#cell_geometry.V_NSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_2"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>network sarcoplasmic reticulum volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.p_k">
<dcterms:description>L-type calcium channel permeability to potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C_Ca0">
<dcterms:description>fraction of closed L-type calcium channels in calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_background_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Pns_K">
<dcterms:description>non-specific current channel potassium permeability</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.i_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>time-dependent potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.E_Kp">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>plateau potassium current reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Nao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_5"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sarcolemmal_calcium_pump.I_pCa">
<dcterms:description>maximum sarcolemmal calcium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_h_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.y">
<dcterms:description>L-type calcium channel inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.J_up">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>SERCA pump calcium flux</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.Vmax_f">
<dcterms:description>maximum SERCA forward pumping rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current_K1_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_m_gate.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.alpha_a">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_j_gate.j">
<dcterms:description>slow sodium current inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.k_ltrpn_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium off-rate for troponin low affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.K_trop_half">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.Nai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.k_c_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>ryanodine receptor PO1 - PC2 rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.k_fb">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>forward half-saturation constant for calcium ATPase</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.V_JSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_1"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>junctional sarcoplasmic reticulum volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#cell_geometry.V_SS">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_3"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00154"/>
<dcterms:description>subspace volume</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.Ca_SS">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_11"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in subspace</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.k_sat">
<dcterms:description>sodium-calcium exchange saturation factor at negative potentials</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_h_gate.beta_h">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.g_Cab">
<dcterms:description>maximum background calcium current conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_background_current.g_Nab">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_01300"/>
<dcterms:description>maximum background sodium current conductance</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.n">
<dcterms:description>ryanodine receptor calcium cooperativity parameter PC1 - PO1</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.E_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>time-independent potassium current reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_Na_b">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>background sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.I_ns_Na">
<dcterms:description>maximum non-specific calcium-activated sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sarcolemmal_calcium_pump.i_p_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sarcolemmal calcium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#plateau_potassium_current.Kp">
<dcterms:description>activation curve of plateau potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.LTRPN_tot">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of troponin low-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.E_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>sodium reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.i_Na">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>fast sodium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_h_gate.h">
<dcterms:description>sodium current inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.HTRPNCa">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium-bound troponin high-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Nai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#rice_jafri_winslow_2000_version02"
bqmodel:isDescribedBy="10710361"
semsim:modelName="rice_jafri_winslow_2000_version02">
<semsim:unknown>The Rice et al's 2000 detailed model of ventricular cardiac
myocytes</semsim:unknown>
<semsim:hasCellMLdocumentation><documentation xmlns="http://cellml.org/tmp-documentation">
<article>
<articleinfo>
<title>Modelling Interval-Force Relations in Cardiac Muscle</title>
<author>
<firstname>Catherine</firstname>
<surname>Lloyd</surname>
<affiliation>
<shortaffil>Bioengineering Institute, University of Auckland</shortaffil>
</affiliation>
</author>
</articleinfo>
<section id="sec_status">
<title>Model Status</title>
<para>This is the original unchecked version of the model imported from the previous
CellML model repository, 24-Jan-2006.</para>
</section>
<sect1 id="sec_structure">
<title>Model Structure</title>
<para>
Short-term interval-force (I-F) relations describe the dependence of cardiac muscle contraction strength for short interbeat intervals. Two phenomena that characterise these short-term I-F relations are restitution and postextrasystolic potentiation. In their 2000 paper, J. Jeremy Rice, M. Saleet Jafri and Raimond L. Winslow use two modelling approaches to study short-term interval-force relations in cardiac muscle. Their first approach employs a relatively simple (or minimal), discrete-time model of excitation-contraction coupling. This model explains restitution and postextrasystolic potentiation in terms of the total amount of Ca
<superscript>2+</superscript>
stored in the sarcoplasmic reticulum (SR) and a feature in which Ca
<superscript>2+</superscript>
stored in the SR slowly becomes available for release into the sarcoplasm (see
<xref linkend="fig_simple_diagram" />
below).
</para>
<informalfigure float="0" id="fig_simple_diagram">
<mediaobject>
<imageobject>
<objectinfo>
<title>simple_model</title>
</objectinfo>
<imagedata fileref="rice_2000a.png" />
</imageobject>
<caption>
Schematic diagram of a simple, discrete-time model of Ca
<superscript>2+</superscript>
-handling in restitution and postextrasystolic potentiation. In
<subscript>SC</subscript>
and Out
<subscript>SC</subscript>
represent Ca
<superscript>2+</superscript>
influx and efflux across the sarcolemma, and In
<subscript>SR</subscript>
and Out
<subscript>SR</subscript>
represent sarcoplasmic reticulum Ca
<superscript>2+</superscript>
release and uptake.
</caption>
</mediaobject>
</informalfigure>
<para>
In their second modelling approach, J. Jeremy Rice, M. Saleet Jafri and Raimond L. Winslow develop a more detailed ventricular cell model that is able to simulate action potentials, Ca
<superscript>2+</superscript>
-handling mechanisms, and isometric force generation by the myofilaments. This single comprehensive (or maximal) model combines two previously developed models (see
<ulink url="${HTML_EXMPL_JRW_MODEL}">The Jafri-Rice-Winslow Ventricular Model, 1998</ulink>
and
<ulink url="${HTML_EXMPL_RICE_MODEL}">
Cooperative Mechanisms in Cardiac Muscle, Rice
<emphasis>et al.</emphasis>
, 1999
</ulink>
). The first ventricular cell model describes membrane currents and Ca
<superscript>2+</superscript>
-handling, and the second model of myofilaments provides the force generation of muscle contraction (see
<xref linkend="fig_detailed_diagram" />
below). The ventricular cell model provides the Ca
<superscript>2+</superscript>
needed to drive the myofilament contraction. This is a feedforward pathway in which Ca
<superscript>2+</superscript>
binds to troponin and initiates force generation by triggering myofilament contraction. A feedback pathway also links the two models, as the affinity of troponin for Ca
<superscript>2+</superscript>
is a function of developed force.
</para>
<para>
<ulink url="http://ajpheart.physiology.org/cgi/content/abstract/278/3/H913">Modeling short-term interval-force relations in cardiac muscle</ulink>
J. Jeremy Rice, M. Saleet Jafri and Raimond L. Winslow, 2000,
<ulink url="http://ajpheart.physiology.org/">
<emphasis>American Journal of Physiology</emphasis>
</ulink>
, 278, H913-H931. (
<ulink url="http://ajpheart.physiology.org/cgi/content/full/278/3/H913">Full text</ulink>
and
<ulink url="http://ajpheart.physiology.org/cgi/reprint/278/3/H913.pdf">PDF</ulink>
versions of the article are available for Journal Members on the American Journal of Physiology website.)
<ulink url="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=10710361&amp;dopt=Abstract">PubMed ID: 10710361</ulink>
</para>
<informalfigure float="0" id="fig_detailed_diagram">
<mediaobject>
<imageobject>
<objectinfo>
<title>detailed_model</title>
</objectinfo>
<imagedata fileref="rice_2000b.png" />
</imageobject>
</mediaobject>
<caption>
Schematic diagram of a detailed, single ventricular cell model which is able to simulate action potentials, Ca
<superscript>2+</superscript>
-handling and isometric force generation by myofilaments.
</caption>
</informalfigure>
<para>
Simulation results generated from the model support experimental data. They suggest that short-term interval-force relations result mainly from the interplay between ryanodine receptor adaptation and SR Ca
<superscript>2+</superscript>
loading with additional contributions from membrane currents and myofilament activation.
</para>
</sect1>
</article>
</documentation></semsim:hasCellMLdocumentation>
<semsim:unknown>Cardiac Myocyte</semsim:unknown>
<semsim:modelName>rice_jafri_winslow_2000</semsim:modelName>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.CSQN_tot">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_15">
<bqbiol:isPartOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_1"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62353"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of sarcoplasmic reticulum calsequesterin</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.Ki">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_8"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.g_XB">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>minimum transition rate from strong to weak cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.P1_max">
<dcterms:description>maximum fraction of permissive tropomyosin with 1 cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.P_Ca">
<dcterms:description>L-type calcium channel permeability to calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.m">
<dcterms:description>ryanodine receptor calcium cooperativity parameter PO1 - PO2</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_m_gate.alpha_m">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_background_current.time">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01023"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.Nai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_4"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_Ca">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>L-type calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.i_NaCa">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sodium-calcium exchanger current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.g_XB">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>minimum transition rate from strong to weak cross bridge</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.Cao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_10"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current_K1_gate.alpha_K1">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.J_tr">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>calcium flux from network sarcoplasmic reticulum to junctional sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.Ko">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_7"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.i_Kp">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>plateau potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.k_c_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>ryanodine receptor PC2 - PO1 rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.J_tr">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>calcium flux from network sarcoplasmic reticulum to junctional sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#force_computation.f_23">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.f_23">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_Ca_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>L-type calcium channel potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.eta">
<dcterms:description>voltage dependence factor of sodium-calcium exchange</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.i_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>time-independent potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.LTRPN_tot">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_13"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of troponin low-affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.Cai">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular calcium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.fb">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>SERCA pump forward calcium flux</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.i_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>time-independent potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_ionic_concentrations.CMDN_tot">
<bqbiol:isPropertyOf>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#entity_16">
<bqbiol:isPartOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_0"/>
<bqbiol:is rdf:resource="http://identifiers.org/fma/FMA:62343"/>
</rdf:Description>
</bqbiol:isPropertyOf>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>total concentration of myoplasmic calmodulin</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.i_NaK">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>sodium-potassium pump current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.I_ns_K">
<dcterms:description>maximum non-specific calcium-activated potassium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.J_xfer">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00593"/>
<dcterms:description>calcium flux from subspace to myoplasm</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#calcium_background_current.i_Ca_b">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>background calcium current</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#SERCA_pump.Vmax_r">
<dcterms:description>maximum SERCA reverse pumping rate</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_m_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.C_Ca4">
<dcterms:description>fraction of closed L-type calcium channels in calcium mode</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.tau_tr">
<dcterms:description>transfer time constant from network sarcoplasmic reticulum to junctional sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current_K1_gate.beta_K1">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_independent_potassium_current_K1_gate.E_K1">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>time-independent potassium current reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.Ki">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_8"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#intracellular_Ca_fluxes.Ca_NSR">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_12"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of calcium in network sarcoplasmic reticulum</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current.Nao">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_5"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of extracellular sodium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel_y_gate.y">
<dcterms:description>L-type calcium channel inactivation variable</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_potassium_pump.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.k_NaCa">
<dcterms:description>scaling factor of sodium-calcium exchange</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#RyR_channel_states.k_b_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>ryanodine receptor PO1 - PO2 rate constant</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#fast_sodium_current_j_gate.V">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>membrane potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.k_ltrpn_minus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium off-rate for troponin low affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.Ki">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_8"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>concentration of intracellular potassium</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#non_specific_calcium_activated_current.R">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00410"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel.beta">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#membrane.F">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_00089"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#Na_Ca_exchanger.K_mCa">
<bqbiol:isPropertyOf rdf:resource="./rice_jafri_winslow_2000.cellml#entity_9"/>
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
<dcterms:description>calcium half-saturation constant for sodium-calcium exchange</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#troponin.k_ltrpn_plus">
<bqbiol:is rdf:resource="https://identifiers.org/opb/OPB_01296"/>
<dcterms:description>calcium on-rate for troponin low affinity sites</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.T">
<dcterms:description>absolute temperature</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#tropomyosin_cross_bridges.k_trop_pn">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00340"/>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#time_dependent_potassium_current.E_K">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00506"/>
<dcterms:description>potassium reversal potential</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#L_type_Ca_channel_y_gate.tau_y">
<dcterms:description>inactivation time constant of L-type calcium channel</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="./rice_jafri_winslow_2000.cellml#sodium_background_current.i_Na_b">
<bqbiol:isVersionOf rdf:resource="https://identifiers.org/opb/OPB_00318"/>
<dcterms:description>background sodium current</dcterms:description>
</rdf:Description>
</rdf:RDF>
