- Author:
- Shelley Fong <sfon036@UoA.auckland.ac.nz>
- Date:
- 2022-05-19 14:40:40+12:00
- Desc:
- Removing Ca fluxes between cytosol and SR from this FCU
- Permanent Source URI:
- http://models.cellml.org/workspace/839/rawfile/f4d1e338a31bc1ed2afc4a7f02e12a36c8a18dc7/main_LRd_and_Knk.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="FCU_cardiacAP_composite" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units_and_constants/units_BG.cellml">
<units name="mM" units_ref="mM"/>
<units name="fmol" units_ref="fmol"/>
<units name="per_fmol" units_ref="per_fmol"/>
<units name="J_per_mol" units_ref="J_per_mol"/>
<units name="fmol_per_sec" units_ref="fmol_per_sec"/>
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="J_per_C" units_ref="J_per_C"/>
<units name="microm3" units_ref="microm3"/>
<units name="fF" units_ref="fF"/>
<units name="fC" units_ref="fC"/>
<units name="fA" units_ref="fA"/>
<units name="per_second" units_ref="per_second"/>
<units name="millivolt" units_ref="millivolt"/>
<units name="per_sec" units_ref="per_sec"/>
<units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
<units name="fmol_per_L" units_ref="fmol_per_L"/>
<units name="fmol_per_L_per_sec" units_ref="fmol_per_L_per_sec"/>
<units name="per_sec_per_fmol_per_L" units_ref="per_sec_per_fmol_per_L"/>
<units name="uM" units_ref="uM"/>
<units name="mM_per_sec" units_ref="mM_per_sec"/>
<units name="uM_per_sec" units_ref="uM_per_sec"/>
<units name="pL" units_ref="pL"/>
<units name="m_to_u" units_ref="m_to_u"/>
</import>
<import xlink:href="units_and_constants/constants_BG.cellml">
<component component_ref="constants" name="constants"/>
</import>
<import xlink:href="CaB/BG_CaB.cellml">
<component component_ref="CaB" name="CaB"/>
</import>
<import xlink:href="Ca_leak/BG_Ca_leak.cellml">
<component component_ref="Ca_leak" name="Ca_leak"/>
</import>
<import xlink:href="CMDN_buffer/BG_CMDN_buffer.cellml">
<component component_ref="CMDN_buffer" name="CMDN_buffer"/>
</import>
<import xlink:href="fast_Na/BG_fast_Na.cellml">
<component component_ref="fast_Na" name="fast_Na"/>
</import>
<import xlink:href="K_ATP/BG_K_ATP.cellml">
<component component_ref="K_ATP" name="K_ATP"/>
</import>
<import xlink:href="K1/BG_K1.cellml">
<component component_ref="K1" name="K1"/>
</import>
<import xlink:href="K/BG_K.cellml">
<component component_ref="K" name="K"/>
</import>
<import xlink:href="Kp/BG_Kp.cellml">
<component component_ref="Kp" name="Kp"/>
</import>
<import xlink:href="Kr/BG_Kr.cellml">
<component component_ref="Kr" name="Kr"/>
</import>
<import xlink:href="Ks/BG_Ks.cellml">
<component component_ref="Ks" name="Ks"/>
</import>
<import xlink:href="LCC/BG_LCC.cellml">
<component component_ref="LCC" name="LCC"/>
</import>
<import xlink:href="NaK/BG_NaK.cellml">
<component component_ref="NaK" name="NaK"/>
</import>
<import xlink:href="NaB/BG_NaB.cellml">
<component component_ref="NaB" name="NaB"/>
</import>
<import xlink:href="NCX/BG_NCX.cellml">
<component component_ref="NCX" name="NCX"/>
</import>
<import xlink:href="ns/BG_ns.cellml">
<component component_ref="ns" name="ns"/>
</import>
<import xlink:href="pCa/BG_pCa.cellml">
<component component_ref="pCa" name="pCa"/>
</import>
<import xlink:href="RyR/BG_RyR.cellml">
<component component_ref="RyR" name="RyR"/>
</import>
<import xlink:href="SERCA/BG_SERCA.cellml">
<component component_ref="SERCA" name="SERCA"/>
</import>
<import xlink:href="TCC/BG_TCC.cellml">
<component component_ref="TCC" name="TCC"/>
</import>
<import xlink:href="TO/BG_TO.cellml">
<component component_ref="TO" name="TO"/>
</import>
<import xlink:href="TRPN_buffer/BG_TRPN_buffer.cellml">
<component component_ref="TRPN_buffer" name="TRPN_buffer"/>
</import>
<import xlink:href="funny/BG_funny.cellml">
<component component_ref="funny" name="funny"/>
</import>
<component name="BG_parameters">
<variable initial_value="1039.9" name="kappa_b2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00786813" name="kappa_CaB" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="7.6318e-07" name="kappa_leak" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="10.7176" name="kappa_K1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1125.24" name="kappa_gK1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="219876" name="kappa_Kr" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.51352" name="kappa_xr10" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0672974" name="kappa_xr11" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8.45146" name="kappa_xr20" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="68.9799" name="kappa_xr21" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="12901.2" name="kappa_Ks" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.523159" name="kappa_xs1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.86539" name="kappa_xs2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="3.79696" name="kappa_LCC_Ca1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="4.99924" name="kappa_LCC_Ca2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0110441" name="kappa_LCC_K1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0145411" name="kappa_LCC_K2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="622.118" name="kappa_d000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="31.4169" name="kappa_d010" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="41.3648" name="kappa_d020" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0833323" name="kappa_d001" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00420827" name="kappa_d011" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00554078" name="kappa_d021" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="59.9252" name="kappa_f1_000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="297.574" name="kappa_f1_100" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00802694" name="kappa_f1_001" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0398598" name="kappa_f1_101" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="3.89492" name="kappa_f2_000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="19.3412" name="kappa_f2_100" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.000521722" name="kappa_f2_001" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00259074" name="kappa_f2_101" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8497.95" name="kappa_f3_010" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="42198.7" name="kappa_f3_110" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.13829" name="kappa_f3_011" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="5.65248" name="kappa_f3_111" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="28532.9" name="kappa_fCa000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="141687" name="kappa_fCa100" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1440.9" name="kappa_fCa010" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="7155.17" name="kappa_fCa110" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1897.16" name="kappa_fCa020" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="9420.8" name="kappa_fCa120" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="365655" name="kappa_1_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.6341e+07" name="kappa_2_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="7251.98" name="kappa_3_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.34672e+07" name="kappa_4_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="254618" name="kappa_5_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="5.75477" name="kappa_6_NCX" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00101558" name="kappa_NaB" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="134.008" name="kappa_1_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="299870" name="kappa_2_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.11649e+06" name="kappa_3_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="5.63771e+06" name="kappa_4_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="12276.2" name="kappa_5_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="17.8056" name="kappa_6_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.922004" name="kappa_7_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.90148" name="kappa_8_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1187.34" name="kappa_9_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="390961" name="kappa_10_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="93333.1" name="kappa_11_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="676877" name="kappa_12_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="62.0041" name="kappa_13_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="27.7075" name="kappa_14_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00616157" name="kappa_15_NaK" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.12138e+07" name="kappa_RyR" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8.83262" name="kappa_OC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.12618" name="kappa_CCI" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="883.262" name="kappa_CII" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="73.6052" name="kappa_IO" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.00435e-05" name="kappa_SERCA_R1_2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="68115.9" name="kappa_SERCA_R2_4" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.61158e+06" name="kappa_SERCA_R2_2a" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="66838" name="kappa_SERCA_R4_5" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1828.05" name="kappa_SERCA_R5_6" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="3.44293e+06" name="kappa_SERCA_R6_8" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.72832e+07" name="kappa_SERCA_R8_9" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.6959e+07" name="kappa_SERCA_R9_10" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.00854464" name="kappa_SERCA_R10_1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="35331.7" name="kappa_TCC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1266.14" name="kappa_R1_TCC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="4.33488" name="kappa_R2_TCC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.34962" name="kappa_R3_TCC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="7.44777" name="kappa_R4_TCC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="618.189" name="kappa_b1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="22.9893" name="kappa_Na" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="5.15913e+06" name="kappa_m000" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="1.59606" name="kappa_m001" public_interface="out" units="fmol_per_sec"/>
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<variable initial_value="6.69217e-07" name="kappa_m011" public_interface="out" units="fmol_per_sec"/>
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<variable initial_value="499.427" name="kappa_m101" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="676.886" name="kappa_m110" public_interface="out" units="fmol_per_sec"/>
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<variable initial_value="0.0288559" name="kappa_j310" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0905482" name="kappa_funny_Na" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.000664213" name="kappa_funny_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.188833" name="kappa_R_xf" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="20316.4" name="kappa_pCa_R1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.81725e-05" name="kappa_pCa_R2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_X00_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_X10_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_X01_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_X11_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_i00_K" public_interface="out" units="fmol_per_sec"/>
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<variable initial_value="0" name="kappa_Kp" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_gKp" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_K_ATP" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_ns_Ca" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_ns_Na" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_ns_K" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0" name="kappa_TO" public_interface="out" units="fmol_per_sec"/>
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<variable initial_value="12662.5" name="K_7_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="39059.2" name="K_8_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="1.80537e+07" name="K_9_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="13707.2" name="K_10_NaK" public_interface="out" units="per_fmol"/>
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<variable initial_value="5.74004" name="K_12_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="3.16593" name="K_13_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="0.849044" name="K_14_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="5.01841e+06" name="K_15_NaK" public_interface="out" units="per_fmol"/>
<variable initial_value="11566.7" name="K_MgATP" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000267525" name="K_MgADP" public_interface="out" units="per_fmol"/>
<variable initial_value="0.159075" name="K_Pi" public_interface="out" units="per_fmol"/>
<variable initial_value="2415.19" name="K_H" public_interface="out" units="per_fmol"/>
<variable initial_value="3962.58" name="K_C_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="39.6258" name="K_CI_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="0.06793" name="K_I_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="6.793" name="K_O_RyR" public_interface="out" units="per_fmol"/>
<variable initial_value="29828.4" name="K_P1_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="101542" name="K_P2_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="9917.39" name="K_P2a_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="383852" name="K_P4_SERCA" public_interface="out" units="per_fmol"/>
<variable initial_value="1.37637" name="K_P5_SERCA" public_interface="out" units="per_fmol"/>
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<variable initial_value="0.218009" name="K_TRPN_Ca" public_interface="out" units="per_fmol"/>
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<variable initial_value="1.55065e-05" name="K_100_Na" public_interface="out" units="per_fmol"/>
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<variable initial_value="1e-6" name="K_O_Kp" public_interface="out" units="per_fmol"/>
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<variable initial_value="1e-6" name="K_r1s1_TO" public_interface="out" units="per_fmol"/>
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<variable initial_value="2" name="z_rCa" public_interface="out" units="dimensionless"/>
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<component name="environment">
<variable name="t" public_interface="out" units="second"/>
<variable initial_value="3.71" name="vol_myo" public_interface="out" units="pL"/>
<variable initial_value="60e3" name="C_m" public_interface="out" units="fF"/>
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<variable initial_value="0.911127273" name="q_Ca_o" public_interface="out" units="fmol"/>
<variable initial_value="0.074590321" name="q_Ca_SR" public_interface="out" units="fmol"/>
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<variable initial_value="88.298" name="q_CMDN" public_interface="out" units="fmol"/>
<variable initial_value="0.008904" name="q_CMDN_Ca" public_interface="out" units="fmol"/>
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<variable initial_value="1.82664e-7" name="q_pCa" public_interface="out" units="fmol"/>
<variable initial_value="1.82664e-7" name="q_pCa_Ca" public_interface="out" units="fmol"/>
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<variable initial_value="104.7196316" name="q_TRPN" public_interface="out" units="fmol"/>
<variable initial_value="0.050264642" name="q_TRPN_Ca" public_interface="out" units="fmol"/>
<variable initial_value="-4535.796" name="q_mem" public_interface="out" units="fC"/>
<variable name="V_mem" public_interface="out" units="J_per_C"/>
<!-- channel gate molar amounts-->
<variable initial_value="2.13107e-07" name="q_S00_K" public_interface="out" units="fmol"/>
<variable initial_value="2.13107e-07" name="q_S10_K" public_interface="out" units="fmol"/>
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<variable initial_value="3.65327e-06" name="q_211_Na" public_interface="out" units="fmol"/>
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var q_x1_funny: fmol {init: 9.13318e-07, pub: out};-->
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<apply>
<floor/>
<apply>
<divide/>
<ci>t</ci>
<ci>stimPeriod</ci>
</apply>
</apply>
<ci>stimPeriod</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>I_stim</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">0</cn>
<cn cellml:units="volt">0.075</cn>
<ci>C_m</ci>
</apply>
<ci>stimDuration</ci>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>tPeriod</ci>
<cn cellml:units="second">0.3</cn>
</apply>
<apply>
<leq/>
<ci>tPeriod</ci>
<apply>
<plus/>
<cn cellml:units="second">0.3</cn>
<ci>stimDuration</ci>
</apply>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="fA">0.0</cn>
</otherwise>
</piecewise>
</apply>
</math>
<!-- CaB imports-->
<variable name="v_CaB" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_CaB" public_interface="in" units="fA"/>
<!-- Ca_leak imports-->
<variable name="v_leak" public_interface="in" units="fmol_per_sec"/>
<!-- CMDN_buffer imports-->
<variable name="v_b2" public_interface="in" units="fmol_per_sec"/>
<!-- fast_Na imports-->
<variable name="v_Na" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_Na" public_interface="in" units="fA"/>
<!-- funny imports-->
<variable name="v_funny_K" public_interface="in" units="fmol_per_sec"/>
<variable name="v_funny_Na" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_funny" public_interface="in" units="fA"/>
<!-- K imports-->
<variable name="v_K" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_K" public_interface="in" units="fA"/>
<!-- K_ATP imports-->
<variable name="v_K_ATP" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_K_ATP" public_interface="in" units="fA"/>
<!-- K1 imports-->
<variable name="v_K1" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_K1" public_interface="in" units="fA"/>
<!-- Kp imports-->
<variable name="v_Kp" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_Kp" public_interface="in" units="fA"/>
<!-- Kr imports-->
<variable name="v_Kr" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_Kr" public_interface="in" units="fA"/>
<!-- Ks imports-->
<variable name="v_Ks" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_Ks" public_interface="in" units="fA"/>
<!-- LCC imports-->
<variable name="v_Ca_o_LCC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Ca_i_LCC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_K_o_LCC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_K_i_LCC" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_LCC" public_interface="in" units="fA"/>
<!-- NaK imports-->
<variable name="v_K_o_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_K_i_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Na_o_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Na_i_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_H_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_MgADP_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_MgATP_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Pi_NaK" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_NaK" public_interface="in" units="fA"/>
<!-- NaB imports-->
<variable name="v_NaB" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_NaB" public_interface="in" units="fA"/>
<!-- ns imports-->
<variable name="v_ns_Ca" public_interface="in" units="fmol_per_sec"/>
<variable name="v_ns_Na" public_interface="in" units="fmol_per_sec"/>
<variable name="v_ns_K" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_ns_Ca" public_interface="in" units="fA"/>
<variable name="I_mem_ns_Na" public_interface="in" units="fA"/>
<variable name="I_mem_ns_K" public_interface="in" units="fA"/>
<!-- NCX imports-->
<variable name="v_Ca_o_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Ca_i_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Na_o_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Na_i_NCX" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_NCX" public_interface="in" units="fA"/>
<!-- pCa imports-->
<variable name="v_pCa_R1" public_interface="in" units="fmol_per_sec"/>
<variable name="v_pCa_R2" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_pCa" public_interface="in" units="fA"/>
<!-- RyR imports-->
<variable name="v_RyR" public_interface="in" units="fmol_per_sec"/>
<variable name="v_RyRgate_Ca_i" public_interface="in" units="fmol_per_sec"/>
<!-- SERCA imports-->
<variable name="v_Ca_i_SERCA" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Ca_SR_SERCA" public_interface="in" units="fmol_per_sec"/>
<variable name="v_H_SERCA" public_interface="in" units="fmol_per_sec"/>
<variable name="v_MgADP_SERCA" public_interface="in" units="fmol_per_sec"/>
<variable name="v_MgATP_SERCA" public_interface="in" units="fmol_per_sec"/>
<variable name="v_Pi_SERCA" public_interface="in" units="fmol_per_sec"/>
<!-- TCC imports-->
<variable name="v_TCC" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_TCC" public_interface="in" units="fA"/>
<!-- TO imports-->
<variable name="v_TO" public_interface="in" units="fmol_per_sec"/>
<variable name="I_mem_TO" public_interface="in" units="fA"/>
<!-- TRPN_buffer imports-->
<variable name="v_b1" public_interface="in" units="fmol_per_sec"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Ca_i</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_CaB</ci>
</apply>
<ci>v_leak</ci>
</apply>
<ci>v_b2</ci>
</apply>
<ci>v_Ca_i_LCC</ci>
<ci>v_Ca_i_NCX</ci>
</apply>
<ci>v_pCa_R1</ci>
</apply>
<ci>v_RyR</ci>
<ci>v_RyRgate_Ca_i</ci>
<ci>v_Ca_i_SERCA</ci>
</apply>
<ci>v_TCC</ci>
</apply>
<ci>v_ns_Ca</ci>
</apply>
<ci>v_b1</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Ca_SR</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v_leak</ci>
</apply>
<ci>v_RyR</ci>
</apply>
<ci>v_Ca_SR_SERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_CMDN</ci>
</apply>
<apply>
<minus/>
<ci>v_b2</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_CMDN_Ca</ci>
</apply>
<ci>v_b2</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Na_i</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_Na</ci>
</apply>
<ci>v_Na_i_NaK</ci>
</apply>
<ci>v_NaB</ci>
</apply>
<ci>v_Na_i_NCX</ci>
</apply>
<ci>v_ns_Na</ci>
</apply>
<ci>v_funny_Na</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_K_i</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v_K</ci>
</apply>
<ci>v_K1</ci>
</apply>
<ci>v_Kp</ci>
</apply>
<ci>v_Kr</ci>
</apply>
<ci>v_Ks</ci>
</apply>
<ci>v_K_i_LCC</ci>
<ci>v_K_i_NaK</ci>
</apply>
<ci>v_TO</ci>
</apply>
<ci>v_K_ATP</ci>
</apply>
<ci>v_ns_K</ci>
</apply>
<ci>v_funny_K</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_MgATP</ci>
</apply>
<apply>
<plus/>
<ci>v_MgATP_NaK</ci>
<ci>v_MgATP_SERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_MgADP</ci>
</apply>
<apply>
<plus/>
<ci>v_MgADP_NaK</ci>
<ci>v_MgADP_SERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Pi</ci>
</apply>
<apply>
<plus/>
<ci>v_Pi_NaK</ci>
<ci>v_Pi_SERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_H</ci>
</apply>
<apply>
<plus/>
<ci>v_H_NaK</ci>
<ci>v_H_SERCA</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_pCa</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_pCa_R1</ci>
</apply>
<ci>v_pCa_R2</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_pCa_Ca</ci>
</apply>
<apply>
<minus/>
<ci>v_pCa_R1</ci>
<ci>v_pCa_R2</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_TRPN</ci>
</apply>
<apply>
<minus/>
<ci>v_b1</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_TRPN_Ca</ci>
</apply>
<ci>v_b1</ci>
</apply>
<!-- -->
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Ca_o</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>v_CaB</ci>
<ci>v_Ca_o_LCC</ci>
<ci>v_Ca_o_NCX</ci>
<ci>v_pCa_R2</ci>
<ci>v_TCC</ci>
<ci>v_ns_Ca</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_Na_o</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>v_Na</ci>
<ci>v_Na_o_NaK</ci>
<ci>v_NaB</ci>
<ci>v_Na_o_NCX</ci>
<ci>v_ns_Na</ci>
<ci>v_funny_Na</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_K_o</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>v_K</ci>
<ci>v_K1</ci>
<ci>v_Kp</ci>
<ci>v_Kr</ci>
<ci>v_Ks</ci>
<ci>v_K_o_LCC</ci>
<ci>v_K_o_NaK</ci>
<ci>v_TO</ci>
<ci>v_K_ATP</ci>
<ci>v_ns_K</ci>
<ci>v_funny_K</ci>
</apply>
</apply>
</apply>
<!-- -->
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_mem</ci>
</apply>
<apply>
<plus/>
<ci>I_mem_CaB</ci>
<ci>I_mem_Na</ci>
<ci>I_mem_K</ci>
<ci>I_mem_K_ATP</ci>
<ci>I_mem_K1</ci>
<ci>I_mem_Kp</ci>
<ci>I_mem_Kr</ci>
<ci>I_mem_Ks</ci>
<ci>I_mem_LCC</ci>
<ci>I_mem_NaB</ci>
<ci>I_mem_NaK</ci>
<ci>I_mem_NCX</ci>
<ci>I_mem_ns_Ca</ci>
<ci>I_mem_pCa</ci>
<ci>I_mem_TCC</ci>
<ci>I_mem_TO</ci>
<ci>I_stim</ci>
<ci>I_mem_ns_Na</ci>
<ci>I_mem_ns_K</ci>
<ci>I_mem_funny</ci>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="environment" component_2="CaB"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="v_CaB" variable_2="v_CaB"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="V_mem" variable_2="V_mem"/>
<map_variables variable_1="I_mem_CaB" variable_2="I_mem_CaB"/>
</connection>
<connection>
<map_components component_1="environment" component_2="Ca_leak"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Ca_SR" variable_2="q_Ca_SR"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="v_leak" variable_2="v_leak"/>
</connection>
<connection>
<map_components component_1="environment" component_2="CMDN_buffer"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_CMDN" variable_2="q_CMDN"/>
<map_variables variable_1="q_CMDN_Ca" variable_2="q_CMDN_Ca"/>
<map_variables variable_1="v_b2" variable_2="v_b2"/>
</connection>
<connection>
<map_components component_1="environment" component_2="fast_Na"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_000_Na" variable_2="q_S000_Na"/>
<map_variables variable_1="q_100_Na" variable_2="q_S100_Na"/>
<map_variables variable_1="q_200_Na" variable_2="q_S200_Na"/>
<map_variables variable_1="q_300_Na" variable_2="q_S300_Na"/>
<map_variables variable_1="q_010_Na" variable_2="q_S010_Na"/>
<map_variables variable_1="q_110_Na" variable_2="q_S110_Na"/>
<map_variables variable_1="q_210_Na" variable_2="q_S210_Na"/>
<map_variables variable_1="q_310_Na" variable_2="q_S310_Na"/>
<map_variables variable_1="q_001_Na" variable_2="q_S001_Na"/>
<map_variables variable_1="q_101_Na" variable_2="q_S101_Na"/>
<map_variables variable_1="q_201_Na" variable_2="q_S201_Na"/>
<map_variables variable_1="q_301_Na" variable_2="q_S301_Na"/>
<map_variables variable_1="q_011_Na" variable_2="q_S011_Na"/>
<map_variables variable_1="q_111_Na" variable_2="q_S111_Na"/>
<map_variables variable_1="q_211_Na" variable_2="q_S211_Na"/>
<map_variables variable_1="q_311_Na" variable_2="q_S311_Na"/>
<map_variables variable_1="v_Na" variable_2="v_Na"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_Na" variable_2="I_mem_Na"/>
</connection>
<connection>
<map_components component_1="K" component_2="environment"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_S00_K" variable_2="q_S00_K"/>
<map_variables variable_1="q_S10_K" variable_2="q_S10_K"/>
<map_variables variable_1="q_S20_K" variable_2="q_S20_K"/>
<map_variables variable_1="q_S01_K" variable_2="q_S01_K"/>
<map_variables variable_1="q_S11_K" variable_2="q_S11_K"/>
<map_variables variable_1="q_S21_K" variable_2="q_S21_K"/>
<map_variables variable_1="v_K" variable_2="v_K"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_K" variable_2="I_mem_K"/>
</connection>
<connection>
<map_components component_1="K_ATP" component_2="environment"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="v_K_ATP" variable_2="v_K_ATP"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_K_ATP" variable_2="I_mem_K_ATP"/>
</connection>
<connection>
<map_components component_1="environment" component_2="K1"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_C_K1" variable_2="q_C_K1"/>
<map_variables variable_1="q_O_K1" variable_2="q_O_K1"/>
<map_variables variable_1="v_K1" variable_2="v_K1"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_K1" variable_2="I_mem_K1"/>
</connection>
<connection>
<map_components component_1="environment" component_2="Kp"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_C_Kp" variable_2="q_C_Kp"/>
<map_variables variable_1="q_O_Kp" variable_2="q_O_Kp"/>
<map_variables variable_1="v_Kp" variable_2="v_Kp"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_Kp" variable_2="I_mem_Kp"/>
</connection>
<connection>
<map_components component_1="environment" component_2="Kr"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_Sa_Kr" variable_2="q_Sa"/>
<map_variables variable_1="q_Sb_Kr" variable_2="q_Sb"/>
<map_variables variable_1="q_Sc_Kr" variable_2="q_Sc"/>
<map_variables variable_1="q_Sd_Kr" variable_2="q_Sd"/>
<map_variables variable_1="v_Kr" variable_2="v_Kr"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_Kr" variable_2="I_mem_Kr"/>
</connection>
<connection>
<map_components component_1="environment" component_2="Ks"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_S_Ks0" variable_2="q_S_Ks0"/>
<map_variables variable_1="q_S_Ks1" variable_2="q_S_Ks1"/>
<map_variables variable_1="q_S_Ks2" variable_2="q_S_Ks2"/>
<map_variables variable_1="v_Ks" variable_2="v_Ks"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_Ks" variable_2="I_mem_Ks"/>
</connection>
<connection>
<map_components component_1="environment" component_2="LCC"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_000_LCC" variable_2="q_S000_LCC"/>
<map_variables variable_1="q_010_LCC" variable_2="q_S010_LCC"/>
<map_variables variable_1="q_020_LCC" variable_2="q_S020_LCC"/>
<map_variables variable_1="q_100_LCC" variable_2="q_S100_LCC"/>
<map_variables variable_1="q_110_LCC" variable_2="q_S110_LCC"/>
<map_variables variable_1="q_120_LCC" variable_2="q_S120_LCC"/>
<map_variables variable_1="q_001_LCC" variable_2="q_S001_LCC"/>
<map_variables variable_1="q_011_LCC" variable_2="q_S011_LCC"/>
<map_variables variable_1="q_021_LCC" variable_2="q_S021_LCC"/>
<map_variables variable_1="q_101_LCC" variable_2="q_S101_LCC"/>
<map_variables variable_1="q_111_LCC" variable_2="q_S111_LCC"/>
<map_variables variable_1="q_121_LCC" variable_2="q_S121_LCC"/>
<map_variables variable_1="v_Ca_o_LCC" variable_2="v_Ca_o_LCC"/>
<map_variables variable_1="v_Ca_i_LCC" variable_2="v_Ca_i_LCC"/>
<map_variables variable_1="v_K_o_LCC" variable_2="v_K_o_LCC"/>
<map_variables variable_1="v_K_i_LCC" variable_2="v_K_i_LCC"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_LCC" variable_2="I_mem_LCC"/>
</connection>
<connection>
<map_components component_1="environment" component_2="NaK"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_MgATP" variable_2="q_MgATP"/>
<map_variables variable_1="q_MgADP" variable_2="q_MgADP"/>
<map_variables variable_1="q_Pi" variable_2="q_Pi"/>
<map_variables variable_1="q_H" variable_2="q_H"/>
<map_variables variable_1="q_P7" variable_2="q_P7"/>
<map_variables variable_1="q_P14" variable_2="q_P14"/>
<map_variables variable_1="q_P15" variable_2="q_P15"/>
<map_variables variable_1="q_P1" variable_2="q_P1"/>
<map_variables variable_1="q_P2" variable_2="q_P2"/>
<map_variables variable_1="q_P3" variable_2="q_P3"/>
<map_variables variable_1="q_P4" variable_2="q_P4"/>
<map_variables variable_1="q_P5" variable_2="q_P5"/>
<map_variables variable_1="q_P6" variable_2="q_P6"/>
<map_variables variable_1="q_P10" variable_2="q_P10"/>
<map_variables variable_1="q_P11" variable_2="q_P11"/>
<map_variables variable_1="q_P12" variable_2="q_P12"/>
<map_variables variable_1="q_P13" variable_2="q_P13"/>
<map_variables variable_1="q_P8" variable_2="q_P8"/>
<map_variables variable_1="q_P9" variable_2="q_P9"/>
<map_variables variable_1="v_K_o_NaK" variable_2="v_K_o_NaK"/>
<map_variables variable_1="v_K_i_NaK" variable_2="v_K_i_NaK"/>
<map_variables variable_1="v_Na_o_NaK" variable_2="v_Na_o_NaK"/>
<map_variables variable_1="v_Na_i_NaK" variable_2="v_Na_i_NaK"/>
<map_variables variable_1="v_H_NaK" variable_2="v_H_NaK"/>
<map_variables variable_1="v_MgADP_NaK" variable_2="v_MgADP_NaK"/>
<map_variables variable_1="v_MgATP_NaK" variable_2="v_MgATP_NaK"/>
<map_variables variable_1="v_Pi_NaK" variable_2="v_Pi_NaK"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_NaK" variable_2="I_mem_NaK"/>
</connection>
<connection>
<map_components component_1="environment" component_2="NaB"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="v_NaB" variable_2="v_NaB"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="V_mem" variable_2="V_mem"/>
<map_variables variable_1="I_mem_NaB" variable_2="I_mem_NaB"/>
</connection>
<connection>
<map_components component_1="environment" component_2="NCX"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="q_P1_NCX" variable_2="q_P1_NCX"/>
<map_variables variable_1="q_P2_NCX" variable_2="q_P2_NCX"/>
<map_variables variable_1="q_P3_NCX" variable_2="q_P3_NCX"/>
<map_variables variable_1="q_P4_NCX" variable_2="q_P4_NCX"/>
<map_variables variable_1="q_P5_NCX" variable_2="q_P5_NCX"/>
<map_variables variable_1="q_P6_NCX" variable_2="q_P6_NCX"/>
<map_variables variable_1="v_Ca_o_NCX" variable_2="v_Ca_o_NCX"/>
<map_variables variable_1="v_Ca_i_NCX" variable_2="v_Ca_i_NCX"/>
<map_variables variable_1="v_Na_o_NCX" variable_2="v_Na_o_NCX"/>
<map_variables variable_1="v_Na_i_NCX" variable_2="v_Na_i_NCX"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_NCX" variable_2="I_mem_NCX"/>
</connection>
<connection>
<map_components component_1="environment" component_2="ns"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="v_ns_Ca" variable_2="v_ns_Ca"/>
<map_variables variable_1="I_mem_ns_Ca" variable_2="I_mem_ns_Ca"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="v_ns_Na" variable_2="v_ns_Na"/>
<map_variables variable_1="I_mem_ns_Na" variable_2="I_mem_ns_Na"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="v_ns_K" variable_2="v_ns_K"/>
<map_variables variable_1="I_mem_ns_K" variable_2="I_mem_ns_K"/>
</connection>
<connection>
<map_components component_1="environment" component_2="pCa"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="q_pCa" variable_2="q_pCa"/>
<map_variables variable_1="q_pCa_Ca" variable_2="q_pCa_Ca"/>
<map_variables variable_1="v_pCa_R1" variable_2="v_pCa_R1"/>
<map_variables variable_1="v_pCa_R2" variable_2="v_pCa_R2"/>
<map_variables variable_1="I_mem_pCa" variable_2="I_mem_pCa"/>
</connection>
<connection>
<map_components component_1="environment" component_2="RyR"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Ca_SR" variable_2="q_Ca_SR"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_C_RyR" variable_2="q_C_RyR"/>
<map_variables variable_1="q_CI_RyR" variable_2="q_CI_RyR"/>
<map_variables variable_1="q_I_RyR" variable_2="q_I_RyR"/>
<map_variables variable_1="q_O_RyR" variable_2="q_O_RyR"/>
<map_variables variable_1="v_RyR" variable_2="v_RyR"/>
<map_variables variable_1="v_RyRgate_Ca_i" variable_2="v_RyRgate_Ca_i"/>
</connection>
<connection>
<map_components component_1="environment" component_2="SERCA"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_H" variable_2="q_H"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Ca_SR" variable_2="q_Ca_SR"/>
<map_variables variable_1="q_MgATP" variable_2="q_MgATP"/>
<map_variables variable_1="q_MgADP" variable_2="q_MgADP"/>
<map_variables variable_1="q_Pi" variable_2="q_Pi"/>
<map_variables variable_1="v_Ca_i_SERCA" variable_2="v_Ca_i_SERCA"/>
<map_variables variable_1="v_Ca_SR_SERCA" variable_2="v_Ca_SR_SERCA"/>
<map_variables variable_1="v_H_SERCA" variable_2="v_H_SERCA"/>
<map_variables variable_1="v_MgADP_SERCA" variable_2="v_MgADP_SERCA"/>
<map_variables variable_1="v_MgATP_SERCA" variable_2="v_MgATP_SERCA"/>
<map_variables variable_1="v_Pi_SERCA" variable_2="v_Pi_SERCA"/>
<map_variables variable_1="q_P1_SERCA" variable_2="q_P1_SERCA"/>
<map_variables variable_1="q_P2_SERCA" variable_2="q_P2_SERCA"/>
<map_variables variable_1="q_P2a_SERCA" variable_2="q_P2a_SERCA"/>
<map_variables variable_1="q_P4_SERCA" variable_2="q_P4_SERCA"/>
<map_variables variable_1="q_P5_SERCA" variable_2="q_P5_SERCA"/>
<map_variables variable_1="q_P6_SERCA" variable_2="q_P6_SERCA"/>
<map_variables variable_1="q_P8_SERCA" variable_2="q_P8_SERCA"/>
<map_variables variable_1="q_P9_SERCA" variable_2="q_P9_SERCA"/>
<map_variables variable_1="q_P10_SERCA" variable_2="q_P10_SERCA"/>
</connection>
<connection>
<map_components component_1="environment" component_2="TCC"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_Ca_o" variable_2="q_Ca_o"/>
<map_variables variable_1="q_S00_TCC" variable_2="q_s00_TCC"/>
<map_variables variable_1="q_S10_TCC" variable_2="q_s10_TCC"/>
<map_variables variable_1="q_S01_TCC" variable_2="q_s01_TCC"/>
<map_variables variable_1="q_S11_TCC" variable_2="q_s11_TCC"/>
<map_variables variable_1="v_TCC" variable_2="v_TCC"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_TCC" variable_2="I_mem_TCC"/>
</connection>
<connection>
<map_components component_1="environment" component_2="TO"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_r0s0_TO" variable_2="q_r0s0_TO"/>
<map_variables variable_1="q_r1s0_TO" variable_2="q_r1s0_TO"/>
<map_variables variable_1="q_r0s1_TO" variable_2="q_r0s1_TO"/>
<map_variables variable_1="q_r1s1_TO" variable_2="q_r1s1_TO"/>
<map_variables variable_1="v_TO" variable_2="v_TO"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="I_mem_TO" variable_2="I_mem_TO"/>
</connection>
<connection>
<map_components component_1="environment" component_2="TRPN_buffer"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_Ca_i" variable_2="q_Ca_i"/>
<map_variables variable_1="q_TRPN" variable_2="q_TRPN"/>
<map_variables variable_1="q_TRPN_Ca" variable_2="q_TRPN_Ca"/>
<map_variables variable_1="v_b1" variable_2="v_b1"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="CaB"/>
<map_variables variable_1="kappa_CaB" variable_2="kappa_CaB"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="zCa" variable_2="zCa"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="Ca_leak"/>
<map_variables variable_1="kappa_leak" variable_2="kappa_leak"/>
<map_variables variable_1="K_Ca_SR" variable_2="K_Ca_SR"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="fast_Na"/>
<map_variables variable_1="kappa_Na" variable_2="kappa_Na"/>
<map_variables variable_1="kappa_m000" variable_2="kappa_m000"/>
<map_variables variable_1="kappa_m001" variable_2="kappa_m001"/>
<map_variables variable_1="kappa_m010" variable_2="kappa_m010"/>
<map_variables variable_1="kappa_m011" variable_2="kappa_m011"/>
<map_variables variable_1="kappa_m100" variable_2="kappa_m100"/>
<map_variables variable_1="kappa_m101" variable_2="kappa_m101"/>
<map_variables variable_1="kappa_m110" variable_2="kappa_m110"/>
<map_variables variable_1="kappa_m111" variable_2="kappa_m111"/>
<map_variables variable_1="kappa_m200" variable_2="kappa_m200"/>
<map_variables variable_1="kappa_m201" variable_2="kappa_m201"/>
<map_variables variable_1="kappa_m210" variable_2="kappa_m210"/>
<map_variables variable_1="kappa_m211" variable_2="kappa_m211"/>
<map_variables variable_1="kappa_h000" variable_2="kappa_h000"/>
<map_variables variable_1="kappa_h001" variable_2="kappa_h001"/>
<map_variables variable_1="kappa_h100" variable_2="kappa_h100"/>
<map_variables variable_1="kappa_h101" variable_2="kappa_h101"/>
<map_variables variable_1="kappa_h200" variable_2="kappa_h200"/>
<map_variables variable_1="kappa_h201" variable_2="kappa_h201"/>
<map_variables variable_1="kappa_h300" variable_2="kappa_h300"/>
<map_variables variable_1="kappa_h301" variable_2="kappa_h301"/>
<map_variables variable_1="kappa_j000" variable_2="kappa_j000"/>
<map_variables variable_1="kappa_j010" variable_2="kappa_j010"/>
<map_variables variable_1="kappa_j100" variable_2="kappa_j100"/>
<map_variables variable_1="kappa_j110" variable_2="kappa_j110"/>
<map_variables variable_1="kappa_j200" variable_2="kappa_j200"/>
<map_variables variable_1="kappa_j210" variable_2="kappa_j210"/>
<map_variables variable_1="kappa_j300" variable_2="kappa_j300"/>
<map_variables variable_1="kappa_j310" variable_2="kappa_j310"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_000_Na" variable_2="K_000_Na"/>
<map_variables variable_1="K_100_Na" variable_2="K_100_Na"/>
<map_variables variable_1="K_200_Na" variable_2="K_200_Na"/>
<map_variables variable_1="K_300_Na" variable_2="K_300_Na"/>
<map_variables variable_1="K_010_Na" variable_2="K_010_Na"/>
<map_variables variable_1="K_110_Na" variable_2="K_110_Na"/>
<map_variables variable_1="K_210_Na" variable_2="K_210_Na"/>
<map_variables variable_1="K_310_Na" variable_2="K_310_Na"/>
<map_variables variable_1="K_001_Na" variable_2="K_001_Na"/>
<map_variables variable_1="K_101_Na" variable_2="K_101_Na"/>
<map_variables variable_1="K_201_Na" variable_2="K_201_Na"/>
<map_variables variable_1="K_301_Na" variable_2="K_301_Na"/>
<map_variables variable_1="K_011_Na" variable_2="K_011_Na"/>
<map_variables variable_1="K_111_Na" variable_2="K_111_Na"/>
<map_variables variable_1="K_211_Na" variable_2="K_211_Na"/>
<map_variables variable_1="K_311_Na" variable_2="K_311_Na"/>
<map_variables variable_1="zNa" variable_2="zNa"/>
<map_variables variable_1="z_fh" variable_2="z_fh"/>
<map_variables variable_1="z_fj" variable_2="z_fj"/>
<map_variables variable_1="z_fm" variable_2="z_fm"/>
<map_variables variable_1="z_rh" variable_2="z_rh"/>
<map_variables variable_1="z_rj" variable_2="z_rj"/>
<map_variables variable_1="z_rm" variable_2="z_rm"/>
</connection>
<connection>
<map_components component_1="K" component_2="BG_parameters"/>
<map_variables variable_1="K_S00_K" variable_2="K_S00_K"/>
<map_variables variable_1="K_S01_K" variable_2="K_S01_K"/>
<map_variables variable_1="K_S10_K" variable_2="K_S10_K"/>
<map_variables variable_1="K_S11_K" variable_2="K_S11_K"/>
<map_variables variable_1="K_S20_K" variable_2="K_S20_K"/>
<map_variables variable_1="K_S21_K" variable_2="K_S21_K"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="kappa_K" variable_2="kappa_K"/>
<map_variables variable_1="kappa_X00_K" variable_2="kappa_X00_K"/>
<map_variables variable_1="kappa_X01_K" variable_2="kappa_X01_K"/>
<map_variables variable_1="kappa_X10_K" variable_2="kappa_X10_K"/>
<map_variables variable_1="kappa_X11_K" variable_2="kappa_X11_K"/>
<map_variables variable_1="kappa_i00_K" variable_2="kappa_i00_K"/>
<map_variables variable_1="kappa_i10_K" variable_2="kappa_i10_K"/>
<map_variables variable_1="kappa_i20_K" variable_2="kappa_i20_K"/>
<map_variables variable_1="nK" variable_2="nK"/>
<map_variables variable_1="zK" variable_2="zK"/>
<map_variables variable_1="z_fX" variable_2="z_fX"/>
<map_variables variable_1="z_fXi" variable_2="z_fXi"/>
<map_variables variable_1="z_rX" variable_2="z_rX"/>
<map_variables variable_1="z_rXi" variable_2="z_rXi"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="K1"/>
<map_variables variable_1="kappa_K1" variable_2="kappa_K1"/>
<map_variables variable_1="kappa_gK1" variable_2="kappa_gK1"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_C_K1" variable_2="K_C_K1"/>
<map_variables variable_1="K_O_K1" variable_2="K_O_K1"/>
<map_variables variable_1="z_fK1" variable_2="z_fK1"/>
<map_variables variable_1="z_rK1" variable_2="z_rK1"/>
<map_variables variable_1="nK" variable_2="nK"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="K_ATP" component_2="BG_parameters"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="kappa_K_ATP" variable_2="kappa_K_ATP"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="Kp"/>
<map_variables variable_1="kappa_Kp" variable_2="kappa_Kp"/>
<map_variables variable_1="kappa_gKp" variable_2="kappa_gKp"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_C_Kp" variable_2="K_C_Kp"/>
<map_variables variable_1="K_O_Kp" variable_2="K_O_Kp"/>
<map_variables variable_1="zK" variable_2="zK"/>
<map_variables variable_1="z_f_Kp" variable_2="z_f_Kp"/>
<map_variables variable_1="z_r_Kp" variable_2="z_r_Kp"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="Kr"/>
<map_variables variable_1="kappa_Kr" variable_2="kappa_Kr"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="kappa_xr10" variable_2="kappa_xr10"/>
<map_variables variable_1="kappa_xr11" variable_2="kappa_xr11"/>
<map_variables variable_1="kappa_xr20" variable_2="kappa_xr20"/>
<map_variables variable_1="kappa_xr21" variable_2="kappa_xr21"/>
<map_variables variable_1="K_Sa_Kr" variable_2="K_Sa_Kr"/>
<map_variables variable_1="K_Sb_Kr" variable_2="K_Sb_Kr"/>
<map_variables variable_1="K_Sc_Kr" variable_2="K_Sc_Kr"/>
<map_variables variable_1="K_Sd_Kr" variable_2="K_Sd_Kr"/>
<map_variables variable_1="z_xr1_f" variable_2="z_xr1_f"/>
<map_variables variable_1="z_xr1_r" variable_2="z_xr1_r"/>
<map_variables variable_1="z_xr2_f" variable_2="z_xr2_f"/>
<map_variables variable_1="z_xr2_r" variable_2="z_xr2_r"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="Ks"/>
<map_variables variable_1="kappa_Ks" variable_2="kappa_Ks"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="kappa_xs1" variable_2="kappa_xs1"/>
<map_variables variable_1="kappa_xs2" variable_2="kappa_xs2"/>
<map_variables variable_1="K_S_Ks0" variable_2="K_S_Ks0"/>
<map_variables variable_1="K_S_Ks1" variable_2="K_S_Ks1"/>
<map_variables variable_1="K_S_Ks2" variable_2="K_S_Ks2"/>
<map_variables variable_1="z_xs_f" variable_2="z_xs_f"/>
<map_variables variable_1="z_xs_r" variable_2="z_xs_r"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="LCC"/>
<map_variables variable_1="kappa_LCC_Ca1" variable_2="kappa_LCC_Ca1"/>
<map_variables variable_1="kappa_LCC_Ca2" variable_2="kappa_LCC_Ca2"/>
<map_variables variable_1="kappa_LCC_K1" variable_2="kappa_LCC_K1"/>
<map_variables variable_1="kappa_LCC_K2" variable_2="kappa_LCC_K2"/>
<map_variables variable_1="kappa_d000" variable_2="kappa_d000"/>
<map_variables variable_1="kappa_d010" variable_2="kappa_d010"/>
<map_variables variable_1="kappa_d020" variable_2="kappa_d020"/>
<map_variables variable_1="kappa_d001" variable_2="kappa_d001"/>
<map_variables variable_1="kappa_d011" variable_2="kappa_d011"/>
<map_variables variable_1="kappa_d021" variable_2="kappa_d021"/>
<map_variables variable_1="kappa_f1_000" variable_2="kappa_f1_000"/>
<map_variables variable_1="kappa_f1_100" variable_2="kappa_f1_100"/>
<map_variables variable_1="kappa_f1_001" variable_2="kappa_f1_001"/>
<map_variables variable_1="kappa_f1_101" variable_2="kappa_f1_101"/>
<map_variables variable_1="kappa_f2_000" variable_2="kappa_f2_000"/>
<map_variables variable_1="kappa_f2_100" variable_2="kappa_f2_100"/>
<map_variables variable_1="kappa_f2_001" variable_2="kappa_f2_001"/>
<map_variables variable_1="kappa_f2_101" variable_2="kappa_f2_101"/>
<map_variables variable_1="kappa_f3_010" variable_2="kappa_f3_010"/>
<map_variables variable_1="kappa_f3_110" variable_2="kappa_f3_110"/>
<map_variables variable_1="kappa_f3_011" variable_2="kappa_f3_011"/>
<map_variables variable_1="kappa_f3_111" variable_2="kappa_f3_111"/>
<map_variables variable_1="kappa_fCa000" variable_2="kappa_fCa000"/>
<map_variables variable_1="kappa_fCa100" variable_2="kappa_fCa100"/>
<map_variables variable_1="kappa_fCa010" variable_2="kappa_fCa010"/>
<map_variables variable_1="kappa_fCa110" variable_2="kappa_fCa110"/>
<map_variables variable_1="kappa_fCa020" variable_2="kappa_fCa020"/>
<map_variables variable_1="kappa_fCa120" variable_2="kappa_fCa120"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_000_LCC" variable_2="K_000_LCC"/>
<map_variables variable_1="K_010_LCC" variable_2="K_010_LCC"/>
<map_variables variable_1="K_020_LCC" variable_2="K_020_LCC"/>
<map_variables variable_1="K_100_LCC" variable_2="K_100_LCC"/>
<map_variables variable_1="K_110_LCC" variable_2="K_110_LCC"/>
<map_variables variable_1="K_120_LCC" variable_2="K_120_LCC"/>
<map_variables variable_1="K_001_LCC" variable_2="K_001_LCC"/>
<map_variables variable_1="K_011_LCC" variable_2="K_011_LCC"/>
<map_variables variable_1="K_021_LCC" variable_2="K_021_LCC"/>
<map_variables variable_1="K_101_LCC" variable_2="K_101_LCC"/>
<map_variables variable_1="K_111_LCC" variable_2="K_111_LCC"/>
<map_variables variable_1="K_121_LCC" variable_2="K_121_LCC"/>
<map_variables variable_1="z_rCa" variable_2="z_rCa"/>
<map_variables variable_1="z_fd" variable_2="z_fd"/>
<map_variables variable_1="z_ff1" variable_2="z_ff1"/>
<map_variables variable_1="z_ff2" variable_2="z_ff2"/>
<map_variables variable_1="z_ff3" variable_2="z_ff3"/>
<map_variables variable_1="z_rd" variable_2="z_rd"/>
<map_variables variable_1="z_rf1" variable_2="z_rf1"/>
<map_variables variable_1="z_rf2" variable_2="z_rf2"/>
<map_variables variable_1="z_rf3" variable_2="z_rf3"/>
<map_variables variable_1="zCa" variable_2="zCa"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="NaK"/>
<map_variables variable_1="kappa_1_NaK" variable_2="kappa_1_NaK"/>
<map_variables variable_1="kappa_2_NaK" variable_2="kappa_2_NaK"/>
<map_variables variable_1="kappa_3_NaK" variable_2="kappa_3_NaK"/>
<map_variables variable_1="kappa_4_NaK" variable_2="kappa_4_NaK"/>
<map_variables variable_1="kappa_5_NaK" variable_2="kappa_5_NaK"/>
<map_variables variable_1="kappa_6_NaK" variable_2="kappa_6_NaK"/>
<map_variables variable_1="kappa_7_NaK" variable_2="kappa_7_NaK"/>
<map_variables variable_1="kappa_8_NaK" variable_2="kappa_8_NaK"/>
<map_variables variable_1="kappa_9_NaK" variable_2="kappa_9_NaK"/>
<map_variables variable_1="kappa_10_NaK" variable_2="kappa_10_NaK"/>
<map_variables variable_1="kappa_11_NaK" variable_2="kappa_11_NaK"/>
<map_variables variable_1="kappa_12_NaK" variable_2="kappa_12_NaK"/>
<map_variables variable_1="kappa_13_NaK" variable_2="kappa_13_NaK"/>
<map_variables variable_1="kappa_14_NaK" variable_2="kappa_14_NaK"/>
<map_variables variable_1="kappa_15_NaK" variable_2="kappa_15_NaK"/>
<map_variables variable_1="K_1_NaK" variable_2="K_1_NaK"/>
<map_variables variable_1="K_2_NaK" variable_2="K_2_NaK"/>
<map_variables variable_1="K_3_NaK" variable_2="K_3_NaK"/>
<map_variables variable_1="K_4_NaK" variable_2="K_4_NaK"/>
<map_variables variable_1="K_5_NaK" variable_2="K_5_NaK"/>
<map_variables variable_1="K_6_NaK" variable_2="K_6_NaK"/>
<map_variables variable_1="K_7_NaK" variable_2="K_7_NaK"/>
<map_variables variable_1="K_8_NaK" variable_2="K_8_NaK"/>
<map_variables variable_1="K_9_NaK" variable_2="K_9_NaK"/>
<map_variables variable_1="K_10_NaK" variable_2="K_10_NaK"/>
<map_variables variable_1="K_11_NaK" variable_2="K_11_NaK"/>
<map_variables variable_1="K_12_NaK" variable_2="K_12_NaK"/>
<map_variables variable_1="K_13_NaK" variable_2="K_13_NaK"/>
<map_variables variable_1="K_14_NaK" variable_2="K_14_NaK"/>
<map_variables variable_1="K_15_NaK" variable_2="K_15_NaK"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_MgATP" variable_2="K_MgATP"/>
<map_variables variable_1="K_MgADP" variable_2="K_MgADP"/>
<map_variables variable_1="K_Pi" variable_2="K_Pi"/>
<map_variables variable_1="K_H" variable_2="K_H"/>
<map_variables variable_1="zF_5" variable_2="zF_5"/>
<map_variables variable_1="zF_8" variable_2="zF_8"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="NaB"/>
<map_variables variable_1="kappa_NaB" variable_2="kappa_NaB"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="zNa" variable_2="zNa"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="NCX"/>
<map_variables variable_1="kappa_1_NCX" variable_2="kappa_1_NCX"/>
<map_variables variable_1="kappa_2_NCX" variable_2="kappa_2_NCX"/>
<map_variables variable_1="kappa_3_NCX" variable_2="kappa_3_NCX"/>
<map_variables variable_1="kappa_4_NCX" variable_2="kappa_4_NCX"/>
<map_variables variable_1="kappa_5_NCX" variable_2="kappa_5_NCX"/>
<map_variables variable_1="kappa_6_NCX" variable_2="kappa_6_NCX"/>
<map_variables variable_1="K_1_NCX" variable_2="K_1_NCX"/>
<map_variables variable_1="K_2_NCX" variable_2="K_2_NCX"/>
<map_variables variable_1="K_3_NCX" variable_2="K_3_NCX"/>
<map_variables variable_1="K_4_NCX" variable_2="K_4_NCX"/>
<map_variables variable_1="K_5_NCX" variable_2="K_5_NCX"/>
<map_variables variable_1="K_6_NCX" variable_2="K_6_NCX"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="nNa_o_NCX" variable_2="nNa_o_NCX"/>
<map_variables variable_1="nNa_i_NCX" variable_2="nNa_i_NCX"/>
<map_variables variable_1="zf_NCX" variable_2="zf_NCX"/>
<map_variables variable_1="zr_NCX" variable_2="zr_NCX"/>
</connection>
<connection>
<map_components component_1="ns" component_2="BG_parameters"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="kappa_ns_Ca" variable_2="kappa_ns_Ca"/>
<map_variables variable_1="kappa_ns_Na" variable_2="kappa_ns_Na"/>
<map_variables variable_1="kappa_ns_K" variable_2="kappa_ns_K"/>
<map_variables variable_1="zCa" variable_2="zCa"/>
<map_variables variable_1="zNa" variable_2="zNa"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="pCa"/>
<map_variables variable_1="kappa_pCa_R1" variable_2="kappa_pCa_R1"/>
<map_variables variable_1="kappa_pCa_R2" variable_2="kappa_pCa_R2"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="K_pCa" variable_2="K_pCa"/>
<map_variables variable_1="K_pCa_Ca" variable_2="K_pCa_Ca"/>
<map_variables variable_1="zCa" variable_2="zCa"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="RyR"/>
<map_variables variable_1="kappa_RyR" variable_2="kappa_RyR"/>
<map_variables variable_1="kappa_OC" variable_2="kappa_OC"/>
<map_variables variable_1="kappa_CCI" variable_2="kappa_CCI"/>
<map_variables variable_1="kappa_CII" variable_2="kappa_CII"/>
<map_variables variable_1="kappa_IO" variable_2="kappa_IO"/>
<map_variables variable_1="K_Ca_SR" variable_2="K_Ca_SR"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_C_RyR" variable_2="K_C_RyR"/>
<map_variables variable_1="K_CI_RyR" variable_2="K_CI_RyR"/>
<map_variables variable_1="K_I_RyR" variable_2="K_I_RyR"/>
<map_variables variable_1="K_O_RyR" variable_2="K_O_RyR"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="SERCA"/>
<map_variables variable_1="kappa_SERCA_R1_2" variable_2="kappa_SERCA_R1_2"/>
<map_variables variable_1="kappa_SERCA_R2_4" variable_2="kappa_SERCA_R2_4"/>
<map_variables variable_1="kappa_SERCA_R2_2a" variable_2="kappa_SERCA_R2_2a"/>
<map_variables variable_1="kappa_SERCA_R4_5" variable_2="kappa_SERCA_R4_5"/>
<map_variables variable_1="kappa_SERCA_R5_6" variable_2="kappa_SERCA_R5_6"/>
<map_variables variable_1="kappa_SERCA_R6_8" variable_2="kappa_SERCA_R6_8"/>
<map_variables variable_1="kappa_SERCA_R8_9" variable_2="kappa_SERCA_R8_9"/>
<map_variables variable_1="kappa_SERCA_R9_10" variable_2="kappa_SERCA_R9_10"/>
<map_variables variable_1="kappa_SERCA_R10_1" variable_2="kappa_SERCA_R10_1"/>
<map_variables variable_1="K_P1_SERCA" variable_2="K_P1_SERCA"/>
<map_variables variable_1="K_P2_SERCA" variable_2="K_P2_SERCA"/>
<map_variables variable_1="K_P2a_SERCA" variable_2="K_P2a_SERCA"/>
<map_variables variable_1="K_P4_SERCA" variable_2="K_P4_SERCA"/>
<map_variables variable_1="K_P5_SERCA" variable_2="K_P5_SERCA"/>
<map_variables variable_1="K_P6_SERCA" variable_2="K_P6_SERCA"/>
<map_variables variable_1="K_P8_SERCA" variable_2="K_P8_SERCA"/>
<map_variables variable_1="K_P9_SERCA" variable_2="K_P9_SERCA"/>
<map_variables variable_1="K_P10_SERCA" variable_2="K_P10_SERCA"/>
<map_variables variable_1="K_H" variable_2="K_H"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Ca_SR" variable_2="K_Ca_SR"/>
<map_variables variable_1="K_MgATP" variable_2="K_MgATP"/>
<map_variables variable_1="K_MgADP" variable_2="K_MgADP"/>
<map_variables variable_1="K_Pi" variable_2="K_Pi"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="TCC"/>
<map_variables variable_1="kappa_TCC" variable_2="kappa_TCC"/>
<map_variables variable_1="kappa_R1_TCC" variable_2="kappa_R1_TCC"/>
<map_variables variable_1="kappa_R2_TCC" variable_2="kappa_R2_TCC"/>
<map_variables variable_1="kappa_R3_TCC" variable_2="kappa_R3_TCC"/>
<map_variables variable_1="kappa_R4_TCC" variable_2="kappa_R4_TCC"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_Ca_o" variable_2="K_Ca_o"/>
<map_variables variable_1="K_S00_TCC" variable_2="K_S00_TCC"/>
<map_variables variable_1="K_S10_TCC" variable_2="K_S10_TCC"/>
<map_variables variable_1="K_S01_TCC" variable_2="K_S01_TCC"/>
<map_variables variable_1="K_S11_TCC" variable_2="K_S11_TCC"/>
<map_variables variable_1="z_df" variable_2="z_df"/>
<map_variables variable_1="z_ff" variable_2="z_ff"/>
<map_variables variable_1="z_dr" variable_2="z_dr"/>
<map_variables variable_1="z_fr" variable_2="z_fr"/>
<map_variables variable_1="zCa" variable_2="zCa"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="TO"/>
<map_variables variable_1="kappa_TO" variable_2="kappa_TO"/>
<map_variables variable_1="kappa_gTO_1" variable_2="kappa_gTO_1"/>
<map_variables variable_1="kappa_gTO_2" variable_2="kappa_gTO_2"/>
<map_variables variable_1="kappa_gTO_3" variable_2="kappa_gTO_3"/>
<map_variables variable_1="kappa_gTO_4" variable_2="kappa_gTO_4"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_r0s0_TO" variable_2="K_r0s0_TO"/>
<map_variables variable_1="K_r1s0_TO" variable_2="K_r1s0_TO"/>
<map_variables variable_1="K_r0s1_TO" variable_2="K_r0s1_TO"/>
<map_variables variable_1="K_r1s1_TO" variable_2="K_r1s1_TO"/>
<map_variables variable_1="z_rTO_f" variable_2="z_rTO_f"/>
<map_variables variable_1="z_sTO_f" variable_2="z_sTO_f"/>
<map_variables variable_1="z_rTO_r" variable_2="z_rTO_r"/>
<map_variables variable_1="z_sTO_r" variable_2="z_sTO_r"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="environment" component_2="funny"/>
<map_variables variable_1="t" variable_2="t"/>
<map_variables variable_1="q_K_i" variable_2="q_K_i"/>
<map_variables variable_1="q_K_o" variable_2="q_K_o"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_x0_funny" variable_2="q_x0_funny"/>
<map_variables variable_1="q_x1_funny" variable_2="q_x1_funny"/>
<map_variables variable_1="q_mem" variable_2="q_mem"/>
<map_variables variable_1="C_m" variable_2="C_m"/>
<map_variables variable_1="v_funny_K" variable_2="v_funny_K"/>
<map_variables variable_1="v_funny_Na" variable_2="v_funny_Na"/>
<map_variables variable_1="I_mem_funny" variable_2="I_mem_funny"/>
</connection>
<connection>
<map_components component_1="funny" component_2="BG_parameters"/>
<map_variables variable_1="kappa_funny_Na" variable_2="kappa_funny_Na"/>
<map_variables variable_1="kappa_funny_K" variable_2="kappa_funny_K"/>
<map_variables variable_1="kappa_R_xf" variable_2="kappa_R_xf"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_K_i" variable_2="K_K_i"/>
<map_variables variable_1="K_K_o" variable_2="K_K_o"/>
<map_variables variable_1="K_x0_funny" variable_2="K_x0_funny"/>
<map_variables variable_1="K_x1_funny" variable_2="K_x1_funny"/>
<map_variables variable_1="z_xff" variable_2="z_xff"/>
<map_variables variable_1="z_xfr" variable_2="z_xfr"/>
<map_variables variable_1="zNa" variable_2="zNa"/>
<map_variables variable_1="zK" variable_2="zK"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="TRPN_buffer"/>
<map_variables variable_1="kappa_b1" variable_2="kappa_b1"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_TRPN" variable_2="K_TRPN"/>
<map_variables variable_1="K_TRPN_Ca" variable_2="K_TRPN_Ca"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="CMDN_buffer"/>
<map_variables variable_1="kappa_b2" variable_2="kappa_b2"/>
<map_variables variable_1="K_Ca_i" variable_2="K_Ca_i"/>
<map_variables variable_1="K_CMDN" variable_2="K_CMDN"/>
<map_variables variable_1="K_CMDN_Ca" variable_2="K_CMDN_Ca"/>
</connection>
<connection>
<map_components component_1="constants" component_2="CaB"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="Ca_leak"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="CMDN_buffer"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="TRPN_buffer"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="fast_Na"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="funny"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="K"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="K_ATP"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="K1"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="Kp"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="Kr"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="Ks"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="LCC"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="NaK"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="NaB"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="NCX"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="ns"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="pCa"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="RyR"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="SERCA"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="TCC"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="constants" component_2="TO"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
</model>
