- Author:
- Shelley Fong <sfon036@UoA.auckland.ac.nz>
- Date:
- 2022-05-24 13:25:22+12:00
- Desc:
- Adding composite cellml file which does not solve in Opencor
- Permanent Source URI:
- http://models.cellml.org/workspace/885/rawfile/0283a525ba827d63eedfe2603b3ac67034d711ef/FCU_cardiac_pH.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="FCU_cardiac_pH" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="units_and_constants/units_BG.cellml">
<units name="mM" units_ref="mM"/>
<units name="fmol" units_ref="fmol"/>
<units name="per_fmol" units_ref="per_fmol"/>
<units name="J_per_mol" units_ref="J_per_mol"/>
<units name="fmol_per_sec" units_ref="fmol_per_sec"/>
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="J_per_C" units_ref="J_per_C"/>
<units name="microm3" units_ref="microm3"/>
<units name="fF" units_ref="fF"/>
<units name="fC" units_ref="fC"/>
<units name="fA" units_ref="fA"/>
<units name="per_second" units_ref="per_second"/>
<units name="millivolt" units_ref="millivolt"/>
<units name="per_sec" units_ref="per_sec"/>
<units name="J_per_K_per_mol" units_ref="J_per_K_per_mol"/>
<units name="fmol_per_L" units_ref="fmol_per_L"/>
<units name="fmol_per_L_per_sec" units_ref="fmol_per_L_per_sec"/>
<units name="per_sec_per_fmol_per_L" units_ref="per_sec_per_fmol_per_L"/>
<units name="uM" units_ref="uM"/>
<units name="mM_per_sec" units_ref="mM_per_sec"/>
<units name="uM_per_sec" units_ref="uM_per_sec"/>
<units name="pL" units_ref="pL"/>
<units name="m_to_u" units_ref="m_to_u"/>
</import>
<import xlink:href="units_and_constants/constants_BG.cellml">
<component component_ref="constants" name="constants"/>
</import>
<import xlink:href="AE/BG_AE.cellml">
<component component_ref="AE" name="AE"/>
</import>
<import xlink:href="CHE/BG_CHE.cellml">
<component component_ref="CHE" name="CHE"/>
</import>
<import xlink:href="CO2_hyd/BG_CO2_hyd.cellml">
<component component_ref="CO2_hyd" name="CO2_hyd"/>
</import>
<import xlink:href="NBC/BG_NBC.cellml">
<component component_ref="NBC" name="NBC"/>
</import>
<import xlink:href="NHE/BG_NHE.cellml">
<component component_ref="NHE" name="NHE"/>
</import>
<import xlink:href="pH_B1/BG_pH_B1.cellml">
<component component_ref="pH_B1" name="pH_B1"/>
</import>
<import xlink:href="pH_B2/BG_pH_B2.cellml">
<component component_ref="pH_B2" name="pH_B2"/>
</import>
<component name="BG_parameters">
<variable initial_value="0.00234867" name="kappa_R61_AE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="7513.02" name="kappa_R12_AE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="516778" name="kappa_R23_AE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0185914" name="kappa_R34_AE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="508165" name="kappa_R45_AE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="7.3878e+09" name="kappa_R56_AE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="9.78487" name="kappa_R61_CHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0348831" name="kappa_R12_CHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="39258" name="kappa_R23_CHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.000148526" name="kappa_R34_CHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.28502e+06" name="kappa_R45_CHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="2.03037e+06" name="kappa_R56_CHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0335708" name="kappa_Re_CO2hyd" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.940306" name="kappa_R61_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="8.03772e+07" name="kappa_R12_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="3.18851e+06" name="kappa_R23_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="33.9127" name="kappa_R34_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0558481" name="kappa_R45_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="12.1431" name="kappa_R56_NBC" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="11.1987" name="kappa_R61_NHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.56101" name="kappa_R12_NHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="17590" name="kappa_R23_NHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.000383734" name="kappa_R34_NHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="4793.1" name="kappa_R45_NHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="152870" name="kappa_R56_NHE" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="15.649" name="kappa_Re_B1" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="4.79904" name="kappa_Re_B2" public_interface="out" units="fmol_per_sec"/>
<variable initial_value="0.0120343" name="K_HCO3_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0102316" name="K_HCO3_o" public_interface="out" units="per_fmol"/>
<variable initial_value="174.957" name="K_Cl_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000148749" name="K_Cl_o" public_interface="out" units="per_fmol"/>
<variable initial_value="39823" name="K_S1_AE" public_interface="out" units="per_fmol"/>
<variable initial_value="6931" name="K_S2_AE" public_interface="out" units="per_fmol"/>
<variable initial_value="5132.36" name="K_S3_AE" public_interface="out" units="per_fmol"/>
<variable initial_value="5219.35" name="K_S4_AE" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000817178" name="K_S5_AE" public_interface="out" units="per_fmol"/>
<variable initial_value="40396.9" name="K_S6_AE" public_interface="out" units="per_fmol"/>
<variable initial_value="196.899" name="K_OH_i" public_interface="out" units="per_fmol"/>
<variable initial_value="167.405" name="K_OH_o" public_interface="out" units="per_fmol"/>
<variable initial_value="6.8867" name="K_S1_CHE" public_interface="out" units="per_fmol"/>
<variable initial_value="91237.1" name="K_S2_CHE" public_interface="out" units="per_fmol"/>
<variable initial_value="123586" name="K_S3_CHE" public_interface="out" units="per_fmol"/>
<variable initial_value="2123.29" name="K_S4_CHE" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000181732" name="K_S5_CHE" public_interface="out" units="per_fmol"/>
<variable initial_value="0.118176" name="K_S6_CHE" public_interface="out" units="per_fmol"/>
<variable initial_value="3.85394e+06" name="K_CO2_i" public_interface="out" units="per_fmol"/>
<variable initial_value="65.6391" name="K_H_i" public_interface="out" units="per_fmol"/>
<variable initial_value="2093.48" name="K_Na_i" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000412929" name="K_Na_o" public_interface="out" units="per_fmol"/>
<variable initial_value="16.0526" name="K_S1_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="16.3314" name="K_S2_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="0.000677973" name="K_S3_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="38707.3" name="K_S4_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="1.081e+08" name="K_S5_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="2.85793" name="K_S6_NBC" public_interface="out" units="per_fmol"/>
<variable initial_value="12.947" name="K_H_o" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0791872" name="K_S1_NHE" public_interface="out" units="per_fmol"/>
<variable initial_value="73352.1" name="K_S2_NHE" public_interface="out" units="per_fmol"/>
<variable initial_value="514.873" name="K_S3_NHE" public_interface="out" units="per_fmol"/>
<variable initial_value="1889.51" name="K_S4_NHE" public_interface="out" units="per_fmol"/>
<variable initial_value="0.00724047" name="K_S5_NHE" public_interface="out" units="per_fmol"/>
<variable initial_value="0.291236" name="K_S6_NHE" public_interface="out" units="per_fmol"/>
<variable initial_value="70.7297" name="K_B1" public_interface="out" units="per_fmol"/>
<variable initial_value="0.0160745" name="K_HB1" public_interface="out" units="per_fmol"/>
<variable initial_value="230.64" name="K_B2" public_interface="out" units="per_fmol"/>
<variable initial_value="0.00151172" name="K_HB2" public_interface="out" units="per_fmol"/>
</component>
<component name="environment">
<variable name="time" public_interface="out" units="second"/>
<variable initial_value="509.2" name="q_HCO3_i" public_interface="out" units="fmol"/>
<variable initial_value="122.2952" name="q_HCO3_o" public_interface="out" units="fmol"/>
<variable initial_value="824.6" name="q_Cl_i" public_interface="out" units="fmol"/>
<variable initial_value="725.48" name="q_Cl_o" public_interface="out" units="fmol"/>
<variable initial_value="5.36764E-06" name="q_OH_i" public_interface="out" units="fmol"/>
<variable initial_value="1.30166E-06" name="q_OH_o" public_interface="out" units="fmol"/>
<variable initial_value="481.46" name="q_Na_i" public_interface="out" units="fmol"/>
<variable initial_value="725.48" name="q_Na_o" public_interface="out" units="fmol"/>
<variable initial_value="2.69019E-06" name="q_H_i" public_interface="out" units="fmol"/>
<variable initial_value="2.06299E-07" name="q_H_o" public_interface="out" units="fmol"/>
<variable initial_value="3199.6" name="q_B1" public_interface="out" units="fmol"/>
<variable initial_value="1e-12" name="q_HB1" public_interface="out" units="fmol"/>
<variable initial_value="1117.2" name="q_B2" public_interface="out" units="fmol"/>
<variable initial_value="1e-12" name="q_HB2" public_interface="out" units="fmol"/>
<variable initial_value="46.968" name="q_CO2_i" public_interface="out" units="fmol"/>
<!-- AE imports-->
<variable name="v_R61_AE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R12_AE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R23_AE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R34_AE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R45_AE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R56_AE" public_interface="in" units="fmol_per_sec"/>
<!-- CHE imports-->
<variable name="v_R61_CHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R12_CHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R23_CHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R34_CHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R45_CHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R56_CHE" public_interface="in" units="fmol_per_sec"/>
<!-- CO2_hyd imports-->
<variable name="v_Re_CO2hyd" public_interface="in" units="fmol_per_sec"/>
<!-- NBC imports-->
<variable name="v_R61_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R12_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R23_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R34_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R45_NBC" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R56_NBC" public_interface="in" units="fmol_per_sec"/>
<!-- NHE imports-->
<variable name="v_R61_NHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R12_NHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R23_NHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R34_NHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R45_NHE" public_interface="in" units="fmol_per_sec"/>
<variable name="v_R56_NHE" public_interface="in" units="fmol_per_sec"/>
<!-- pH_B1 imports-->
<variable name="v_Re_B1" public_interface="in" units="fmol_per_sec"/>
<!-- pH_B2 imports-->
<variable name="v_Re_B2" public_interface="in" units="fmol_per_sec"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_HCO3_i</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<ci>v_R56_AE</ci>
</apply>
<ci>v_R45_NBC</ci>
<ci>v_Re_CO2hyd</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_HCO3_o</ci>
</apply>
<apply>
<minus/>
<ci>v_R12_AE</ci>
<ci>v_R23_NBC</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_Cl_i</ci>
</apply>
<apply>
<plus/>
<ci>v_R45_AE</ci>
<ci>v_R45_CHE</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_Cl_o</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<ci>v_R23_AE</ci>
</apply>
<ci>v_R23_CHE</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_Na_i</ci>
</apply>
<apply>
<plus/>
<ci>v_R56_NBC</ci>
<ci>v_R45_NHE</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_Na_o</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<ci>v_R12_NBC</ci>
</apply>
<ci>v_R23_NHE</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_OH_i</ci>
</apply>
<apply>
<minus/>
<ci>v_R56_CHE</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_OH_o</ci>
</apply>
<ci>v_R12_CHE</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_H_i</ci>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<ci>v_R56_NHE</ci>
</apply>
<ci>v_Re_B1</ci>
</apply>
<ci>v_Re_B2</ci>
</apply>
<ci>v_Re_CO2hyd</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_H_o</ci>
</apply>
<ci>v_R12_NHE</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_B1</ci>
</apply>
<apply>
<minus/>
<ci>v_Re_B1</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_HB1</ci>
</apply>
<ci>v_Re_B1</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_B2</ci>
</apply>
<apply>
<minus/>
<ci>v_Re_B2</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_HB2</ci>
</apply>
<ci>v_Re_B2</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>q_CO2_i</ci>
</apply>
<apply>
<minus/>
<ci>v_Re_CO2hyd</ci>
</apply>
</apply>
</math>
<variable name="pH_i" units="dimensionless"/>
<variable name="pH_o" units="dimensionless"/>
<variable name="cH_i" units="mM"/>
<variable name="cH_o" units="mM"/>
<variable initial_value="38" name="w_i" units="pL"/>
<variable initial_value="5.182" name="w_o" units="pL"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>cH_i</ci>
<apply>
<divide/>
<ci>q_H_i</ci>
<ci>w_i</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>cH_o</ci>
<apply>
<divide/>
<ci>q_H_o</ci>
<ci>w_o</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>pH_i</ci>
<apply>
<minus/>
<apply>
<log/>
<ci>cH_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>pH_o</ci>
<apply>
<minus/>
<apply>
<log/>
<ci>cH_o</ci>
</apply>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="environment" component_2="AE"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_HCO3_i" variable_2="q_HCO3_i"/>
<map_variables variable_1="q_HCO3_o" variable_2="q_HCO3_o"/>
<map_variables variable_1="q_Cl_i" variable_2="q_Cl_i"/>
<map_variables variable_1="q_Cl_o" variable_2="q_Cl_o"/>
<map_variables variable_1="v_R61_AE" variable_2="v_R61_AE"/>
<map_variables variable_1="v_R12_AE" variable_2="v_R12_AE"/>
<map_variables variable_1="v_R23_AE" variable_2="v_R23_AE"/>
<map_variables variable_1="v_R34_AE" variable_2="v_R34_AE"/>
<map_variables variable_1="v_R45_AE" variable_2="v_R45_AE"/>
<map_variables variable_1="v_R56_AE" variable_2="v_R56_AE"/>
</connection>
<connection>
<map_components component_1="environment" component_2="CHE"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_OH_i" variable_2="q_OH_i"/>
<map_variables variable_1="q_OH_o" variable_2="q_OH_o"/>
<map_variables variable_1="q_Cl_i" variable_2="q_Cl_i"/>
<map_variables variable_1="q_Cl_o" variable_2="q_Cl_o"/>
<map_variables variable_1="v_R61_CHE" variable_2="v_R61_CHE"/>
<map_variables variable_1="v_R12_CHE" variable_2="v_R12_CHE"/>
<map_variables variable_1="v_R23_CHE" variable_2="v_R23_CHE"/>
<map_variables variable_1="v_R34_CHE" variable_2="v_R34_CHE"/>
<map_variables variable_1="v_R45_CHE" variable_2="v_R45_CHE"/>
<map_variables variable_1="v_R56_CHE" variable_2="v_R56_CHE"/>
</connection>
<connection>
<map_components component_1="environment" component_2="CO2_hyd"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_CO2_i" variable_2="q_CO2_i"/>
<map_variables variable_1="q_HCO3_i" variable_2="q_HCO3_i"/>
<map_variables variable_1="q_H_i" variable_2="q_H_i"/>
<map_variables variable_1="v_Re_CO2hyd" variable_2="v_Re_CO2hyd"/>
</connection>
<connection>
<map_components component_1="environment" component_2="NBC"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="q_HCO3_i" variable_2="q_HCO3_i"/>
<map_variables variable_1="q_HCO3_o" variable_2="q_HCO3_o"/>
<map_variables variable_1="v_R61_NBC" variable_2="v_R61_NBC"/>
<map_variables variable_1="v_R12_NBC" variable_2="v_R12_NBC"/>
<map_variables variable_1="v_R23_NBC" variable_2="v_R23_NBC"/>
<map_variables variable_1="v_R34_NBC" variable_2="v_R34_NBC"/>
<map_variables variable_1="v_R45_NBC" variable_2="v_R45_NBC"/>
<map_variables variable_1="v_R56_NBC" variable_2="v_R56_NBC"/>
</connection>
<connection>
<map_components component_1="environment" component_2="NHE"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_H_i" variable_2="q_H_i"/>
<map_variables variable_1="q_H_o" variable_2="q_H_o"/>
<map_variables variable_1="q_Na_i" variable_2="q_Na_i"/>
<map_variables variable_1="q_Na_o" variable_2="q_Na_o"/>
<map_variables variable_1="v_R61_NHE" variable_2="v_R61_NHE"/>
<map_variables variable_1="v_R12_NHE" variable_2="v_R12_NHE"/>
<map_variables variable_1="v_R23_NHE" variable_2="v_R23_NHE"/>
<map_variables variable_1="v_R34_NHE" variable_2="v_R34_NHE"/>
<map_variables variable_1="v_R45_NHE" variable_2="v_R45_NHE"/>
<map_variables variable_1="v_R56_NHE" variable_2="v_R56_NHE"/>
</connection>
<connection>
<map_components component_1="environment" component_2="pH_B1"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_H_i" variable_2="q_H_i"/>
<map_variables variable_1="q_B1" variable_2="q_B1"/>
<map_variables variable_1="q_HB1" variable_2="q_HB1"/>
<map_variables variable_1="v_Re_B1" variable_2="v_Re_B1"/>
</connection>
<connection>
<map_components component_1="environment" component_2="pH_B2"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="q_H_i" variable_2="q_H_i"/>
<map_variables variable_1="q_B2" variable_2="q_B2"/>
<map_variables variable_1="q_HB2" variable_2="q_HB2"/>
<map_variables variable_1="v_Re_B2" variable_2="v_Re_B2"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="AE"/>
<map_variables variable_1="kappa_R61_AE" variable_2="kappa_R61_AE"/>
<map_variables variable_1="kappa_R12_AE" variable_2="kappa_R12_AE"/>
<map_variables variable_1="kappa_R23_AE" variable_2="kappa_R23_AE"/>
<map_variables variable_1="kappa_R34_AE" variable_2="kappa_R34_AE"/>
<map_variables variable_1="kappa_R45_AE" variable_2="kappa_R45_AE"/>
<map_variables variable_1="kappa_R56_AE" variable_2="kappa_R56_AE"/>
<map_variables variable_1="K_HCO3_i" variable_2="K_HCO3_i"/>
<map_variables variable_1="K_HCO3_o" variable_2="K_HCO3_o"/>
<map_variables variable_1="K_Cl_i" variable_2="K_Cl_i"/>
<map_variables variable_1="K_Cl_o" variable_2="K_Cl_o"/>
<map_variables variable_1="K_S1_AE" variable_2="K_S1_AE"/>
<map_variables variable_1="K_S2_AE" variable_2="K_S2_AE"/>
<map_variables variable_1="K_S3_AE" variable_2="K_S3_AE"/>
<map_variables variable_1="K_S4_AE" variable_2="K_S4_AE"/>
<map_variables variable_1="K_S5_AE" variable_2="K_S5_AE"/>
<map_variables variable_1="K_S6_AE" variable_2="K_S6_AE"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="CHE"/>
<map_variables variable_1="kappa_R61_CHE" variable_2="kappa_R61_CHE"/>
<map_variables variable_1="kappa_R12_CHE" variable_2="kappa_R12_CHE"/>
<map_variables variable_1="kappa_R23_CHE" variable_2="kappa_R23_CHE"/>
<map_variables variable_1="kappa_R34_CHE" variable_2="kappa_R34_CHE"/>
<map_variables variable_1="kappa_R45_CHE" variable_2="kappa_R45_CHE"/>
<map_variables variable_1="kappa_R56_CHE" variable_2="kappa_R56_CHE"/>
<map_variables variable_1="K_OH_i" variable_2="K_OH_i"/>
<map_variables variable_1="K_OH_o" variable_2="K_OH_o"/>
<map_variables variable_1="K_Cl_i" variable_2="K_Cl_i"/>
<map_variables variable_1="K_Cl_o" variable_2="K_Cl_o"/>
<map_variables variable_1="K_S1_CHE" variable_2="K_S1_CHE"/>
<map_variables variable_1="K_S2_CHE" variable_2="K_S2_CHE"/>
<map_variables variable_1="K_S3_CHE" variable_2="K_S3_CHE"/>
<map_variables variable_1="K_S4_CHE" variable_2="K_S4_CHE"/>
<map_variables variable_1="K_S5_CHE" variable_2="K_S5_CHE"/>
<map_variables variable_1="K_S6_CHE" variable_2="K_S6_CHE"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="CO2_hyd"/>
<map_variables variable_1="kappa_Re_CO2hyd" variable_2="kappa_Re_CO2hyd"/>
<map_variables variable_1="K_CO2_i" variable_2="K_CO2_i"/>
<map_variables variable_1="K_HCO3_i" variable_2="K_HCO3_i"/>
<map_variables variable_1="K_H_i" variable_2="K_H_i"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="NBC"/>
<map_variables variable_1="kappa_R61_NBC" variable_2="kappa_R61_NBC"/>
<map_variables variable_1="kappa_R12_NBC" variable_2="kappa_R12_NBC"/>
<map_variables variable_1="kappa_R23_NBC" variable_2="kappa_R23_NBC"/>
<map_variables variable_1="kappa_R34_NBC" variable_2="kappa_R34_NBC"/>
<map_variables variable_1="kappa_R45_NBC" variable_2="kappa_R45_NBC"/>
<map_variables variable_1="kappa_R56_NBC" variable_2="kappa_R56_NBC"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_HCO3_i" variable_2="K_HCO3_i"/>
<map_variables variable_1="K_HCO3_o" variable_2="K_HCO3_o"/>
<map_variables variable_1="K_S1_NBC" variable_2="K_S1_NBC"/>
<map_variables variable_1="K_S2_NBC" variable_2="K_S2_NBC"/>
<map_variables variable_1="K_S3_NBC" variable_2="K_S3_NBC"/>
<map_variables variable_1="K_S4_NBC" variable_2="K_S4_NBC"/>
<map_variables variable_1="K_S5_NBC" variable_2="K_S5_NBC"/>
<map_variables variable_1="K_S6_NBC" variable_2="K_S6_NBC"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="NHE"/>
<map_variables variable_1="kappa_R61_NHE" variable_2="kappa_R61_NHE"/>
<map_variables variable_1="kappa_R12_NHE" variable_2="kappa_R12_NHE"/>
<map_variables variable_1="kappa_R23_NHE" variable_2="kappa_R23_NHE"/>
<map_variables variable_1="kappa_R34_NHE" variable_2="kappa_R34_NHE"/>
<map_variables variable_1="kappa_R45_NHE" variable_2="kappa_R45_NHE"/>
<map_variables variable_1="kappa_R56_NHE" variable_2="kappa_R56_NHE"/>
<map_variables variable_1="K_H_i" variable_2="K_H_i"/>
<map_variables variable_1="K_H_o" variable_2="K_H_o"/>
<map_variables variable_1="K_Na_i" variable_2="K_Na_i"/>
<map_variables variable_1="K_Na_o" variable_2="K_Na_o"/>
<map_variables variable_1="K_S1_NHE" variable_2="K_S1_NHE"/>
<map_variables variable_1="K_S2_NHE" variable_2="K_S2_NHE"/>
<map_variables variable_1="K_S3_NHE" variable_2="K_S3_NHE"/>
<map_variables variable_1="K_S4_NHE" variable_2="K_S4_NHE"/>
<map_variables variable_1="K_S5_NHE" variable_2="K_S5_NHE"/>
<map_variables variable_1="K_S6_NHE" variable_2="K_S6_NHE"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="pH_B1"/>
<map_variables variable_1="kappa_Re_B1" variable_2="kappa_Re_B1"/>
<map_variables variable_1="K_H_i" variable_2="K_H_i"/>
<map_variables variable_1="K_B1" variable_2="K_B1"/>
<map_variables variable_1="K_HB1" variable_2="K_HB1"/>
</connection>
<connection>
<map_components component_1="BG_parameters" component_2="pH_B2"/>
<map_variables variable_1="kappa_Re_B2" variable_2="kappa_Re_B2"/>
<map_variables variable_1="K_H_i" variable_2="K_H_i"/>
<map_variables variable_1="K_B2" variable_2="K_B2"/>
<map_variables variable_1="K_HB2" variable_2="K_HB2"/>
</connection>
<connection>
<map_components component_1="constants" component_2="AE"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="CHE"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="CO2_hyd"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="NBC"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="NHE"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="pH_B1"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
<connection>
<map_components component_1="constants" component_2="pH_B2"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
</connection>
</model>
