- Author:
- rcai987 <devnull@localhost>
- Date:
- 2015-01-16 12:39:31+13:00
- Desc:
- Added annotations to chay_1997 model
- Permanent Source URI:
- http://models.cellml.org/workspace/chay_1997/rawfile/d802e054fe420d488fa7bc73f32c103269d20fff/chay_1997.cellml
<?xml version="1.0"?>
<model xmlns="http://www.cellml.org/cellml/1.0#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:cellml="http://www.cellml.org/cellml/1.0#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xml:base="file:///H:/chay_1997/chay_1997.cellml" cmeta:id="chay_1997" name="chay_1997">
<documentation xmlns="http://cellml.org/tmp-documentation">
<article>
<articleinfo>
<title>Extracellular And Intracellular Calcium Effects On Pancreatic Beta-Cells</title>
<author>
<firstname>Catherine</firstname>
<surname>Lloyd</surname>
<affiliation>
<shortaffil>Auckland Bioengineering Institute, The university of Auckland</shortaffil>
</affiliation>
</author>
</articleinfo>
<section id="sec_status">
<title>Model Status</title>
<para>
This CellML model runs in both OpenCell and COR to reproduce the published results. The value for the variable 'Ca_o' in the component 'calcium_current' can be altered to 0, 2.5, 5 or 7.5 mM to reproduce figures 5 a,b,c,d, respectively.
</para>
</section>
<sect1 id="sec_structure">
<title>Model Structure</title>
<para>
ABSTRACT: The extracellular calcium concentration has interesting effects on bursting of pancreatic beta-cells. The mechanism underlying the extracellular Ca2+ effect is not well understood. By incorporating a low-threshold transient inward current to the store-operated bursting model of Chay, this paper elucidates the role of the extracellular Ca2+ concentration in influencing electrical activity, intracellular Ca2+ concentration, and the luminal Ca2+ concentration in the intracellular Ca2+ store. The possibility that this inward current is a carbachol-sensitive and TTX-insensitive Na+ current discovered by others is discussed. In addition, this paper explains how these three variables respond when various pharmacological agents are applied to the store-operated model.
</para>
<para>
The original paper reference is cited below:
</para>
<para>
Effects of extracellular Calcium on Electrical Bursting and Intracellular and Luminal Calcium Oscillations in Insulin Secreting Pancreatic Beta-Cells, Teresa Ree Chay, 1997,
<emphasis>Biophysical Journal</emphasis>
, 73, 1673-1688. <ulink url="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9284334&dopt=Abstract">PubMed ID: 9284334</ulink>
</para>
<informalfigure float="0" id="fig_cell_diagram">
<mediaobject>
<imageobject>
<objectinfo>
<title>diagram of the mitochondrial Ca2+ handling model</title>
</objectinfo>
<imagedata fileref="chay_1997.png"/>
</imageobject>
</mediaobject>
<caption>A schematic representation of the current and fluxes captured by the Chay 1997 pancreatic beta-cell model. This diagram shows the plasma membrane currents associated with burst and spike oscillations: the fast current, I<subscript>fast</subscript>; the calcium current, I <subscript>Ca<superscript>2+</superscript>
</subscript>; the cationic nonselective inward current, I<subscript>NS</subscript>; the delayed-rectifying K<superscript>+</superscript> current, I<subscript>K(dr)</subscript>, the calcium-sensitive K<superscript>+</superscript> current, I<subscript>K(Ca)</subscript>; the ATP-sensitive K<superscript>+</superscript> current, I<subscript>K(ATP)</subscript>; and the Na<superscript>+</superscript> leak current, I<subscript>Na(L)</subscript>. The ER intracellular Ca<superscript>2+</superscript> store is also shown with its associated transmembrane calcium fluxes: calcium release, J<subscript>rel</subscript>; and calcium uptake by the Ca<superscript>2+</superscript>-ATPase, J<subscript>pump</subscript>.</caption>
</informalfigure>
</sect1>
</article>
</documentation>
<units name="per_second">
<unit exponent="-1" units="second"/>
</units>
<units name="millivolt">
<unit prefix="milli" units="volt"/>
</units>
<units name="per_millivolt">
<unit exponent="-1" units="millivolt"/>
</units>
<units name="micromolar">
<unit prefix="micro" units="mole"/>
<unit exponent="-1" units="litre"/>
</units>
<units name="microS_per_cm2">
<unit prefix="micro" units="siemens"/>
<unit exponent="-2" prefix="centi" units="metre"/>
</units>
<units name="microF_per_cm2">
<unit prefix="micro" units="farad"/>
<unit exponent="-2" prefix="centi" units="metre"/>
</units>
<units name="nanoA_per_cm2">
<unit prefix="nano" units="ampere"/>
<unit exponent="-2" prefix="centi" units="metre"/>
</units>
<units name="nanoA_per_micromolar_per_cm2">
<unit prefix="nano" units="ampere"/>
<unit exponent="-1" units="micromolar"/>
<unit exponent="-2" prefix="centi" units="metre"/>
</units>
<units name="micromolar_cm2_per_nanoA_per_second">
<unit exponent="-1" prefix="nano" units="ampere"/>
<unit units="micromolar"/>
<unit exponent="2" prefix="centi" units="metre"/>
<unit exponent="-1" units="second"/>
</units>
<units name="millijoule_per_mole_kelvin">
<unit prefix="milli" units="joule"/>
<unit exponent="-1" units="mole"/>
<unit exponent="-1" units="kelvin"/>
</units>
<units name="coulomb_per_mole">
<unit units="coulomb"/>
<unit exponent="-1" units="mole"/>
</units>
<component name="environment">
<variable cmeta:id="environment_time" name="time" public_interface="out" units="second"/>
</component>
<component cmeta:id="id_00053" name="membrane">
<variable cmeta:id="membrane_V" initial_value="-38.34146" name="V" public_interface="out" units="millivolt"/>
<variable initial_value="8314" name="R" public_interface="out" units="millijoule_per_mole_kelvin"/>
<variable initial_value="310" name="T" public_interface="out" units="kelvin"/>
<variable initial_value="96485" name="F" public_interface="out" units="coulomb_per_mole"/>
<variable initial_value="1" name="Cm" units="microF_per_cm2"/>
<variable name="time" public_interface="in" units="second"/>
<variable cmeta:id="id_00047" name="i_K_dr" public_interface="in" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00048" name="i_K_Ca" public_interface="in" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00049" name="i_K_ATP" public_interface="in" units="nanoA_per_cm2"/>
<variable name="i_fast" public_interface="in" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00050" name="i_Ca" public_interface="in" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00052" name="i_NS" public_interface="in" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00051" name="i_NaL" public_interface="in" units="nanoA_per_cm2"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>i_K_dr</ci>
<ci>i_K_Ca</ci>
<ci>i_K_ATP</ci>
<ci>i_fast</ci>
<ci>i_Ca</ci>
<ci>i_NS</ci>
<ci>i_NaL</ci>
</apply>
</apply>
<ci>Cm</ci>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00056" name="fast_current">
<variable cmeta:id="fast_current_i_fast" name="i_fast" public_interface="out" units="nanoA_per_cm2"/>
<variable initial_value="600" name="g_fast" units="microS_per_cm2"/>
<variable initial_value="80" name="V_fast" units="millivolt"/>
<variable name="time" private_interface="out" public_interface="in" units="second"/>
<variable name="V" private_interface="out" public_interface="in" units="millivolt"/>
<variable name="m_infinity" private_interface="in" units="dimensionless"/>
<variable name="h" private_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_fast</ci>
<apply>
<times/>
<ci>g_fast</ci>
<apply>
<power/>
<ci>m_infinity</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
<ci>h</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>V_fast</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00054" name="fast_current_m_gate">
<variable name="m_infinity" public_interface="out" units="dimensionless"/>
<variable initial_value="-25" name="Vm" units="millivolt"/>
<variable initial_value="9" name="Sm" units="millivolt"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>m_infinity</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vm</ci>
<ci>V</ci>
</apply>
<ci>Sm</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00055" name="fast_current_h_gate">
<variable initial_value="0.214723" name="h" public_interface="out" units="dimensionless"/>
<variable initial_value="12.5" name="lamda_h" units="per_second"/>
<variable name="tau_h" units="second"/>
<variable name="h_infinity" units="dimensionless"/>
<variable initial_value="-48" name="Vh" units="millivolt"/>
<variable initial_value="-7" name="Sh" units="millivolt"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>h</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>h_infinity</ci>
<ci>h</ci>
</apply>
<ci>tau_h</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>h_infinity</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vh</ci>
<ci>V</ci>
</apply>
<ci>Sh</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_h</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<times/>
<ci>lamda_h</ci>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vh</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>Sh</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<ci>Vh</ci>
</apply>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>Sh</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00001" name="calcium_current">
<variable cmeta:id="calcium_current_i_Ca" name="i_Ca" public_interface="out" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00002" initial_value="1" name="K_Ca" private_interface="out" public_interface="out" units="micromolar"/>
<variable cmeta:id="id_00003" initial_value="2" name="P_Ca" units="nanoA_per_micromolar_per_cm2"/>
<variable cmeta:id="id_00005" initial_value="2500" name="Ca_o" units="micromolar"/>
<variable name="R" public_interface="in" units="millijoule_per_mole_kelvin"/>
<variable name="F" public_interface="in" units="coulomb_per_mole"/>
<variable name="T" public_interface="in" units="kelvin"/>
<variable name="time" private_interface="out" public_interface="in" units="second"/>
<variable name="V" private_interface="out" public_interface="in" units="millivolt"/>
<variable cmeta:id="id_00004" name="Ca_i" private_interface="out" public_interface="in" units="micromolar"/>
<variable name="f_infinity" private_interface="in" units="dimensionless"/>
<variable name="d" private_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Ca</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>P_Ca</ci>
<ci>d</ci>
<ci>f_infinity</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
<apply>
<minus/>
<ci>Ca_o</ci>
<apply>
<times/>
<ci>Ca_i</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00006" name="calcium_current_d_gate">
<variable cmeta:id="id_00016" initial_value="0.0031711238" name="d" public_interface="out" units="dimensionless"/>
<variable cmeta:id="id_00015" initial_value="2.5" name="lamda_d" units="per_second"/>
<variable cmeta:id="id_00014" name="tau_d" units="second"/>
<variable cmeta:id="id_00013" name="d_infinity" units="dimensionless"/>
<variable cmeta:id="id_00012" initial_value="-10" name="Vd" units="millivolt"/>
<variable cmeta:id="id_00011" initial_value="5" name="Sd" units="millivolt"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_infinity</ci>
<ci>d</ci>
</apply>
<ci>tau_d</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>d_infinity</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vd</ci>
<ci>V</ci>
</apply>
<ci>Sd</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<times/>
<ci>lamda_d</ci>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vd</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>Sd</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<ci>Vd</ci>
</apply>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>Sd</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00007" name="calcium_current_f_gate">
<variable cmeta:id="id_00009" name="f_infinity" public_interface="out" units="dimensionless"/>
<variable cmeta:id="id_00008" name="K_Ca" public_interface="in" units="micromolar"/>
<variable cmeta:id="id_00010" name="Ca_i" public_interface="in" units="micromolar"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>f_infinity</ci>
<apply>
<divide/>
<ci>K_Ca</ci>
<apply>
<plus/>
<ci>K_Ca</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00017" name="cationic_nonselective_inward_current">
<variable cmeta:id="cationic_nonselective_inward_current_i_NS" name="i_NS" public_interface="out" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00018" initial_value="5" name="g_NS" units="microS_per_cm2"/>
<variable cmeta:id="id_00019" initial_value="50" name="K_NS" units="micromolar"/>
<variable cmeta:id="id_00020" initial_value="-20" name="VNS" units="millivolt"/>
<variable name="Ca_lum" public_interface="in" units="micromolar"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_NS</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>g_NS</ci>
<apply>
<power/>
<ci>K_NS</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>K_NS</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<ci>Ca_lum</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<ci>VNS</ci>
</apply>
<apply>
<minus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="per_millivolt">0.1</cn>
<apply>
<minus/>
<ci>VNS</ci>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="millivolt">10</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00021" name="delayed_rectifier_K_channel_current">
<variable cmeta:id="delayed_rectifier_K_channel_current_i_K_dr" name="i_K_dr" public_interface="out" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00022" initial_value="-75" name="V_K" public_interface="out" units="millivolt"/>
<variable cmeta:id="id_00023" initial_value="600" name="g_K_dr" units="microS_per_cm2"/>
<variable name="time" private_interface="out" public_interface="in" units="second"/>
<variable name="V" private_interface="out" public_interface="in" units="millivolt"/>
<variable name="n" private_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_K_dr</ci>
<apply>
<times/>
<ci>g_K_dr</ci>
<apply>
<power/>
<ci>n</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">4</cn>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>V_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00024" name="delayed_rectifier_K_channel_current_n_gate">
<variable cmeta:id="id_00025" initial_value="0.1836403" name="n" public_interface="out" units="dimensionless"/>
<variable cmeta:id="id_00026" initial_value="12.5" name="lamda_n" units="per_second"/>
<variable cmeta:id="id_00027" initial_value="-18" name="Vn" units="millivolt"/>
<variable cmeta:id="id_00028" initial_value="14" name="Sn" units="millivolt"/>
<variable cmeta:id="id_00029" name="n_infinity" units="dimensionless"/>
<variable cmeta:id="id_00030" name="tau_n" units="second"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>n</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>n_infinity</ci>
<ci>n</ci>
</apply>
<ci>tau_n</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>n_infinity</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vn</ci>
<ci>V</ci>
</apply>
<ci>Sn</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_n</ci>
<apply>
<divide/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">1</cn>
<apply>
<times/>
<ci>lamda_n</ci>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vn</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>Sn</ci>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<ci>Vn</ci>
</apply>
<apply>
<times/>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">2</cn>
<ci>Sn</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00031" name="Ca_sensitive_K_current">
<variable cmeta:id="Ca_sensitive_K_current_i_K_Ca" name="i_K_Ca" public_interface="out" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00032" initial_value="5" name="g_K_Ca" units="microS_per_cm2"/>
<variable cmeta:id="id_00033" name="K_Ca" public_interface="in" units="micromolar"/>
<variable name="time" public_interface="in" units="second"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable cmeta:id="id_00035" name="V_K" public_interface="in" units="millivolt"/>
<variable cmeta:id="id_00034" name="Ca_i" public_interface="in" units="micromolar"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_K_Ca</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>g_K_Ca</ci>
<apply>
<power/>
<ci>Ca_i</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>K_Ca</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<ci>Ca_i</ci>
<cn xmlns:cellml="http://www.cellml.org/cellml/1.0#" cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>V_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00036" name="ATP_sensitive_K_current">
<variable cmeta:id="ATP_sensitive_K_current_i_K_ATP" name="i_K_ATP" public_interface="out" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00037" initial_value="2" name="g_K_ATP" units="microS_per_cm2"/>
<variable name="time" public_interface="in" units="second"/>
<variable name="V" public_interface="in" units="millivolt"/>
<variable name="V_K" public_interface="in" units="millivolt"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_K_ATP</ci>
<apply>
<times/>
<ci>g_K_ATP</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>V_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00038" name="Na_leak_current">
<variable cmeta:id="Na_leak_current_i_NaL" name="i_NaL" public_interface="out" units="nanoA_per_cm2"/>
<variable cmeta:id="id_00039" initial_value="0.3" name="g_NaL" units="microS_per_cm2"/>
<variable cmeta:id="id_00040" initial_value="80" name="V_Na" units="millivolt"/>
<variable name="time" public_interface="in" units="second"/>
<variable name="V" public_interface="in" units="millivolt"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_NaL</ci>
<apply>
<times/>
<ci>g_NaL</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>V_Na</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component cmeta:id="id_00041" name="cytosolic_calcium">
<variable cmeta:id="cytosolic_calcium_Ca_i" initial_value="0.6959466" name="Ca_i" public_interface="out" units="micromolar"/>
<variable cmeta:id="cytosolic_calcium_Ca_lum" initial_value="102.686" name="Ca_lum" public_interface="out" units="micromolar"/>
<variable cmeta:id="id_00042" initial_value="0.2" name="k_rel" units="per_second"/>
<variable cmeta:id="id_00043" initial_value="7" name="k_Ca" units="per_second"/>
<variable cmeta:id="id_00044" initial_value="30" name="k_pump" units="per_second"/>
<variable cmeta:id="id_00046" initial_value="0.2" name="omega" units="micromolar_cm2_per_nanoA_per_second"/>
<variable cmeta:id="id_00045" name="i_Ca" public_interface="in" units="nanoA_per_cm2"/>
<variable name="time" public_interface="in" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_i</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>k_rel</ci>
<apply>
<minus/>
<ci>Ca_lum</ci>
<ci>Ca_i</ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>omega</ci>
<ci>i_Ca</ci>
</apply>
<apply>
<times/>
<ci>k_Ca</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<times/>
<ci>k_pump</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_lum</ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<apply>
<minus/>
<ci>k_rel</ci>
</apply>
<apply>
<minus/>
<ci>Ca_lum</ci>
<ci>Ca_i</ci>
</apply>
</apply>
<apply>
<times/>
<ci>k_pump</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="fast_current">
<component_ref component="fast_current_m_gate"/>
<component_ref component="fast_current_h_gate"/>
</component_ref>
<component_ref component="calcium_current">
<component_ref component="calcium_current_d_gate"/>
<component_ref component="calcium_current_f_gate"/>
</component_ref>
<component_ref component="delayed_rectifier_K_channel_current">
<component_ref component="delayed_rectifier_K_channel_current_n_gate"/>
</component_ref>
</group>
<connection>
<map_components component_1="membrane" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="fast_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="calcium_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="cationic_nonselective_inward_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="delayed_rectifier_K_channel_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Ca_sensitive_K_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ATP_sensitive_K_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Na_leak_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="cytosolic_calcium" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="fast_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_fast" variable_2="i_fast"/>
</connection>
<connection>
<map_components component_1="calcium_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Ca" variable_2="i_Ca"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="cationic_nonselective_inward_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_NS" variable_2="i_NS"/>
</connection>
<connection>
<map_components component_1="delayed_rectifier_K_channel_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_K_dr" variable_2="i_K_dr"/>
</connection>
<connection>
<map_components component_1="Ca_sensitive_K_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_K_Ca" variable_2="i_K_Ca"/>
</connection>
<connection>
<map_components component_1="ATP_sensitive_K_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_K_ATP" variable_2="i_K_ATP"/>
</connection>
<connection>
<map_components component_1="Na_leak_current" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_NaL" variable_2="i_NaL"/>
</connection>
<connection>
<map_components component_1="calcium_current" component_2="cytosolic_calcium"/>
<map_variables variable_1="i_Ca" variable_2="i_Ca"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
</connection>
<connection>
<map_components component_1="Ca_sensitive_K_current" component_2="cytosolic_calcium"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
</connection>
<connection>
<map_components component_1="calcium_current" component_2="Ca_sensitive_K_current"/>
<map_variables variable_1="K_Ca" variable_2="K_Ca"/>
</connection>
<connection>
<map_components component_1="delayed_rectifier_K_channel_current" component_2="ATP_sensitive_K_current"/>
<map_variables variable_1="V_K" variable_2="V_K"/>
</connection>
<connection>
<map_components component_1="delayed_rectifier_K_channel_current" component_2="Ca_sensitive_K_current"/>
<map_variables variable_1="V_K" variable_2="V_K"/>
</connection>
<connection>
<map_components component_1="cationic_nonselective_inward_current" component_2="cytosolic_calcium"/>
<map_variables variable_1="Ca_lum" variable_2="Ca_lum"/>
</connection>
<connection>
<map_components component_1="fast_current" component_2="fast_current_m_gate"/>
<map_variables variable_1="m_infinity" variable_2="m_infinity"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="fast_current" component_2="fast_current_h_gate"/>
<map_variables variable_1="h" variable_2="h"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="calcium_current" component_2="calcium_current_f_gate"/>
<map_variables variable_1="f_infinity" variable_2="f_infinity"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="K_Ca" variable_2="K_Ca"/>
</connection>
<connection>
<map_components component_1="calcium_current" component_2="calcium_current_d_gate"/>
<map_variables variable_1="d" variable_2="d"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="delayed_rectifier_K_channel_current" component_2="delayed_rectifier_K_channel_current_n_gate"/>
<map_variables variable_1="n" variable_2="n"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<rdf:RDF><rdf:Description rdf:about="#id_00001"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#calcium_current_i_Ca"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00002"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00003"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00004"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00005"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00006"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00007"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00008"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00009"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00010"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00011"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00012"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00013"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00014"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00015"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00016"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00017"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015326"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#cationic_nonselective_inward_current_i_NS"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015326"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00018"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015326"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00019"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015326"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00020"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015326"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00021"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#delayed_rectifier_K_channel_current_i_K_dr"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00022"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00023"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00024"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00025"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00026"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00027"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00028"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00029"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00030"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00031"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015269"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#Ca_sensitive_K_current_i_K_Ca"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015269"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00032"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015269"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00033"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015269"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00034"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015269"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00035"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00036"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008282"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#ATP_sensitive_K_current_i_K_ATP"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008282"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00037"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008282"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00038"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0022840"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#Na_leak_current_i_NaL"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0022840"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00039"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0022840"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00040"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0022840"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00041"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#cytosolic_calcium_Ca_i"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#cytosolic_calcium_Ca_lum"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00042"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00043"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00044"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00045"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:39124"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00046"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0051480"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00047"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005251"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00048"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015269"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00049"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005267"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034705"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005249"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008076"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0008282"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00050"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005262"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034704"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005891"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005245"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00051"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005248"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0001518"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00052"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0015326"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00053"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0030322"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0060075"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0042391"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00054"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0001518"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:38634"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00055"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0001518"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/chebi/CHEBI:38634"/></isVersionOf></rdf:Description><rdf:Description rdf:about="#id_00056"><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005272"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0034706"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0005248"/></isVersionOf><isVersionOf xmlns="http://biomodels.net/biology-qualifiers/"><rdf:Description rdf:about="http://identifiers.org/go/GO:0001518"/></isVersionOf></rdf:Description></rdf:RDF></model>
