<?xml version="1.0" encoding="utf-8"?>
<model name="FINAL" cmeta:id="FINAL" xmlns="http://www.cellml.org/cellml/1.0#" xmlns:cellml="http://www.cellml.org/cellml/1.0#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#">
<documentation xmlns="http://cellml.org/tmp-documentation">
<article>
<section id="sec_status">
<title>Model Status</title>
<para>
This model was developed in CellML and runs in COR.
</para>
</section>
<sect1 id="sec_structure">
<title>Model Structure</title>
<para>
This model integrates a sinoatrial node model based on the work of Courtemanche et al. (1998), Chandler et al. (2009), and Verkerk et al. (2007). This is connected to a ventricular model, very similar to the approach of Shim et al. (2006). This, in turn, is connected to a lumped parameter, compartment model of the circulatory model. The cardiovascular model(s) are linked to a simple lung model from Athanasiades et al. (2000) via the gas exchange model of Liu et al. (1998).
</para>
</sect1>
</article>
</documentation>
<units name="millivolt">
<unit units="volt" prefix="milli"/>
</units>
<units name="mMsq">
<unit units="mM" exponent="2"/>
</units>
<units name="per_millivolt">
<unit units="millivolt" exponent="-1"/>
</units>
<units name="per_millivolt_millisecond">
<unit units="millivolt" exponent="-1"/>
<unit units="millisecond" exponent="-1"/>
</units>
<units name="millisecond_per_millimolar">
<unit units="millisecond"/>
<unit units="millimolar" exponent="-1"/>
</units>
<units name="picoA">
<unit units="ampere" prefix="pico"/>
</units>
<units name="picoA_per_picoF">
<unit units="ampere" prefix="pico"/>
<unit units="farad" prefix="pico" exponent="-1"/>
</units>
<units name="nanoS_per_picoF">
<unit units="siemens" prefix="nano"/>
<unit units="farad" prefix="pico" exponent="-1"/>
</units>
<units name="picoF">
<unit units="farad" prefix="pico"/>
</units>
<units name="micrometre_3">
<unit units="metre" prefix="micro" exponent="3"/>
</units>
<units name="per_micrometre_3">
<unit units="metre" prefix="micro" exponent="-3"/>
</units>
<units name="mm2">
<unit units="metre" prefix="milli" exponent="2"/>
</units>
<units name="joule_per_mole_kelvin">
<unit units="joule"/>
<unit units="mole" exponent="-1"/>
<unit units="kelvin" exponent="-1"/>
</units>
<units name="coulomb_per_millimole">
<unit units="coulomb"/>
<unit units="mole" prefix="milli" exponent="-1"/>
</units>
<units name="centisecond">
<unit units="second" prefix="centi"/>
</units>
<units name="per_millisecond">
<unit units="second" prefix="milli" exponent="-1"/>
</units>
<units name="millimolar">
<unit units="mole" prefix="milli"/>
<unit units="litre" exponent="-1"/>
</units>
<units name="millimolar2">
<unit units="millimolar" exponent="2"/>
</units>
<units name="millimolar_per_millisecond">
<unit units="millimolar"/>
<unit units="second" prefix="milli" exponent="-1"/>
</units>
<units name="mN_per_mm2_micrometre_millimolar">
<unit units="newton" prefix="milli"/>
<unit units="metre" prefix="milli" exponent="-2"/>
<unit units="micrometre" exponent="-1"/>
<unit units="millimolar" exponent="-1"/>
</units>
<units name="millisecond_per_micrometre2">
<unit units="millisecond"/>
<unit units="micrometre" exponent="-2"/>
</units>
<units name="per_millimolar_millisecond">
<unit units="millimolar" exponent="-1"/>
<unit units="millisecond" exponent="-1"/>
</units>
<units name="mN_per_mm2">
<unit units="newton" prefix="milli"/>
<unit units="metre" prefix="milli" exponent="-2"/>
</units>
<units name="mN_per_mm2_micrometre">
<unit units="mN_per_mm2"/>
<unit units="micrometre" exponent="-1"/>
</units>
<units name="mN_per_mm2_micrometre5">
<unit units="mN_per_mm2"/>
<unit units="micrometre" exponent="-5"/>
</units>
<units name="micrometre">
<unit units="metre" prefix="micro"/>
</units>
<units name="micrometre3">
<unit units="metre" prefix="micro" exponent="3"/>
</units>
<units name="litre_micrometre3">
<unit units="litre"/>
<unit units="micrometre3" exponent="-1"/>
</units>
<units name="millisecond">
<unit units="second" prefix="milli"/>
</units>
<units name="mm">
<unit units="metre" prefix="milli"/>
</units>
<units name="ng">
<unit units="gram" prefix="nano"/>
</units>
<units name="uA">
<unit units="ampere" prefix="micro"/>
</units>
<units name="pA">
<unit units="ampere" prefix="pico"/>
</units>
<units name="K">
<unit units="kelvin"/>
</units>
<units name="nmol">
<unit units="mole" prefix="nano"/>
</units>
<units name="mmsq">
<unit units="mm" exponent="2"/>
</units>
<units name="mmcu">
<unit units="mm" exponent="3"/>
</units>
<units name="mssq">
<unit units="ms" exponent="2"/>
</units>
<units name="mscu">
<unit units="ms" exponent="3"/>
</units>
<units name="mV">
<unit units="volt" prefix="milli"/>
</units>
<units name="mVsq">
<unit units="mV" exponent="2"/>
</units>
<units name="mV_per_ms">
<unit units="mV"/>
<unit units="ms" exponent="-1"/>
</units>
<units name="mS">
<unit units="siemens" prefix="milli"/>
</units>
<units name="mS_per_mmsq">
<unit units="mS"/>
<unit units="mm" exponent="-2"/>
</units>
<units name="mS_per_mm">
<unit units="mS"/>
<unit units="mm" exponent="-1"/>
</units>
<units name="uA_per_mmsq">
<unit units="uA"/>
<unit units="mm" exponent="-2"/>
</units>
<units name="uA_per_mmcu">
<unit units="uA"/>
<unit units="mm" exponent="-3"/>
</units>
<units name="nC">
<unit units="coulomb" prefix="nano"/>
</units>
<units name="uF">
<unit units="farad" prefix="micro"/>
</units>
<units name="uF_per_mmsq">
<unit units="uF"/>
<unit units="mm" exponent="-2"/>
</units>
<units name="mM">
<unit units="nmol"/>
<unit units="mm" exponent="-3"/>
</units>
<units name="mM_per_ms">
<unit units="mM"/>
<unit units="ms" exponent="-1"/>
</units>
<units name="nN">
<unit units="newton" prefix="nano"/>
</units>
<units name="mPa">
<unit units="pascal" prefix="milli"/>
</units>
<units name="pJ">
<unit units="joule" prefix="pico"/>
</units>
<units name="nW">
<unit units="watt" prefix="nano"/>
</units>
<units name="nS">
<unit units="siemens" prefix="nano"/>
</units>
<units name="per_ms">
<unit units="ms" exponent="-1"/>
</units>
<units name="per_mm">
<unit units="mm" exponent="-1"/>
</units>
<units name="per_mV">
<unit units="mV" exponent="-1"/>
</units>
<units name="per_mL">
<unit units="mL" exponent="-1"/>
</units>
<units name="per_mV_per_ms">
<unit units="mV" exponent="-1"/>
<unit units="per_ms"/>
</units>
<units name="per_mM_per_ms">
<unit units="mM" exponent="-1"/>
<unit units="per_ms"/>
</units>
<units name="uA_per_mmsq_per_mM">
<unit units="uA"/>
<unit units="mm" exponent="-2"/>
<unit units="mM" exponent="-1"/>
</units>
<units name="mm_per_ms">
<unit units="mm"/>
<unit units="per_ms"/>
</units>
<units name="gas_constant">
<unit units="pJ"/>
<unit units="nmol" exponent="-1"/>
<unit units="K" exponent="-1"/>
</units>
<units name="faradays_constant">
<unit units="nC"/>
<unit units="nmol" exponent="-1"/>
</units>
<units name="pA_per_pF">
<unit units="ampere" prefix="pico"/>
<unit units="farad" prefix="pico" exponent="-1"/>
</units>
<units name="nS_per_pF">
<unit units="siemens" prefix="nano"/>
<unit units="farad" prefix="pico" exponent="-1"/>
</units>
<units name="uF_per_cmsq">
<unit units="farad" prefix="micro"/>
<unit units="metre" prefix="centi" exponent="-2"/>
</units>
<units name="um">
<unit units="metre" prefix="micro"/>
</units>
<units name="umsq">
<unit units="metre" prefix="micro" exponent="2"/>
</units>
<units name="umcu">
<unit units="metre" prefix="micro" exponent="3"/>
</units>
<units name="cmcu_per_uF_per_s">
<unit units="metre" prefix="centi" exponent="3"/>
<unit units="farad" prefix="micro" exponent="-1"/>
<unit units="second" exponent="-1"/>
</units>
<units name="mmcu_per_uF_per_ms">
<unit units="metre" prefix="milli" exponent="3"/>
<unit units="farad" prefix="micro" exponent="-1"/>
<unit units="second" prefix="milli" exponent="-1"/>
</units>
<units name="mM_per_s">
<unit units="mM"/>
<unit units="second" exponent="-1"/>
</units>
<units name="elastance">
<unit units="pascal" multiplier="133.322"/>
<unit units="litre" prefix="milli" exponent="-1"/>
</units>
<units name="s">
<unit units="second"/>
</units>
<units name="Hz">
<unit units="s" exponent="-1"/>
</units>
<units name="flow">
<unit units="litre" prefix="milli"/>
<unit units="second" exponent="-1"/>
</units>
<units name="inductance">
<unit units="mmHg"/>
<unit units="s" exponent="2"/>
<unit units="mL" exponent="-1"/>
</units>
<units name="capacitance">
<unit units="mL"/>
<unit units="mmHg" exponent="-1"/>
</units>
<units name="concentration">
<unit units="mL"/>
<unit units="mL" exponent="-1"/>
</units>
<units name="ratepm">
<unit units="second" exponent="-1" multiplier="60"/>
</units>
<units name="Hz2rpm">
<unit units="Hz" exponent="-1"/>
<unit units="ratepm"/>
</units>
<units name="unitconvert">
<unit units="dimensionless"/>
</units>
<units name="mL_per_mole">
<unit units="mL"/>
<unit units="mole" exponent="-1"/>
</units>
<units name="cmH2O_sec2_per_L2">
<unit units="cmH2O"/>
<unit units="second"/>
<unit units="liter" exponent="-2"/>
</units>
<units name="cmH2O_sec_per_L">
<unit units="cmH2O"/>
<unit units="second"/>
<unit units="liter" exponent="-1"/>
</units>
<units name="mL_per_s">
<unit units="mL"/>
<unit units="second" exponent="-1"/>
</units>
<units name="mole_per_min">
<unit units="mole"/>
<unit units="minute" exponent="-1"/>
</units>
<units name="mL_per_min">
<unit units="mL"/>
<unit units="minute" exponent="-1"/>
</units>
<units name="mlSTPD_per_s_per_mmHg4">
<unit units="mlSTPD"/>
<unit units="second" exponent="-1"/>
<unit units="per_mmHg" exponent="4"/>
</units>
<units name="mlSTPD_per_s_per_mmHg3">
<unit units="mlSTPD"/>
<unit units="second" exponent="-1"/>
<unit units="per_mmHg" exponent="3"/>
</units>
<units name="mlSTPD_per_s_per_mmHg2">
<unit units="mlSTPD"/>
<unit units="second" exponent="-1"/>
<unit units="per_mmHg" exponent="2"/>
</units>
<units name="mlSTPD_per_s_per_mmHg">
<unit units="mlSTPD"/>
<unit units="second" exponent="-1"/>
<unit units="per_mmHg"/>
</units>
<units name="mole_per_mmHg">
<unit units="mole"/>
<unit units="per_mmHg"/>
</units>
<units name="per_mmHg">
<unit units="mmHg" exponent="-1"/>
</units>
<units name="cmH2O">
<unit units="pascal" multiplier="0.0102"/>
</units>
<units name="mmHg">
<unit units="pascal" multiplier="133.322"/>
</units>
<units name="Respresistance">
<unit units="cmH2O"/>
<unit units="second"/>
<unit units="litre" exponent="-1"/>
</units>
<units name="CVresistance">
<unit units="mmHg"/>
<unit units="s"/>
<unit units="mL" exponent="-1"/>
</units>
<units name="L">
<unit units="litre"/>
</units>
<units name="minute">
<unit units="second" multiplier="60"/>
</units>
<units name="per_min">
<unit units="minute" exponent="-1"/>
</units>
<units name="L_per_cmH2O">
<unit units="L"/>
<unit units="cmH2O" exponent="-1"/>
</units>
<units name="per_L">
<unit units="L" exponent="-1"/>
</units>
<units name="cmH2O_s2_per_L2">
<unit units="cmH2O"/>
<unit units="second" exponent="2"/>
<unit units="L" exponent="-2"/>
</units>
<units name="L_per_sec">
<unit units="L"/>
<unit units="second" exponent="-1"/>
</units>
<units name="mlSTPD">
<unit units="mole" exponent="-1" multiplier="22400"/>
</units>
<units name="liter_per_min">
<unit units="liter"/>
<unit units="minute" exponent="-1"/>
</units>
<units name="mL">
<unit units="liter" prefix="milli"/>
</units>
<units name="ms">
<unit units="second" prefix="milli"/>
</units>
<component name="SAmembrane">
<variable name="V" units="millivolt" initial_value="-25.9148656754081" public_interface="out"/>
<variable name="R" units="joule_per_mole_kelvin" initial_value="8.3143" public_interface="out"/>
<variable name="T" units="kelvin" initial_value="310" public_interface="out"/>
<variable name="F" units="coulomb_per_millimole" initial_value="96.4867" public_interface="out"/>
<variable name="Cm" units="picoF" initial_value="56" public_interface="out"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="i_Na" units="picoA" public_interface="in"/>
<variable name="i_K1" units="picoA" public_interface="in"/>
<variable name="i_to" units="picoA" public_interface="in"/>
<variable name="i_Kur" units="picoA" public_interface="in"/>
<variable name="i_Kr" units="picoA" public_interface="in"/>
<variable name="i_Ks" units="picoA" public_interface="in"/>
<variable name="i_Ca_L" units="picoA" public_interface="in"/>
<variable name="i_CaP" units="picoA" public_interface="in"/>
<variable name="i_NaK" units="picoA" public_interface="in"/>
<variable name="i_NaCa" units="picoA" public_interface="in"/>
<variable name="i_B_Na" units="picoA" public_interface="in"/>
<variable name="i_B_Ca" units="picoA" public_interface="in"/>
<variable name="i_Ca_T" units="picoA" public_interface="in"/>
<variable name="i_f" units="picoA" public_interface="in"/>
<variable name="i_KACh" units="picoA" public_interface="in"/>
<variable name="Total_current" units="picoA"/>
<variable name="ISAout" units="uA_per_mmsq" public_interface="out"/>
<variable name="ISAout_atrium" units="uA_per_mmsq" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ISAout</ci>
<piecewise>
<piece>
<apply>
<minus/>
<cn cellml:units="uA_per_mmsq">0.5</cn>
</apply>
<apply>
<lt/>
<ci>Total_current</ci>
<apply>
<minus/>
<cn cellml:units="picoA">20</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="uA_per_mmsq">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ISAout_atrium</ci>
<piecewise>
<piece>
<apply>
<minus/>
<cn cellml:units="uA_per_mmsq">0.5</cn>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>Total_current</ci>
<apply>
<minus/>
<cn cellml:units="picoA">2</cn>
</apply>
</apply>
<apply>
<gt/>
<ci>Total_current</ci>
<apply>
<minus/>
<cn cellml:units="picoA">3</cn>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<cn cellml:units="millivolt">0</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="uA_per_mmsq">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>Total_current</ci>
<apply>
<plus/>
<ci>i_Na</ci>
<ci>i_K1</ci>
<ci>i_to</ci>
<ci>i_Kur</ci>
<ci>i_Kr</ci>
<ci>i_Ks</ci>
<ci>i_B_Na</ci>
<ci>i_B_Ca</ci>
<ci>i_NaK</ci>
<ci>i_CaP</ci>
<ci>i_NaCa</ci>
<ci>i_Ca_L</ci>
<ci>i_Ca_T</ci>
<ci>i_f</ci>
<ci>i_KACh</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Total_current</ci>
</apply>
<ci>Cm</ci>
</apply>
</apply>
</math>
</component>
<component name="fast_sodium_current">
<variable name="i_Na" units="picoA" public_interface="out"/>
<variable name="E_Na" units="millivolt" public_interface="out"/>
<variable name="g_Na" units="nanoS_per_picoF" initial_value="0.234"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="Na_i" units="millimolar" public_interface="in"/>
<variable name="Na_o" units="millimolar" public_interface="in"/>
<variable name="R" units="joule_per_mole_kelvin" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<variable name="T" units="kelvin" public_interface="in"/>
<variable name="m" units="dimensionless" private_interface="in"/>
<variable name="h" units="dimensionless" private_interface="in"/>
<variable name="j" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Na</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_Na</ci>
<apply>
<power/>
<ci>m</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>h</ci>
<ci>j</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E_Na</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Na_o</ci>
<ci>Na_i</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="fast_sodium_current_m_gate">
<variable name="m" units="dimensionless" initial_value="0.901589232313455" public_interface="out"/>
<variable name="alpha_m" units="per_millisecond"/>
<variable name="beta_m" units="per_millisecond"/>
<variable name="m_inf" units="dimensionless"/>
<variable name="tau_m" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_m</ci>
<piecewise>
<piece>
<cn cellml:units="per_millisecond">3.2</cn>
<apply>
<eq/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">47.13</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_millisecond">0.32</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">47.13</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.1</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">47.13</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_m</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.08</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="millivolt">11</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>m_inf</ci>
<apply>
<divide/>
<ci>alpha_m</ci>
<apply>
<plus/>
<ci>alpha_m</ci>
<ci>beta_m</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_m</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_m</ci>
<ci>beta_m</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>m</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>m_inf</ci>
<ci>m</ci>
</apply>
<ci>tau_m</ci>
</apply>
</apply>
</math>
</component>
<component name="fast_sodium_current_h_gate">
<variable name="h" units="dimensionless" initial_value="0" public_interface="out"/>
<variable name="alpha_h" units="per_millisecond"/>
<variable name="beta_h" units="per_millisecond"/>
<variable name="h_inf" units="dimensionless"/>
<variable name="tau_h" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_h</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.135</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">80</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">6.8</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="per_millisecond">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_h</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="per_millisecond">3.56</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.079</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn type="e-notation" cellml:units="per_millisecond">3.1 <sep/>
5</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.35</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="millisecond">0.13</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10.66</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">11.1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>h_inf</ci>
<apply>
<divide/>
<ci>alpha_h</ci>
<apply>
<plus/>
<ci>alpha_h</ci>
<ci>beta_h</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_h</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_h</ci>
<ci>beta_h</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>h</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>h_inf</ci>
<ci>h</ci>
</apply>
<ci>tau_h</ci>
</apply>
</apply>
</math>
</component>
<component name="fast_sodium_current_j_gate">
<variable name="j" units="dimensionless" initial_value="5.85587871502196e-69" public_interface="out"/>
<variable name="alpha_j" units="per_millisecond"/>
<variable name="beta_j" units="per_millisecond"/>
<variable name="j_inf" units="dimensionless"/>
<variable name="tau_j" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_j</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<minus/>
<cn type="e-notation" cellml:units="per_millivolt_millisecond">1.2714 <sep/>
5</cn>
</apply>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.2444</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn type="e-notation" cellml:units="per_millivolt_millisecond">3.474 <sep/>
-5</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.04391</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">37.78</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.311</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">79.23</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="per_millisecond">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_j</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.1212</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.01052</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.1378</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">40.14</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.3</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn type="e-notation" cellml:units="per_millivolt">2.535 <sep/>
-7</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_millivolt">0.1</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">32</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>j_inf</ci>
<apply>
<divide/>
<ci>alpha_j</ci>
<apply>
<plus/>
<ci>alpha_j</ci>
<ci>beta_j</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_j</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_j</ci>
<ci>beta_j</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>j</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>j_inf</ci>
<ci>j</ci>
</apply>
<ci>tau_j</ci>
</apply>
</apply>
</math>
</component>
<component name="time_independent_potassium_current">
<variable name="i_K1" units="picoA" public_interface="out"/>
<variable name="E_K" units="millivolt" public_interface="out"/>
<variable name="g_K1" units="nanoS_per_picoF" initial_value="0.01665"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="K_o" units="millimolar" public_interface="in"/>
<variable name="R" units="joule_per_mole_kelvin" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<variable name="T" units="kelvin" public_interface="in"/>
<variable name="K_i" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>E_K</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>K_o</ci>
<ci>K_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_K1</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_K1</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.07</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">80</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="transient_outward_K_current">
<variable name="i_to" units="picoA" public_interface="out"/>
<variable name="K_Q10" units="dimensionless" initial_value="3" public_interface="out" private_interface="out"/>
<variable name="g_to" units="nanoS_per_picoF" initial_value="0.009912"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="E_K" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="oa" units="dimensionless" private_interface="in"/>
<variable name="oi" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_to</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_to</ci>
<apply>
<power/>
<ci>oa</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>oi</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="transient_outward_K_current_oa_gate">
<variable name="oa" units="dimensionless" initial_value="0.430553108241678" public_interface="out"/>
<variable name="alpha_oa" units="per_millisecond"/>
<variable name="beta_oa" units="per_millisecond"/>
<variable name="tau_oa" units="millisecond"/>
<variable name="oa_infinity" units="dimensionless"/>
<variable name="K_Q10" units="dimensionless" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_oa</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.65</cn>
<apply>
<power/>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">8.5</cn>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">40</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">59</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_oa</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.65</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">2.5</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">72</cn>
</apply>
<cn cellml:units="millivolt">17</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_oa</ci>
<apply>
<divide/>
<apply>
<power/>
<apply>
<plus/>
<ci>alpha_oa</ci>
<ci>beta_oa</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<ci>K_Q10</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>oa_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">10.47</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">17.54</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>oa</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>oa_infinity</ci>
<ci>oa</ci>
</apply>
<ci>tau_oa</ci>
</apply>
</apply>
</math>
</component>
<component name="transient_outward_K_current_oi_gate">
<variable name="oi" units="dimensionless" initial_value="0.0242020122101775" public_interface="out"/>
<variable name="alpha_oi" units="per_millisecond"/>
<variable name="beta_oi" units="per_millisecond"/>
<variable name="tau_oi" units="millisecond"/>
<variable name="oi_infinity" units="dimensionless"/>
<variable name="K_Q10" units="dimensionless" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_oi</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="millisecond">18.53</cn>
<apply>
<times/>
<cn cellml:units="millisecond">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">103.7</cn>
</apply>
<cn cellml:units="millivolt">10.95</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_oi</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="millisecond">35.56</cn>
<apply>
<times/>
<cn cellml:units="millisecond">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">8.74</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">7.44</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_oi</ci>
<apply>
<divide/>
<apply>
<power/>
<apply>
<plus/>
<ci>alpha_oi</ci>
<ci>beta_oi</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<ci>K_Q10</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>oi_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">33.1</cn>
</apply>
<cn cellml:units="millivolt">5.3</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>oi</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>oi_infinity</ci>
<ci>oi</ci>
</apply>
<ci>tau_oi</ci>
</apply>
</apply>
</math>
</component>
<component name="ultrarapid_delayed_rectifier_K_current">
<variable name="i_Kur" units="picoA" public_interface="out"/>
<variable name="g_Kur" units="nanoS_per_picoF"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="E_K" units="millivolt" public_interface="in"/>
<variable name="K_Q10" units="dimensionless" public_interface="in" private_interface="out"/>
<variable name="ua" units="dimensionless" private_interface="in"/>
<variable name="ui" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_Kur</ci>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="nanoS_per_picoF">0.005</cn>
<apply>
<divide/>
<cn cellml:units="nanoS_per_picoF">0.05</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">15</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">13</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">0.13</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>i_Kur</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_Kur</ci>
<apply>
<power/>
<ci>ua</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>ui</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ultrarapid_delayed_rectifier_K_current_ua_gate">
<variable name="ua" units="dimensionless" initial_value="0.625416278545545" public_interface="out"/>
<variable name="alpha_ua" units="per_millisecond"/>
<variable name="beta_ua" units="per_millisecond"/>
<variable name="tau_ua" units="millisecond"/>
<variable name="ua_infinity" units="dimensionless"/>
<variable name="K_Q10" units="dimensionless" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_ua</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.65</cn>
<apply>
<power/>
<apply>
<plus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">8.5</cn>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">40</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">59</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_ua</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.65</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">2.5</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">72</cn>
</apply>
<cn cellml:units="millivolt">17</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_ua</ci>
<apply>
<divide/>
<apply>
<power/>
<apply>
<plus/>
<ci>alpha_ua</ci>
<ci>beta_ua</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<ci>K_Q10</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ua_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">20.3</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">9.6</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ua</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ua_infinity</ci>
<ci>ua</ci>
</apply>
<ci>tau_ua</ci>
</apply>
</apply>
</math>
</component>
<component name="ultrarapid_delayed_rectifier_K_current_ui_gate">
<variable name="ui" units="dimensionless" initial_value="0.976295453694032" public_interface="out"/>
<variable name="alpha_ui" units="per_millisecond"/>
<variable name="beta_ui" units="per_millisecond"/>
<variable name="tau_ui" units="millisecond"/>
<variable name="ui_infinity" units="dimensionless"/>
<variable name="K_Q10" units="dimensionless" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_ui</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="millisecond">21</cn>
<apply>
<times/>
<cn cellml:units="millisecond">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">195</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_ui</ci>
<apply>
<divide/>
<cn cellml:units="per_millisecond">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">168</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">16</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_ui</ci>
<apply>
<divide/>
<apply>
<power/>
<apply>
<plus/>
<ci>alpha_ui</ci>
<ci>beta_ui</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<ci>K_Q10</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ui_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn cellml:units="millivolt">109.45</cn>
</apply>
<cn cellml:units="millivolt">27.48</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ui</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ui_infinity</ci>
<ci>ui</ci>
</apply>
<ci>tau_ui</ci>
</apply>
</apply>
</math>
</component>
<component name="rapid_delayed_rectifier_K_current">
<variable name="i_Kr" units="picoA" public_interface="out"/>
<variable name="g_Kr" units="nanoS_per_picoF" initial_value="0.0057615"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="E_K" units="millivolt" public_interface="in"/>
<variable name="xr" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Kr</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_Kr</ci>
<ci>xr</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">15</cn>
</apply>
<cn cellml:units="millivolt">22.4</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="rapid_delayed_rectifier_K_current_xr_gate">
<variable name="xr" units="dimensionless" initial_value="0.675224460789614" public_interface="out"/>
<variable name="alpha_xr" units="per_millisecond"/>
<variable name="beta_xr" units="per_millisecond"/>
<variable name="tau_xr" units="millisecond"/>
<variable name="xr_infinity" units="dimensionless"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_xr</ci>
<piecewise>
<piece>
<cn cellml:units="per_millisecond">0.0015</cn>
<apply>
<lt/>
<apply>
<abs/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">14.1</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="millivolt">1 <sep/>
-10</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_millisecond">0.0003</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">14.1</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">14.1</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_xr</ci>
<piecewise>
<piece>
<cn type="e-notation" cellml:units="per_millisecond">3.7836118 <sep/>
-4</cn>
<apply>
<lt/>
<apply>
<abs/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">3.3328</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="millivolt">1 <sep/>
-10</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_millisecond">0.000073898</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">3.3328</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">3.3328</cn>
</apply>
<cn cellml:units="millivolt">5.1237</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_xr</ci>
<apply>
<power/>
<apply>
<plus/>
<ci>alpha_xr</ci>
<ci>beta_xr</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>xr_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">14.1</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">6.5</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xr</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xr_infinity</ci>
<ci>xr</ci>
</apply>
<ci>tau_xr</ci>
</apply>
</apply>
</math>
</component>
<component name="slow_delayed_rectifier_K_current">
<variable name="i_Ks" units="picoA" public_interface="out"/>
<variable name="g_Ks" units="nanoS_per_picoF" initial_value="0.0064505"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="E_K" units="millivolt" public_interface="in"/>
<variable name="xs" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Ks</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_Ks</ci>
<apply>
<power/>
<ci>xs</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="slow_delayed_rectifier_K_current_xs_gate">
<variable name="xs" units="dimensionless" initial_value="0.266144350665511" public_interface="out"/>
<variable name="alpha_xs" units="per_millisecond"/>
<variable name="beta_xs" units="per_millisecond"/>
<variable name="tau_xs" units="millisecond"/>
<variable name="xs_infinity" units="dimensionless"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_xs</ci>
<piecewise>
<piece>
<cn cellml:units="per_millisecond">0.00068</cn>
<apply>
<lt/>
<apply>
<abs/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="millivolt">1 <sep/>
-10</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_millisecond">0.00004</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">17</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_xs</ci>
<piecewise>
<piece>
<cn cellml:units="per_millisecond">0.000315</cn>
<apply>
<lt/>
<apply>
<abs/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="millivolt">1 <sep/>
-10</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millivolt_millisecond">0.000035</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
<cn cellml:units="millivolt">9</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_xs</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<apply>
<power/>
<apply>
<plus/>
<ci>alpha_xs</ci>
<ci>beta_xs</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>xs_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">19.9</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">12.7</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">0.5</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xs</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>xs_infinity</ci>
<ci>xs</ci>
</apply>
<ci>tau_xs</ci>
</apply>
</apply>
</math>
</component>
<component name="L_type_Ca_channel">
<variable name="i_Ca_L" units="picoA" public_interface="out"/>
<variable name="g_Ca_L" units="nanoS_per_picoF" initial_value="0.085"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="Ca_i" units="millimolar" public_interface="in" private_interface="out"/>
<variable name="d" units="dimensionless" private_interface="in"/>
<variable name="f" units="dimensionless" private_interface="in"/>
<variable name="f_Ca" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Ca_L</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_Ca_L</ci>
<ci>d</ci>
<ci>f</ci>
<ci>f_Ca</ci>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">65</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="L_type_Ca_channel_d_gate">
<variable name="d" units="dimensionless" initial_value="0.123573126723491" public_interface="out"/>
<variable name="d_infinity" units="dimensionless"/>
<variable name="tau_d" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>d_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">8</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="millisecond">4.579</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">6.24</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<apply>
<abs/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="millivolt">1 <sep/>
-10</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">6.24</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="per_millivolt_millisecond">0.035</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">6.24</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_infinity</ci>
<ci>d</ci>
</apply>
<ci>tau_d</ci>
</apply>
</apply>
</math>
</component>
<component name="L_type_Ca_channel_f_gate">
<variable name="f" units="dimensionless" initial_value="0.202169843956322" public_interface="out"/>
<variable name="f_infinity" units="dimensionless"/>
<variable name="tau_f" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>f_infinity</ci>
<apply>
<divide/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6.9</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">28</cn>
</apply>
</apply>
<cn cellml:units="millivolt">6.9</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_f</ci>
<apply>
<times/>
<cn cellml:units="millisecond">9</cn>
<apply>
<power/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0197</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<power/>
<cn cellml:units="per_millivolt">0.0337</cn>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">10</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">0.02</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_infinity</ci>
<ci>f</ci>
</apply>
<ci>tau_f</ci>
</apply>
</apply>
</math>
</component>
<component name="L_type_Ca_channel_f_Ca_gate">
<variable name="f_Ca" units="dimensionless" initial_value="0.331673604593916" public_interface="out"/>
<variable name="f_Ca_infinity" units="dimensionless"/>
<variable name="tau_f_Ca" units="millisecond"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>f_Ca_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>Ca_i</ci>
<cn cellml:units="millimolar">0.00035</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_f_Ca</ci>
<cn cellml:units="millisecond">2</cn>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f_Ca</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_Ca_infinity</ci>
<ci>f_Ca</ci>
</apply>
<ci>tau_f_Ca</ci>
</apply>
</apply>
</math>
</component>
<component name="sodium_potassium_pump">
<variable name="i_NaK" units="picoA" public_interface="out"/>
<variable name="Km_Na_i" units="millimolar" initial_value="10"/>
<variable name="Km_K_o" units="millimolar" initial_value="1.5"/>
<variable name="i_NaK_max" units="picoA_per_picoF" initial_value="0.3"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="f_NaK" units="dimensionless"/>
<variable name="sigma" units="dimensionless"/>
<variable name="K_o" units="millimolar" public_interface="in"/>
<variable name="Na_i" units="millimolar" public_interface="in"/>
<variable name="Na_o" units="millimolar" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="R" units="joule_per_mole_kelvin" public_interface="in"/>
<variable name="T" units="kelvin" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>sigma</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">7</cn>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Na_o</ci>
<cn cellml:units="millimolar">67.3</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>f_NaK</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.1245</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">0.1</cn>
</apply>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0365</cn>
<ci>sigma</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>F</ci>
</apply>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_NaK</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Cm</ci>
<ci>i_NaK_max</ci>
<ci>f_NaK</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Km_Na_i</ci>
<ci>Na_i</ci>
</apply>
<cn cellml:units="dimensionless">1.5</cn>
</apply>
</apply>
</apply>
<ci>K_o</ci>
</apply>
<apply>
<plus/>
<ci>K_o</ci>
<ci>Km_K_o</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="background_currents">
<variable name="i_B_Na" units="picoA" public_interface="out"/>
<variable name="i_B_Ca" units="picoA" public_interface="out"/>
<variable name="i_B_K" units="picoA" public_interface="out"/>
<variable name="g_B_Na" units="nanoS_per_picoF" initial_value="0.000335"/>
<variable name="g_B_Ca" units="nanoS_per_picoF" initial_value="0.0004565"/>
<variable name="g_B_K" units="nanoS_per_picoF" initial_value="1e-5"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="E_Ca" units="millivolt"/>
<variable name="E_K" units="millivolt" public_interface="in"/>
<variable name="E_Na" units="millivolt" public_interface="in"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<variable name="Ca_o" units="millimolar" public_interface="in"/>
<variable name="R" units="joule_per_mole_kelvin" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<variable name="T" units="kelvin" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>E_Ca</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Ca_o</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_B_Na</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_B_Na</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_B_Ca</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_B_Ca</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ca</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_B_K</ci>
<apply>
<times/>
<ci>Cm</ci>
<ci>g_B_K</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Na_Ca_exchanger_current">
<variable name="i_NaCa" units="picoA" public_interface="out"/>
<variable name="I_NaCa_max" units="picoA_per_picoF" initial_value="588.8"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="K_mNa" units="millimolar" initial_value="87.5"/>
<variable name="K_mCa" units="millimolar" initial_value="1.38"/>
<variable name="K_sat" units="dimensionless" initial_value="0.1"/>
<variable name="gamma" units="dimensionless" initial_value="0.35"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="R" units="joule_per_mole_kelvin" public_interface="in"/>
<variable name="T" units="kelvin" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<variable name="Na_i" units="millimolar" public_interface="in"/>
<variable name="Na_o" units="millimolar" public_interface="in"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<variable name="Ca_o" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_NaCa</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Cm</ci>
<ci>I_NaCa_max</ci>
<apply>
<minus/>
<apply>
<times/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>gamma</ci>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<power/>
<ci>Na_i</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Ca_o</ci>
</apply>
<apply>
<times/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>gamma</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
<ci>F</ci>
<ci>V</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<power/>
<ci>K_mNa</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<plus/>
<ci>K_mCa</ci>
<ci>Ca_o</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<ci>K_sat</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>gamma</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="sarcolemmal_calcium_pump_current">
<variable name="i_CaP" units="picoA" public_interface="out"/>
<variable name="i_CaP_max" units="picoA_per_picoF" initial_value="0.1375"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_CaP</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Cm</ci>
<ci>i_CaP_max</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="millimolar">0.0005</cn>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Ca_release_current_from_JSR">
<variable name="i_rel" units="millimolar_per_millisecond" public_interface="out"/>
<variable name="Fn" units="dimensionless" private_interface="out"/>
<variable name="K_rel" units="per_millisecond" initial_value="9.33"/>
<variable name="V_rel" units="micrometre_3" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<variable name="Ca_rel" units="millimolar" public_interface="in"/>
<variable name="i_Ca_L" units="picoA" public_interface="in"/>
<variable name="i_NaCa" units="picoA" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<variable name="u" units="dimensionless" private_interface="in"/>
<variable name="v" units="dimensionless" private_interface="in"/>
<variable name="w" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Fn</ci>
<apply>
<times/>
<cn type="e-notation" cellml:units="millisecond_per_millimolar">1 <sep/>
3</cn>
<apply>
<minus/>
<apply>
<times/>
<cn type="e-notation" cellml:units="per_micrometre_3">1 <sep/>
-15</cn>
<ci>V_rel</ci>
<ci>i_rel</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<cn type="e-notation" cellml:units="per_micrometre_3">1 <sep/>
-15</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>F</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>i_Ca_L</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.2</cn>
<ci>i_NaCa</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>i_rel</ci>
<apply>
<times/>
<ci>K_rel</ci>
<apply>
<power/>
<ci>u</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>v</ci>
<ci>w</ci>
<apply>
<minus/>
<ci>Ca_rel</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Ca_release_current_from_JSR_u_gate">
<variable name="u" units="dimensionless" initial_value="-2.2569975184225e-35" public_interface="out"/>
<variable name="tau_u" units="millisecond"/>
<variable name="u_infinity" units="dimensionless"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="Fn" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>tau_u</ci>
<cn cellml:units="millisecond">8</cn>
</apply>
<apply>
<eq/>
<ci>u_infinity</ci>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Fn</ci>
<cn type="e-notation" cellml:units="dimensionless">3.4175 <sep/>
-13</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">13.67 <sep/>
-16</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>u</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>u_infinity</ci>
<ci>u</ci>
</apply>
<ci>tau_u</ci>
</apply>
</apply>
</math>
</component>
<component name="Ca_release_current_from_JSR_v_gate">
<variable name="v" units="dimensionless" initial_value="0.999999999999999" public_interface="out"/>
<variable name="tau_v" units="millisecond"/>
<variable name="v_infinity" units="dimensionless"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="Fn" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>tau_v</ci>
<apply>
<plus/>
<cn cellml:units="millisecond">1.91</cn>
<apply>
<times/>
<cn cellml:units="millisecond">2.09</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Fn</ci>
<cn type="e-notation" cellml:units="dimensionless">3.4175 <sep/>
-13</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">13.67 <sep/>
-16</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_infinity</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Fn</ci>
<cn type="e-notation" cellml:units="dimensionless">6.835 <sep/>
-14</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">13.67 <sep/>
-16</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>v</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>v_infinity</ci>
<ci>v</ci>
</apply>
<ci>tau_v</ci>
</apply>
</apply>
</math>
</component>
<component name="Ca_release_current_from_JSR_w_gate">
<variable name="w" units="dimensionless" initial_value="0.979607422520652" public_interface="out"/>
<variable name="tau_w" units="millisecond"/>
<variable name="w_infinity" units="dimensionless"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>tau_w</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millisecond">6</cn>
<cn cellml:units="dimensionless">0.2</cn>
</apply>
<cn cellml:units="dimensionless">1.3</cn>
</apply>
<apply>
<lt/>
<apply>
<abs/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">7.9</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="millivolt">1 <sep/>
-10</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="millisecond">6</cn>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">7.9</cn>
</apply>
</apply>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.3</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">7.9</cn>
</apply>
</apply>
<cn cellml:units="millivolt">5</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="per_millivolt">1</cn>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">7.9</cn>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>w_infinity</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
<cn cellml:units="millivolt">17</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>w</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>w_infinity</ci>
<ci>w</ci>
</apply>
<ci>tau_w</ci>
</apply>
</apply>
</math>
</component>
<component name="transfer_current_from_NSR_to_JSR">
<variable name="i_tr" units="millimolar_per_millisecond" public_interface="out"/>
<variable name="tau_tr" units="millisecond" initial_value="180"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="Ca_rel" units="millimolar" public_interface="in"/>
<variable name="Ca_up" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_tr</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>Ca_up</ci>
<ci>Ca_rel</ci>
</apply>
<ci>tau_tr</ci>
</apply>
</apply>
</math>
</component>
<component name="Ca_uptake_current_by_the_NSR">
<variable name="I_up_max" units="millimolar_per_millisecond" initial_value="0.00152" public_interface="out"/>
<variable name="i_up" units="millimolar_per_millisecond" public_interface="out"/>
<variable name="K_up" units="millimolar" initial_value="0.00092"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_up</ci>
<apply>
<divide/>
<ci>I_up_max</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>K_up</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Ca_leak_current_by_the_NSR">
<variable name="i_up_leak" units="millimolar_per_millisecond" public_interface="out"/>
<variable name="Ca_up_max" units="millimolar" initial_value="15"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="Ca_up" units="millimolar" public_interface="in"/>
<variable name="I_up_max" units="millimolar_per_millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_up_leak</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>I_up_max</ci>
<ci>Ca_up</ci>
</apply>
<ci>Ca_up_max</ci>
</apply>
</apply>
</math>
</component>
<component name="Ca_buffers">
<variable name="CMDN_max" units="millimolar" initial_value="0.05" public_interface="out"/>
<variable name="TRPN_max" units="millimolar" initial_value="0.07" public_interface="out"/>
<variable name="CSQN_max" units="millimolar" initial_value="10" public_interface="out"/>
<variable name="Km_CMDN" units="millimolar" initial_value="0.00238" public_interface="out"/>
<variable name="Km_TRPN" units="millimolar" initial_value="0.0005" public_interface="out"/>
<variable name="Km_CSQN" units="millimolar" initial_value="0.8" public_interface="out"/>
<variable name="Ca_CMDN" units="millimolar"/>
<variable name="Ca_TRPN" units="millimolar"/>
<variable name="Ca_CSQN" units="millimolar"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="Ca_i" units="millimolar" public_interface="in"/>
<variable name="Ca_rel" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ca_CMDN</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>CMDN_max</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<plus/>
<ci>Ca_i</ci>
<ci>Km_CMDN</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Ca_TRPN</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>TRPN_max</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<plus/>
<ci>Ca_i</ci>
<ci>Km_TRPN</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Ca_CSQN</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>CSQN_max</ci>
<ci>Ca_rel</ci>
</apply>
<apply>
<plus/>
<ci>Ca_rel</ci>
<ci>Km_CSQN</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="intracellular_ion_concentrations">
<variable name="Na_i" units="millimolar" initial_value="10.4206812143853" public_interface="out"/>
<variable name="Ca_i" units="millimolar" initial_value="0.00070499338653051" public_interface="out"/>
<variable name="K_i" units="millimolar" initial_value="167.146227880574" public_interface="out"/>
<variable name="Ca_rel" units="millimolar" initial_value="6.3028172139674" public_interface="out"/>
<variable name="Ca_up" units="millimolar" initial_value="6.30546055912018" public_interface="out"/>
<variable name="V_cell" units="micrometre_3" initial_value="20100"/>
<variable name="V_i" units="micrometre_3"/>
<variable name="V_rel" units="micrometre_3" public_interface="out"/>
<variable name="V_up" units="micrometre_3"/>
<variable name="B1" units="millimolar_per_millisecond"/>
<variable name="B2" units="dimensionless"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="F" units="coulomb_per_millimole" public_interface="in"/>
<variable name="i_NaK" units="picoA" public_interface="in"/>
<variable name="i_NaCa" units="picoA" public_interface="in"/>
<variable name="i_B_Na" units="picoA" public_interface="in"/>
<variable name="i_Na" units="picoA" public_interface="in"/>
<variable name="i_K1" units="picoA" public_interface="in"/>
<variable name="i_to" units="picoA" public_interface="in"/>
<variable name="i_Kur" units="picoA" public_interface="in"/>
<variable name="i_Kr" units="picoA" public_interface="in"/>
<variable name="i_Ks" units="picoA" public_interface="in"/>
<variable name="i_CaP" units="picoA" public_interface="in"/>
<variable name="i_Ca_L" units="picoA" public_interface="in"/>
<variable name="i_B_Ca" units="picoA" public_interface="in"/>
<variable name="i_B_K" units="picoA" public_interface="in"/>
<variable name="i_up" units="millimolar_per_millisecond" public_interface="in"/>
<variable name="i_up_leak" units="millimolar_per_millisecond" public_interface="in"/>
<variable name="i_tr" units="millimolar_per_millisecond" public_interface="in"/>
<variable name="i_rel" units="millimolar_per_millisecond" public_interface="in"/>
<variable name="Km_CMDN" units="millimolar" public_interface="in"/>
<variable name="Km_CSQN" units="millimolar" public_interface="in"/>
<variable name="Km_TRPN" units="millimolar" public_interface="in"/>
<variable name="CMDN_max" units="millimolar" public_interface="in"/>
<variable name="CSQN_max" units="millimolar" public_interface="in"/>
<variable name="TRPN_max" units="millimolar" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>V_i</ci>
<apply>
<times/>
<ci>V_cell</ci>
<cn cellml:units="dimensionless">0.68</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>V_rel</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0048</cn>
<ci>V_cell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>V_up</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0552</cn>
<ci>V_cell</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Na_i</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>i_NaK</ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>i_NaCa</ci>
</apply>
<ci>i_B_Na</ci>
<ci>i_Na</ci>
</apply>
</apply>
<apply>
<times/>
<ci>V_i</ci>
<ci>F</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>K_i</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>i_NaK</ci>
</apply>
<apply>
<plus/>
<ci>i_K1</ci>
<ci>i_to</ci>
<ci>i_Kur</ci>
<ci>i_Kr</ci>
<ci>i_Ks</ci>
<ci>i_B_K</ci>
</apply>
</apply>
<apply>
<times/>
<ci>V_i</ci>
<ci>F</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_i</ci>
</apply>
<apply>
<divide/>
<ci>B1</ci>
<ci>B2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>B1</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>i_NaCa</ci>
</apply>
<apply>
<plus/>
<ci>i_CaP</ci>
<ci>i_Ca_L</ci>
<ci>i_B_Ca</ci>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>V_i</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<ci>V_up</ci>
<apply>
<minus/>
<ci>i_up_leak</ci>
<ci>i_up</ci>
</apply>
</apply>
<apply>
<times/>
<ci>i_rel</ci>
<ci>V_rel</ci>
</apply>
</apply>
<ci>V_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>B2</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>TRPN_max</ci>
<ci>Km_TRPN</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>Ca_i</ci>
<ci>Km_TRPN</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>CMDN_max</ci>
<ci>Km_CMDN</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>Ca_i</ci>
<ci>Km_CMDN</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_up</ci>
</apply>
<apply>
<minus/>
<ci>i_up</ci>
<apply>
<plus/>
<ci>i_up_leak</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>i_tr</ci>
<ci>V_rel</ci>
</apply>
<ci>V_up</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_rel</ci>
</apply>
<apply>
<times/>
<apply>
<minus/>
<ci>i_tr</ci>
<ci>i_rel</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<times/>
<ci>CSQN_max</ci>
<ci>Km_CSQN</ci>
</apply>
<apply>
<power/>
<apply>
<plus/>
<ci>Ca_rel</ci>
<ci>Km_CSQN</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="funny_current">
<variable name="d_f" units="dimensionless" initial_value="0.162509736186646"/>
<variable name="alpha_d_f" units="per_millisecond"/>
<variable name="beta_d_f" units="per_millisecond"/>
<variable name="d_f_infinity" units="dimensionless"/>
<variable name="tau_d_f" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<variable name="i_f" units="picoA" public_interface="out"/>
<variable name="g_f" units="nanoS_per_picoF" initial_value="0.075"/>
<variable name="E_f" units="millivolt" initial_value="-22"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_d_f</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.36</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">148.8</cn>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.066</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">148.8</cn>
</apply>
</apply>
</apply>
<cn cellml:units="millivolt">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_d_f</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.1</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">87.3</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="millivolt">0.21</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">87.3</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d_f</ci>
<apply>
<minus/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_d_f</ci>
<ci>beta_d_f</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">0.054</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>d_f_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_d_f</ci>
<ci>beta_d_f</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d_f</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_f_infinity</ci>
<ci>d_f</ci>
</apply>
<ci>tau_d_f</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>i_f</ci>
<apply>
<times/>
<ci>g_f</ci>
<ci>d_f</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_f</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="T_type_Ca_channel">
<variable name="i_Ca_T" units="picoA" public_interface="out"/>
<variable name="g_Ca_T" units="nanoS_per_picoF" initial_value="0.10914"/>
<variable name="E_Ca_T" units="millivolt" initial_value="45"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="V" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="d_T" units="dimensionless" private_interface="in"/>
<variable name="f_T" units="dimensionless" private_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_Ca_T</ci>
<apply>
<times/>
<ci>g_Ca_T</ci>
<ci>d_T</ci>
<ci>f_T</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ca_T</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="T_type_Ca_channel_d_gate">
<variable name="d_T" units="dimensionless" initial_value="0.516044748800944" public_interface="out"/>
<variable name="alpha_d_T" units="per_millisecond"/>
<variable name="beta_d_T" units="per_millisecond"/>
<variable name="d_T_infinity" units="dimensionless"/>
<variable name="tau_d_T" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_d_T</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">1068</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">26.3</cn>
</apply>
<cn cellml:units="millivolt">30</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_d_T</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">1068</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">26.3</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">30</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d_T</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_d_T</ci>
<ci>beta_d_T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>d_T_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">26.3</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d_T</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_T_infinity</ci>
<ci>d_T</ci>
</apply>
<ci>tau_d_T</ci>
</apply>
</apply>
</math>
</component>
<component name="T_type_Ca_channel_f_gate">
<variable name="f_T" units="dimensionless" initial_value="0.00167482510001593" public_interface="out"/>
<variable name="alpha_f_T" units="per_millisecond"/>
<variable name="beta_f_T" units="per_millisecond"/>
<variable name="f_T_infinity" units="dimensionless"/>
<variable name="tau_f_T" units="millisecond"/>
<variable name="V" units="millivolt" public_interface="in"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_f_T</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">15.3</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">61.7</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="millivolt">83.3</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_f_T</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">15</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">61.7</cn>
</apply>
<cn cellml:units="millivolt">15.38</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_f_T</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_f_T</ci>
<ci>beta_f_T</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>f_T_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="millivolt">61.7</cn>
</apply>
<cn cellml:units="millivolt">5.6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f_T</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_T_infinity</ci>
<ci>f_T</ci>
</apply>
<ci>tau_f_T</ci>
</apply>
</apply>
</math>
</component>
<component name="standard_ionic_concentrations">
<variable name="Na_o" units="millimolar" initial_value="140" public_interface="out"/>
<variable name="Ca_o" units="millimolar" initial_value="1.8" public_interface="out"/>
<variable name="K_o" units="millimolar" initial_value="5.4" public_interface="out"/>
</component>
<component name="ACh_dependent_potassium_current">
<variable name="i_KACh" units="picoA" public_interface="out"/>
<variable name="time" units="millisecond" public_interface="in" private_interface="out"/>
<variable name="Vm" units="millivolt" public_interface="in" private_interface="out"/>
<variable name="E_K" units="millivolt" public_interface="in"/>
<variable name="Cm" units="picoF" public_interface="in"/>
<variable name="y" units="dimensionless" private_interface="in"/>
<variable name="g_ACh" units="nanoS_per_picoF" initial_value="0.25"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>i_KACh</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>g_ACh</ci>
<apply>
<minus/>
<ci>Vm</ci>
<ci>E_K</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>Vm</ci>
<cn cellml:units="millivolt">20</cn>
</apply>
<cn cellml:units="millivolt">20</cn>
</apply>
</apply>
</apply>
</apply>
<ci>y</ci>
</apply>
</apply>
</math>
</component>
<component name="ACh_dependent_potassium_current_y_gate">
<variable name="y" units="dimensionless" initial_value="0.0174987351079082" public_interface="out"/>
<variable name="alpha_y" units="per_millisecond"/>
<variable name="beta_y" units="per_millisecond"/>
<variable name="Vm" units="millivolt" public_interface="in"/>
<variable name="ACh" units="millimolar" initial_value="0"/>
<variable name="Km_ACh" units="millimolar" initial_value="0.0042"/>
<variable name="time" units="millisecond" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>alpha_y</ci>
<piecewise>
<piece>
<cn cellml:units="per_millisecond">0.0002475</cn>
<apply>
<eq/>
<ci>ACh</ci>
<cn cellml:units="millimolar">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="per_millisecond">0.01232</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<ci>Km_ACh</ci>
<ci>ACh</ci>
</apply>
</apply>
</apply>
<cn cellml:units="per_millisecond">0.0002475</cn>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_y</ci>
<apply>
<times/>
<cn cellml:units="per_millisecond">0.01</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_millivolt">0.0133</cn>
<apply>
<plus/>
<ci>Vm</ci>
<cn cellml:units="millivolt">40</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>y</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>alpha_y</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<ci>y</ci>
</apply>
</apply>
<apply>
<times/>
<ci>beta_y</ci>
<ci>y</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="environment">
<variable name="time" units="ms" public_interface="out"/>
<variable name="HR" units="ratepm" initial_value="60" public_interface="out"/>
<variable name="hrf" units="Hz" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>hrf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1000</cn>
<apply>
<divide/>
<ci>HR</ci>
<cn cellml:units="Hz2rpm">60</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="LATiming">
<variable name="realtime" units="ms" public_interface="in"/>
<variable name="HR" units="ratepm" public_interface="in"/>
<variable name="beattime" units="ms" public_interface="out"/>
<variable name="hrf" units="Hz" public_interface="in"/>
<variable name="ISAin" units="uA_per_mmsq" public_interface="in"/>
<variable name="start" units="ms"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>start</ci>
<piecewise>
<piece>
<ci>realtime</ci>
<apply>
<lt/>
<ci>ISAin</ci>
<cn cellml:units="uA_per_mmsq">0</cn>
</apply>
</piece>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beattime</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>realtime</ci>
<ci>start</ci>
</apply>
<apply>
<times/>
<apply>
<floor/>
<apply>
<divide/>
<apply>
<minus/>
<ci>realtime</ci>
<ci>start</ci>
</apply>
<ci>hrf</ci>
</apply>
</apply>
<ci>hrf</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
</math>
</component>
<component name="LAElastanceFunction">
<variable name="time" units="ms" public_interface="in"/>
<variable name="Esys" units="elastance" initial_value="0.365"/>
<variable name="Edia" units="elastance" initial_value="0.231"/>
<variable name="TsK" units="ms" initial_value="0.2"/>
<variable name="Ts" units="ms"/>
<variable name="hrf" units="Hz" public_interface="in"/>
<variable name="E_LA" units="elastance" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ts</ci>
<apply>
<times/>
<ci>TsK</ci>
<apply>
<root/>
<apply>
<divide/>
<ci>hrf</ci>
<cn cellml:units="Hz">1000</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E_LA</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>Edia</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>Esys</ci>
<ci>Edia</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<cos/>
<apply>
<divide/>
<apply>
<times/>
<pi/>
<ci>time</ci>
</apply>
<ci>Ts</ci>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>time</ci>
<cn cellml:units="ms">0</cn>
</apply>
<apply>
<leq/>
<ci>time</ci>
<ci>Ts</ci>
</apply>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>Edia</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>Esys</ci>
<ci>Edia</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<cos/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<pi/>
<apply>
<minus/>
<ci>time</ci>
<ci>Ts</ci>
</apply>
</apply>
<ci>Ts</ci>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>time</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1.5</cn>
<ci>Ts</ci>
</apply>
</apply>
<apply>
<geq/>
<ci>time</ci>
<ci>Ts</ci>
</apply>
</apply>
</piece>
<otherwise>
<ci>Edia</ci>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="LeftAtrium">
<variable name="time" units="ms" public_interface="in"/>
<variable name="E_LA" units="elastance" public_interface="in"/>
<variable name="P_PV" units="mmHg" public_interface="in"/>
<variable name="F_LV" units="flow" public_interface="in"/>
<variable name="P_LA_ext" units="mmHg" initial_value="0"/>
<variable name="V_LA" units="mL" initial_value="114.382943360704" public_interface="out"/>
<variable name="V_LA_0" units="mL" initial_value="100"/>
<variable name="P_LA" units="mmHg" public_interface="out"/>
<variable name="F_LA" units="flow" public_interface="out"/>
<variable name="R_LA" units="CVresistance" initial_value="0.01"/>
<variable name="conc_X_LA" units="concentration" public_interface="out"/>
<variable name="conc_X_PV" units="concentration" public_interface="in"/>
<variable name="sub_X_LA" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_LA</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_PV</ci>
<ci>F_LA</ci>
</apply>
<apply>
<times/>
<ci>conc_X_LA</ci>
<ci>F_LV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_LA</ci>
<apply>
<divide/>
<ci>sub_X_LA</ci>
<ci>V_LA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_LA</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>E_LA</ci>
<apply>
<minus/>
<ci>V_LA</ci>
<ci>V_LA_0</ci>
</apply>
</apply>
<ci>P_LA_ext</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_LA</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_PV</ci>
<ci>P_LA</ci>
</apply>
<ci>R_LA</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_LA</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_LA</ci>
<ci>F_LV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
</math>
</component>
<component name="LeftVentricle">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_AO" units="flow" public_interface="in"/>
<variable name="F_CO" units="flow" public_interface="in"/>
<variable name="P_LA" units="mmHg" public_interface="in"/>
<variable name="pLVPext" units="mmHg" initial_value="0"/>
<variable name="V_LV" units="mL" initial_value="46.5361989930178" public_interface="out"/>
<variable name="V_LV_0" units="mL" initial_value="30"/>
<variable name="P_LVin" units="mmHg" public_interface="in"/>
<variable name="F_LV" units="flow" public_interface="out"/>
<variable name="R_LV" units="CVresistance" initial_value="0.01"/>
<variable name="conc_X_LV" units="concentration" public_interface="out"/>
<variable name="conc_X_LA" units="concentration" public_interface="in"/>
<variable name="sub_X_LV" units="mL" initial_value="0"/>
<variable name="P_LV" units="mmHg"/>
<variable name="P_LA_ext" units="mmHg" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>P_LV</ci>
<apply>
<plus/>
<ci>P_LVin</ci>
<ci>P_LA_ext</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_LV</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_LA</ci>
<ci>F_LV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_LV</ci>
<apply>
<plus/>
<ci>F_AO</ci>
<ci>F_CO</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_LV</ci>
<apply>
<divide/>
<ci>sub_X_LV</ci>
<ci>V_LV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_LV</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_LA</ci>
<ci>P_LV</ci>
</apply>
<ci>R_LV</ci>
</apply>
<apply>
<gt/>
<ci>P_LA</ci>
<ci>P_LV</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="flow">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_LV</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>F_LV</ci>
<ci>F_AO</ci>
</apply>
<ci>F_CO</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
</math>
</component>
<component name="Aorta">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_CR" units="flow" public_interface="in"/>
<variable name="P_LV" units="mmHg" public_interface="in"/>
<variable name="F_AR" units="flow" public_interface="in"/>
<variable name="C_AO" units="capacitance" initial_value="1"/>
<variable name="L_AO" units="inductance" initial_value="5e-5"/>
<variable name="R_AO" units="CVresistance" initial_value="0.15"/>
<variable name="V_AO_0" units="mL" initial_value="100"/>
<variable name="V_AO" units="mL" initial_value="177.532128748274" public_interface="out"/>
<variable name="F_AOalways" units="flow" initial_value="-504.430041148081"/>
<variable name="F_AO" units="flow" public_interface="out"/>
<variable name="P_AO" units="mmHg" public_interface="out"/>
<variable name="conc_X_AO" units="concentration" public_interface="out"/>
<variable name="conc_X_LV" units="concentration" public_interface="in"/>
<variable name="sub_X_AO" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_AO</ci>
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<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_LV</ci>
<ci>F_AO</ci>
</apply>
<apply>
<times/>
<ci>conc_X_AO</ci>
<apply>
<plus/>
<ci>F_CR</ci>
<ci>F_AR</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_AO</ci>
<apply>
<divide/>
<ci>sub_X_AO</ci>
<ci>V_AO</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>F_AOalways</ci>
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<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>L_AO</ci>
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<apply>
<minus/>
<ci>P_LV</ci>
<ci>P_AO</ci>
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<apply>
<times/>
<apply>
<divide/>
<ci>R_AO</ci>
<ci>L_AO</ci>
</apply>
<ci>F_AOalways</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
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<apply>
<eq/>
<ci>F_AO</ci>
<piecewise>
<piece>
<ci>F_AOalways</ci>
<apply>
<gt/>
<ci>P_LV</ci>
<ci>P_AO</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="flow">0</cn>
</otherwise>
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<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_AO</ci>
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<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>F_AO</ci>
<ci>F_AR</ci>
</apply>
<ci>F_CR</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_AO</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_AO</ci>
</apply>
<apply>
<minus/>
<ci>V_AO</ci>
<ci>V_AO_0</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="CoronaryCirc">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_LV" units="mmHg" public_interface="in"/>
<variable name="P_RA" units="mmHg" public_interface="in"/>
<variable name="R_CO" units="CVresistance" initial_value="8"/>
<variable name="R_COV" units="CVresistance" initial_value="2.5"/>
<variable name="V_CO_0" units="mL" initial_value="15"/>
<variable name="C_CO" units="capacitance" initial_value="0.75"/>
<variable name="F_CO" units="flow" public_interface="out"/>
<variable name="F_COV" units="flow" public_interface="out"/>
<variable name="V_CO" units="mL" initial_value="24.930759461586" public_interface="out"/>
<variable name="P_CO" units="mmHg" public_interface="out"/>
<variable name="conc_X_CO" units="concentration" public_interface="out"/>
<variable name="conc_X_LV" units="concentration" public_interface="in"/>
<variable name="sub_X_CO" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_CO</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_LV</ci>
<ci>F_CO</ci>
</apply>
<apply>
<times/>
<ci>conc_X_CO</ci>
<ci>F_COV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_CO</ci>
<apply>
<divide/>
<ci>sub_X_CO</ci>
<ci>V_CO</ci>
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<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_CO</ci>
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<apply>
<divide/>
<apply>
<minus/>
<ci>F_CO</ci>
<ci>F_COV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_CO</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_CO</ci>
</apply>
<apply>
<minus/>
<ci>V_CO</ci>
<ci>V_CO_0</ci>
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</apply>
</apply>
<apply>
<eq/>
<ci>F_CO</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_LV</ci>
<ci>P_CO</ci>
</apply>
<ci>R_CO</ci>
</apply>
<apply>
<gt/>
<ci>P_LV</ci>
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</piece>
<otherwise>
<cn cellml:units="flow">0</cn>
</otherwise>
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<apply>
<eq/>
<ci>F_COV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_CO</ci>
<ci>P_RA</ci>
</apply>
<ci>R_COV</ci>
</apply>
</apply>
</math>
</component>
<component name="CarotidCirc">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AO" units="mmHg" public_interface="in"/>
<variable name="P_VC" units="mmHg" public_interface="in"/>
<variable name="R_CR" units="CVresistance" initial_value="11"/>
<variable name="R_CRV" units="CVresistance" initial_value="4"/>
<variable name="V_CR_0" units="mL" initial_value="30"/>
<variable name="C_CR" units="capacitance" initial_value="3"/>
<variable name="F_CR" units="flow" public_interface="out"/>
<variable name="F_CRV" units="flow" public_interface="out"/>
<variable name="V_CR" units="mL" initial_value="97.7894953935923" public_interface="out"/>
<variable name="P_CR" units="mmHg" public_interface="out"/>
<variable name="conc_X_CR" units="concentration" public_interface="out"/>
<variable name="conc_X_AO" units="concentration" public_interface="in"/>
<variable name="sub_X_CR" units="mL" initial_value="0"/>
<variable name="conc_X_CRtissue" units="concentration"/>
<variable name="D_CRtissue" units="flow" initial_value="1"/>
<variable name="V_CRtissue" units="mL" initial_value="1"/>
<variable name="sub_X_CRtissue" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>conc_X_CRtissue</ci>
<apply>
<divide/>
<ci>sub_X_CRtissue</ci>
<ci>V_CRtissue</ci>
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</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_CRtissue</ci>
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<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>conc_X_CR</ci>
<ci>conc_X_CRtissue</ci>
</apply>
<ci>D_CRtissue</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_CR</ci>
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<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AO</ci>
<ci>F_CR</ci>
</apply>
<apply>
<times/>
<ci>conc_X_CR</ci>
<ci>F_CRV</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<minus/>
<ci>conc_X_CR</ci>
<ci>conc_X_CRtissue</ci>
</apply>
<ci>D_CRtissue</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_CR</ci>
<apply>
<divide/>
<ci>sub_X_CR</ci>
<ci>V_CR</ci>
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</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<ci>V_CR</ci>
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<apply>
<divide/>
<apply>
<minus/>
<ci>F_CR</ci>
<ci>F_CRV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_CR</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_CR</ci>
</apply>
<apply>
<minus/>
<ci>V_CR</ci>
<ci>V_CR_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_CR</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AO</ci>
<ci>P_CR</ci>
</apply>
<ci>R_CR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_CRV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_CR</ci>
<ci>P_VC</ci>
</apply>
<ci>R_CRV</ci>
</apply>
</apply>
</math>
</component>
<component name="Arteries">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_AD" units="flow" public_interface="in"/>
<variable name="F_MU" units="flow" public_interface="in"/>
<variable name="F_GI" units="flow" public_interface="in"/>
<variable name="F_LI" units="flow" public_interface="in"/>
<variable name="F_KI" units="flow" public_interface="in"/>
<variable name="F_OT" units="flow" public_interface="in"/>
<variable name="F_SK" units="flow" public_interface="in"/>
<variable name="P_AO" units="mmHg" public_interface="in"/>
<variable name="R_AR" units="CVresistance" initial_value="1.5"/>
<variable name="C_AR" units="capacitance" initial_value="0.5"/>
<variable name="V_AR_0" units="mL" initial_value="370"/>
<variable name="V_AR" units="mL" initial_value="377.822162330503" public_interface="out"/>
<variable name="F_AR" units="flow" public_interface="out"/>
<variable name="P_AR" units="mmHg" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="out"/>
<variable name="conc_X_AO" units="concentration" public_interface="in"/>
<variable name="sub_X_AR" units="mL" initial_value="10"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_AR</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AO</ci>
<ci>F_AR</ci>
</apply>
<apply>
<times/>
<ci>conc_X_AR</ci>
<apply>
<plus/>
<ci>F_SK</ci>
<ci>F_AD</ci>
<ci>F_MU</ci>
<ci>F_GI</ci>
<ci>F_LI</ci>
<ci>F_KI</ci>
<ci>F_OT</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_AR</ci>
<apply>
<divide/>
<ci>sub_X_AR</ci>
<ci>V_AR</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_AR</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<ci>F_AR</ci>
<ci>F_AD</ci>
</apply>
<ci>F_MU</ci>
</apply>
<ci>F_GI</ci>
</apply>
<ci>F_LI</ci>
</apply>
<ci>F_KI</ci>
</apply>
<ci>F_OT</ci>
</apply>
<ci>F_SK</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_AR</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_AR</ci>
</apply>
<apply>
<minus/>
<ci>V_AR</ci>
<ci>V_AR_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_AR</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AO</ci>
<ci>P_AR</ci>
</apply>
<ci>R_AR</ci>
</apply>
</apply>
</math>
</component>
<component name="Adipose">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_VE" units="mmHg" public_interface="in"/>
<variable name="C_AD" units="capacitance" initial_value="30"/>
<variable name="R_AD" units="CVresistance" initial_value="1.2"/>
<variable name="R_ADV" units="CVresistance" initial_value="1"/>
<variable name="V_AD_0" units="mL" initial_value="225"/>
<variable name="V_AD" units="mL" initial_value="539.300411354071" public_interface="out"/>
<variable name="F_AD" units="flow" public_interface="out"/>
<variable name="F_ADV" units="flow" public_interface="out"/>
<variable name="P_AD" units="mmHg" public_interface="out"/>
<variable name="conc_X_AD" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="sub_X_AD" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_AD</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_AD</ci>
</apply>
<apply>
<times/>
<ci>conc_X_AD</ci>
<ci>F_ADV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_AD</ci>
<apply>
<divide/>
<ci>sub_X_AD</ci>
<ci>V_AD</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_AD</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_AD</ci>
<ci>F_ADV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_ADV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AD</ci>
<ci>P_VE</ci>
</apply>
<ci>R_ADV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_AD</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_AD</ci>
</apply>
<apply>
<minus/>
<ci>V_AD</ci>
<ci>V_AD_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_AD</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_AD</ci>
</apply>
<ci>R_AD</ci>
</apply>
</apply>
</math>
</component>
<component name="Muscle">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_VE" units="mmHg" public_interface="in"/>
<variable name="C_MU" units="capacitance" initial_value="60"/>
<variable name="R_MU" units="CVresistance" initial_value="0.9"/>
<variable name="R_MUV" units="CVresistance" initial_value="0.33"/>
<variable name="V_MU_0" units="mL" initial_value="1300"/>
<variable name="V_MU" units="mL" initial_value="1843.97747354682" public_interface="out"/>
<variable name="F_MU" units="flow" public_interface="out"/>
<variable name="F_MUV" units="flow" public_interface="out"/>
<variable name="P_MU" units="mmHg" public_interface="out"/>
<variable name="conc_X_MU" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="sub_X_MU" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_MU</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_MU</ci>
</apply>
<apply>
<times/>
<ci>conc_X_MU</ci>
<ci>F_MUV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_MU</ci>
<apply>
<divide/>
<ci>sub_X_MU</ci>
<ci>V_MU</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_MU</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_MU</ci>
<ci>F_MUV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_MUV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_MU</ci>
<ci>P_VE</ci>
</apply>
<ci>R_MUV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_MU</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_MU</ci>
</apply>
<apply>
<minus/>
<ci>V_MU</ci>
<ci>V_MU_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_MU</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_MU</ci>
</apply>
<ci>R_MU</ci>
</apply>
</apply>
</math>
</component>
<component name="GutIntestine">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_LI" units="mmHg" public_interface="in"/>
<variable name="C_GI" units="capacitance" initial_value="1.81"/>
<variable name="R_GI" units="CVresistance" initial_value="0.6"/>
<variable name="R_GIV" units="CVresistance" initial_value="0.15"/>
<variable name="V_GI_0" units="mL" initial_value="75"/>
<variable name="V_GI" units="mL" initial_value="95.4041027167494" public_interface="out"/>
<variable name="F_GI" units="flow" public_interface="out"/>
<variable name="F_GIV" units="flow" public_interface="out"/>
<variable name="P_GI" units="mmHg" public_interface="out"/>
<variable name="conc_X_GI" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="sub_X_GI" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_GI</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_GI</ci>
</apply>
<apply>
<times/>
<ci>conc_X_GI</ci>
<ci>F_GIV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_GI</ci>
<apply>
<divide/>
<ci>sub_X_GI</ci>
<ci>V_GI</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_GI</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_GI</ci>
<ci>F_GIV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_GIV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_GI</ci>
<ci>P_LI</ci>
</apply>
<ci>R_GIV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_GI</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_GI</ci>
</apply>
<apply>
<minus/>
<ci>V_GI</ci>
<ci>V_GI_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_GI</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_GI</ci>
</apply>
<ci>R_GI</ci>
</apply>
</apply>
</math>
</component>
<component name="Liver">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_VE" units="mmHg" public_interface="in"/>
<variable name="C_LI" units="capacitance" initial_value="1.81"/>
<variable name="R_LI" units="CVresistance" initial_value="0.9"/>
<variable name="R_LIV" units="CVresistance" initial_value="0.33"/>
<variable name="V_LI_0" units="mL" initial_value="75"/>
<variable name="V_LI" units="mL" initial_value="93.8781911234713" public_interface="out"/>
<variable name="F_LI" units="flow" public_interface="out"/>
<variable name="F_GIV" units="flow" public_interface="in"/>
<variable name="F_LIV" units="flow" public_interface="out"/>
<variable name="P_LI" units="mmHg" public_interface="out"/>
<variable name="conc_X_LI" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="conc_X_GI" units="concentration" public_interface="in"/>
<variable name="sub_X_LI" units="mL" initial_value="0"/>
<variable name="metabolism" units="flow" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_LI</ci>
</apply>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>conc_X_GI</ci>
<ci>F_GIV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_LI</ci>
</apply>
</apply>
<apply>
<times/>
<ci>conc_X_LI</ci>
<ci>F_LIV</ci>
</apply>
</apply>
<apply>
<times/>
<ci>conc_X_LI</ci>
<ci>metabolism</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_LI</ci>
<apply>
<divide/>
<ci>sub_X_LI</ci>
<ci>V_LI</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_LI</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>F_GIV</ci>
<ci>F_LI</ci>
</apply>
<ci>F_LIV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_LIV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_LI</ci>
<ci>P_VE</ci>
</apply>
<ci>R_LIV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_LI</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_LI</ci>
</apply>
<apply>
<minus/>
<ci>V_LI</ci>
<ci>V_LI_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_LI</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_LI</ci>
</apply>
<ci>R_LI</ci>
</apply>
</apply>
</math>
</component>
<component name="Kidney">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_VE" units="mmHg" public_interface="in"/>
<variable name="C_KI" units="capacitance" initial_value="0.5"/>
<variable name="R_KI" units="CVresistance" initial_value="0.8"/>
<variable name="V_KI_0" units="mL" initial_value="20"/>
<variable name="R_KIV" units="CVresistance" initial_value="0.2"/>
<variable name="V_KI" units="mL" initial_value="24.4012692216718" public_interface="out"/>
<variable name="F_KI" units="flow" public_interface="out"/>
<variable name="F_KIV" units="flow" public_interface="out"/>
<variable name="P_KI" units="mmHg" public_interface="out"/>
<variable name="conc_X_KI" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="sub_X_KI" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_KI</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_KI</ci>
</apply>
<apply>
<times/>
<ci>conc_X_KI</ci>
<ci>F_KIV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_KI</ci>
<apply>
<divide/>
<ci>sub_X_KI</ci>
<ci>V_KI</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_KI</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_KI</ci>
<ci>F_KIV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_KIV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_KI</ci>
<ci>P_VE</ci>
</apply>
<ci>R_KIV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_KI</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_KI</ci>
</apply>
<apply>
<minus/>
<ci>V_KI</ci>
<ci>V_KI_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_KI</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_KI</ci>
</apply>
<ci>R_KI</ci>
</apply>
</apply>
</math>
</component>
<component name="Skin">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_VE" units="mmHg" public_interface="in"/>
<variable name="C_SK" units="capacitance" initial_value="1.81"/>
<variable name="R_SK" units="CVresistance" initial_value="2.8"/>
<variable name="R_SKV" units="CVresistance" initial_value="0.7"/>
<variable name="V_SK_0" units="mL" initial_value="200"/>
<variable name="V_SK" units="mL" initial_value="215.48053377869" public_interface="out"/>
<variable name="F_SK" units="flow" public_interface="out"/>
<variable name="F_SKV" units="flow" public_interface="out"/>
<variable name="P_SK" units="mmHg" public_interface="out"/>
<variable name="conc_X_SK" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="sub_X_SK" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_SK</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_SK</ci>
</apply>
<apply>
<times/>
<ci>conc_X_SK</ci>
<ci>F_SKV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_SK</ci>
<apply>
<divide/>
<ci>sub_X_SK</ci>
<ci>V_SK</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_SK</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_SK</ci>
<ci>F_SKV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_SKV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_SK</ci>
<ci>P_VE</ci>
</apply>
<ci>R_SKV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_SK</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_SK</ci>
</apply>
<apply>
<minus/>
<ci>V_SK</ci>
<ci>V_SK_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_SK</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_SK</ci>
</apply>
<ci>R_SK</ci>
</apply>
</apply>
</math>
</component>
<component name="OtherTissue">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_AR" units="mmHg" public_interface="in"/>
<variable name="P_VE" units="mmHg" public_interface="in"/>
<variable name="C_OT" units="capacitance" initial_value="1.81"/>
<variable name="R_OT" units="CVresistance" initial_value="1"/>
<variable name="R_OTV" units="CVresistance" initial_value="0.33"/>
<variable name="V_OT_0" units="mL" initial_value="75"/>
<variable name="V_OT" units="mL" initial_value="91.1860503601169" public_interface="out"/>
<variable name="F_OT" units="flow" public_interface="out"/>
<variable name="F_OTV" units="flow" public_interface="out"/>
<variable name="P_OT" units="mmHg" public_interface="out"/>
<variable name="conc_X_OT" units="concentration" public_interface="out"/>
<variable name="conc_X_AR" units="concentration" public_interface="in"/>
<variable name="sub_X_OT" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_OT</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_AR</ci>
<ci>F_OT</ci>
</apply>
<apply>
<times/>
<ci>conc_X_OT</ci>
<ci>F_OTV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_OT</ci>
<apply>
<divide/>
<ci>sub_X_OT</ci>
<ci>V_OT</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_OT</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_OT</ci>
<ci>F_OTV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>F_OTV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_OT</ci>
<ci>P_VE</ci>
</apply>
<ci>R_OTV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_OT</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_OT</ci>
</apply>
<apply>
<minus/>
<ci>V_OT</ci>
<ci>V_OT_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_OT</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_AR</ci>
<ci>P_OT</ci>
</apply>
<ci>R_OT</ci>
</apply>
</apply>
</math>
</component>
<component name="Veins">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_ADV" units="flow" public_interface="in"/>
<variable name="F_MUV" units="flow" public_interface="in"/>
<variable name="F_LIV" units="flow" public_interface="in"/>
<variable name="F_KIV" units="flow" public_interface="in"/>
<variable name="F_OTV" units="flow" public_interface="in"/>
<variable name="F_SKV" units="flow" public_interface="in"/>
<variable name="P_VC" units="mmHg" public_interface="in"/>
<variable name="R_VEV" units="CVresistance" initial_value="0.0223"/>
<variable name="V_VE" units="mL" initial_value="457.346412168043" public_interface="out"/>
<variable name="C_VE" units="capacitance" initial_value="8"/>
<variable name="V_VE_0" units="mL" initial_value="400"/>
<variable name="F_VE" units="flow" public_interface="out"/>
<variable name="F_VEV" units="flow" public_interface="out"/>
<variable name="P_VE" units="mmHg" public_interface="out"/>
<variable name="conc_X_VE" units="concentration" public_interface="out"/>
<variable name="conc_X_AD" units="concentration" public_interface="in"/>
<variable name="conc_X_MU" units="concentration" public_interface="in"/>
<variable name="conc_X_LI" units="concentration" public_interface="in"/>
<variable name="conc_X_KI" units="concentration" public_interface="in"/>
<variable name="conc_X_SK" units="concentration" public_interface="in"/>
<variable name="conc_X_OT" units="concentration" public_interface="in"/>
<variable name="sub_X_VE" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_VE</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>conc_X_SK</ci>
<ci>F_SKV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_AD</ci>
<ci>F_ADV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_MU</ci>
<ci>F_MUV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_LI</ci>
<ci>F_LIV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_KI</ci>
<ci>F_KIV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_OT</ci>
<ci>F_OTV</ci>
</apply>
</apply>
<apply>
<times/>
<ci>conc_X_VE</ci>
<ci>F_VEV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_VE</ci>
<apply>
<divide/>
<ci>sub_X_VE</ci>
<ci>V_VE</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_VE</ci>
<apply>
<plus/>
<ci>F_SKV</ci>
<ci>F_ADV</ci>
<ci>F_MUV</ci>
<ci>F_LIV</ci>
<ci>F_KIV</ci>
<ci>F_OTV</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_VE</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_VE</ci>
<ci>F_VEV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_VE</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_VE</ci>
</apply>
<apply>
<minus/>
<ci>V_VE</ci>
<ci>V_VE_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_VEV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_VE</ci>
<ci>P_VC</ci>
</apply>
<ci>R_VEV</ci>
</apply>
</apply>
</math>
</component>
<component name="VenaCava">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_VEV" units="flow" public_interface="in"/>
<variable name="P_RA" units="mmHg" public_interface="in"/>
<variable name="F_CRV" units="flow" public_interface="in"/>
<variable name="R_VCV" units="CVresistance" initial_value="0.00267"/>
<variable name="V_VC" units="mL" initial_value="629.887803989648" public_interface="out"/>
<variable name="V_VC_0" units="mL" initial_value="500"/>
<variable name="C_VC" units="capacitance" initial_value="20"/>
<variable name="F_VC" units="flow" public_interface="out"/>
<variable name="F_VCV" units="flow" public_interface="out"/>
<variable name="P_VC" units="mmHg" public_interface="out"/>
<variable name="conc_X_VC" units="concentration" public_interface="out"/>
<variable name="conc_X_VE" units="concentration" public_interface="in"/>
<variable name="conc_X_CR" units="concentration" public_interface="in"/>
<variable name="sub_X_VC" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_VC</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>conc_X_VE</ci>
<ci>F_VEV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_CR</ci>
<ci>F_CRV</ci>
</apply>
</apply>
<apply>
<times/>
<ci>conc_X_VC</ci>
<ci>F_VCV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_VC</ci>
<apply>
<divide/>
<ci>sub_X_VC</ci>
<ci>V_VC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_VC</ci>
<apply>
<plus/>
<ci>F_CRV</ci>
<ci>F_VEV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_VCV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_VC</ci>
<ci>P_RA</ci>
</apply>
<ci>R_VCV</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_VC</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_VC</ci>
<ci>F_VCV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_VC</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_VC</ci>
</apply>
<apply>
<minus/>
<ci>V_VC</ci>
<ci>V_VC_0</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="RATiming">
<variable name="realtime" units="ms" public_interface="in"/>
<variable name="HR" units="ratepm" public_interface="in"/>
<variable name="beattime" units="ms" public_interface="out"/>
<variable name="hrf" units="Hz" public_interface="in"/>
<variable name="ISAin" units="uA_per_mmsq" public_interface="in"/>
<variable name="start" units="ms"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>start</ci>
<piecewise>
<piece>
<ci>realtime</ci>
<apply>
<lt/>
<ci>ISAin</ci>
<cn cellml:units="uA_per_mmsq">0</cn>
</apply>
</piece>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beattime</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>realtime</ci>
<ci>start</ci>
</apply>
<apply>
<times/>
<apply>
<floor/>
<apply>
<divide/>
<apply>
<minus/>
<ci>realtime</ci>
<ci>start</ci>
</apply>
<ci>hrf</ci>
</apply>
</apply>
<ci>hrf</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
</math>
</component>
<component name="RAElastanceFunction">
<variable name="time" units="ms" public_interface="in"/>
<variable name="Esys" units="elastance" initial_value="0.11"/>
<variable name="Edia" units="elastance" initial_value="0.099"/>
<variable name="TsK" units="second" initial_value="0.2"/>
<variable name="Ts" units="second"/>
<variable name="hrf" units="Hz" public_interface="in"/>
<variable name="E_RA" units="elastance" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ts</ci>
<apply>
<times/>
<ci>TsK</ci>
<apply>
<root/>
<apply>
<divide/>
<ci>hrf</ci>
<cn cellml:units="Hz">1000</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>E_RA</ci>
<piecewise>
<piece>
<apply>
<plus/>
<ci>Edia</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>Esys</ci>
<ci>Edia</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<cos/>
<apply>
<divide/>
<apply>
<times/>
<pi/>
<ci>time</ci>
</apply>
<ci>Ts</ci>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>time</ci>
<cn cellml:units="second">0</cn>
</apply>
<apply>
<leq/>
<ci>time</ci>
<ci>Ts</ci>
</apply>
</apply>
</piece>
<piece>
<apply>
<plus/>
<ci>Edia</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>Esys</ci>
<ci>Edia</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<cos/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<pi/>
<apply>
<minus/>
<ci>time</ci>
<ci>Ts</ci>
</apply>
</apply>
<ci>Ts</ci>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<and/>
<apply>
<lt/>
<ci>time</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">1.5</cn>
<ci>Ts</ci>
</apply>
</apply>
<apply>
<geq/>
<ci>time</ci>
<ci>Ts</ci>
</apply>
</apply>
</piece>
<otherwise>
<ci>Edia</ci>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="RightAtrium">
<variable name="time" units="ms" public_interface="in"/>
<variable name="E_RA" units="elastance" public_interface="in"/>
<variable name="F_RV" units="flow" public_interface="in"/>
<variable name="F_VCV" units="flow" public_interface="in"/>
<variable name="F_COV" units="flow" public_interface="in"/>
<variable name="P_RA_ext" units="mmHg" initial_value="0"/>
<variable name="V_RA" units="mL" initial_value="78.8296697240886" public_interface="out"/>
<variable name="V_RA_0" units="mL" initial_value="15"/>
<variable name="P_RA" units="mmHg" public_interface="out"/>
<variable name="F_RA" units="flow" public_interface="out"/>
<variable name="conc_X_RA" units="concentration" public_interface="out"/>
<variable name="conc_X_VC" units="concentration" public_interface="in"/>
<variable name="conc_X_CO" units="concentration" public_interface="in"/>
<variable name="sub_X_RA" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_RA</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>conc_X_VC</ci>
<ci>F_VCV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_CO</ci>
<ci>F_COV</ci>
</apply>
</apply>
<apply>
<times/>
<ci>conc_X_RA</ci>
<ci>F_RV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_RA</ci>
<apply>
<divide/>
<ci>sub_X_RA</ci>
<ci>V_RA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_RA</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>E_RA</ci>
<apply>
<minus/>
<ci>V_RA</ci>
<ci>V_RA_0</ci>
</apply>
</apply>
<ci>P_RA_ext</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_RA</ci>
<apply>
<plus/>
<ci>F_VCV</ci>
<ci>F_COV</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_RA</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_RA</ci>
<ci>F_RV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
</math>
</component>
<component name="RightVentricle">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_RA" units="mmHg" public_interface="in"/>
<variable name="F_PA" units="flow" public_interface="in"/>
<variable name="P_RV_ext" units="mmHg" initial_value="0"/>
<variable name="V_RV" units="mL" initial_value="120.130190319487" public_interface="out"/>
<variable name="V_RV_0" units="mL" initial_value="25"/>
<variable name="P_RV" units="mmHg" public_interface="out"/>
<variable name="F_RV" units="flow" public_interface="out"/>
<variable name="R_RV" units="CVresistance" initial_value="0.02"/>
<variable name="conc_X_RV" units="concentration" public_interface="out"/>
<variable name="conc_X_RA" units="concentration" public_interface="in"/>
<variable name="sub_X_RV" units="mL" initial_value="0"/>
<variable name="EmaxLV" units="elastance" initial_value="3.6"/>
<variable name="EmaxRV" units="elastance" initial_value="1.75"/>
<variable name="kelv" units="per_mL" initial_value="0.014"/>
<variable name="kerv" units="per_mL" initial_value="0.011"/>
<variable name="P0lv" units="mmHg" initial_value="1.5"/>
<variable name="P0rv" units="mmHg" initial_value="1.5"/>
<variable name="lva" units="mmHg"/>
<variable name="rva" units="mmHg"/>
<variable name="lvb" units="mmHg"/>
<variable name="rvb" units="mmHg"/>
<variable name="P_LV" units="mmHg" public_interface="in"/>
<variable name="V_LV" units="mL" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>lva</ci>
<apply>
<times/>
<ci>EmaxLV</ci>
<cn cellml:units="mL">10</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>rva</ci>
<apply>
<times/>
<ci>EmaxRV</ci>
<cn cellml:units="mL">10</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>lvb</ci>
<apply>
<times/>
<ci>P0lv</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<ci>kelv</ci>
<ci>V_LV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>rvb</ci>
<apply>
<times/>
<ci>P0rv</ci>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<ci>kerv</ci>
<ci>V_RV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>P_RV</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>P_LV</ci>
<ci>lvb</ci>
</apply>
<ci>rva</ci>
</apply>
<apply>
<minus/>
<ci>lva</ci>
<ci>lvb</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>lva</ci>
<ci>P_LV</ci>
</apply>
<ci>rvb</ci>
</apply>
<apply>
<minus/>
<ci>lva</ci>
<ci>lvb</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_RV</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_RA</ci>
<ci>F_RV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_RV</ci>
<ci>F_PA</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_RV</ci>
<apply>
<divide/>
<ci>sub_X_RV</ci>
<ci>V_RV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_RV</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_RA</ci>
<ci>P_RV</ci>
</apply>
<ci>R_RV</ci>
</apply>
<apply>
<gt/>
<ci>P_RA</ci>
<ci>P_RV</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="flow">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_RV</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_RV</ci>
<ci>F_PA</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
</math>
</component>
<component name="PulmonaryArtery">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_Pa" units="flow" public_interface="in"/>
<variable name="P_RV" units="mmHg" public_interface="in"/>
<variable name="R_PA" units="CVresistance" initial_value="0.2"/>
<variable name="C_PA" units="capacitance" initial_value="1"/>
<variable name="V_PA_0" units="mL" initial_value="50"/>
<variable name="F_PA" units="flow" public_interface="out"/>
<variable name="V_PA" units="mL" initial_value="56.0809022882693" public_interface="out"/>
<variable name="P_PA" units="mmHg" public_interface="out"/>
<variable name="conc_X_PA" units="concentration" public_interface="out"/>
<variable name="conc_X_RV" units="concentration" public_interface="in"/>
<variable name="sub_X_PA" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_PA</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_RV</ci>
<ci>F_PA</ci>
</apply>
<apply>
<times/>
<ci>conc_X_PA</ci>
<ci>F_Pa</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_PA</ci>
<apply>
<divide/>
<ci>sub_X_PA</ci>
<ci>V_PA</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_PA</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_RV</ci>
<ci>P_PA</ci>
</apply>
<ci>R_PA</ci>
</apply>
<apply>
<gt/>
<ci>P_RV</ci>
<ci>P_PA</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="flow">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_PA</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_PA</ci>
<ci>F_Pa</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_PA</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_PA</ci>
</apply>
<apply>
<minus/>
<ci>V_PA</ci>
<ci>V_PA_0</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="PulmonaryArteries">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_PA" units="mmHg" public_interface="in"/>
<variable name="F_PC" units="flow" public_interface="in"/>
<variable name="F_SH" units="flow" public_interface="in"/>
<variable name="V_Pa" units="mL" initial_value="37.3085495287075" public_interface="out"/>
<variable name="C_Pa" units="capacitance" initial_value="1.481"/>
<variable name="R_Pa" units="CVresistance" initial_value="0.053"/>
<variable name="V_Pa_0" units="mL" initial_value="30"/>
<variable name="F_Pa" units="flow" public_interface="out"/>
<variable name="P_Pa" units="mmHg" public_interface="out"/>
<variable name="conc_X_Pa" units="concentration" public_interface="out"/>
<variable name="conc_X_PA" units="concentration" public_interface="in"/>
<variable name="sub_X_Pa" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_Pa</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_PA</ci>
<ci>F_Pa</ci>
</apply>
<apply>
<times/>
<ci>conc_X_Pa</ci>
<apply>
<plus/>
<ci>F_PC</ci>
<ci>F_SH</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_Pa</ci>
<apply>
<divide/>
<ci>sub_X_Pa</ci>
<ci>V_Pa</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_Pa</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>F_Pa</ci>
<ci>F_PC</ci>
</apply>
<ci>F_SH</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_Pa</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_Pa</ci>
</apply>
<apply>
<minus/>
<ci>V_Pa</ci>
<ci>V_Pa_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_Pa</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_PA</ci>
<ci>P_Pa</ci>
</apply>
<ci>R_Pa</ci>
</apply>
</apply>
</math>
</component>
<component name="Shunt">
<variable name="time" units="ms" public_interface="in"/>
<variable name="R_SH" units="CVresistance" initial_value="50000000000"/>
<variable name="F_SH" units="flow" public_interface="out"/>
<variable name="P_Pa" units="mmHg" public_interface="in"/>
<variable name="P_PC" units="mmHg" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>F_SH</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_Pa</ci>
<ci>P_PC</ci>
</apply>
<ci>R_SH</ci>
</apply>
</apply>
</math>
</component>
<component name="PulmonaryCapillaries">
<variable name="time" units="ms" public_interface="in"/>
<variable name="P_Pa" units="mmHg" public_interface="in"/>
<variable name="P_PV" units="mmHg" public_interface="in"/>
<variable name="C_PC" units="capacitance" initial_value="1.778"/>
<variable name="R_PC" units="CVresistance" initial_value="0.0179"/>
<variable name="R_PCV" units="CVresistance" initial_value="0.0079"/>
<variable name="V_PC_0" units="mL" initial_value="53"/>
<variable name="V_PC" units="mL" initial_value="60.6769769228579" public_interface="out"/>
<variable name="F_PC" units="flow" public_interface="out"/>
<variable name="F_PCV" units="flow" public_interface="out"/>
<variable name="P_PC" units="mmHg" public_interface="out"/>
<variable name="conc_X_PC" units="concentration" public_interface="out"/>
<variable name="conc_X_Pa" units="concentration" public_interface="in"/>
<variable name="sub_X_PC" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_PC</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>conc_X_Pa</ci>
<ci>F_PC</ci>
</apply>
<apply>
<times/>
<ci>conc_X_PC</ci>
<ci>F_PCV</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_PC</ci>
<apply>
<divide/>
<ci>sub_X_PC</ci>
<ci>V_PC</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_PC</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_PC</ci>
<ci>F_PCV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_PC</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_PC</ci>
</apply>
<apply>
<minus/>
<ci>V_PC</ci>
<ci>V_PC_0</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>F_PC</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_Pa</ci>
<ci>P_PC</ci>
</apply>
<ci>R_PC</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_PCV</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>P_PC</ci>
<ci>P_PV</ci>
</apply>
<ci>R_PCV</ci>
</apply>
</apply>
</math>
</component>
<component name="PulmonaryVein">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_PCV" units="flow" public_interface="in"/>
<variable name="F_SH" units="flow" public_interface="in"/>
<variable name="F_LA" units="flow" public_interface="in"/>
<variable name="C_PV" units="capacitance" initial_value="2"/>
<variable name="V_PV_0" units="mL" initial_value="70"/>
<variable name="V_PV" units="mL" initial_value="77.9150700144446" public_interface="out"/>
<variable name="F_PV" units="flow" public_interface="out"/>
<variable name="P_PV" units="mmHg" public_interface="out"/>
<variable name="conc_X_PV" units="concentration" public_interface="out"/>
<variable name="conc_X_PC" units="concentration" public_interface="in"/>
<variable name="conc_X_Pa" units="concentration" public_interface="in"/>
<variable name="sub_X_PV" units="mL" initial_value="0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>sub_X_PV</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<times/>
<ci>conc_X_PC</ci>
<ci>F_PCV</ci>
</apply>
<apply>
<times/>
<ci>conc_X_Pa</ci>
<ci>F_SH</ci>
</apply>
</apply>
<apply>
<times/>
<ci>conc_X_PV</ci>
<ci>F_LA</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>conc_X_PV</ci>
<apply>
<divide/>
<ci>sub_X_PV</ci>
<ci>V_PV</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>F_PV</ci>
<apply>
<plus/>
<ci>F_PCV</ci>
<ci>F_SH</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V_PV</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>F_PV</ci>
<ci>F_LA</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>P_PV</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<ci>C_PV</ci>
</apply>
<apply>
<minus/>
<ci>V_PV</ci>
<ci>V_PV_0</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="additional_currents">
<variable name="IK_additional" units="uA_per_mmsq" public_interface="out"/>
<variable name="ICa_additional" units="uA_per_mmsq" public_interface="out"/>
<variable name="INa_additional" units="uA_per_mmsq" initial_value="0" public_interface="out"/>
<variable name="JCaSR_additional" units="mM_per_ms" initial_value="0" public_interface="out"/>
<variable name="Istim" units="uA_per_mmsq" initial_value="0" public_interface="out"/>
<variable name="Cai" units="uA_per_mmsq" public_interface="in"/>
<variable name="topOUt" units="uA_per_mmsq" initial_value="-0.00063"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICa_additional</ci>
<apply>
<minus/>
<ci>topOUt</ci>
<ci>Cai</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>IK_additional</ci>
<apply>
<minus/>
<ci>Istim</ci>
</apply>
</apply>
</math>
</component>
<component name="default_parameters">
<variable name="Am" units="per_mm" initial_value="200" public_interface="out"/>
<variable name="Cm" units="uF_per_mmsq" initial_value="0.01" public_interface="out"/>
<variable name="Capacitance" units="uF_per_mmsq" initial_value="0.00185" public_interface="out"/>
<variable name="temperature" units="K" initial_value="310" public_interface="out"/>
<variable name="vC" units="dimensionless" initial_value="0.49" public_interface="out"/>
<variable name="vSR" units="dimensionless" initial_value="0.1" public_interface="out"/>
<variable name="g_Na" units="mS_per_mmsq" initial_value="0.14838" public_interface="out"/>
<variable name="g_K1" units="mS_per_mmsq" initial_value="0.05405" public_interface="out"/>
<variable name="g_to" units="mS_per_mmsq" initial_value="0.00294" public_interface="out"/>
<variable name="g_Kr" units="mS_per_mmsq" initial_value="0.00096" public_interface="out"/>
<variable name="g_Ks" units="mS_per_mmsq" initial_value="0.00245" public_interface="out"/>
<variable name="g_pK" units="mS_per_mmsq" initial_value="0.000146" public_interface="out"/>
<variable name="g_bNa" units="mS_per_mmsq" initial_value="2.9e-6" public_interface="out"/>
<variable name="g_bCa" units="mS_per_mmsq" initial_value="5.92e-6" public_interface="out"/>
<variable name="p_KNa" units="dimensionless" initial_value="0.03" public_interface="out"/>
<variable name="P_NaK" units="uA_per_mmsq" initial_value="0.01362" public_interface="out"/>
<variable name="K_mNa" units="mM" initial_value="40" public_interface="out"/>
<variable name="K_mK" units="mM" initial_value="1" public_interface="out"/>
<variable name="g_CaL" units="mm_per_ms" initial_value="1.75e-6" public_interface="out"/>
<variable name="Bufc" units="mM" initial_value="0.14" public_interface="out"/>
<variable name="Kbufc" units="mM" initial_value="0.001" public_interface="out"/>
<variable name="Bufsr" units="mM" initial_value="10" public_interface="out"/>
<variable name="Kbufsr" units="mM" initial_value="0.3" public_interface="out"/>
<variable name="Nao" units="mM" initial_value="140" public_interface="out"/>
<variable name="Ko" units="mM" initial_value="5.4" public_interface="out"/>
<variable name="Cao" units="mM" initial_value="2" public_interface="out"/>
<variable name="V_leak" units="per_ms" initial_value="8e-5" public_interface="out"/>
<variable name="K_up" units="mM" initial_value="0.00025" public_interface="out"/>
<variable name="Vmax_up" units="mM_per_ms" initial_value="0.000425" public_interface="out"/>
<variable name="a_rel" units="mM_per_ms" initial_value="0.016464" public_interface="out"/>
<variable name="b_rel" units="mM" initial_value="0.25" public_interface="out"/>
<variable name="c_rel" units="mM_per_ms" initial_value="0.008232" public_interface="out"/>
<variable name="tau_g" units="ms" initial_value="2" public_interface="out"/>
<variable name="g_pCa" units="uA_per_mmsq" initial_value="0.00825" public_interface="out"/>
<variable name="K_pCa" units="mM" initial_value="0.0005" public_interface="out"/>
<variable name="k_NaCa" units="uA_per_mmsq" initial_value="10" public_interface="out"/>
<variable name="K_mNai" units="mM" initial_value="87.5" public_interface="out"/>
<variable name="K_mCa" units="mM" initial_value="1.38" public_interface="out"/>
<variable name="k_sat" units="dimensionless" initial_value="0.1" public_interface="out"/>
<variable name="gamma" units="dimensionless" initial_value="0.35" public_interface="out"/>
<variable name="alpha" units="dimensionless" initial_value="2.5" public_interface="out"/>
</component>
<component name="default_initial_conditions">
<variable name="V_initial" units="mV" initial_value="-86.2" public_interface="out"/>
<variable name="m_initial" units="dimensionless" initial_value="0" public_interface="out"/>
<variable name="h_initial" units="dimensionless" initial_value="0.75" public_interface="out"/>
<variable name="j_initial" units="dimensionless" initial_value="0.75" public_interface="out"/>
<variable name="s_initial" units="dimensionless" initial_value="1" public_interface="out"/>
<variable name="r_initial" units="dimensionless" initial_value="0" public_interface="out"/>
<variable name="Xr1_initial" units="dimensionless" initial_value="0" public_interface="out"/>
<variable name="Xr2_initial" units="dimensionless" initial_value="1" public_interface="out"/>
<variable name="Xs_initial" units="dimensionless" initial_value="0" public_interface="out"/>
<variable name="d_initial" units="dimensionless" initial_value="0" public_interface="out"/>
<variable name="f_initial" units="dimensionless" initial_value="1" public_interface="out"/>
<variable name="fCa_initial" units="dimensionless" initial_value="1" public_interface="out"/>
<variable name="g_initial" units="dimensionless" initial_value="1" public_interface="out"/>
<variable name="Nai_initial" units="mM" initial_value="11.6" public_interface="out"/>
<variable name="Ki_initial" units="mM" initial_value="138.3" public_interface="out"/>
<variable name="Cai_total_initial" units="mM" initial_value="0.0064" public_interface="out"/>
<variable name="CaSR_total_initial" units="mM" initial_value="4.2" public_interface="out"/>
</component>
<component name="membrane_potential">
<variable name="V" units="mV" initial_value="-64.7550201989744" public_interface="out"/>
<variable name="V_initial" units="mV" public_interface="in"/>
<variable name="Cm" units="uF_per_mmsq" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="Itotal" units="uA_per_mmsq" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Itotal</ci>
</apply>
<ci>Cm</ci>
</apply>
</apply>
</math>
</component>
<component name="total_membrane_current">
<variable name="Itotal" units="uA_per_mmsq" public_interface="out" private_interface="out"/>
<variable name="ICa_additional" units="uA_per_mmsq" public_interface="in"/>
<variable name="INa_additional" units="uA_per_mmsq" public_interface="in"/>
<variable name="IK_additional" units="uA_per_mmsq" public_interface="in"/>
<variable name="INa" units="uA_per_mmsq" public_interface="in"/>
<variable name="IK1" units="uA_per_mmsq" public_interface="in"/>
<variable name="Ito" units="uA_per_mmsq" public_interface="in"/>
<variable name="IKr" units="uA_per_mmsq" public_interface="in"/>
<variable name="IKs" units="uA_per_mmsq" public_interface="in"/>
<variable name="ICaL" units="uA_per_mmsq" public_interface="in"/>
<variable name="INaCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="INaK" units="uA_per_mmsq" public_interface="in"/>
<variable name="IpCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="IpK" units="uA_per_mmsq" public_interface="in"/>
<variable name="IbCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="IbNa" units="uA_per_mmsq" public_interface="in"/>
<variable name="ISAstim" units="uA_per_mmsq" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Itotal</ci>
<apply>
<plus/>
<ci>ISAstim</ci>
<ci>ICa_additional</ci>
<ci>INa_additional</ci>
<ci>IK_additional</ci>
<ci>INa</ci>
<ci>IK1</ci>
<ci>Ito</ci>
<ci>IKr</ci>
<ci>IKs</ci>
<ci>ICaL</ci>
<ci>INaCa</ci>
<ci>INaK</ci>
<ci>IbNa</ci>
<ci>IbCa</ci>
<ci>IpCa</ci>
<ci>IpK</ci>
</apply>
</apply>
</math>
</component>
<component name="K_flux">
<variable name="K_flux" units="mM_per_ms" public_interface="out" private_interface="out"/>
<variable name="vC" units="dimensionless" public_interface="in"/>
<variable name="Am" units="per_mm" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="IK_additional" units="uA_per_mmsq" public_interface="in"/>
<variable name="IK1" units="uA_per_mmsq" public_interface="in"/>
<variable name="Ito" units="uA_per_mmsq" public_interface="in"/>
<variable name="IKr" units="uA_per_mmsq" public_interface="in"/>
<variable name="IKs" units="uA_per_mmsq" public_interface="in"/>
<variable name="INaK" units="uA_per_mmsq" public_interface="in"/>
<variable name="IpK" units="uA_per_mmsq" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>K_flux</ci>
<apply>
<times/>
<apply>
<divide/>
<ci>Am</ci>
<apply>
<times/>
<ci>vC</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<ci>IK_additional</ci>
<ci>IK1</ci>
<ci>Ito</ci>
<ci>IKr</ci>
<ci>IKs</ci>
<ci>IpK</ci>
</apply>
<apply>
<times/>
<ci>INaK</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Na_flux">
<variable name="Na_flux" units="mM_per_ms" public_interface="out" private_interface="out"/>
<variable name="vC" units="dimensionless" public_interface="in"/>
<variable name="Am" units="per_mm" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="INa_additional" units="uA_per_mmsq" public_interface="in"/>
<variable name="INa" units="uA_per_mmsq" public_interface="in"/>
<variable name="IbNa" units="uA_per_mmsq" public_interface="in"/>
<variable name="INaK" units="uA_per_mmsq" public_interface="in"/>
<variable name="INaCa" units="uA_per_mmsq" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Na_flux</ci>
<apply>
<times/>
<apply>
<divide/>
<ci>Am</ci>
<apply>
<times/>
<ci>vC</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>INa</ci>
<ci>INa_additional</ci>
<ci>IbNa</ci>
<apply>
<times/>
<ci>INaK</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<times/>
<ci>INaCa</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Ca_flux">
<variable name="Ca_flux" units="mM_per_ms" public_interface="out" private_interface="out"/>
<variable name="vC" units="dimensionless" public_interface="in"/>
<variable name="Am" units="per_mm" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="ICa_additional" units="uA_per_mmsq" public_interface="in"/>
<variable name="ICaL" units="uA_per_mmsq" public_interface="in"/>
<variable name="IbCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="IpCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="INaCa" units="uA_per_mmsq" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ca_flux</ci>
<apply>
<times/>
<apply>
<divide/>
<ci>Am</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>vC</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>INaCa</ci>
</apply>
<apply>
<plus/>
<ci>ICa_additional</ci>
<ci>ICaL</ci>
<ci>IbCa</ci>
<ci>IpCa</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Ca_SR_flux">
<variable name="Ca_SR_flux" units="mM_per_ms" public_interface="out" private_interface="out"/>
<variable name="Jleak" units="mM_per_ms" public_interface="in"/>
<variable name="Jup" units="mM_per_ms" public_interface="in"/>
<variable name="Jrel" units="mM_per_ms" public_interface="in"/>
<variable name="JCaSR_additional" units="mM_per_ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ca_SR_flux</ci>
<apply>
<minus/>
<apply>
<plus/>
<ci>Jleak</ci>
<ci>Jrel</ci>
<ci>JCaSR_additional</ci>
</apply>
<ci>Jup</ci>
</apply>
</apply>
</math>
</component>
<component name="INa">
<variable name="INa" units="uA_per_mmsq" public_interface="out"/>
<variable name="time" units="ms" public_interface="in" private_interface="out"/>
<variable name="V" units="mV" public_interface="in" private_interface="out"/>
<variable name="E_Na" units="mV" public_interface="in"/>
<variable name="g_Na" units="mS_per_mmsq" public_interface="in"/>
<variable name="m" units="dimensionless" public_interface="in"/>
<variable name="h" units="dimensionless" public_interface="in"/>
<variable name="j" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INa</ci>
<apply>
<times/>
<ci>g_Na</ci>
<apply>
<power/>
<ci>m</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>h</ci>
<ci>j</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IK1">
<variable name="IK1" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_K1" units="mS_per_mmsq" public_interface="in"/>
<variable name="V" units="mV" public_interface="in" private_interface="out"/>
<variable name="Ko" units="mM" public_interface="in"/>
<variable name="E_K" units="mV" public_interface="in"/>
<variable name="K1_infinity" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IK1</ci>
<apply>
<times/>
<ci>g_K1</ci>
<apply>
<root/>
<apply>
<divide/>
<ci>Ko</ci>
<cn cellml:units="mM">5.4</cn>
</apply>
</apply>
<ci>K1_infinity</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Ito">
<variable name="Ito" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_to" units="mS_per_mmsq" public_interface="in"/>
<variable name="E_K" units="mV" public_interface="in"/>
<variable name="V" units="mV" public_interface="in" private_interface="out"/>
<variable name="time" units="ms" public_interface="in" private_interface="out"/>
<variable name="s" units="dimensionless" public_interface="in"/>
<variable name="r" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ito</ci>
<apply>
<times/>
<ci>g_to</ci>
<ci>r</ci>
<ci>s</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IKr">
<variable name="IKr" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_Kr" units="mS_per_mmsq" public_interface="in"/>
<variable name="time" units="ms" public_interface="in" private_interface="out"/>
<variable name="V" units="mV" public_interface="in" private_interface="out"/>
<variable name="E_K" units="mV" public_interface="in"/>
<variable name="Ko" units="mM" public_interface="in"/>
<variable name="Xr1" units="dimensionless" public_interface="in"/>
<variable name="Xr2" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IKr</ci>
<apply>
<times/>
<ci>g_Kr</ci>
<apply>
<root/>
<apply>
<divide/>
<ci>Ko</ci>
<cn cellml:units="mM">5.4</cn>
</apply>
</apply>
<ci>Xr1</ci>
<ci>Xr2</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IKs">
<variable name="IKs" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_Ks" units="mS_per_mmsq" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="E_Ks" units="mV" public_interface="in"/>
<variable name="Xs" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IKs</ci>
<apply>
<times/>
<ci>g_Ks</ci>
<apply>
<power/>
<ci>Xs</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ks</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="INaK">
<variable name="INaK" units="uA_per_mmsq" public_interface="out"/>
<variable name="P_NaK" units="uA_per_mmsq" public_interface="in"/>
<variable name="K_mNa" units="mM" public_interface="in"/>
<variable name="K_mK" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="R" units="gas_constant" public_interface="in"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="Nai" units="mM" public_interface="in"/>
<variable name="Ko" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INaK</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>P_NaK</ci>
<ci>Ko</ci>
<ci>Nai</ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci>Ko</ci>
<ci>K_mK</ci>
</apply>
<apply>
<plus/>
<ci>Nai</ci>
<ci>K_mNa</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.1245</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">0.1</cn>
</apply>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0353</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IpK">
<variable name="IpK" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_pK" units="mS_per_mmsq" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="E_K" units="mV" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IpK</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>g_pK</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="mV">25</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">5.98</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IbNa">
<variable name="IbNa" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_bNa" units="mS_per_mmsq" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="E_Na" units="mV" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IbNa</ci>
<apply>
<times/>
<ci>g_bNa</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Na</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ICaL">
<variable name="ICaL" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_CaL" units="mm_per_ms" public_interface="in"/>
<variable name="time" units="ms" public_interface="in" private_interface="out"/>
<variable name="V" units="mV" public_interface="in" private_interface="out"/>
<variable name="Cai" units="mM" public_interface="in" private_interface="out"/>
<variable name="Cao" units="mM" public_interface="in"/>
<variable name="R" units="gas_constant" public_interface="in"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="d" units="dimensionless" public_interface="in"/>
<variable name="f" units="dimensionless" public_interface="in"/>
<variable name="fCa" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICaL</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>g_CaL</ci>
<ci>d</ci>
<ci>f</ci>
<ci>fCa</ci>
<cn cellml:units="dimensionless">4</cn>
<ci>V</ci>
<apply>
<power/>
<ci>F</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>Cai</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>Cao</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IpCa">
<variable name="IpCa" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_pCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="K_pCa" units="mM" public_interface="in"/>
<variable name="Cai" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IpCa</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>g_pCa</ci>
<ci>Cai</ci>
</apply>
<apply>
<plus/>
<ci>K_pCa</ci>
<ci>Cai</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="INaCa">
<variable name="INaCa" units="uA_per_mmsq" public_interface="out"/>
<variable name="k_NaCa" units="uA_per_mmsq" public_interface="in"/>
<variable name="K_mNai" units="mM" public_interface="in"/>
<variable name="K_mCa" units="mM" public_interface="in"/>
<variable name="k_sat" units="dimensionless" public_interface="in"/>
<variable name="gamma" units="dimensionless" public_interface="in"/>
<variable name="alpha" units="dimensionless" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="R" units="gas_constant" public_interface="in"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="Nai" units="mM" public_interface="in"/>
<variable name="Nao" units="mM" public_interface="in"/>
<variable name="Cai" units="mM" public_interface="in"/>
<variable name="Cao" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INaCa</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>k_NaCa</ci>
<apply>
<minus/>
<apply>
<times/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>gamma</ci>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<power/>
<ci>Nai</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Cao</ci>
</apply>
<apply>
<times/>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>gamma</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
<apply>
<power/>
<ci>Nao</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<ci>Cai</ci>
<ci>alpha</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<power/>
<ci>K_mNai</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
<apply>
<power/>
<ci>Nao</ci>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
<apply>
<plus/>
<ci>K_mCa</ci>
<ci>Cao</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<times/>
<ci>k_sat</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>gamma</ci>
<cn cellml:units="dimensionless">1</cn>
</apply>
<ci>V</ci>
<ci>F</ci>
</apply>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="IbCa">
<variable name="IbCa" units="uA_per_mmsq" public_interface="out"/>
<variable name="g_bCa" units="mS_per_mmsq" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="E_Ca" units="mV" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IbCa</ci>
<apply>
<times/>
<ci>g_bCa</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>E_Ca</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ENa">
<variable name="z" units="dimensionless" initial_value="1"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="intracellular_concentration" units="mM" public_interface="in"/>
<variable name="extracellular_concentration" units="mM" public_interface="in"/>
<variable name="R" units="gas_constant" initial_value="8314.472" public_interface="out"/>
<variable name="F" units="faradays_constant" initial_value="96485" public_interface="out"/>
<variable name="reversal_potential" units="mV" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>reversal_potential</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<ci>z</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>extracellular_concentration</ci>
<ci>intracellular_concentration</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="EK">
<variable name="z" units="dimensionless" initial_value="1"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="intracellular_concentration" units="mM" public_interface="in"/>
<variable name="extracellular_concentration" units="mM" public_interface="in"/>
<variable name="R" units="gas_constant" initial_value="8314.472" public_interface="out"/>
<variable name="F" units="faradays_constant" initial_value="96485" public_interface="out"/>
<variable name="reversal_potential" units="mV" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>reversal_potential</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<ci>z</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>extracellular_concentration</ci>
<ci>intracellular_concentration</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ECa">
<variable name="z" units="dimensionless" initial_value="2"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="intracellular_concentration" units="mM" public_interface="in"/>
<variable name="extracellular_concentration" units="mM" public_interface="in"/>
<variable name="R" units="gas_constant" initial_value="8314.472" public_interface="out"/>
<variable name="F" units="faradays_constant" initial_value="96485" public_interface="out"/>
<variable name="reversal_potential" units="mV" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>reversal_potential</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<ci>z</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>extracellular_concentration</ci>
<ci>intracellular_concentration</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="EKs">
<variable name="z" units="dimensionless" initial_value="1"/>
<variable name="T" units="K" public_interface="in"/>
<variable name="intracellular_concentration_1" units="mM" public_interface="in"/>
<variable name="extracellular_concentration_1" units="mM" public_interface="in"/>
<variable name="intracellular_concentration_2" units="mM" public_interface="in"/>
<variable name="extracellular_concentration_2" units="mM" public_interface="in"/>
<variable name="multiplier_1" units="dimensionless" initial_value="1"/>
<variable name="multiplier_2" units="dimensionless" public_interface="in"/>
<variable name="R" units="gas_constant" initial_value="8314.472" public_interface="out"/>
<variable name="F" units="faradays_constant" initial_value="96485" public_interface="out"/>
<variable name="reversal_potential" units="mV" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>reversal_potential</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>R</ci>
<ci>T</ci>
</apply>
<apply>
<times/>
<ci>z</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<ci>multiplier_1</ci>
<ci>extracellular_concentration_1</ci>
</apply>
<apply>
<times/>
<ci>multiplier_2</ci>
<ci>extracellular_concentration_2</ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>multiplier_1</ci>
<ci>intracellular_concentration_1</ci>
</apply>
<apply>
<times/>
<ci>multiplier_2</ci>
<ci>intracellular_concentration_2</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Nai">
<variable name="Nai" units="mM" initial_value="7.39223229243676" public_interface="out"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="Na_flux" units="mM_per_ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Nai</ci>
</apply>
<apply>
<minus/>
<ci>Na_flux</ci>
</apply>
</apply>
</math>
</component>
<component name="Ki">
<variable name="Ki" units="mM" initial_value="62.3622982068174" public_interface="out"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="K_flux" units="mM_per_ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ki</ci>
</apply>
<apply>
<minus/>
<ci>K_flux</ci>
</apply>
</apply>
</math>
</component>
<component name="Cai">
<variable name="Cai" units="mM" public_interface="out"/>
<variable name="CaSR" units="mM" public_interface="out"/>
<variable name="Cai_total" units="mM" initial_value="0.00640319307218471" public_interface="out"/>
<variable name="CaSR_total" units="mM" initial_value="-5.43271749502848" public_interface="out"/>
<variable name="Cai_buf" units="mM" public_interface="out"/>
<variable name="CaSR_buf" units="mM" public_interface="out"/>
<variable name="Bufc" units="mM" public_interface="in"/>
<variable name="Kbufc" units="mM" public_interface="in"/>
<variable name="Bufsr" units="mM" public_interface="in"/>
<variable name="Kbufsr" units="mM" public_interface="in"/>
<variable name="vSR" units="dimensionless" public_interface="in"/>
<variable name="vC" units="dimensionless" public_interface="in"/>
<variable name="Am" units="per_mm" public_interface="in"/>
<variable name="F" units="faradays_constant" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="Capacitance" units="uF_per_mmsq" public_interface="in"/>
<variable name="Ca_flux" units="mM_per_ms" public_interface="in"/>
<variable name="Ca_SR_flux" units="mM_per_ms" public_interface="in"/>
<variable name="aCai" units="dimensionless"/>
<variable name="bCai" units="mM"/>
<variable name="cCai" units="mMsq"/>
<variable name="aCaSR" units="dimensionless"/>
<variable name="bCaSR" units="mM"/>
<variable name="cCaSR" units="mMsq"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>aCai</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>bCai</ci>
<apply>
<plus/>
<ci>Cai_total</ci>
<ci>Kbufc</ci>
<ci>Bufc</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>cCai</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>Bufc</ci>
</apply>
<ci>Cai_total</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Cai_buf</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<root/>
<apply>
<minus/>
<apply>
<power/>
<ci>bCai</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">4</cn>
<ci>aCai</ci>
<ci>cCai</ci>
</apply>
</apply>
</apply>
<ci>bCai</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>aCai</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Cai</ci>
<apply>
<minus/>
<ci>Cai_total</ci>
<ci>Cai_buf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Cai_total</ci>
</apply>
<apply>
<plus/>
<ci>Ca_flux</ci>
<ci>Ca_SR_flux</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>aCaSR</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>bCaSR</ci>
<apply>
<plus/>
<ci>CaSR_total</ci>
<ci>Kbufsr</ci>
<ci>Bufsr</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>cCaSR</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>Bufsr</ci>
</apply>
<ci>CaSR_total</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>CaSR_buf</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<root/>
<apply>
<minus/>
<apply>
<power/>
<ci>bCaSR</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">4</cn>
<ci>aCaSR</ci>
<ci>cCaSR</ci>
</apply>
</apply>
</apply>
<ci>bCaSR</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2</cn>
<ci>aCaSR</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>CaSR</ci>
<apply>
<minus/>
<ci>CaSR_total</ci>
<ci>CaSR_buf</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>CaSR_total</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>vC</ci>
<ci>vSR</ci>
</apply>
<apply>
<minus/>
<ci>Ca_SR_flux</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Jleak">
<variable name="Jleak" units="mM_per_ms" public_interface="out"/>
<variable name="V_leak" units="per_ms" public_interface="in"/>
<variable name="Cai" units="mM" public_interface="in"/>
<variable name="CaSR" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Jleak</ci>
<apply>
<times/>
<ci>V_leak</ci>
<apply>
<minus/>
<ci>CaSR</ci>
<ci>Cai</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Jup">
<variable name="Jup" units="mM_per_ms" public_interface="out"/>
<variable name="Vmax_up" units="mM_per_ms" public_interface="in"/>
<variable name="Cai" units="mM" public_interface="in"/>
<variable name="K_up" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Jup</ci>
<apply>
<divide/>
<ci>Vmax_up</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<power/>
<ci>K_up</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<ci>Cai</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="Jrel">
<variable name="Jrel" units="mM_per_ms" public_interface="out"/>
<variable name="Cai" units="mM" public_interface="in"/>
<variable name="CaSR" units="mM" public_interface="in"/>
<variable name="a_rel" units="mM_per_ms" public_interface="in"/>
<variable name="b_rel" units="mM" public_interface="in"/>
<variable name="c_rel" units="mM_per_ms" public_interface="in"/>
<variable name="tau_g" units="ms" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="d" units="dimensionless" public_interface="in"/>
<variable name="g" units="dimensionless" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Jrel</ci>
<apply>
<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>a_rel</ci>
<apply>
<power/>
<ci>CaSR</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<apply>
<plus/>
<apply>
<power/>
<ci>b_rel</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
<apply>
<power/>
<ci>CaSR</ci>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<ci>c_rel</ci>
</apply>
<ci>d</ci>
<ci>g</ci>
</apply>
</apply>
</math>
</component>
<component name="m_gate">
<variable name="m" units="dimensionless" initial_value="0.0866469000318477" public_interface="out"/>
<variable name="tau_m" units="ms" public_interface="out"/>
<variable name="m_infinity" units="dimensionless" public_interface="out"/>
<variable name="alpha_m" units="per_ms"/>
<variable name="beta_m" units="per_ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>m_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">56.86</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">9.03</cn>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_m</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">60</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_m</ci>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="per_ms">0.1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">35</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">5</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="per_ms">0.1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="mV">50</cn>
</apply>
<cn cellml:units="mV">200</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_m</ci>
<apply>
<times/>
<cn cellml:units="mscu">1</cn>
<ci>alpha_m</ci>
<ci>beta_m</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>m</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>m_infinity</ci>
<ci>m</ci>
</apply>
<ci>tau_m</ci>
</apply>
</apply>
</math>
</component>
<component name="h_gate">
<variable name="h" units="dimensionless" initial_value="0.0814742345064571" public_interface="out"/>
<variable name="tau_h" units="ms" public_interface="out"/>
<variable name="h_infinity" units="dimensionless" public_interface="out"/>
<variable name="alpha_h" units="per_ms"/>
<variable name="beta_h" units="per_ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>h_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">71.55</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">7.43</cn>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_h</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="per_ms">0.057</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<cn cellml:units="mV">80</cn>
<ci>V</ci>
</apply>
</apply>
<cn cellml:units="mV">6.8</cn>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="per_ms">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_h</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="per_ms">2.7</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.079</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn type="e-notation" cellml:units="per_ms">3.1 <sep/>
5</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.3485</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.77</cn>
<apply>
<times/>
<cn cellml:units="ms">0.13</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">10.66</cn>
</apply>
</apply>
<cn cellml:units="mV">11.1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_h</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_h</ci>
<ci>beta_h</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>h</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>h_infinity</ci>
<ci>h</ci>
</apply>
<ci>tau_h</ci>
</apply>
</apply>
</math>
</component>
<component name="j_gate">
<variable name="j" units="dimensionless" initial_value="0.0445382453674896" public_interface="out"/>
<variable name="tau_j" units="ms" public_interface="out"/>
<variable name="j_infinity" units="dimensionless" public_interface="out"/>
<variable name="alpha_j" units="per_ms"/>
<variable name="beta_j" units="per_ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>j_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">71.55</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">7.43</cn>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_j</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<minus/>
<cn type="e-notation" cellml:units="per_mV_per_ms">2.5428 <sep/>
4</cn>
</apply>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.2444</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn type="e-notation" cellml:units="per_mV_per_ms">6.948 <sep/>
-6</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.04391</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">37.78</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.311</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">79.23</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="per_ms">0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>beta_j</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_ms">0.02424</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.01052</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.1378</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">40.14</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_ms">0.6</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.057</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.1</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">32</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>tau_j</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<ci>alpha_j</ci>
<ci>beta_j</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>j</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>j_infinity</ci>
<ci>j</ci>
</apply>
<ci>tau_j</ci>
</apply>
</apply>
</math>
</component>
<component name="K1_gate">
<variable name="K1_infinity" units="dimensionless" public_interface="out"/>
<variable name="alpha_K1" units="dimensionless"/>
<variable name="beta_K1" units="dimensionless"/>
<variable name="E_K" units="mV" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>K1_infinity</ci>
<apply>
<divide/>
<ci>alpha_K1</ci>
<apply>
<plus/>
<ci>alpha_K1</ci>
<ci>beta_K1</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_K1</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.06</cn>
<apply>
<minus/>
<ci>V</ci>
<apply>
<plus/>
<ci>E_K</ci>
<cn cellml:units="mV">200</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_K1</ci>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.0002</cn>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
<cn cellml:units="mV">100</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.1</cn>
<apply>
<minus/>
<ci>V</ci>
<apply>
<plus/>
<ci>E_K</ci>
<cn cellml:units="mV">10</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.5</cn>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>E_K</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="r_gate">
<variable name="r" units="dimensionless" initial_value="7.33403191056144e-7" public_interface="out"/>
<variable name="r_infinity" units="dimensionless"/>
<variable name="tau_r" units="ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>r</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>r_infinity</ci>
<ci>r</ci>
</apply>
<ci>tau_r</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>r_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="mV">20</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_r</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="ms">9.5</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<power/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">40</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="mVsq">1800</cn>
</apply>
</apply>
</apply>
<cn cellml:units="ms">0.8</cn>
</apply>
</apply>
</math>
</component>
<component name="s_gate">
<variable name="s" units="dimensionless" initial_value="0.99980780778701" public_interface="out"/>
<variable name="s_infinity" units="dimensionless"/>
<variable name="tau_s" units="ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>s</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>s_infinity</ci>
<ci>s</ci>
</apply>
<ci>tau_s</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>s_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">20</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_s</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="ms">85</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<power/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">45</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="mVsq">320</cn>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="ms">5</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="mV">20</cn>
</apply>
<cn cellml:units="mV">5</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="ms">3</cn>
</apply>
</apply>
</math>
</component>
<component name="Xr1_gate">
<variable name="Xr1" units="dimensionless" initial_value="0.364725483215666" public_interface="out"/>
<variable name="alpha_Xr1" units="per_ms"/>
<variable name="beta_Xr1" units="per_ms"/>
<variable name="Xr1_infinity" units="dimensionless"/>
<variable name="tau_Xr1" units="ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Xr1</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Xr1_infinity</ci>
<ci>Xr1</ci>
</apply>
<ci>tau_Xr1</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Xr1_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">26</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_Xr1</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">450</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">45</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">10</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_Xr1</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">6</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">30</cn>
</apply>
<cn cellml:units="mV">11.5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_Xr1</ci>
<apply>
<times/>
<cn cellml:units="mscu">1</cn>
<ci>alpha_Xr1</ci>
<ci>beta_Xr1</ci>
</apply>
</apply>
</math>
</component>
<component name="Xr2_gate">
<variable name="Xr2" units="dimensionless" initial_value="0.275169025815548" public_interface="out"/>
<variable name="alpha_Xr2" units="per_ms"/>
<variable name="beta_Xr2" units="per_ms"/>
<variable name="Xr2_infinity" units="dimensionless"/>
<variable name="tau_Xr2" units="ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Xr2</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Xr2_infinity</ci>
<ci>Xr2</ci>
</apply>
<ci>tau_Xr2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Xr2_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">88</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">24</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_Xr2</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">3</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">60</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">20</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_Xr2</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">1.12</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="mV">60</cn>
</apply>
<cn cellml:units="mV">20</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_Xr2</ci>
<apply>
<times/>
<cn cellml:units="mscu">1</cn>
<ci>alpha_Xr2</ci>
<ci>beta_Xr2</ci>
</apply>
</apply>
</math>
</component>
<component name="Xs_gate">
<variable name="Xs" units="dimensionless" initial_value="0.0138157627500838" public_interface="out"/>
<variable name="alpha_Xs" units="per_ms"/>
<variable name="beta_Xs" units="per_ms"/>
<variable name="Xs_infinity" units="dimensionless"/>
<variable name="tau_Xs" units="ms"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Xs</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>Xs_infinity</ci>
<ci>Xs</ci>
</apply>
<ci>tau_Xs</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Xs_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">5</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">14</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_Xs</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">1100</cn>
<apply>
<root/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">10</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_Xs</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
<cn cellml:units="mV">60</cn>
</apply>
<cn cellml:units="mV">20</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_Xs</ci>
<apply>
<times/>
<cn cellml:units="mscu">1</cn>
<ci>alpha_Xs</ci>
<ci>beta_Xs</ci>
</apply>
</apply>
</math>
</component>
<component name="d_gate">
<variable name="d" units="dimensionless" initial_value="0.000346485795707982" public_interface="out"/>
<variable name="alpha_d" units="per_ms" public_interface="out"/>
<variable name="beta_d" units="per_ms" public_interface="out"/>
<variable name="tau_d" units="ms" public_interface="out"/>
<variable name="gamma_d" units="ms" public_interface="out"/>
<variable name="d_infinity" units="dimensionless" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>d_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">5</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">7.5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_d</ci>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="per_ms">1.4</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">35</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">13</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="per_ms">0.25</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_d</ci>
<apply>
<divide/>
<cn cellml:units="per_ms">1.4</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">5</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gamma_d</ci>
<apply>
<divide/>
<cn cellml:units="ms">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="mV">50</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">20</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="mscu">1</cn>
<ci>alpha_d</ci>
<ci>beta_d</ci>
</apply>
<ci>gamma_d</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_infinity</ci>
<ci>d</ci>
</apply>
<ci>tau_d</ci>
</apply>
</apply>
</math>
</component>
<component name="f_gate">
<variable name="f" units="dimensionless" initial_value="0.9951755361259" public_interface="out"/>
<variable name="tau_f" units="ms" public_interface="out"/>
<variable name="f_infinity" units="dimensionless" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>f_infinity</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="mV">20</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_f</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="ms">1125</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<power/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">27</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
<cn cellml:units="mVsq">240</cn>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="ms">165</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="mV">25</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">10</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="ms">80</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_infinity</ci>
<ci>f</ci>
</apply>
<ci>tau_f</ci>
</apply>
</apply>
</math>
</component>
<component name="fCa_gate">
<variable name="fCa" units="dimensionless" initial_value="1.0069809740354" public_interface="out"/>
<variable name="alpha_fCa" units="dimensionless"/>
<variable name="beta_fCa" units="dimensionless"/>
<variable name="tau_fCa" units="ms" initial_value="2" public_interface="out"/>
<variable name="gamma_fCa" units="dimensionless"/>
<variable name="fCa_infinity" units="dimensionless" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="Cai" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>fCa_infinity</ci>
<apply>
<divide/>
<apply>
<plus/>
<ci>alpha_fCa</ci>
<ci>beta_fCa</ci>
<ci>gamma_fCa</ci>
<cn cellml:units="dimensionless">0.23</cn>
</apply>
<cn cellml:units="dimensionless">1.46</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>alpha_fCa</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Cai</ci>
<cn cellml:units="mM">0.000325</cn>
</apply>
<cn cellml:units="dimensionless">8</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>beta_fCa</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Cai</ci>
<cn cellml:units="mM">0.0005</cn>
</apply>
<cn cellml:units="mM">0.0001</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gamma_fCa</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.2</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Cai</ci>
<cn cellml:units="mM">0.00075</cn>
</apply>
<cn cellml:units="mM">0.0008</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fCa</ci>
</apply>
<piecewise>
<piece>
<cn cellml:units="per_ms">0</cn>
<apply>
<and/>
<apply>
<gt/>
<ci>fCa_infinity</ci>
<ci>fCa</ci>
</apply>
<apply>
<gt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">60</cn>
</apply>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<minus/>
<ci>fCa_infinity</ci>
<ci>fCa</ci>
</apply>
<ci>tau_fCa</ci>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="g_gate">
<variable name="g" units="dimensionless" initial_value="0.99999345944766" public_interface="out"/>
<variable name="g_infinity" units="dimensionless" public_interface="out"/>
<variable name="tau_g" units="ms" public_interface="in"/>
<variable name="Cai" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>g_infinity</ci>
<piecewise>
<piece>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<power/>
<ci>Cai</ci>
<cn cellml:units="dimensionless">6</cn>
</apply>
<apply>
<power/>
<cn cellml:units="mM">0.00035</cn>
<cn cellml:units="dimensionless">6</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<leq/>
<ci>Cai</ci>
<cn cellml:units="mM">0.00035</cn>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1</cn>
<apply>
<divide/>
<apply>
<power/>
<ci>Cai</ci>
<cn cellml:units="dimensionless">16</cn>
</apply>
<apply>
<power/>
<cn cellml:units="mM">0.00035</cn>
<cn cellml:units="dimensionless">16</cn>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>g</ci>
</apply>
<piecewise>
<piece>
<cn cellml:units="per_ms">0</cn>
<apply>
<and/>
<apply>
<gt/>
<ci>g_infinity</ci>
<ci>g</ci>
</apply>
<apply>
<gt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">60</cn>
</apply>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<minus/>
<ci>g_infinity</ci>
<ci>g</ci>
</apply>
<ci>tau_g</ci>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<component name="NL_model">
<variable name="xHalfSL" units="dimensionless"/>
<variable name="Cai_in" units="millimolar" public_interface="in"/>
<variable name="ForceExt" units="mN_per_mm2" public_interface="out"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="cTnCaEff" units="millimolar"/>
<variable name="cTnCa" units="millimolar" initial_value="0.059790672481515"/>
<variable name="cTnCaCB" units="millimolar" initial_value="0.00990501329914472"/>
<variable name="cTnCB" units="millimolar" initial_value="0.00156766416391726"/>
<variable name="Q_a" units="per_millisecond"/>
<variable name="Q_b" units="per_millisecond"/>
<variable name="Q_r" units="per_millisecond"/>
<variable name="Q_d" units="per_millisecond"/>
<variable name="Q_d1" units="per_millisecond"/>
<variable name="Q_d2" units="per_millisecond"/>
<variable name="Y_1" units="per_millimolar_millisecond" initial_value="39"/>
<variable name="Y_2" units="per_millisecond" initial_value="0.0039"/>
<variable name="Y_3" units="per_millisecond" initial_value="0.03"/>
<variable name="Y_4" units="per_millisecond" initial_value="0.12"/>
<variable name="Y_d" units="ms" initial_value="0.027"/>
<variable name="Z_1" units="per_millisecond" initial_value="0.03"/>
<variable name="Z_2" units="per_millisecond" initial_value="0.0039"/>
<variable name="Z_3" units="per_millimolar_millisecond" initial_value="1560"/>
<variable name="OptiHSL" units="dimensionless" initial_value="1.17"/>
<variable name="xLLimitCB" units="dimensionless" initial_value="0.005"/>
<variable name="R" units="dimensionless" initial_value="2"/>
<variable name="SlidingR" units="per_ms" initial_value="1.2"/>
<variable name="xInext" units="dimensionless" initial_value="0.741096216822752"/>
<variable name="cTn" units="millimolar"/>
<variable name="trpnbar" units="millimolar" initial_value="0.06"/>
<variable name="cCaTropC" units="millimolar"/>
<variable name="xhhh" units="dimensionless"/>
<variable name="cTRPN" units="millimolar" public_interface="out"/>
<variable name="AForceCB" units="mN_per_mm2" initial_value="1800000"/>
<variable name="xNewCBF" units="mN_per_mm2"/>
<variable name="xKcoeff" units="mN_per_mm2" initial_value="140000"/>
<variable name="xKcoeff2" units="mN_per_mm2" initial_value="30"/>
<variable name="ForceP" units="mN_per_mm2"/>
<variable name="ForceB" units="mN_per_mm2"/>
<variable name="V_LV" units="mL" public_interface="in"/>
<variable name="radiusLV" units="micrometre"/>
<variable name="Fmult" units="dimensionless" initial_value="1.2"/>
<variable name="Tension" units="mN_per_mm2"/>
<variable name="P_LV" units="mmHg" public_interface="out"/>
<variable name="offset" units="mmHg" initial_value="0"/>
<variable name="xDen" units="micrometre" initial_value="236550"/>
<variable name="Cai" units="millimolar"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Cai</ci>
<ci>Cai_in</ci>
</apply>
<apply>
<eq/>
<ci>radiusLV</ci>
<apply>
<power/>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">3</cn>
<ci>V_LV</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<pi/>
</apply>
<apply>
<divide/>
<cn cellml:units="dimensionless">1</cn>
<cn cellml:units="dimensionless">3</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>xHalfSL</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="dimensionless">10000</cn>
<cn cellml:units="dimensionless">2</cn>
<pi/>
<ci>radiusLV</ci>
</apply>
<ci>xDen</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Tension</ci>
<apply>
<times/>
<ci>ForceExt</ci>
<ci>Fmult</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>P_LV</ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="micrometre">2</cn>
<ci>Tension</ci>
</apply>
<ci>radiusLV</ci>
</apply>
<cn cellml:units="dimensionless">1000</cn>
</apply>
<cn cellml:units="dimensionless">133</cn>
</apply>
<ci>offset</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>xInext</ci>
</apply>
<apply>
<times/>
<ci>SlidingR</ci>
<apply>
<minus/>
<apply>
<minus/>
<ci>xHalfSL</ci>
<ci>xInext</ci>
</apply>
<ci>xLLimitCB</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>cTn</ci>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="millimolar">1</cn>
<ci>cTnCa</ci>
</apply>
<ci>cTnCaCB</ci>
</apply>
<ci>cTnCB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Q_b</ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>Y_1</ci>
<ci>Cai</ci>
<ci>cTn</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Z_1</ci>
<ci>cTnCa</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>cTnCaEff</ci>
<apply>
<divide/>
<ci>cTnCa</ci>
<apply>
<exp/>
<apply>
<times/>
<ci>R</ci>
<apply>
<power/>
<apply>
<minus/>
<ci>xHalfSL</ci>
<ci>OptiHSL</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Q_a</ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>Y_2</ci>
<ci>cTnCaEff</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Z_2</ci>
<ci>cTnCaCB</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Q_r</ci>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<times/>
<ci>Y_3</ci>
<ci>cTnCaCB</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>Z_3</ci>
<ci>cTnCB</ci>
<ci>Cai</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Q_d1</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Y_d</ci>
<apply>
<power/>
<apply>
<times/>
<ci>SlidingR</ci>
<apply>
<minus/>
<apply>
<minus/>
<ci>xHalfSL</ci>
<ci>xInext</ci>
</apply>
<ci>xLLimitCB</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>cTnCaCB</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Q_d</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Y_4</ci>
<ci>cTnCB</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Q_d2</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Y_d</ci>
<apply>
<power/>
<apply>
<times/>
<ci>SlidingR</ci>
<apply>
<minus/>
<apply>
<minus/>
<ci>xHalfSL</ci>
<ci>xInext</ci>
</apply>
<ci>xLLimitCB</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
<ci>cTnCB</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>cCaTropC</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>trpnbar</ci>
<apply>
<minus/>
<apply>
<plus/>
<ci>Q_r</ci>
<ci>Q_d2</ci>
</apply>
<ci>Q_b</ci>
</apply>
</apply>
<cn cellml:units="per_millisecond">1</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cTnCa</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>Q_b</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
<apply>
<times/>
<ci>Q_a</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cTnCaCB</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>Q_a</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
<apply>
<times/>
<ci>Q_r</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
<apply>
<times/>
<ci>Q_d1</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>cTnCB</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>Q_r</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
<apply>
<times/>
<ci>Q_d</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
<apply>
<times/>
<ci>Q_d2</ci>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>xhhh</ci>
<apply>
<minus/>
<ci>xHalfSL</ci>
<ci>xInext</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>cTRPN</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>cTnCaCB</ci>
<ci>cTnCB</ci>
</apply>
<ci>trpnbar</ci>
</apply>
<cn cellml:units="millimolar">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>xNewCBF</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>AForceCB</ci>
<apply>
<plus/>
<ci>cTnCaCB</ci>
<ci>cTnCB</ci>
</apply>
<ci>trpnbar</ci>
</apply>
<cn cellml:units="millimolar2">1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ForceP</ci>
<piecewise>
<piece>
<apply>
<times/>
<ci>xKcoeff</ci>
<apply>
<power/>
<apply>
<minus/>
<ci>xHalfSL</ci>
<cn cellml:units="dimensionless">0.97</cn>
</apply>
<cn cellml:units="dimensionless">5</cn>
</apply>
</apply>
<apply>
<gt/>
<ci>xHalfSL</ci>
<cn cellml:units="dimensionless">0.97</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<ci>xKcoeff2</ci>
<apply>
<minus/>
<ci>xHalfSL</ci>
<cn cellml:units="dimensionless">0.97</cn>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ForceB</ci>
<apply>
<times/>
<ci>xNewCBF</ci>
<ci>xhhh</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ForceExt</ci>
<apply>
<plus/>
<ci>ForceP</ci>
<ci>ForceB</ci>
</apply>
</apply>
</math>
</component>
<component name="lung">
<variable name="time" units="ms" public_interface="in"/>
<variable name="F_PC" units="L_per_sec" public_interface="in"/>
<variable name="V_PC" units="mL" public_interface="in"/>
<variable name="F_MU" units="L_per_sec" public_interface="in"/>
<variable name="V_MU" units="mL" public_interface="in"/>
<variable name="Fpc" units="liter_per_min"/>
<variable name="Fsc" units="liter_per_min"/>
<variable name="Vpc" units="mL"/>
<variable name="Vsc" units="mL"/>
<variable name="Tbody" units="kelvin" initial_value="300"/>
<variable name="Pstp" units="mmHg" initial_value="760"/>
<variable name="Tstp" units="kelvin" initial_value="273"/>
<variable name="PO2_pc" units="mmHg" initial_value="58.5987098171338"/>
<variable name="PO2_sc" units="mmHg" initial_value="3.98485499218493"/>
<variable name="nH" units="dimensionless" initial_value="3.5"/>
<variable name="P50_O2" units="mmHg" initial_value="26.5"/>
<variable name="SHbO2_pc" units="dimensionless"/>
<variable name="SHbO2_sc" units="dimensionless"/>
<variable name="dSHbO2dPO2_pc" units="per_mmHg"/>
<variable name="dSHbO2dPO2_sc" units="per_mmHg"/>
<variable name="CHb" units="mole" initial_value="0.0204"/>
<variable name="H" units="dimensionless" initial_value="0.45"/>
<variable name="alphaO2" units="mole_per_mmHg" initial_value="1.36e-6"/>
<variable name="CtO2_pc" units="mole"/>
<variable name="CtO2_sc" units="mole"/>
<variable name="PA_O2" units="mmHg" initial_value="84.5907622728202"/>
<variable name="DL_O2" units="mlSTPD_per_s_per_mmHg"/>
<variable name="Vpcmax" units="liter" initial_value="0.07125"/>
<variable name="PO2_isf" units="mmHg" initial_value="0.000255720054332517"/>
<variable name="Visf" units="mL" initial_value="48000"/>
<variable name="PS" units="mL_per_min" initial_value="600000"/>
<variable name="Vcytox" units="mole_per_min" initial_value="0.0126"/>
<variable name="Kcytox" units="mole" initial_value="1e-9"/>
<variable name="V_O2" units="mole_per_min"/>
<variable name="O2flux" units="mL_per_min"/>
<variable name="PCO2_pc" units="mmHg" initial_value="27.0873474614805"/>
<variable name="PCO2_sc" units="mmHg" initial_value="74.7200600017978"/>
<variable name="P50_CO2" units="mmHg" initial_value="250"/>
<variable name="SHbCO2_pc" units="dimensionless"/>
<variable name="SHbCO2_sc" units="dimensionless"/>
<variable name="dSHbCO2dPCO2_pc" units="per_mmHg"/>
<variable name="alphaCO2" units="mole_per_mmHg" initial_value="3.264e-5"/>
<variable name="CtCO2_pc" units="mole"/>
<variable name="dSHbCO2dPCO2_sc" units="per_mmHg"/>
<variable name="CtCO2_sc" units="mole"/>
<variable name="PA_CO2" units="mmHg" initial_value="26.9281383029831"/>
<variable name="DL_CO2" units="mlSTPD_per_s_per_mmHg"/>
<variable name="PCO2_isf" units="mmHg" initial_value="74.7805551351833"/>
<variable name="RQ" units="dimensionless" initial_value="0.8"/>
<variable name="V_CO2" units="mole_per_min"/>
<variable name="CO2flux" units="mL_per_min"/>
<variable name="QdotCA" units="mL_per_s"/>
<variable name="QdotDC" units="mL_per_s"/>
<variable name="QdotED" units="mL_per_s"/>
<variable name="Pao" units="mmHg" initial_value="760"/>
<variable name="PH2O" units="mmHg" initial_value="47"/>
<variable name="Pao_O2" units="mmHg"/>
<variable name="Pao_CO2" units="mmHg"/>
<variable name="Pao_N2" units="mmHg"/>
<variable name="PD_O2" units="mmHg" initial_value="137.481485816086"/>
<variable name="PC_O2" units="mmHg" initial_value="129.526915731438"/>
<variable name="PD_N2" units="mmHg"/>
<variable name="PC_N2" units="mmHg"/>
<variable name="PA_N2" units="mmHg"/>
<variable name="Rs" units="cmH2O_sec_per_L"/>
<variable name="Rc" units="cmH2O_sec_per_L"/>
<variable name="Ru" units="cmH2O_sec_per_L"/>
<variable name="Vc" units="L" initial_value="0.0807533336512639"/>
<variable name="dV" units="L" initial_value="3.38422831502523"/>
<variable name="Vcw" units="L"/>
<variable name="VA" units="L" initial_value="3.24550268572493"/>
<variable name="Vve" units="L" initial_value="-0.07949414"/>
<variable name="Pcw" units="cmH2O"/>
<variable name="Pl" units="cmH2O"/>
<variable name="PA" units="cmH2O"/>
<variable name="Pc" units="cmH2O"/>
<variable name="Pve" units="cmH2O"/>
<variable name="Ppl" units="cmH2O"/>
<variable name="PplmmHg" units="mmHg"/>
<variable name="PD" units="cmH2O"/>
<variable name="Pmus" units="cmH2O"/>
<variable name="RV" units="L" initial_value="1.9"/>
<variable name="TLC" units="L" initial_value="7.3"/>
<variable name="VD" units="L" initial_value="0.185"/>
<variable name="f" units="per_min" initial_value="15"/>
<variable name="Ac" units="cmH2O" initial_value="7.09"/>
<variable name="Acw" units="cmH2O" initial_value="1.4"/>
<variable name="Al" units="cmH2O" initial_value="0.2"/>
<variable name="As" units="cmH2O_sec_per_L" initial_value="2.2"/>
<variable name="Au" units="cmH2O_sec_per_L" initial_value="0.34"/>
<variable name="Bc" units="cmH2O" initial_value="37.3"/>
<variable name="Bcp" units="cmH2O" initial_value="3.73"/>
<variable name="Bcw" units="cmH2O" initial_value="-3.5"/>
<variable name="Bl" units="cmH2O" initial_value="-0.5"/>
<variable name="Bs" units="cmH2O" initial_value="0.02"/>
<variable name="Cve" units="L_per_cmH2O" initial_value="0.5"/>
<variable name="Kc" units="cmH2O_sec_per_L" initial_value="0.21"/>
<variable name="Kl" units="per_L" initial_value="1"/>
<variable name="Ks" units="dimensionless" initial_value="-10.9"/>
<variable name="Ku" units="cmH2O_sec2_per_L2" initial_value="0.46"/>
<variable name="Vstar" units="L" initial_value="5.3"/>
<variable name="Vcmax" units="L" initial_value="0.185"/>
<variable name="tau" units="second" initial_value="0.1"/>
<variable name="Amus" units="cmH2O" initial_value="2"/>
<variable name="PD_CO2" units="mmHg" initial_value="5.25565008853068"/>
<variable name="PC_CO2" units="mmHg" initial_value="8.52962553969249"/>
<variable name="dVdt" units="dimensionless"/>
<variable name="dVcdt" units="dimensionless"/>
<variable name="dVAdt" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Fpc</ci>
<apply>
<times/>
<ci>F_PC</ci>
<cn cellml:units="dimensionless">0.06</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Fsc</ci>
<apply>
<times/>
<ci>F_MU</ci>
<cn cellml:units="dimensionless">0.06</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Vpc</ci>
<ci>V_PC</ci>
</apply>
<apply>
<eq/>
<ci>Vsc</ci>
<ci>V_MU</ci>
</apply>
<apply>
<eq/>
<ci>DL_CO2</ci>
<apply>
<times/>
<apply>
<root/>
<apply>
<divide/>
<ci>Vpc</ci>
<ci>Vpcmax</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">16.67</cn>
<cn cellml:units="dimensionless">0.0316227766016838</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Pao_O2</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>Pao</ci>
<ci>PH2O</ci>
</apply>
<cn cellml:units="dimensionless">0.21</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Pao_CO2</ci>
<apply>
<times/>
<apply>
<minus/>
<ci>Pao</ci>
<ci>PH2O</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">3 <sep/>
-4</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>SHbO2_pc</ci>
<apply>
<divide/>
<apply>
<power/>
<apply>
<divide/>
<ci>PO2_pc</ci>
<ci>P50_O2</ci>
</apply>
<ci>nH</ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<divide/>
<ci>PO2_pc</ci>
<ci>P50_O2</ci>
</apply>
<ci>nH</ci>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>SHbO2_sc</ci>
<apply>
<divide/>
<apply>
<power/>
<apply>
<divide/>
<ci>PO2_sc</ci>
<ci>P50_O2</ci>
</apply>
<ci>nH</ci>
</apply>
<apply>
<plus/>
<apply>
<power/>
<apply>
<divide/>
<ci>PO2_sc</ci>
<ci>P50_O2</ci>
</apply>
<ci>nH</ci>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>dSHbO2dPO2_pc</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>nH</ci>
<apply>
<power/>
<ci>PO2_pc</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>PO2_pc</ci>
<ci>P50_O2</ci>
</apply>
<ci>nH</ci>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<apply>
<power/>
<apply>
<divide/>
<ci>PO2_pc</ci>
<ci>P50_O2</ci>
</apply>
<ci>nH</ci>
</apply>
<cn cellml:units="dimensionless">1</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>dSHbO2dPO2_sc</ci>
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<times/>
<ci>nH</ci>
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<power/>
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<minus/>
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<power/>
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<divide/>
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<eq/>
<ci>CtO2_pc</ci>
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<plus/>
<apply>
<times/>
<ci>alphaO2</ci>
<ci>PO2_pc</ci>
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<times/>
<ci>CHb</ci>
<ci>SHbO2_pc</ci>
<ci>H</ci>
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<eq/>
<ci>CtO2_sc</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>alphaO2</ci>
<ci>PO2_sc</ci>
</apply>
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<times/>
<ci>CHb</ci>
<ci>SHbO2_sc</ci>
<ci>H</ci>
</apply>
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<eq/>
<ci>DL_O2</ci>
<apply>
<times/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<root/>
<apply>
<divide/>
<ci>Vpc</ci>
<ci>Vpcmax</ci>
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<minus/>
<apply>
<plus/>
<cn cellml:units="dimensionless">0.397</cn>
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<times/>
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<ci>PO2_pc</ci>
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<times/>
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-4</cn>
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<power/>
<ci>PO2_pc</ci>
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<times/>
<cn type="e-notation" cellml:units="dimensionless">5.1 <sep/>
-7</cn>
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<eq/>
<ci>V_O2</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>Vcytox</ci>
<ci>alphaO2</ci>
<ci>PO2_isf</ci>
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<plus/>
<ci>Kcytox</ci>
<apply>
<times/>
<ci>alphaO2</ci>
<ci>PO2_isf</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>O2flux</ci>
<apply>
<times/>
<ci>DL_O2</ci>
<apply>
<minus/>
<ci>PA_O2</ci>
<ci>PO2_pc</ci>
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<cn cellml:units="dimensionless">22400</cn>
<cn cellml:units="dimensionless">0.002678571428571428</cn>
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<eq/>
<ci>SHbCO2_pc</ci>
<apply>
<divide/>
<apply>
<divide/>
<ci>PCO2_pc</ci>
<ci>P50_CO2</ci>
</apply>
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<plus/>
<apply>
<divide/>
<ci>PO2_pc</ci>
<ci>P50_CO2</ci>
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<cn cellml:units="dimensionless">1</cn>
</apply>
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<eq/>
<ci>SHbCO2_sc</ci>
<apply>
<divide/>
<apply>
<divide/>
<ci>PCO2_sc</ci>
<ci>P50_CO2</ci>
</apply>
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<plus/>
<apply>
<divide/>
<ci>PCO2_sc</ci>
<ci>P50_CO2</ci>
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<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
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<apply>
<eq/>
<ci>dSHbCO2dPCO2_pc</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<power/>
<ci>PCO2_pc</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<ci>PCO2_pc</ci>
</apply>
<ci>P50_CO2</ci>
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<power/>
<apply>
<plus/>
<apply>
<divide/>
<ci>PCO2_pc</ci>
<ci>P50_CO2</ci>
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<cn cellml:units="dimensionless">1</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
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<apply>
<eq/>
<ci>dSHbCO2dPCO2_sc</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<power/>
<ci>PCO2_sc</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
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<ci>PCO2_sc</ci>
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<ci>P50_CO2</ci>
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<power/>
<apply>
<plus/>
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<divide/>
<ci>PCO2_sc</ci>
<ci>P50_CO2</ci>
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<cn cellml:units="dimensionless">1</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
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<apply>
<eq/>
<ci>CtCO2_pc</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>alphaCO2</ci>
<ci>PCO2_pc</ci>
</apply>
<apply>
<times/>
<ci>CHb</ci>
<ci>SHbCO2_pc</ci>
<ci>H</ci>
</apply>
</apply>
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<apply>
<eq/>
<ci>CtCO2_sc</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>alphaCO2</ci>
<ci>PCO2_sc</ci>
</apply>
<apply>
<times/>
<ci>CHb</ci>
<ci>SHbCO2_sc</ci>
<ci>H</ci>
</apply>
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<apply>
<eq/>
<ci>V_CO2</ci>
<apply>
<times/>
<ci>RQ</ci>
<ci>V_O2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>CO2flux</ci>
<apply>
<times/>
<ci>DL_CO2</ci>
<apply>
<minus/>
<ci>PA_CO2</ci>
<ci>PCO2_pc</ci>
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<cn cellml:units="dimensionless">22400</cn>
<cn cellml:units="dimensionless">0.002678571428571428</cn>
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<eq/>
<ci>Rc</ci>
<apply>
<times/>
<ci>Kc</ci>
<apply>
<power/>
<apply>
<divide/>
<ci>Vcmax</ci>
<ci>Vc</ci>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Rs</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>As</ci>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<times/>
<ci>Ks</ci>
<apply>
<minus/>
<ci>VA</ci>
<ci>RV</ci>
</apply>
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<apply>
<minus/>
<ci>Vstar</ci>
<ci>RV</ci>
</apply>
</apply>
</apply>
</apply>
<ci>Bs</ci>
</apply>
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<apply>
<eq/>
<ci>Pl</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Al</ci>
<apply>
<exp/>
<apply>
<times/>
<ci>Kl</ci>
<ci>VA</ci>
</apply>
</apply>
</apply>
<ci>Bl</ci>
</apply>
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<apply>
<eq/>
<ci>Pmus</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Amus</ci>
<apply>
<sin/>
<apply>
<times/>
<cn cellml:units="dimensionless">6.283185307179586</cn>
<ci>f</ci>
<ci>time</ci>
<cn type="e-notation" cellml:units="dimensionless">1.6666666666666667 <sep/>
-5</cn>
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<ci>Amus</ci>
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<apply>
<eq/>
<ci>Pc</ci>
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<piece>
<apply>
<minus/>
<ci>Ac</ci>
<apply>
<times/>
<ci>Bc</ci>
<apply>
<power/>
<apply>
<minus/>
<apply>
<divide/>
<ci>Vc</ci>
<ci>Vcmax</ci>
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<cn cellml:units="dimensionless">0.7</cn>
</apply>
<cn cellml:units="dimensionless">2</cn>
</apply>
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<lt/>
<apply>
<divide/>
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<ci>Vcmax</ci>
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<cn cellml:units="dimensionless">0.5</cn>
</apply>
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<minus/>
<cn cellml:units="dimensionless">5.6</cn>
<apply>
<times/>
<ci>Bcp</ci>
<apply>
<log/>
<apply>
<minus/>
<apply>
<divide/>
<ci>Vcmax</ci>
<ci>Vc</ci>
</apply>
<cn cellml:units="dimensionless">0.999</cn>
</apply>
</apply>
</apply>
</apply>
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<eq/>
<ci>Pve</ci>
<apply>
<divide/>
<ci>Vve</ci>
<ci>Cve</ci>
</apply>
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<apply>
<eq/>
<ci>Vcw</ci>
<apply>
<plus/>
<ci>VA</ci>
<ci>VD</ci>
</apply>
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<apply>
<eq/>
<ci>Pcw</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>Acw</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1</cn>
</apply>
</apply>
<apply>
<times/>
<ci>Bcw</ci>
<apply>
<log/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<ci>TLC</ci>
<ci>RV</ci>
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<apply>
<minus/>
<ci>Vcw</ci>
<ci>RV</ci>
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</apply>
<cn cellml:units="dimensionless">0.999</cn>
</apply>
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<eq/>
<ci>Ppl</ci>
<apply>
<minus/>
<ci>Pcw</ci>
<ci>Pmus</ci>
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<eq/>
<ci>PA</ci>
<apply>
<plus/>
<ci>Ppl</ci>
<ci>Pl</ci>
<ci>Pve</ci>
</apply>
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<apply>
<eq/>
<ci>QdotCA</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>Pc</ci>
<ci>Ppl</ci>
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<ci>PA</ci>
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<ci>Rs</ci>
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<cn cellml:units="dimensionless">1000.0000000000001</cn>
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<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>dV</ci>
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<times/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vcw</ci>
<ci>dV</ci>
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<ci>tau</ci>
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<cn cellml:units="dimensionless">0.001</cn>
</apply>
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<eq/>
<ci>dVdt</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<ci>Vcw</ci>
<ci>dV</ci>
</apply>
<ci>tau</ci>
</apply>
<cn cellml:units="dimensionless">0.001</cn>
</apply>
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<eq/>
<ci>Ru</ci>
<apply>
<plus/>
<ci>Au</ci>
<apply>
<times/>
<ci>Ku</ci>
<apply>
<abs/>
<ci>dVdt</ci>
</apply>
<cn cellml:units="dimensionless">1000.0000000000006</cn>
</apply>
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<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Vc</ci>
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<times/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pmus</ci>
<ci>Pc</ci>
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<ci>Pcw</ci>
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<apply>
<plus/>
<ci>Ru</ci>
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<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pc</ci>
<ci>Pl</ci>
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<ci>Pve</ci>
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<ci>Rs</ci>
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<cn cellml:units="dimensionless">0.001</cn>
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<eq/>
<ci>dVcdt</ci>
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<times/>
<apply>
<minus/>
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<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pmus</ci>
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<ci>Pcw</ci>
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<plus/>
<ci>Ru</ci>
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<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pc</ci>
<ci>Pl</ci>
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<ci>Pve</ci>
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<ci>Rs</ci>
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<cn cellml:units="dimensionless">0.001</cn>
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<eq/>
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<diff/>
<bvar>
<ci>time</ci>
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<ci>VA</ci>
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<times/>
<apply>
<minus/>
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<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pc</ci>
<ci>Pl</ci>
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<ci>Pve</ci>
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<ci>Rs</ci>
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<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Pstp</ci>
<ci>Tbody</ci>
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<apply>
<times/>
<apply>
<plus/>
<ci>PA</ci>
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<ci>Tstp</ci>
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<plus/>
<ci>O2flux</ci>
<ci>CO2flux</ci>
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<cn cellml:units="dimensionless">0.001</cn>
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<eq/>
<ci>dVAdt</ci>
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<times/>
<apply>
<minus/>
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<divide/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pc</ci>
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<ci>Pve</ci>
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<ci>Rs</ci>
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<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Pstp</ci>
<ci>Tbody</ci>
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<times/>
<apply>
<plus/>
<ci>PA</ci>
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<ci>Tstp</ci>
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<plus/>
<ci>O2flux</ci>
<ci>CO2flux</ci>
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<cn cellml:units="dimensionless">0.001</cn>
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<eq/>
<ci>PD</ci>
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<plus/>
<ci>Pc</ci>
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<times/>
<ci>Rc</ci>
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<plus/>
<ci>dVcdt</ci>
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<times/>
<apply>
<divide/>
<apply>
<minus/>
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<plus/>
<ci>Pc</ci>
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<ci>PA</ci>
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<ci>Rs</ci>
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<cn type="e-notation" cellml:units="dimensionless">1 <sep/>
3</cn>
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<eq/>
<ci>QdotDC</ci>
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<times/>
<apply>
<divide/>
<apply>
<minus/>
<ci>PD</ci>
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<plus/>
<ci>Pc</ci>
<ci>Ppl</ci>
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<ci>Rc</ci>
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<cn cellml:units="dimensionless">1000.0000000000001</cn>
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<eq/>
<ci>QdotED</ci>
<ci>QdotDC</ci>
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<eq/>
<ci>Pao_N2</ci>
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<minus/>
<apply>
<minus/>
<apply>
<minus/>
<ci>Pao</ci>
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<ci>Pao_O2</ci>
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<ci>Pao_CO2</ci>
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<eq/>
<ci>PplmmHg</ci>
<apply>
<times/>
<ci>Ppl</ci>
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<eq/>
<ci>PC_N2</ci>
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<times/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<plus/>
<ci>Pc</ci>
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<times/>
<ci>Pao</ci>
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<times/>
<ci>PC_O2</ci>
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<times/>
<ci>PC_CO2</ci>
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<cn cellml:units="dimensionless">0.7371913011426465</cn>
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<eq/>
<ci>PA_N2</ci>
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<times/>
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<minus/>
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<minus/>
<apply>
<plus/>
<ci>PA</ci>
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<times/>
<ci>Pao</ci>
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<times/>
<ci>PA_O2</ci>
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<times/>
<ci>PA_CO2</ci>
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</apply>
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<cn cellml:units="dimensionless">0.7371913011426465</cn>
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<eq/>
<ci>PD_N2</ci>
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<times/>
<apply>
<minus/>
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<minus/>
<apply>
<plus/>
<ci>PD</ci>
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<times/>
<ci>Pao</ci>
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<times/>
<ci>PD_O2</ci>
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<times/>
<ci>PD_CO2</ci>
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<cn cellml:units="dimensionless">0.7371913011426465</cn>
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<diff/>
<bvar>
<ci>time</ci>
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<ci>PO2_pc</ci>
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<times/>
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<divide/>
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<plus/>
<apply>
<times/>
<ci>Fpc</ci>
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<minus/>
<ci>CtO2_sc</ci>
<ci>CtO2_pc</ci>
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<ci>DL_O2</ci>
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<minus/>
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<ci>Vpc</ci>
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<plus/>
<ci>alphaO2</ci>
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<times/>
<ci>H</ci>
<ci>CHb</ci>
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<eq/>
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<diff/>
<bvar>
<ci>time</ci>
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<ci>PO2_sc</ci>
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<times/>
<apply>
<divide/>
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<plus/>
<apply>
<times/>
<ci>Fsc</ci>
<apply>
<minus/>
<ci>CtO2_pc</ci>
<ci>CtO2_sc</ci>
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<times/>
<ci>PS</ci>
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<minus/>
<ci>PO2_isf</ci>
<ci>PO2_sc</ci>
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<ci>Vsc</ci>
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<plus/>
<ci>alphaO2</ci>
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<times/>
<ci>H</ci>
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<diff/>
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<ci>time</ci>
</bvar>
<ci>PO2_isf</ci>
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<minus/>
<apply>
<divide/>
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<ci>PS</ci>
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<ci>PO2_isf</ci>
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<ci>Visf</ci>
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<apply>
<times/>
<apply>
<divide/>
<ci>V_O2</ci>
<apply>
<times/>
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</bvar>
<ci>PCO2_pc</ci>
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<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<ci>Fpc</ci>
<apply>
<minus/>
<ci>CtCO2_sc</ci>
<ci>CtCO2_pc</ci>
</apply>
</apply>
<apply>
<times/>
<ci>DL_CO2</ci>
<apply>
<minus/>
<ci>PA_CO2</ci>
<ci>PCO2_pc</ci>
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<cn cellml:units="dimensionless">0.0026785714285714286</cn>
</apply>
</apply>
<apply>
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<plus/>
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<ci>dSHbCO2dPCO2_pc</ci>
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<diff/>
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</bvar>
<ci>PCO2_sc</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<ci>Fsc</ci>
<apply>
<minus/>
<ci>CtCO2_pc</ci>
<ci>CtCO2_sc</ci>
</apply>
</apply>
<apply>
<times/>
<ci>PS</ci>
<ci>alphaCO2</ci>
<apply>
<minus/>
<ci>PCO2_isf</ci>
<ci>PCO2_sc</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">9.999999999999998 <sep/>
-4</cn>
</apply>
</apply>
<apply>
<times/>
<ci>Vsc</ci>
<apply>
<plus/>
<ci>alphaCO2</ci>
<apply>
<times/>
<ci>H</ci>
<ci>CHb</ci>
<ci>dSHbCO2dPCO2_sc</ci>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">0.01666666666666667</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PCO2_isf</ci>
</apply>
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<times/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>PS</ci>
<apply>
<minus/>
<ci>PCO2_sc</ci>
<ci>PCO2_isf</ci>
</apply>
</apply>
<ci>Visf</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>V_CO2</ci>
<apply>
<times/>
<ci>alphaCO2</ci>
<ci>Visf</ci>
</apply>
</apply>
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3</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.666666666666667 <sep/>
-5</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PD_O2</ci>
</apply>
<piecewise>
<piece>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotED</ci>
<ci>Pao_O2</ci>
</apply>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PD_O2</ci>
</apply>
</apply>
<ci>VD</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
<apply>
<gt/>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotED</ci>
<ci>PD_O2</ci>
</apply>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PC_O2</ci>
</apply>
</apply>
<ci>VD</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
</otherwise>
</piecewise>
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<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PC_O2</ci>
</apply>
<piecewise>
<piece>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PD_O2</ci>
</apply>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PC_O2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>PC_O2</ci>
<ci>dVcdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>Vc</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
<apply>
<gt/>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
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<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PC_O2</ci>
</apply>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PA_O2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>PC_O2</ci>
<ci>dVcdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>Vc</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PA_O2</ci>
</apply>
<piecewise>
<piece>
<apply>
<times/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PC_O2</ci>
</apply>
<apply>
<times/>
<ci>PA_O2</ci>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>VA</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Pstp</ci>
<ci>Tbody</ci>
</apply>
<ci>Tstp</ci>
</apply>
<ci>O2flux</ci>
</apply>
<ci>VA</ci>
</apply>
<cn cellml:units="dimensionless">0.01666666666666667</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
<apply>
<gt/>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
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<times/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PA_O2</ci>
</apply>
<apply>
<times/>
<ci>PA_O2</ci>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>VA</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Pstp</ci>
<ci>Tbody</ci>
</apply>
<ci>Tstp</ci>
</apply>
<ci>O2flux</ci>
</apply>
<ci>VA</ci>
</apply>
<cn cellml:units="dimensionless">0.01666666666666667</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PD_CO2</ci>
</apply>
<piecewise>
<piece>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotED</ci>
<ci>Pao_CO2</ci>
</apply>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PD_CO2</ci>
</apply>
</apply>
<ci>VD</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
<apply>
<gt/>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
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<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotED</ci>
<ci>PD_CO2</ci>
</apply>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PC_CO2</ci>
</apply>
</apply>
<ci>VD</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
</otherwise>
</piecewise>
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<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PC_CO2</ci>
</apply>
<piecewise>
<piece>
<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PD_CO2</ci>
</apply>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PC_CO2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>PC_CO2</ci>
<ci>dVcdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>Vc</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
<apply>
<gt/>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
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<apply>
<times/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotDC</ci>
<ci>PC_CO2</ci>
</apply>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PA_CO2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>PC_CO2</ci>
<ci>dVcdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>Vc</ci>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
</otherwise>
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<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>PA_CO2</ci>
</apply>
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<piece>
<apply>
<times/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PC_CO2</ci>
</apply>
<apply>
<times/>
<ci>PA_CO2</ci>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>VA</ci>
</apply>
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<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Pstp</ci>
<ci>Tbody</ci>
</apply>
<ci>Tstp</ci>
</apply>
<ci>CO2flux</ci>
</apply>
<ci>VA</ci>
</apply>
<cn cellml:units="dimensionless">0.01666666666666667</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
<apply>
<gt/>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">0</cn>
</apply>
</piece>
<otherwise>
<apply>
<times/>
<apply>
<minus/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<times/>
<ci>QdotCA</ci>
<ci>PA_CO2</ci>
</apply>
<apply>
<times/>
<ci>PA_CO2</ci>
<ci>dVAdt</ci>
<cn cellml:units="dimensionless">1000000.0000000001</cn>
</apply>
</apply>
<ci>VA</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Pstp</ci>
<ci>Tbody</ci>
</apply>
<ci>Tstp</ci>
</apply>
<ci>CO2flux</ci>
</apply>
<ci>VA</ci>
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<cn cellml:units="dimensionless">0.01666666666666667</cn>
</apply>
</apply>
<cn type="e-notation" cellml:units="dimensionless">1.0000000000000002 <sep/>
-6</cn>
</apply>
</otherwise>
</piecewise>
</apply>
</math>
</component>
<group>
<relationship_ref relationship="containment"/>
<component_ref component="SAmembrane">
<component_ref component="fast_sodium_current">
<component_ref component="fast_sodium_current_m_gate"/>
<component_ref component="fast_sodium_current_h_gate"/>
<component_ref component="fast_sodium_current_j_gate"/>
</component_ref>
<component_ref component="ACh_dependent_potassium_current">
<component_ref component="ACh_dependent_potassium_current_y_gate"/>
</component_ref>
<component_ref component="time_independent_potassium_current"/>
<component_ref component="transient_outward_K_current">
<component_ref component="transient_outward_K_current_oa_gate"/>
<component_ref component="transient_outward_K_current_oi_gate"/>
</component_ref>
<component_ref component="ultrarapid_delayed_rectifier_K_current">
<component_ref component="ultrarapid_delayed_rectifier_K_current_ua_gate"/>
<component_ref component="ultrarapid_delayed_rectifier_K_current_ui_gate"/>
</component_ref>
<component_ref component="rapid_delayed_rectifier_K_current">
<component_ref component="rapid_delayed_rectifier_K_current_xr_gate"/>
</component_ref>
<component_ref component="slow_delayed_rectifier_K_current">
<component_ref component="slow_delayed_rectifier_K_current_xs_gate"/>
</component_ref>
<component_ref component="T_type_Ca_channel">
<component_ref component="T_type_Ca_channel_d_gate"/>
<component_ref component="T_type_Ca_channel_f_gate"/>
</component_ref>
<component_ref component="L_type_Ca_channel">
<component_ref component="L_type_Ca_channel_d_gate"/>
<component_ref component="L_type_Ca_channel_f_gate"/>
<component_ref component="L_type_Ca_channel_f_Ca_gate"/>
</component_ref>
<component_ref component="sodium_potassium_pump"/>
<component_ref component="background_currents"/>
<component_ref component="Na_Ca_exchanger_current"/>
<component_ref component="sarcolemmal_calcium_pump_current"/>
<component_ref component="Ca_release_current_from_JSR">
<component_ref component="Ca_release_current_from_JSR_u_gate"/>
<component_ref component="Ca_release_current_from_JSR_v_gate"/>
<component_ref component="Ca_release_current_from_JSR_w_gate"/>
</component_ref>
<component_ref component="transfer_current_from_NSR_to_JSR"/>
<component_ref component="Ca_uptake_current_by_the_NSR"/>
<component_ref component="Ca_leak_current_by_the_NSR"/>
<component_ref component="Ca_buffers"/>
<component_ref component="intracellular_ion_concentrations"/>
<component_ref component="standard_ionic_concentrations"/>
</component_ref>
</group>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="fast_sodium_current">
<component_ref component="fast_sodium_current_m_gate"/>
<component_ref component="fast_sodium_current_h_gate"/>
<component_ref component="fast_sodium_current_j_gate"/>
</component_ref>
<component_ref component="transient_outward_K_current">
<component_ref component="transient_outward_K_current_oa_gate"/>
<component_ref component="transient_outward_K_current_oi_gate"/>
</component_ref>
<component_ref component="ultrarapid_delayed_rectifier_K_current">
<component_ref component="ultrarapid_delayed_rectifier_K_current_ua_gate"/>
<component_ref component="ultrarapid_delayed_rectifier_K_current_ui_gate"/>
</component_ref>
<component_ref component="rapid_delayed_rectifier_K_current">
<component_ref component="rapid_delayed_rectifier_K_current_xr_gate"/>
</component_ref>
<component_ref component="slow_delayed_rectifier_K_current">
<component_ref component="slow_delayed_rectifier_K_current_xs_gate"/>
</component_ref>
<component_ref component="T_type_Ca_channel">
<component_ref component="T_type_Ca_channel_d_gate"/>
<component_ref component="T_type_Ca_channel_f_gate"/>
</component_ref>
<component_ref component="L_type_Ca_channel">
<component_ref component="L_type_Ca_channel_d_gate"/>
<component_ref component="L_type_Ca_channel_f_gate"/>
<component_ref component="L_type_Ca_channel_f_Ca_gate"/>
</component_ref>
<component_ref component="ACh_dependent_potassium_current">
<component_ref component="ACh_dependent_potassium_current_y_gate"/>
</component_ref>
<component_ref component="Ca_release_current_from_JSR">
<component_ref component="Ca_release_current_from_JSR_u_gate"/>
<component_ref component="Ca_release_current_from_JSR_v_gate"/>
<component_ref component="Ca_release_current_from_JSR_w_gate"/>
</component_ref>
</group>
<connection>
<map_components component_1="additional_currents" component_2="Cai"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="LATiming" component_2="SAmembrane"/>
<map_variables variable_1="ISAin" variable_2="ISAout_atrium"/>
</connection>
<connection>
<map_components component_1="RATiming" component_2="SAmembrane"/>
<map_variables variable_1="ISAin" variable_2="ISAout_atrium"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="SAmembrane"/>
<map_variables variable_1="ISAstim" variable_2="ISAout"/>
</connection>
<connection>
<map_components component_1="ACh_dependent_potassium_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ACh_dependent_potassium_current" component_2="SAmembrane"/>
<map_variables variable_1="Vm" variable_2="V"/>
<map_variables variable_1="i_KACh" variable_2="i_KACh"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="ACh_dependent_potassium_current"/>
<map_variables variable_1="E_K" variable_2="E_K"/>
</connection>
<connection>
<map_components component_1="ACh_dependent_potassium_current" component_2="ACh_dependent_potassium_current_y_gate"/>
<map_variables variable_1="y" variable_2="y"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="Vm" variable_2="Vm"/>
</connection>
<connection>
<map_components component_1="funny_current" component_2="SAmembrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_f" variable_2="i_f"/>
</connection>
<connection>
<map_components component_1="funny_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="T_type_Ca_channel" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="T_type_Ca_channel" component_2="SAmembrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Ca_T" variable_2="i_Ca_T"/>
</connection>
<connection>
<map_components component_1="T_type_Ca_channel" component_2="T_type_Ca_channel_d_gate"/>
<map_variables variable_1="d_T" variable_2="d_T"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="T_type_Ca_channel" component_2="T_type_Ca_channel_f_gate"/>
<map_variables variable_1="f_T" variable_2="f_T"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="transient_outward_K_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="ultrarapid_delayed_rectifier_K_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="rapid_delayed_rectifier_K_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="slow_delayed_rectifier_K_current" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="L_type_Ca_channel" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Ca_release_current_from_JSR" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="transfer_current_from_NSR_to_JSR" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Ca_uptake_current_by_the_NSR" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Ca_leak_current_by_the_NSR" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Ca_buffers" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="intracellular_ion_concentrations" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="fast_sodium_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Na" variable_2="i_Na"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="time_independent_potassium_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_K1" variable_2="i_K1"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="transient_outward_K_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_to" variable_2="i_to"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="ultrarapid_delayed_rectifier_K_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Kur" variable_2="i_Kur"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="rapid_delayed_rectifier_K_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Kr" variable_2="i_Kr"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="slow_delayed_rectifier_K_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Ks" variable_2="i_Ks"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="L_type_Ca_channel"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_Ca_L" variable_2="i_Ca_L"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="sodium_potassium_pump"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_NaK" variable_2="i_NaK"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="background_currents"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_B_Ca" variable_2="i_B_Ca"/>
<map_variables variable_1="i_B_Na" variable_2="i_B_Na"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="Na_Ca_exchanger_current"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="i_NaCa" variable_2="i_NaCa"/>
<map_variables variable_1="R" variable_2="R"/>
<map_variables variable_1="T" variable_2="T"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="sarcolemmal_calcium_pump_current"/>
<map_variables variable_1="i_CaP" variable_2="i_CaP"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="Ca_release_current_from_JSR" component_2="SAmembrane"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="SAmembrane" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_Na" variable_2="i_Na"/>
<map_variables variable_1="Na_i" variable_2="Na_i"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="standard_ionic_concentrations"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="background_currents"/>
<map_variables variable_1="E_Na" variable_2="E_Na"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_K1" variable_2="i_K1"/>
<map_variables variable_1="K_i" variable_2="K_i"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="standard_ionic_concentrations"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="transient_outward_K_current"/>
<map_variables variable_1="E_K" variable_2="E_K"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="background_currents"/>
<map_variables variable_1="E_K" variable_2="E_K"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="ultrarapid_delayed_rectifier_K_current"/>
<map_variables variable_1="E_K" variable_2="E_K"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="rapid_delayed_rectifier_K_current"/>
<map_variables variable_1="E_K" variable_2="E_K"/>
</connection>
<connection>
<map_components component_1="time_independent_potassium_current" component_2="slow_delayed_rectifier_K_current"/>
<map_variables variable_1="E_K" variable_2="E_K"/>
</connection>
<connection>
<map_components component_1="ultrarapid_delayed_rectifier_K_current" component_2="transient_outward_K_current"/>
<map_variables variable_1="K_Q10" variable_2="K_Q10"/>
</connection>
<connection>
<map_components component_1="ultrarapid_delayed_rectifier_K_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_Kur" variable_2="i_Kur"/>
</connection>
<connection>
<map_components component_1="rapid_delayed_rectifier_K_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_Kr" variable_2="i_Kr"/>
</connection>
<connection>
<map_components component_1="slow_delayed_rectifier_K_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_Ks" variable_2="i_Ks"/>
</connection>
<connection>
<map_components component_1="intracellular_ion_concentrations" component_2="transient_outward_K_current"/>
<map_variables variable_1="i_to" variable_2="i_to"/>
</connection>
<connection>
<map_components component_1="L_type_Ca_channel" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="i_Ca_L" variable_2="i_Ca_L"/>
</connection>
<connection>
<map_components component_1="L_type_Ca_channel" component_2="Ca_release_current_from_JSR"/>
<map_variables variable_1="i_Ca_L" variable_2="i_Ca_L"/>
</connection>
<connection>
<map_components component_1="sodium_potassium_pump" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="Na_i" variable_2="Na_i"/>
<map_variables variable_1="i_NaK" variable_2="i_NaK"/>
</connection>
<connection>
<map_components component_1="sodium_potassium_pump" component_2="standard_ionic_concentrations"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
</connection>
<connection>
<map_components component_1="background_currents" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="i_B_Ca" variable_2="i_B_Ca"/>
<map_variables variable_1="i_B_Na" variable_2="i_B_Na"/>
<map_variables variable_1="i_B_K" variable_2="i_B_K"/>
</connection>
<connection>
<map_components component_1="background_currents" component_2="standard_ionic_concentrations"/>
<map_variables variable_1="Ca_o" variable_2="Ca_o"/>
</connection>
<connection>
<map_components component_1="Na_Ca_exchanger_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="Na_i" variable_2="Na_i"/>
<map_variables variable_1="i_NaCa" variable_2="i_NaCa"/>
</connection>
<connection>
<map_components component_1="Na_Ca_exchanger_current" component_2="standard_ionic_concentrations"/>
<map_variables variable_1="Ca_o" variable_2="Ca_o"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="Na_Ca_exchanger_current" component_2="Ca_release_current_from_JSR"/>
<map_variables variable_1="i_NaCa" variable_2="i_NaCa"/>
</connection>
<connection>
<map_components component_1="sarcolemmal_calcium_pump_current" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_CaP" variable_2="i_CaP"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
</connection>
<connection>
<map_components component_1="intracellular_ion_concentrations" component_2="Ca_release_current_from_JSR"/>
<map_variables variable_1="i_rel" variable_2="i_rel"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="Ca_rel" variable_2="Ca_rel"/>
<map_variables variable_1="V_rel" variable_2="V_rel"/>
</connection>
<connection>
<map_components component_1="intracellular_ion_concentrations" component_2="transfer_current_from_NSR_to_JSR"/>
<map_variables variable_1="i_tr" variable_2="i_tr"/>
<map_variables variable_1="Ca_up" variable_2="Ca_up"/>
<map_variables variable_1="Ca_rel" variable_2="Ca_rel"/>
</connection>
<connection>
<map_components component_1="intracellular_ion_concentrations" component_2="Ca_uptake_current_by_the_NSR"/>
<map_variables variable_1="i_up" variable_2="i_up"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
</connection>
<connection>
<map_components component_1="Ca_leak_current_by_the_NSR" component_2="Ca_uptake_current_by_the_NSR"/>
<map_variables variable_1="I_up_max" variable_2="I_up_max"/>
</connection>
<connection>
<map_components component_1="Ca_leak_current_by_the_NSR" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="i_up_leak" variable_2="i_up_leak"/>
<map_variables variable_1="Ca_up" variable_2="Ca_up"/>
</connection>
<connection>
<map_components component_1="Ca_buffers" component_2="intracellular_ion_concentrations"/>
<map_variables variable_1="CMDN_max" variable_2="CMDN_max"/>
<map_variables variable_1="CSQN_max" variable_2="CSQN_max"/>
<map_variables variable_1="TRPN_max" variable_2="TRPN_max"/>
<map_variables variable_1="Km_CMDN" variable_2="Km_CMDN"/>
<map_variables variable_1="Km_CSQN" variable_2="Km_CSQN"/>
<map_variables variable_1="Km_TRPN" variable_2="Km_TRPN"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="Ca_rel" variable_2="Ca_rel"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="fast_sodium_current_m_gate"/>
<map_variables variable_1="m" variable_2="m"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="fast_sodium_current_h_gate"/>
<map_variables variable_1="h" variable_2="h"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="fast_sodium_current" component_2="fast_sodium_current_j_gate"/>
<map_variables variable_1="j" variable_2="j"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="L_type_Ca_channel" component_2="L_type_Ca_channel_d_gate"/>
<map_variables variable_1="d" variable_2="d"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="L_type_Ca_channel" component_2="L_type_Ca_channel_f_gate"/>
<map_variables variable_1="f" variable_2="f"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="L_type_Ca_channel" component_2="L_type_Ca_channel_f_Ca_gate"/>
<map_variables variable_1="f_Ca" variable_2="f_Ca"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
</connection>
<connection>
<map_components component_1="transient_outward_K_current" component_2="transient_outward_K_current_oa_gate"/>
<map_variables variable_1="oa" variable_2="oa"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="K_Q10" variable_2="K_Q10"/>
</connection>
<connection>
<map_components component_1="transient_outward_K_current" component_2="transient_outward_K_current_oi_gate"/>
<map_variables variable_1="oi" variable_2="oi"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="K_Q10" variable_2="K_Q10"/>
</connection>
<connection>
<map_components component_1="ultrarapid_delayed_rectifier_K_current" component_2="ultrarapid_delayed_rectifier_K_current_ua_gate"/>
<map_variables variable_1="ua" variable_2="ua"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="K_Q10" variable_2="K_Q10"/>
</connection>
<connection>
<map_components component_1="ultrarapid_delayed_rectifier_K_current" component_2="ultrarapid_delayed_rectifier_K_current_ui_gate"/>
<map_variables variable_1="ui" variable_2="ui"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="K_Q10" variable_2="K_Q10"/>
</connection>
<connection>
<map_components component_1="rapid_delayed_rectifier_K_current" component_2="rapid_delayed_rectifier_K_current_xr_gate"/>
<map_variables variable_1="xr" variable_2="xr"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="slow_delayed_rectifier_K_current" component_2="slow_delayed_rectifier_K_current_xs_gate"/>
<map_variables variable_1="xs" variable_2="xs"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="Ca_release_current_from_JSR" component_2="Ca_release_current_from_JSR_u_gate"/>
<map_variables variable_1="u" variable_2="u"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="Fn" variable_2="Fn"/>
</connection>
<connection>
<map_components component_1="Ca_release_current_from_JSR" component_2="Ca_release_current_from_JSR_v_gate"/>
<map_variables variable_1="v" variable_2="v"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
<map_variables variable_1="Fn" variable_2="Fn"/>
</connection>
<connection>
<map_components component_1="Ca_release_current_from_JSR" component_2="Ca_release_current_from_JSR_w_gate"/>
<map_variables variable_1="w" variable_2="w"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="LeftVentricle" component_2="NL_model"/>
<map_variables variable_1="P_LVin" variable_2="P_LV"/>
<map_variables variable_1="V_LV" variable_2="V_LV"/>
</connection>
<connection>
<map_components component_1="RightVentricle" component_2="NL_model"/>
<map_variables variable_1="P_LV" variable_2="P_LV"/>
</connection>
<connection>
<map_components component_1="RightVentricle" component_2="LeftVentricle"/>
<map_variables variable_1="V_LV" variable_2="V_LV"/>
</connection>
<connection>
<map_components component_1="GutIntestine" component_2="Liver"/>
<map_variables variable_1="F_GIV" variable_2="F_GIV"/>
<map_variables variable_1="conc_X_GI" variable_2="conc_X_GI"/>
<map_variables variable_1="P_LI" variable_2="P_LI"/>
</connection>
<connection>
<map_components component_1="Skin" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Skin" component_2="Arteries"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_SK" variable_2="F_SK"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Skin" component_2="Veins"/>
<map_variables variable_1="P_VE" variable_2="P_VE"/>
<map_variables variable_1="F_SKV" variable_2="F_SKV"/>
<map_variables variable_1="conc_X_SK" variable_2="conc_X_SK"/>
</connection>
<connection>
<map_components component_1="LeftAtrium" component_2="PulmonaryVein"/>
<map_variables variable_1="P_PV" variable_2="P_PV"/>
<map_variables variable_1="F_LA" variable_2="F_LA"/>
<map_variables variable_1="conc_X_PV" variable_2="conc_X_PV"/>
</connection>
<connection>
<map_components component_1="LeftAtrium" component_2="LeftVentricle"/>
<map_variables variable_1="F_LV" variable_2="F_LV"/>
<map_variables variable_1="P_LA" variable_2="P_LA"/>
<map_variables variable_1="conc_X_LA" variable_2="conc_X_LA"/>
</connection>
<connection>
<map_components component_1="LeftVentricle" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Aorta" component_2="NL_model"/>
<map_variables variable_1="P_LV" variable_2="P_LV"/>
</connection>
<connection>
<map_components component_1="LeftVentricle" component_2="Aorta"/>
<map_variables variable_1="F_AO" variable_2="F_AO"/>
<map_variables variable_1="conc_X_LV" variable_2="conc_X_LV"/>
</connection>
<connection>
<map_components component_1="CoronaryCirc" component_2="NL_model"/>
<map_variables variable_1="P_LV" variable_2="P_LV"/>
</connection>
<connection>
<map_components component_1="LeftVentricle" component_2="CoronaryCirc"/>
<map_variables variable_1="F_CO" variable_2="F_CO"/>
<map_variables variable_1="conc_X_LV" variable_2="conc_X_LV"/>
</connection>
<connection>
<map_components component_1="Aorta" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Aorta" component_2="Arteries"/>
<map_variables variable_1="F_AR" variable_2="F_AR"/>
<map_variables variable_1="P_AO" variable_2="P_AO"/>
<map_variables variable_1="conc_X_AO" variable_2="conc_X_AO"/>
</connection>
<connection>
<map_components component_1="Aorta" component_2="CarotidCirc"/>
<map_variables variable_1="F_CR" variable_2="F_CR"/>
<map_variables variable_1="P_AO" variable_2="P_AO"/>
<map_variables variable_1="conc_X_AO" variable_2="conc_X_AO"/>
</connection>
<connection>
<map_components component_1="CoronaryCirc" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="CoronaryCirc" component_2="RightAtrium"/>
<map_variables variable_1="P_RA" variable_2="P_RA"/>
<map_variables variable_1="F_COV" variable_2="F_COV"/>
<map_variables variable_1="conc_X_CO" variable_2="conc_X_CO"/>
</connection>
<connection>
<map_components component_1="CarotidCirc" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="CarotidCirc" component_2="VenaCava"/>
<map_variables variable_1="P_VC" variable_2="P_VC"/>
<map_variables variable_1="F_CRV" variable_2="F_CRV"/>
<map_variables variable_1="conc_X_CR" variable_2="conc_X_CR"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="Adipose"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_AD" variable_2="F_AD"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="Muscle"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_MU" variable_2="F_MU"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="GutIntestine"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_GI" variable_2="F_GI"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="Liver"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_LI" variable_2="F_LI"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="Kidney"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_KI" variable_2="F_KI"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Arteries" component_2="OtherTissue"/>
<map_variables variable_1="P_AR" variable_2="P_AR"/>
<map_variables variable_1="F_OT" variable_2="F_OT"/>
<map_variables variable_1="conc_X_AR" variable_2="conc_X_AR"/>
</connection>
<connection>
<map_components component_1="Adipose" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Adipose" component_2="Veins"/>
<map_variables variable_1="P_VE" variable_2="P_VE"/>
<map_variables variable_1="F_ADV" variable_2="F_ADV"/>
<map_variables variable_1="conc_X_AD" variable_2="conc_X_AD"/>
</connection>
<connection>
<map_components component_1="Muscle" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Muscle" component_2="Veins"/>
<map_variables variable_1="P_VE" variable_2="P_VE"/>
<map_variables variable_1="F_MUV" variable_2="F_MUV"/>
<map_variables variable_1="conc_X_MU" variable_2="conc_X_MU"/>
</connection>
<connection>
<map_components component_1="GutIntestine" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Liver" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Liver" component_2="Veins"/>
<map_variables variable_1="P_VE" variable_2="P_VE"/>
<map_variables variable_1="F_LIV" variable_2="F_LIV"/>
<map_variables variable_1="conc_X_LI" variable_2="conc_X_LI"/>
</connection>
<connection>
<map_components component_1="Kidney" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Kidney" component_2="Veins"/>
<map_variables variable_1="P_VE" variable_2="P_VE"/>
<map_variables variable_1="F_KIV" variable_2="F_KIV"/>
<map_variables variable_1="conc_X_KI" variable_2="conc_X_KI"/>
</connection>
<connection>
<map_components component_1="OtherTissue" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="OtherTissue" component_2="Veins"/>
<map_variables variable_1="P_VE" variable_2="P_VE"/>
<map_variables variable_1="F_OTV" variable_2="F_OTV"/>
<map_variables variable_1="conc_X_OT" variable_2="conc_X_OT"/>
</connection>
<connection>
<map_components component_1="Veins" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Veins" component_2="VenaCava"/>
<map_variables variable_1="P_VC" variable_2="P_VC"/>
<map_variables variable_1="F_VEV" variable_2="F_VEV"/>
<map_variables variable_1="conc_X_VE" variable_2="conc_X_VE"/>
</connection>
<connection>
<map_components component_1="VenaCava" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="VenaCava" component_2="RightAtrium"/>
<map_variables variable_1="P_RA" variable_2="P_RA"/>
<map_variables variable_1="F_VCV" variable_2="F_VCV"/>
<map_variables variable_1="conc_X_VC" variable_2="conc_X_VC"/>
</connection>
<connection>
<map_components component_1="RATiming" component_2="environment"/>
<map_variables variable_1="realtime" variable_2="time"/>
<map_variables variable_1="HR" variable_2="HR"/>
<map_variables variable_1="hrf" variable_2="hrf"/>
</connection>
<connection>
<map_components component_1="RAElastanceFunction" component_2="environment"/>
<map_variables variable_1="hrf" variable_2="hrf"/>
</connection>
<connection>
<map_components component_1="RATiming" component_2="RAElastanceFunction"/>
<map_variables variable_1="beattime" variable_2="time"/>
</connection>
<connection>
<map_components component_1="RightAtrium" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="RAElastanceFunction" component_2="RightAtrium"/>
<map_variables variable_1="E_RA" variable_2="E_RA"/>
</connection>
<connection>
<map_components component_1="RightAtrium" component_2="RightVentricle"/>
<map_variables variable_1="F_RV" variable_2="F_RV"/>
<map_variables variable_1="P_RA" variable_2="P_RA"/>
<map_variables variable_1="conc_X_RA" variable_2="conc_X_RA"/>
</connection>
<connection>
<map_components component_1="RightVentricle" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="RightVentricle" component_2="PulmonaryArtery"/>
<map_variables variable_1="F_PA" variable_2="F_PA"/>
<map_variables variable_1="P_RV" variable_2="P_RV"/>
<map_variables variable_1="conc_X_RV" variable_2="conc_X_RV"/>
</connection>
<connection>
<map_components component_1="PulmonaryArtery" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PulmonaryArteries" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PulmonaryArteries" component_2="PulmonaryCapillaries"/>
<map_variables variable_1="F_PC" variable_2="F_PC"/>
<map_variables variable_1="P_Pa" variable_2="P_Pa"/>
<map_variables variable_1="conc_X_Pa" variable_2="conc_X_Pa"/>
</connection>
<connection>
<map_components component_1="PulmonaryArteries" component_2="Shunt"/>
<map_variables variable_1="F_SH" variable_2="F_SH"/>
<map_variables variable_1="P_Pa" variable_2="P_Pa"/>
</connection>
<connection>
<map_components component_1="PulmonaryArteries" component_2="PulmonaryArtery"/>
<map_variables variable_1="P_PA" variable_2="P_PA"/>
<map_variables variable_1="F_Pa" variable_2="F_Pa"/>
<map_variables variable_1="conc_X_PA" variable_2="conc_X_PA"/>
</connection>
<connection>
<map_components component_1="Shunt" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Shunt" component_2="PulmonaryCapillaries"/>
<map_variables variable_1="P_PC" variable_2="P_PC"/>
</connection>
<connection>
<map_components component_1="Shunt" component_2="PulmonaryVein"/>
<map_variables variable_1="F_SH" variable_2="F_SH"/>
</connection>
<connection>
<map_components component_1="PulmonaryCapillaries" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PulmonaryCapillaries" component_2="PulmonaryVein"/>
<map_variables variable_1="P_PV" variable_2="P_PV"/>
<map_variables variable_1="F_PCV" variable_2="F_PCV"/>
<map_variables variable_1="conc_X_PC" variable_2="conc_X_PC"/>
</connection>
<connection>
<map_components component_1="PulmonaryVein" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="PulmonaryVein" component_2="PulmonaryArteries"/>
<map_variables variable_1="conc_X_Pa" variable_2="conc_X_Pa"/>
</connection>
<connection>
<map_components component_1="LATiming" component_2="environment"/>
<map_variables variable_1="realtime" variable_2="time"/>
<map_variables variable_1="HR" variable_2="HR"/>
<map_variables variable_1="hrf" variable_2="hrf"/>
</connection>
<connection>
<map_components component_1="LAElastanceFunction" component_2="environment"/>
<map_variables variable_1="hrf" variable_2="hrf"/>
</connection>
<connection>
<map_components component_1="LAElastanceFunction" component_2="LATiming"/>
<map_variables variable_1="time" variable_2="beattime"/>
</connection>
<connection>
<map_components component_1="LAElastanceFunction" component_2="LeftAtrium"/>
<map_variables variable_1="E_LA" variable_2="E_LA"/>
</connection>
<connection>
<map_components component_1="LeftAtrium" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="NL_model" component_2="Cai"/>
<map_variables variable_1="Cai_in" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="NL_model" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="K1_gate" component_2="EK"/>
<map_variables variable_1="E_K" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="r_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="s_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="Xr1_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="Xr2_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="Xs_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="d_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="f_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="fCa_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="g_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="g_gate" component_2="Cai"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="g_gate" component_2="default_parameters"/>
<map_variables variable_1="tau_g" variable_2="tau_g"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="membrane_potential"/>
<map_variables variable_1="Cm" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="additional_currents"/>
<map_variables variable_1="ICa_additional" variable_2="ICa_additional"/>
<map_variables variable_1="INa_additional" variable_2="INa_additional"/>
<map_variables variable_1="IK_additional" variable_2="IK_additional"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="K_flux"/>
<map_variables variable_1="vC" variable_2="vC"/>
<map_variables variable_1="Am" variable_2="Am"/>
</connection>
<connection>
<map_components component_1="additional_currents" component_2="K_flux"/>
<map_variables variable_1="IK_additional" variable_2="IK_additional"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="Na_flux"/>
<map_variables variable_1="vC" variable_2="vC"/>
<map_variables variable_1="Am" variable_2="Am"/>
</connection>
<connection>
<map_components component_1="additional_currents" component_2="Na_flux"/>
<map_variables variable_1="INa_additional" variable_2="INa_additional"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="Ca_flux"/>
<map_variables variable_1="vC" variable_2="vC"/>
<map_variables variable_1="Am" variable_2="Am"/>
</connection>
<connection>
<map_components component_1="additional_currents" component_2="Ca_flux"/>
<map_variables variable_1="ICa_additional" variable_2="ICa_additional"/>
</connection>
<connection>
<map_components component_1="Ca_SR_flux" component_2="additional_currents"/>
<map_variables variable_1="JCaSR_additional" variable_2="JCaSR_additional"/>
</connection>
<connection>
<map_components component_1="INa" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="INa"/>
<map_variables variable_1="g_Na" variable_2="g_Na"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="default_parameters"/>
<map_variables variable_1="g_K1" variable_2="g_K1"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="Ito"/>
<map_variables variable_1="g_to" variable_2="g_to"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="IKr"/>
<map_variables variable_1="g_Kr" variable_2="g_Kr"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="IKs"/>
<map_variables variable_1="g_Ks" variable_2="g_Ks"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="INaK"/>
<map_variables variable_1="P_NaK" variable_2="P_NaK"/>
<map_variables variable_1="K_mNa" variable_2="K_mNa"/>
<map_variables variable_1="K_mK" variable_2="K_mK"/>
<map_variables variable_1="temperature" variable_2="T"/>
<map_variables variable_1="Ko" variable_2="Ko"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="IpK"/>
<map_variables variable_1="g_pK" variable_2="g_pK"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="IbNa"/>
<map_variables variable_1="g_bNa" variable_2="g_bNa"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="ICaL"/>
<map_variables variable_1="g_CaL" variable_2="g_CaL"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
<map_variables variable_1="temperature" variable_2="T"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="IpCa"/>
<map_variables variable_1="g_pCa" variable_2="g_pCa"/>
<map_variables variable_1="K_pCa" variable_2="K_pCa"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="INaCa"/>
<map_variables variable_1="k_NaCa" variable_2="k_NaCa"/>
<map_variables variable_1="K_mNai" variable_2="K_mNai"/>
<map_variables variable_1="K_mCa" variable_2="K_mCa"/>
<map_variables variable_1="k_sat" variable_2="k_sat"/>
<map_variables variable_1="gamma" variable_2="gamma"/>
<map_variables variable_1="alpha" variable_2="alpha"/>
<map_variables variable_1="temperature" variable_2="T"/>
<map_variables variable_1="Nao" variable_2="Nao"/>
<map_variables variable_1="Cao" variable_2="Cao"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="IbCa"/>
<map_variables variable_1="g_bCa" variable_2="g_bCa"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="ENa"/>
<map_variables variable_1="temperature" variable_2="T"/>
<map_variables variable_1="Nao" variable_2="extracellular_concentration"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="EK"/>
<map_variables variable_1="temperature" variable_2="T"/>
<map_variables variable_1="Ko" variable_2="extracellular_concentration"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="ECa"/>
<map_variables variable_1="temperature" variable_2="T"/>
<map_variables variable_1="Cao" variable_2="extracellular_concentration"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="EKs"/>
<map_variables variable_1="temperature" variable_2="T"/>
<map_variables variable_1="Ko" variable_2="extracellular_concentration_1"/>
<map_variables variable_1="Nao" variable_2="extracellular_concentration_2"/>
<map_variables variable_1="p_KNa" variable_2="multiplier_2"/>
</connection>
<connection>
<map_components component_1="environment" component_2="Nai"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="environment" component_2="Ki"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="default_parameters"/>
<map_variables variable_1="Bufc" variable_2="Bufc"/>
<map_variables variable_1="Kbufc" variable_2="Kbufc"/>
<map_variables variable_1="Bufsr" variable_2="Bufsr"/>
<map_variables variable_1="Kbufsr" variable_2="Kbufsr"/>
<map_variables variable_1="vSR" variable_2="vSR"/>
<map_variables variable_1="vC" variable_2="vC"/>
<map_variables variable_1="Am" variable_2="Am"/>
<map_variables variable_1="Capacitance" variable_2="Cm"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Jleak" component_2="default_parameters"/>
<map_variables variable_1="V_leak" variable_2="V_leak"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="Jup"/>
<map_variables variable_1="Vmax_up" variable_2="Vmax_up"/>
<map_variables variable_1="K_up" variable_2="K_up"/>
</connection>
<connection>
<map_components component_1="default_parameters" component_2="Jrel"/>
<map_variables variable_1="a_rel" variable_2="a_rel"/>
<map_variables variable_1="b_rel" variable_2="b_rel"/>
<map_variables variable_1="c_rel" variable_2="c_rel"/>
<map_variables variable_1="tau_g" variable_2="tau_g"/>
</connection>
<connection>
<map_components component_1="Jrel" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="m_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="m_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="h_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="h_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="j_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="j_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="K1_gate" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="r_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="s_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Xr1_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Xr2_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="Xs_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="d_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="f_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="fCa_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="g_gate" component_2="environment"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="default_initial_conditions"/>
<map_variables variable_1="V_initial" variable_2="V_initial"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="total_membrane_current"/>
<map_variables variable_1="Itotal" variable_2="Itotal"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="INa"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="IK1"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="IKr"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="IKs"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="INaK"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="IpK"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="IbNa"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="ICaL"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="INaCa"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="IbCa"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="membrane_potential" component_2="Jrel"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="INa"/>
<map_variables variable_1="INa" variable_2="INa"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IK1"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="Ito"/>
<map_variables variable_1="Ito" variable_2="Ito"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IKr"/>
<map_variables variable_1="IKr" variable_2="IKr"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IKs"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="INaK"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IpK"/>
<map_variables variable_1="IpK" variable_2="IpK"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IbNa"/>
<map_variables variable_1="IbNa" variable_2="IbNa"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="ICaL"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IpCa"/>
<map_variables variable_1="IpCa" variable_2="IpCa"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="INaCa"/>
<map_variables variable_1="INaCa" variable_2="INaCa"/>
</connection>
<connection>
<map_components component_1="total_membrane_current" component_2="IbCa"/>
<map_variables variable_1="IbCa" variable_2="IbCa"/>
</connection>
<connection>
<map_components component_1="INa" component_2="ENa"/>
<map_variables variable_1="E_Na" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="INaK" component_2="ENa"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="R" variable_2="R"/>
</connection>
<connection>
<map_components component_1="IbNa" component_2="ENa"/>
<map_variables variable_1="E_Na" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="INaCa" component_2="ENa"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="R" variable_2="R"/>
</connection>
<connection>
<map_components component_1="ENa" component_2="Nai"/>
<map_variables variable_1="intracellular_concentration" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="ENa" component_2="Na_flux"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="Na_flux"/>
<map_variables variable_1="Na_flux" variable_2="Na_flux"/>
</connection>
<connection>
<map_components component_1="Na_flux" component_2="INa"/>
<map_variables variable_1="INa" variable_2="INa"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INaK"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Na_flux" component_2="INaK"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="Na_flux" component_2="IbNa"/>
<map_variables variable_1="IbNa" variable_2="IbNa"/>
</connection>
<connection>
<map_components component_1="Nai" component_2="INaCa"/>
<map_variables variable_1="Nai" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Na_flux" component_2="INaCa"/>
<map_variables variable_1="INaCa" variable_2="INaCa"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="EK"/>
<map_variables variable_1="E_K" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="EK"/>
<map_variables variable_1="E_K" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="EKs"/>
<map_variables variable_1="E_Ks" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="IpK" component_2="EK"/>
<map_variables variable_1="E_K" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="EK" component_2="Ki"/>
<map_variables variable_1="intracellular_concentration" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="EK" component_2="K_flux"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="EKs" component_2="Ki"/>
<map_variables variable_1="intracellular_concentration_1" variable_2="Ki"/>
</connection>
<connection>
<map_components component_1="EKs" component_2="Nai"/>
<map_variables variable_1="intracellular_concentration_2" variable_2="Nai"/>
</connection>
<connection>
<map_components component_1="Ki" component_2="K_flux"/>
<map_variables variable_1="K_flux" variable_2="K_flux"/>
</connection>
<connection>
<map_components component_1="K_flux" component_2="IK1"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="K_flux" component_2="Ito"/>
<map_variables variable_1="Ito" variable_2="Ito"/>
</connection>
<connection>
<map_components component_1="K_flux" component_2="IKr"/>
<map_variables variable_1="IKr" variable_2="IKr"/>
</connection>
<connection>
<map_components component_1="K_flux" component_2="IKs"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
</connection>
<connection>
<map_components component_1="K_flux" component_2="IpK"/>
<map_variables variable_1="IpK" variable_2="IpK"/>
</connection>
<connection>
<map_components component_1="K_flux" component_2="INaK"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="ECa"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="R" variable_2="R"/>
</connection>
<connection>
<map_components component_1="IbCa" component_2="ECa"/>
<map_variables variable_1="E_Ca" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="ECa" component_2="Cai"/>
<map_variables variable_1="intracellular_concentration" variable_2="Cai"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="ECa" component_2="Ca_flux"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="Ca_flux" component_2="Cai"/>
<map_variables variable_1="Ca_flux" variable_2="Ca_flux"/>
</connection>
<connection>
<map_components component_1="Ca_SR_flux" component_2="Cai"/>
<map_variables variable_1="Ca_SR_flux" variable_2="Ca_SR_flux"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="IpCa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="INaCa"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="Jleak"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
<map_variables variable_1="CaSR" variable_2="CaSR"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="Jup"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="Cai" component_2="Jrel"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
<map_variables variable_1="CaSR" variable_2="CaSR"/>
</connection>
<connection>
<map_components component_1="Jrel" component_2="d_gate"/>
<map_variables variable_1="d" variable_2="d"/>
</connection>
<connection>
<map_components component_1="Ca_flux" component_2="ICaL"/>
<map_variables variable_1="ICaL" variable_2="ICaL"/>
</connection>
<connection>
<map_components component_1="Ca_flux" component_2="IpCa"/>
<map_variables variable_1="IpCa" variable_2="IpCa"/>
</connection>
<connection>
<map_components component_1="Ca_flux" component_2="INaCa"/>
<map_variables variable_1="INaCa" variable_2="INaCa"/>
</connection>
<connection>
<map_components component_1="Ca_flux" component_2="IbCa"/>
<map_variables variable_1="IbCa" variable_2="IbCa"/>
</connection>
<connection>
<map_components component_1="Ca_SR_flux" component_2="Jleak"/>
<map_variables variable_1="Jleak" variable_2="Jleak"/>
</connection>
<connection>
<map_components component_1="Ca_SR_flux" component_2="Jup"/>
<map_variables variable_1="Jup" variable_2="Jup"/>
</connection>
<connection>
<map_components component_1="Ca_SR_flux" component_2="Jrel"/>
<map_variables variable_1="Jrel" variable_2="Jrel"/>
</connection>
<connection>
<map_components component_1="INa" component_2="m_gate"/>
<map_variables variable_1="m" variable_2="m"/>
</connection>
<connection>
<map_components component_1="INa" component_2="h_gate"/>
<map_variables variable_1="h" variable_2="h"/>
</connection>
<connection>
<map_components component_1="INa" component_2="j_gate"/>
<map_variables variable_1="j" variable_2="j"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="K1_gate"/>
<map_variables variable_1="K1_infinity" variable_2="K1_infinity"/>
</connection>
<connection>
<map_components component_1="IK1" component_2="EK"/>
<map_variables variable_1="E_K" variable_2="reversal_potential"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="r_gate"/>
<map_variables variable_1="r" variable_2="r"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="membrane_potential"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="Ito" component_2="s_gate"/>
<map_variables variable_1="s" variable_2="s"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="Xr1_gate"/>
<map_variables variable_1="Xr1" variable_2="Xr1"/>
</connection>
<connection>
<map_components component_1="IKr" component_2="Xr2_gate"/>
<map_variables variable_1="Xr2" variable_2="Xr2"/>
</connection>
<connection>
<map_components component_1="IKs" component_2="Xs_gate"/>
<map_variables variable_1="Xs" variable_2="Xs"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="d_gate"/>
<map_variables variable_1="d" variable_2="d"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="f_gate"/>
<map_variables variable_1="f" variable_2="f"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="Cai"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="fCa_gate" component_2="Cai"/>
<map_variables variable_1="Cai" variable_2="Cai"/>
</connection>
<connection>
<map_components component_1="ICaL" component_2="fCa_gate"/>
<map_variables variable_1="fCa" variable_2="fCa"/>
</connection>
<connection>
<map_components component_1="Jrel" component_2="g_gate"/>
<map_variables variable_1="g" variable_2="g"/>
</connection>
<connection>
<map_components component_1="Muscle" component_2="lung"/>
<map_variables variable_1="V_MU" variable_2="V_MU"/>
<map_variables variable_1="F_MU" variable_2="F_MU"/>
</connection>
<connection>
<map_components component_1="lung" component_2="PulmonaryCapillaries"/>
<map_variables variable_1="F_PC" variable_2="F_PC"/>
<map_variables variable_1="V_PC" variable_2="V_PC"/>
</connection>
<connection>
<map_components component_1="environment" component_2="lung"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">
<rdf:Description rdf:about="">
<dc:creator rdf:parseType="Resource">
<vCard:N rdf:parseType="Resource">
<vCard:Family>Cumin</vCard:Family>
<vCard:Given>David</vCard:Given>
</vCard:N>
<vCard:EMAIL rdf:parseType="Resource">
<rdf:value>d.cumin@auckland.ac.nz</rdf:value>
<rdf:type rdf:resource="http://imc.org/vCard/3.0#internet"/>
</vCard:EMAIL>
<vCard:ORG rdf:parseType="Resource">
<vCard:Orgname>The University of Auckland</vCard:Orgname>
<vCard:Orgunit>Auckland Bioengineering Institute</vCard:Orgunit>
</vCard:ORG>
</dc:creator>
<dcterms:created rdf:parseType="Resource">
<dcterms:W3CDTF>2010-10-06</dcterms:W3CDTF>
</dcterms:created>
</rdf:Description>
<rdf:Description rdf:about="#FINAL">
<bqs:reference rdf:parseType="Resource">
<dc:subject rdf:parseType="Resource">
<bqs:subject_type>keyword</bqs:subject_type>
<rdf:value>
<rdf:Bag>
<rdf:li>electrophysiology</rdf:li>
<rdf:li>cardiac</rdf:li>
</rdf:Bag>
</rdf:value>
</dc:subject>
</bqs:reference>
</rdf:Description>
</rdf:RDF>
</model>
