Model Status

This model was developed in CellML and runs in COR.

Model Structure

This model integrates a sinoatrial node model based on the work of Courtemanche et al. (1998), Chandler et al. (2009), and Verkerk et al. (2007). This is connected to a ventricular model, very similar to the approach of Shim et al. (2006). This, in turn, is connected to a lumped parameter, compartment model of the circulatory model. The cardiovascular model(s) are linked to a simple lung model from Athanasiades et al. (2000) via the gas exchange model of Liu et al. (1998).