<?xml version='1.0' encoding='UTF-8'?>
<model name="voigt_heijman_2013"
xmlns="http://www.cellml.org/cellml/1.0#"
xmlns:cellml="http://www.cellml.org/cellml/1.0#"
xmlns:cmeta="http://www.cellml.org/metadata/1.0#"
xmlns:bqbiol="http://biomodels.net/biology-qualifiers/"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:bqs="http://www.cellml.org/bqs/1.0#"
xmlns:dc="http://purl.org/dc/elements/1.1/"
cmeta:id="voigt_heijman_2013">
<units name="A_per_F">
<unit units="gram" multiplier="1000"/>
<unit units="metre" exponent="2.0"/>
<unit units="second" exponent="-4.0"/>
<unit units="ampere" exponent="-1.0"/>
</units>
<units name="C_per_mol">
<unit units="second"/>
<unit units="ampere"/>
<unit units="mole" exponent="-1.0"/>
</units>
<units name="cm2_per_uF">
<unit units="gram" multiplier="100000"/>
<unit units="metre" exponent="4.0"/>
<unit units="second" exponent="-4.0"/>
<unit units="ampere" exponent="-2.0"/>
</units>
<units name="cm_per_s">
<unit units="metre" multiplier="0.01"/>
<unit units="second" exponent="-1.0"/>
</units>
<units name="dimensionless_times_1e15">
<unit units="dimensionless" multiplier="1000000000000000"/>
</units>
<units name="m3_per_mol">
<unit units="metre" exponent="3.0"/>
<unit units="mole" exponent="-1.0"/>
</units>
<units name="m3_per_s">
<unit units="metre" exponent="3.0"/>
<unit units="second" exponent="-1.0"/>
</units>
<units name="mJ_per_mol_per_K">
<unit units="gram"/>
<unit units="metre" exponent="2.0"/>
<unit units="second" exponent="-2.0"/>
<unit units="kelvin" exponent="-1.0"/>
<unit units="mole" exponent="-1.0"/>
</units>
<units name="mM">
<unit units="metre" exponent="-3.0"/>
<unit units="mole"/>
</units>
<units name="mM_per_ms">
<unit units="metre" exponent="-3.0" multiplier="1000"/>
<unit units="second" exponent="-1.0"/>
<unit units="mole"/>
</units>
<units name="mS_per_uF">
<unit units="second" exponent="-1.0" multiplier="1000"/>
</units>
<units name="mV">
<unit units="gram"/>
<unit units="metre" exponent="2.0"/>
<unit units="second" exponent="-3.0"/>
<unit units="ampere" exponent="-1.0"/>
</units>
<units name="mol4_per_m12">
<unit units="metre" exponent="-12.0"/>
<unit units="mole" exponent="4.0"/>
</units>
<units name="ms">
<unit units="second" multiplier="0.001"/>
</units>
<units name="per_mM2_per_ms">
<unit units="metre" exponent="6.0" multiplier="1000"/>
<unit units="second" exponent="-1.0"/>
<unit units="mole" exponent="-2.0"/>
</units>
<units name="per_mM_per_ms">
<unit units="metre" exponent="3.0" multiplier="1000"/>
<unit units="second" exponent="-1.0"/>
<unit units="mole" exponent="-1.0"/>
</units>
<units name="per_mV">
<unit units="gram" exponent="-1.0"/>
<unit units="metre" exponent="-2.0"/>
<unit units="second" exponent="3.0"/>
<unit units="ampere"/>
</units>
<units name="per_mV_per_ms">
<unit units="gram" exponent="-1.0" multiplier="1000"/>
<unit units="metre" exponent="-2.0"/>
<unit units="second" exponent="2.0"/>
<unit units="ampere"/>
</units>
<units name="uA_per_cm2">
<unit units="metre" exponent="-2.0" multiplier="0.01"/>
<unit units="ampere"/>
</units>
<units name="um">
<unit units="metre" multiplier="1e-06"/>
</units>
<component name="buffca">
<variable name="Bmax_CaM" units="mM" initial_value="0.024"/>
<variable name="Bmax_SLhighjn" units="mM"/>
<variable name="Bmax_SLhighsl" units="mM"/>
<variable name="Bmax_SLlowjn" units="mM"/>
<variable name="Bmax_SLlowsl" units="mM"/>
<variable name="Bmax_SR" units="mM"/>
<variable name="Bmax_TnChigh" units="mM" initial_value="0.14"/>
<variable name="Bmax_TnClow" units="mM" initial_value="0.07"/>
<variable name="Bmax_myosin" units="mM" initial_value="0.14"/>
<variable name="CaM" units="mM" public_interface="out" initial_value="6.73710089221736985e-04"/>
<variable name="Ca_i" units="mM" public_interface="in"/>
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_sl" units="mM" public_interface="in"/>
<variable name="J_CaB_cytosol" units="mM_per_ms" public_interface="out"/>
<variable name="J_CaB_jn" units="mM_per_ms" public_interface="out"/>
<variable name="J_CaB_sl" units="mM_per_ms" public_interface="out"/>
<variable name="Mg_i" units="mM" public_interface="in"/>
<variable name="Myoc" units="mM" public_interface="out" initial_value="3.79608844523014136e-03"/>
<variable name="Myom" units="mM" public_interface="out" initial_value="1.35691489581683838e-01"/>
<variable name="SLH_jn" units="mM" public_interface="out" initial_value="1.00754933940878755e-01"/>
<variable name="SLH_sl" units="mM" public_interface="out" initial_value="1.86055242143676608e-01"/>
<variable name="SLL_jn" units="mM" public_interface="out" initial_value="1.28122161143722785e-02"/>
<variable name="SLL_sl" units="mM" public_interface="out" initial_value="2.05131045874987414e-02"/>
<variable name="SRB" units="mM" public_interface="out" initial_value="4.31383413366585346e-03"/>
<variable name="TnCHc" units="mM" public_interface="out" initial_value="1.27405935029765827e-01"/>
<variable name="TnCHm" units="mM" public_interface="out" initial_value="5.91106798633337510e-03"/>
<variable name="TnCL" units="mM" public_interface="out" initial_value="1.77305527980331397e-02"/>
<variable name="Vjn" units="litre" public_interface="in"/>
<variable name="Vmyo" units="litre" public_interface="in"/>
<variable name="Vsl" units="litre" public_interface="in"/>
<variable name="koff_cam" units="mS_per_uF" initial_value="0.238"/>
<variable name="koff_myoca" units="mS_per_uF" initial_value="0.00046"/>
<variable name="koff_myomg" units="mS_per_uF" initial_value="5.7e-05"/>
<variable name="koff_slh" units="mS_per_uF" initial_value="0.03"/>
<variable name="koff_sll" units="mS_per_uF" initial_value="1.3"/>
<variable name="koff_sr" units="mS_per_uF" initial_value="0.06"/>
<variable name="koff_tnchca" units="mS_per_uF" initial_value="3.2e-05"/>
<variable name="koff_tnchmg" units="mS_per_uF" initial_value="0.00333"/>
<variable name="koff_tncl" units="mS_per_uF" initial_value="0.0196"/>
<variable name="kon_cam" units="per_mM_per_ms" initial_value="34.0"/>
<variable name="kon_myoca" units="per_mM_per_ms" initial_value="13.8"/>
<variable name="kon_myomg" units="per_mM_per_ms" initial_value="0.0157"/>
<variable name="kon_slh" units="per_mM_per_ms" initial_value="100.0"/>
<variable name="kon_sll" units="per_mM_per_ms" initial_value="100.0"/>
<variable name="kon_sr" units="per_mM_per_ms" initial_value="100.0"/>
<variable name="kon_tnchca" units="per_mM_per_ms" initial_value="2.37"/>
<variable name="kon_tnchmg" units="per_mM_per_ms" initial_value="0.003"/>
<variable name="kon_tncl" units="per_mM_per_ms" initial_value="32.7"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Bmax_SLhighjn</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="mM">0.00165</cn>
<ci>Vmyo</ci>
</apply>
<ci>Vjn</ci>
</apply>
<cn cellml:units="dimensionless">0.1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Bmax_SLhighsl</ci>
<apply>
<times/>
<apply>
<divide/>
<ci>Vmyo</ci>
<ci>Vsl</ci>
</apply>
<cn cellml:units="mM">0.0134</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Bmax_SLlowjn</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="mM">0.0046</cn>
<ci>Vmyo</ci>
</apply>
<ci>Vjn</ci>
</apply>
<cn cellml:units="dimensionless">0.1</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Bmax_SLlowsl</ci>
<apply>
<times/>
<apply>
<divide/>
<ci>Vmyo</ci>
<ci>Vsl</ci>
</apply>
<cn cellml:units="mM">0.0374</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Bmax_SR</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">19.0</cn>
<cn cellml:units="mM">0.0009</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>CaM</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_cam</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<minus/>
<ci>Bmax_CaM</ci>
<ci>CaM</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_cam</ci>
<ci>CaM</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>J_CaB_cytosol</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<ci>TnCL</ci>
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<apply>
<diff/>
<bvar>
<ci>time</ci>
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<ci>TnCHc</ci>
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<apply>
<diff/>
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<ci>TnCHm</ci>
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</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>CaM</ci>
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</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Myoc</ci>
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</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Myom</ci>
</apply>
</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>SRB</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>J_CaB_jn</ci>
<apply>
<plus/>
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<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>SLL_jn</ci>
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<bvar>
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<apply>
<eq/>
<ci>J_CaB_sl</ci>
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<plus/>
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<diff/>
<bvar>
<ci>time</ci>
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<apply>
<eq/>
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<diff/>
<bvar>
<ci>time</ci>
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<apply>
<minus/>
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<times/>
<apply>
<times/>
<ci>kon_myoca</ci>
<ci>Ca_i</ci>
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<apply>
<minus/>
<apply>
<minus/>
<ci>Bmax_myosin</ci>
<ci>Myoc</ci>
</apply>
<ci>Myom</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_myoca</ci>
<ci>Myoc</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Myom</ci>
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<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_myomg</ci>
<ci>Mg_i</ci>
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<apply>
<minus/>
<apply>
<minus/>
<ci>Bmax_myosin</ci>
<ci>Myoc</ci>
</apply>
<ci>Myom</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_myomg</ci>
<ci>Myom</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<ci>SLH_jn</ci>
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<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_slh</ci>
<ci>Ca_jn</ci>
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<apply>
<minus/>
<ci>Bmax_SLhighjn</ci>
<ci>SLH_jn</ci>
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</apply>
<apply>
<times/>
<ci>koff_slh</ci>
<ci>SLH_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>SLH_sl</ci>
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<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_slh</ci>
<ci>Ca_sl</ci>
</apply>
<apply>
<minus/>
<ci>Bmax_SLhighsl</ci>
<ci>SLH_sl</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_slh</ci>
<ci>SLH_sl</ci>
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</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>SLL_jn</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_sll</ci>
<ci>Ca_jn</ci>
</apply>
<apply>
<minus/>
<ci>Bmax_SLlowjn</ci>
<ci>SLL_jn</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_sll</ci>
<ci>SLL_jn</ci>
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</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>SLL_sl</ci>
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<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_sll</ci>
<ci>Ca_sl</ci>
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<apply>
<minus/>
<ci>Bmax_SLlowsl</ci>
<ci>SLL_sl</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_sll</ci>
<ci>SLL_sl</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>SRB</ci>
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<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_sr</ci>
<ci>Ca_i</ci>
</apply>
<apply>
<minus/>
<ci>Bmax_SR</ci>
<ci>SRB</ci>
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</apply>
<apply>
<times/>
<ci>koff_sr</ci>
<ci>SRB</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<ci>TnCHc</ci>
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<apply>
<minus/>
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<times/>
<apply>
<times/>
<ci>kon_tnchca</ci>
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<apply>
<minus/>
<apply>
<minus/>
<ci>Bmax_TnChigh</ci>
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<ci>TnCHm</ci>
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<apply>
<times/>
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<ci>TnCHc</ci>
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<apply>
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<diff/>
<bvar>
<ci>time</ci>
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<minus/>
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<times/>
<apply>
<times/>
<ci>kon_tnchmg</ci>
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<apply>
<minus/>
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<minus/>
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<ci>TnCHc</ci>
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<apply>
<times/>
<ci>koff_tnchmg</ci>
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<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
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<minus/>
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<times/>
<apply>
<times/>
<ci>kon_tncl</ci>
<ci>Ca_i</ci>
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<minus/>
<ci>Bmax_TnClow</ci>
<ci>TnCL</ci>
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</apply>
<apply>
<times/>
<ci>koff_tncl</ci>
<ci>TnCL</ci>
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</apply>
</apply>
</math>
</component>
<component name="buffna">
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<variable name="Bmax_Na_sl" units="mM" initial_value="1.65"/>
<variable name="NaB_jn" units="mM" public_interface="out" initial_value="3.62527560419928152e+00"/>
<variable name="NaB_sl" units="mM" public_interface="out" initial_value="7.91087217252140484e-01"/>
<variable name="Na_jn" units="mM" public_interface="in"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<variable name="koff_na" units="mS_per_uF" initial_value="0.001"/>
<variable name="kon_na" units="per_mM_per_ms" initial_value="0.0001"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
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<diff/>
<bvar>
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<minus/>
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<times/>
<apply>
<times/>
<ci>kon_na</ci>
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<apply>
<minus/>
<ci>Bmax_Na_jn</ci>
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<times/>
<ci>koff_na</ci>
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<apply>
<eq/>
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<diff/>
<bvar>
<ci>time</ci>
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<minus/>
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<times/>
<apply>
<times/>
<ci>kon_na</ci>
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<apply>
<minus/>
<ci>Bmax_Na_sl</ci>
<ci>NaB_sl</ci>
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</apply>
<apply>
<times/>
<ci>koff_na</ci>
<ci>NaB_sl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="calcium">
<variable name="Bmax_Csqn" units="mM"/>
<variable name="C" units="farad" public_interface="in"/>
<variable name="Ca_i" units="mM" public_interface="out" initial_value="2.02054825252250719e-04"/>
<variable name="Ca_jn" units="mM" public_interface="out" initial_value="3.07333085373605341e-04"/>
<variable name="Ca_sl" units="mM" public_interface="out" initial_value="2.23134214147860355e-04"/>
<variable name="Ca_sr" units="mM" public_interface="out" initial_value="4.85784491491899340e-01"/>
<variable name="Csqn" units="mM" public_interface="out" initial_value="1.11204132576763315e+00"/>
<variable name="F" units="C_per_mol" public_interface="in"/>
<variable name="ICaB_jn" units="A_per_F" public_interface="in"/>
<variable name="ICaB_sl" units="A_per_F" public_interface="in"/>
<variable name="ICaL_Ca_jn" units="A_per_F" public_interface="in"/>
<variable name="ICaL_Ca_sl" units="A_per_F" public_interface="in"/>
<variable name="ICa_tot_jn" units="A_per_F" public_interface="out"/>
<variable name="ICa_tot_sl" units="A_per_F" public_interface="out"/>
<variable name="INaCa_jn" units="A_per_F" public_interface="in"/>
<variable name="INaCa_sl" units="A_per_F" public_interface="in"/>
<variable name="IpCa_jn" units="A_per_F" public_interface="in"/>
<variable name="IpCa_sl" units="A_per_F" public_interface="in"/>
<variable name="JCa_jnsl" units="m3_per_s"/>
<variable name="JCa_slmyo" units="m3_per_s"/>
<variable name="J_CaB_cytosol" units="mM_per_ms" public_interface="in"/>
<variable name="J_CaB_jn" units="mM_per_ms" public_interface="in"/>
<variable name="J_CaB_sl" units="mM_per_ms" public_interface="in"/>
<variable name="J_SRCarel" units="mM_per_ms" public_interface="in"/>
<variable name="J_SRleak" units="mM_per_ms" public_interface="in"/>
<variable name="J_serca" units="mM_per_ms" public_interface="in"/>
<variable name="Vjn" units="litre" public_interface="in"/>
<variable name="Vmyo" units="litre" public_interface="in"/>
<variable name="Vsl" units="litre" public_interface="in"/>
<variable name="Vsr" units="litre" public_interface="in"/>
<variable name="koff_csqn" units="mS_per_uF" initial_value="65.0"/>
<variable name="kon_csqn" units="per_mM_per_ms" initial_value="100.0"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
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<eq/>
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<times/>
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<divide/>
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<cn cellml:units="mM">0.14</cn>
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<minus/>
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<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>J_serca</ci>
</apply>
<ci>Vsr</ci>
</apply>
<ci>Vmyo</ci>
</apply>
<ci>J_CaB_cytosol</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JCa_slmyo</ci>
<ci>Vmyo</ci>
</apply>
<apply>
<minus/>
<ci>Ca_sl</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_jn</ci>
</apply>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>ICa_tot_jn</ci>
</apply>
<ci>C</ci>
</apply>
<apply>
<times/>
<apply>
<times/>
<ci>Vjn</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
<ci>F</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JCa_jnsl</ci>
<ci>Vjn</ci>
</apply>
<apply>
<minus/>
<ci>Ca_sl</ci>
<ci>Ca_jn</ci>
</apply>
</apply>
</apply>
<ci>J_CaB_jn</ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>J_SRCarel</ci>
<ci>Vsr</ci>
</apply>
<ci>Vjn</ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci>J_SRleak</ci>
<ci>Vmyo</ci>
</apply>
<ci>Vjn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_sl</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>ICa_tot_sl</ci>
</apply>
<ci>C</ci>
</apply>
<apply>
<times/>
<apply>
<times/>
<ci>Vsl</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
<ci>F</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JCa_jnsl</ci>
<ci>Vsl</ci>
</apply>
<apply>
<minus/>
<ci>Ca_jn</ci>
<ci>Ca_sl</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JCa_slmyo</ci>
<ci>Vsl</ci>
</apply>
<apply>
<minus/>
<ci>Ca_i</ci>
<ci>Ca_sl</ci>
</apply>
</apply>
</apply>
<ci>J_CaB_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Ca_sr</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<ci>J_serca</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<ci>J_SRleak</ci>
<ci>Vmyo</ci>
</apply>
<ci>Vsr</ci>
</apply>
<ci>J_SRCarel</ci>
</apply>
</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Csqn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Csqn</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kon_csqn</ci>
<ci>Ca_sr</ci>
</apply>
<apply>
<minus/>
<ci>Bmax_Csqn</ci>
<ci>Csqn</ci>
</apply>
</apply>
<apply>
<times/>
<ci>koff_csqn</ci>
<ci>Csqn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICa_tot_jn</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<plus/>
<ci>ICaL_Ca_jn</ci>
<ci>ICaB_jn</ci>
</apply>
<ci>IpCa_jn</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>INaCa_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICa_tot_sl</ci>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<plus/>
<ci>ICaL_Ca_sl</ci>
<ci>ICaB_sl</ci>
</apply>
<ci>IpCa_sl</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>INaCa_sl</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JCa_jnsl</ci>
<apply>
<divide/>
<cn cellml:units="m3_per_s">1.0</cn>
<cn cellml:units="dimensionless"> 1.21340000000000000e+12</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>JCa_slmyo</ci>
<apply>
<divide/>
<cn cellml:units="m3_per_s">1.0</cn>
<cn cellml:units="dimensionless"> 2.68510000000000000e+11</cn>
</apply>
</apply>
</math>
</component>
<component name="cell">
<variable name="AF" units="dimensionless" public_interface="out" initial_value="0.0"/>
<variable name="C" units="farad" public_interface="out" initial_value="1.381e-10"/>
</component>
<component name="engine">
<variable name="CaM" units="mM" public_interface="in"/>
<variable name="Csqn" units="mM" public_interface="in"/>
<variable name="Myoc" units="mM" public_interface="in"/>
<variable name="Myom" units="mM" public_interface="in"/>
<variable name="NaB_jn" units="mM" public_interface="in"/>
<variable name="NaB_sl" units="mM" public_interface="in"/>
<variable name="SLH_jn" units="mM" public_interface="in"/>
<variable name="SLH_sl" units="mM" public_interface="in"/>
<variable name="SLL_jn" units="mM" public_interface="in"/>
<variable name="SLL_sl" units="mM" public_interface="in"/>
<variable name="SRB" units="mM" public_interface="in"/>
<variable name="TnCHc" units="mM" public_interface="in"/>
<variable name="TnCHm" units="mM" public_interface="in"/>
<variable name="TnCL" units="mM" public_interface="in"/>
<variable name="time" units="ms" public_interface="out"/>
</component>
<component name="geom">
<variable name="Vcell" units="litre"/>
<variable name="Vjn" units="litre" public_interface="out"/>
<variable name="Vmyo" units="litre" public_interface="out"/>
<variable name="Vsl" units="litre" public_interface="out"/>
<variable name="Vsr" units="litre" public_interface="out"/>
<variable name="cell_length" units="um" initial_value="100.0"/>
<variable name="cell_radius" units="um" initial_value="10.25"/>
<variable name="pi" units="dimensionless" initial_value="3.14159265358979312e+00"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Vcell</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>pi</ci>
<apply>
<power/>
<ci>cell_radius</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
<ci>cell_length</ci>
</apply>
<cn cellml:units="dimensionless_times_1e15">1e-15</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Vjn</ci>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0539</cn>
<cn cellml:units="dimensionless">0.01</cn>
</apply>
<ci>Vcell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Vmyo</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.65</cn>
<ci>Vcell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Vsl</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.02</cn>
<ci>Vcell</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Vsr</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.035</cn>
<ci>Vcell</ci>
</apply>
</apply>
</math>
</component>
<component name="icab">
<variable name="ECa_jn" units="mV" public_interface="in"/>
<variable name="ECa_sl" units="mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="ICaB" units="A_per_F"/>
<variable name="ICaB_jn" units="A_per_F" public_interface="out"/>
<variable name="ICaB_sl" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gCaB" units="mS_per_uF" initial_value="6.06430000000000033e-04"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICaB</ci>
<apply>
<plus/>
<ci>ICaB_jn</ci>
<ci>ICaB_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaB_jn</ci>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>gCaB</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ECa_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaB_sl</ci>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gCaB</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ECa_sl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ical">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_o" units="mM" public_interface="in"/>
<variable name="Ca_sl" units="mM" public_interface="in"/>
<variable name="F" units="C_per_mol" public_interface="in"/>
<variable name="FRT" units="per_mV" public_interface="in"/>
<variable name="Fjn_CaL" units="dimensionless" public_interface="in"/>
<variable name="Fsl_CaL" units="dimensionless" public_interface="in"/>
<variable name="ICaL" units="A_per_F"/>
<variable name="ICaL_Ca" units="A_per_F"/>
<variable name="ICaL_Ca_jn" units="A_per_F" public_interface="out"/>
<variable name="ICaL_Ca_sl" units="A_per_F" public_interface="out"/>
<variable name="ICaL_K" units="A_per_F" public_interface="out"/>
<variable name="ICaL_Na" units="A_per_F"/>
<variable name="ICaL_Na_jn" units="A_per_F" public_interface="out"/>
<variable name="ICaL_Na_sl" units="A_per_F" public_interface="out"/>
<variable name="K_i" units="mM" public_interface="in"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="Na_jn" units="mM" public_interface="in"/>
<variable name="Na_o" units="mM" public_interface="in"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<variable name="Q" units="dimensionless" public_interface="in"/>
<variable name="Q10CaL" units="dimensionless" initial_value="1.8"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="d" units="mS_per_uF" initial_value="1.67750282273476489e-05"/>
<variable name="f" units="mS_per_uF" initial_value="9.98760022198537767e-01"/>
<variable name="fCaB_jn" units="mS_per_uF" initial_value="4.24066845471226944e-02"/>
<variable name="fCaB_sl" units="mS_per_uF" initial_value="3.13717989771996886e-02"/>
<variable name="fcaCaMSL" units="dimensionless" initial_value="0.0"/>
<variable name="fcaCaj" units="dimensionless" initial_value="0.0"/>
<variable name="ibarca_jn" units="uA_per_cm2"/>
<variable name="ibarca_sl" units="uA_per_cm2"/>
<variable name="ibark" units="uA_per_cm2"/>
<variable name="ibarna_jn" units="uA_per_cm2"/>
<variable name="ibarna_sl" units="uA_per_cm2"/>
<variable name="ical_d_inf" units="dimensionless"/>
<variable name="ical_d_tau" units="ms"/>
<variable name="ical_f_inf" units="dimensionless"/>
<variable name="ical_f_tau" units="ms"/>
<variable name="pCa" units="cm_per_s"/>
<variable name="pK" units="cm_per_s"/>
<variable name="pNa" units="cm_per_s"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICaL</ci>
<apply>
<plus/>
<apply>
<plus/>
<ci>ICaL_Ca</ci>
<ci>ICaL_Na</ci>
</apply>
<ci>ICaL_K</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_Ca</ci>
<apply>
<plus/>
<ci>ICaL_Ca_jn</ci>
<ci>ICaL_Ca_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_Ca_jn</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn_CaL</ci>
<ci>ibarca_jn</ci>
</apply>
<ci>d</ci>
</apply>
<ci>f</ci>
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<apply>
<plus/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_jn</ci>
</apply>
<ci>fcaCaj</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Q10CaL</ci>
<ci>Q</ci>
</apply>
</apply>
<cn cellml:units="cm2_per_uF">0.45</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_Ca_sl</ci>
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<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl_CaL</ci>
<ci>ibarca_sl</ci>
</apply>
<ci>d</ci>
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<ci>f</ci>
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<apply>
<plus/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_sl</ci>
</apply>
<ci>fcaCaMSL</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Q10CaL</ci>
<ci>Q</ci>
</apply>
</apply>
<cn cellml:units="cm2_per_uF">0.45</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_K</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>ibark</ci>
<ci>d</ci>
</apply>
<ci>f</ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>Fjn_CaL</ci>
<apply>
<plus/>
<ci>fcaCaj</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_jn</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>Fsl_CaL</ci>
<apply>
<plus/>
<ci>fcaCaMSL</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_sl</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<power/>
<ci>Q10CaL</ci>
<ci>Q</ci>
</apply>
</apply>
<cn cellml:units="cm2_per_uF">0.45</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_Na</ci>
<apply>
<plus/>
<ci>ICaL_Na_jn</ci>
<ci>ICaL_Na_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_Na_jn</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn_CaL</ci>
<ci>ibarna_jn</ci>
</apply>
<ci>d</ci>
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<ci>f</ci>
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<apply>
<plus/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_jn</ci>
</apply>
<ci>fcaCaj</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Q10CaL</ci>
<ci>Q</ci>
</apply>
</apply>
<cn cellml:units="cm2_per_uF">0.45</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ICaL_Na_sl</ci>
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<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl_CaL</ci>
<ci>ibarna_sl</ci>
</apply>
<ci>d</ci>
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<ci>f</ci>
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<apply>
<plus/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_sl</ci>
</apply>
<ci>fcaCaMSL</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Q10CaL</ci>
<ci>Q</ci>
</apply>
</apply>
<cn cellml:units="cm2_per_uF">0.45</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d</ci>
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<apply>
<divide/>
<apply>
<minus/>
<ci>ical_d_inf</ci>
<ci>d</ci>
</apply>
<ci>ical_d_tau</ci>
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</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f</ci>
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<apply>
<divide/>
<apply>
<minus/>
<ci>ical_f_inf</ci>
<ci>f</ci>
</apply>
<ci>ical_f_tau</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fCaB_jn</ci>
</apply>
<apply>
<times/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="m3_per_mol">1.7</cn>
<ci>Ca_jn</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_jn</ci>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0119</cn>
<ci>fCaB_jn</ci>
</apply>
</apply>
<cn cellml:units="mS_per_uF">1.0</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>fCaB_sl</ci>
</apply>
<apply>
<times/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="m3_per_mol">1.7</cn>
<ci>Ca_sl</ci>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>fCaB_sl</ci>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0119</cn>
<ci>fCaB_sl</ci>
</apply>
</apply>
<cn cellml:units="mS_per_uF">1.0</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ibarca_jn</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>pCa</ci>
<cn cellml:units="dimensionless">4.0</cn>
</apply>
<ci>V</ci>
</apply>
<ci>F</ci>
</apply>
<ci>FRT</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>Ca_jn</ci>
</apply>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>Ca_o</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ibarca_sl</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>pCa</ci>
<cn cellml:units="dimensionless">4.0</cn>
</apply>
<ci>V</ci>
</apply>
<ci>F</ci>
</apply>
<ci>FRT</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>Ca_sl</ci>
</apply>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.341</cn>
<ci>Ca_o</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ibark</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>pK</ci>
<ci>V</ci>
</apply>
<ci>F</ci>
</apply>
<ci>FRT</ci>
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<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>K_i</ci>
</apply>
<apply>
<exp/>
<apply>
<times/>
<ci>V</ci>
<ci>FRT</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>K_o</ci>
</apply>
</apply>
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<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<ci>V</ci>
<ci>FRT</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ibarna_jn</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>pNa</ci>
<ci>V</ci>
</apply>
<ci>F</ci>
</apply>
<ci>FRT</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>Na_jn</ci>
</apply>
<apply>
<exp/>
<apply>
<times/>
<ci>V</ci>
<ci>FRT</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>Na_o</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<ci>V</ci>
<ci>FRT</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ibarna_sl</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>pNa</ci>
<ci>V</ci>
</apply>
<ci>F</ci>
</apply>
<ci>FRT</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>Na_sl</ci>
</apply>
<apply>
<exp/>
<apply>
<times/>
<ci>V</ci>
<ci>FRT</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">0.75</cn>
<ci>Na_o</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<times/>
<ci>V</ci>
<ci>FRT</ci>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ical_d_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">9.0</cn>
</apply>
</apply>
<cn cellml:units="mV">6.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ical_d_tau</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>ical_d_inf</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">9.0</cn>
</apply>
</apply>
<cn cellml:units="mV">6.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="per_mV_per_ms">0.035</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">9.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ical_f_inf</ci>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">30.0</cn>
</apply>
<cn cellml:units="mV">7.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.2</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<cn cellml:units="mV">50.0</cn>
<ci>V</ci>
</apply>
<cn cellml:units="mV">20.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ical_f_tau</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.0197</cn>
<apply>
<exp/>
<apply>
<minus/>
<apply>
<power/>
<apply>
<times/>
<cn cellml:units="per_mV">0.0337</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">25.0</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="mS_per_uF">0.02</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>pCa</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="cm_per_s">0.00027</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>pK</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="cm_per_s">1.35e-07</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>pNa</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="cm_per_s">7.5e-09</cn>
</apply>
</apply>
</math>
</component>
<component name="iclb">
<variable name="ECl" units="mV" public_interface="in"/>
<variable name="IClB" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gClB" units="mS_per_uF" initial_value="0.009"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IClB</ci>
<apply>
<times/>
<ci>gClB</ci>
<apply>
<minus/>
<ci>V</ci>
<ci>ECl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="iclca">
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_sl" units="mM" public_interface="in"/>
<variable name="ECl" units="mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="IClCa" units="A_per_F" public_interface="out"/>
<variable name="IClCa_jn" units="A_per_F"/>
<variable name="IClCa_sl" units="A_per_F"/>
<variable name="KdClCa" units="mM" initial_value="0.1"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gClCa" units="mS_per_uF" initial_value="0.0548"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IClCa</ci>
<apply>
<plus/>
<ci>IClCa_jn</ci>
<ci>IClCa_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>IClCa_jn</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>gClCa</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<divide/>
<ci>KdClCa</ci>
<ci>Ca_jn</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ECl</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>IClCa_sl</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gClCa</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<divide/>
<ci>KdClCa</ci>
<ci>Ca_sl</ci>
</apply>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ECl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ik1">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="EK" units="mV" public_interface="in"/>
<variable name="IK1" units="A_per_F" public_interface="out"/>
<variable name="IK1_Fact" units="dimensionless" initial_value="2.1"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="Na_observed" units="mM"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="a_fact" units="dimensionless"/>
<variable name="gK1" units="mS_per_uF"/>
<variable name="ik1_inf_a" units="mS_per_uF"/>
<variable name="ik1_inf_b" units="mS_per_uF"/>
<variable name="inf" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IK1</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>IK1_Fact</ci>
<ci>gK1</ci>
</apply>
<ci>inf</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Na_observed</ci>
<ci>Na_sl</ci>
</apply>
<apply>
<eq/>
<ci>a_fact</ci>
<apply>
<plus/>
<cn cellml:units="dimensionless">0.1</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.9</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Na_observed</ci>
<cn cellml:units="mM">7.0</cn>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gK1</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>AF</ci>
</apply>
<apply>
<root/>
<apply>
<divide/>
<ci>K_o</ci>
<cn cellml:units="mM">5.4</cn>
</apply>
</apply>
</apply>
<cn cellml:units="mS_per_uF">0.0525</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ik1_inf_a</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>a_fact</ci>
<cn cellml:units="mS_per_uF">1.0</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.2385</cn>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
<cn cellml:units="mV">59.215</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ik1_inf_b</ci>
<apply>
<times/>
<cn cellml:units="mS_per_uF">1.0</cn>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.49124</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.08032</cn>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
<cn cellml:units="mV">5.476</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.06175</cn>
<apply>
<minus/>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
<cn cellml:units="mV">594.31</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.5143</cn>
</apply>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
<cn cellml:units="mV">4.753</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>inf</ci>
<apply>
<divide/>
<ci>ik1_inf_a</ci>
<apply>
<plus/>
<ci>ik1_inf_a</ci>
<ci>ik1_inf_b</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ikach">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="Act" units="dimensionless"/>
<variable name="CCh" units="dimensionless" initial_value="0.0"/>
<variable name="Constitutive_Frac" units="dimensionless" initial_value="0.0"/>
<variable name="EK" units="mV" public_interface="in"/>
<variable name="IKACh" units="A_per_F" public_interface="out"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="Na_dep" units="dimensionless"/>
<variable name="Na_observed" units="mM"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gKACh" units="mS_per_uF"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Act</ci>
<apply>
<plus/>
<ci>Constitutive_Frac</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Constitutive_Frac</ci>
</apply>
<ci>CCh</ci>
</apply>
<apply>
<plus/>
<ci>CCh</ci>
<cn cellml:units="dimensionless">0.125</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>IKACh</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>gKACh</ci>
<ci>Na_dep</ci>
</apply>
<ci>Act</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">0.055</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">0.4</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
<cn cellml:units="mV">9.53</cn>
</apply>
<cn cellml:units="mV">17.18</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
</apply>
<apply>
<root/>
<apply>
<divide/>
<ci>K_o</ci>
<cn cellml:units="mM">5.4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Na_dep</ci>
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<piece>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.5</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<cn cellml:units="mM">9.0</cn>
<ci>Na_observed</ci>
</apply>
<cn cellml:units="dimensionless">4.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>AF</ci>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
</piece>
<otherwise>
<cn cellml:units="dimensionless">1.0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>Na_observed</ci>
<ci>Na_sl</ci>
</apply>
<apply>
<eq/>
<ci>gKACh</ci>
<apply>
<minus/>
<cn cellml:units="mS_per_uF">0.1</cn>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.05</cn>
<ci>AF</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ikp">
<variable name="EK" units="mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="IKp" units="A_per_F" public_interface="out"/>
<variable name="IKp_jn" units="A_per_F"/>
<variable name="IKp_sl" units="A_per_F"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gKp" units="mS_per_uF" initial_value="0.002"/>
<variable name="kp" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IKp</ci>
<apply>
<plus/>
<ci>IKp_jn</ci>
<ci>IKp_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>IKp_jn</ci>
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<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
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<ci>kp</ci>
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<apply>
<minus/>
<ci>V</ci>
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</apply>
</apply>
<apply>
<eq/>
<ci>IKp_sl</ci>
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<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gKp</ci>
</apply>
<ci>kp</ci>
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<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
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</apply>
</apply>
<apply>
<eq/>
<ci>kp</ci>
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<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<minus/>
<cn cellml:units="dimensionless">7.488</cn>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">5.98</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ikr">
<variable name="EK" units="mV" public_interface="in"/>
<variable name="IKr" units="A_per_F" public_interface="out"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gKr" units="mS_per_uF"/>
<variable name="ikr_x_inf" units="dimensionless"/>
<variable name="ikr_x_tau" units="ms"/>
<variable name="r" units="dimensionless"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="x" units="mS_per_uF" initial_value="4.42405976310802831e-03"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IKr</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>gKr</ci>
<ci>x</ci>
</apply>
<ci>r</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gKr</ci>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.035</cn>
<apply>
<root/>
<apply>
<divide/>
<ci>K_o</ci>
<cn cellml:units="mM">5.4</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ikr_x_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
<cn cellml:units="mV">5.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ikr_x_tau</ci>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<divide/>
<apply>
<plus/>
<cn cellml:units="ms">550.0</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="mV">22.0</cn>
</apply>
<ci>V</ci>
</apply>
<cn cellml:units="mV">9.0</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="dimensionless">6.0</cn>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">11.0</cn>
</apply>
<cn cellml:units="mV">9.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn cellml:units="ms">230.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">40.0</cn>
</apply>
<cn cellml:units="mV">20.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>r</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">74.0</cn>
</apply>
<cn cellml:units="mV">24.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>x</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ikr_x_inf</ci>
<ci>x</ci>
</apply>
<ci>ikr_x_tau</ci>
</apply>
</apply>
</math>
</component>
<component name="iks">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="EKs" units="mV"/>
<variable name="FRT" units="per_mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="IKs" units="A_per_F" public_interface="out"/>
<variable name="IKs_jn" units="A_per_F"/>
<variable name="IKs_sl" units="A_per_F"/>
<variable name="K_i" units="mM" public_interface="in"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="Na_i" units="mM" public_interface="in"/>
<variable name="Na_o" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gKs_jn" units="mS_per_uF"/>
<variable name="gKs_sl" units="mS_per_uF"/>
<variable name="iks_x_inf" units="dimensionless"/>
<variable name="iks_x_tau" units="ms"/>
<variable name="pNaK" units="dimensionless" initial_value="0.01833"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="x" units="mS_per_uF" initial_value="6.73017121702351208e-03"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>EKs</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<apply>
<plus/>
<ci>K_o</ci>
<apply>
<times/>
<ci>pNaK</ci>
<ci>Na_o</ci>
</apply>
</apply>
<apply>
<plus/>
<ci>K_i</ci>
<apply>
<times/>
<ci>pNaK</ci>
<ci>Na_i</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>IKs</ci>
<apply>
<plus/>
<ci>IKs_jn</ci>
<ci>IKs_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>IKs_jn</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>gKs_jn</ci>
</apply>
<apply>
<power/>
<ci>x</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EKs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>IKs_sl</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gKs_sl</ci>
</apply>
<apply>
<power/>
<ci>x</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EKs</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gKs_jn</ci>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>AF</ci>
</apply>
<cn cellml:units="mS_per_uF">0.0035</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>gKs_sl</ci>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>AF</ci>
</apply>
<cn cellml:units="mS_per_uF">0.0035</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>iks_x_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">3.8</cn>
</apply>
</apply>
<cn cellml:units="mV">14.25</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>iks_x_tau</ci>
<apply>
<divide/>
<cn cellml:units="ms">990.1</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">2.436</cn>
</apply>
</apply>
<cn cellml:units="mV">14.12</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>x</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>iks_x_inf</ci>
<ci>x</ci>
</apply>
<ci>iks_x_tau</ci>
</apply>
</apply>
</math>
</component>
<component name="ikur">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="EK" units="mV" public_interface="in"/>
<variable name="IKur" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gKur" units="mS_per_uF"/>
<variable name="ikur_r_inf" units="dimensionless"/>
<variable name="ikur_r_tau" units="ms"/>
<variable name="ikur_s_inf" units="dimensionless"/>
<variable name="ikur_s_tau" units="ms"/>
<variable name="r" units="mS_per_uF" initial_value="3.28872423495696863e-04"/>
<variable name="s" units="mS_per_uF" initial_value="9.62950458643225149e-01"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IKur</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>gKur</ci>
<ci>r</ci>
</apply>
<ci>s</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gKur</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="mS_per_uF">0.045</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ikur_r_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">6.0</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="mV">8.6</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ikur_r_tau</ci>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="ms">9.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">5.0</cn>
</apply>
<cn cellml:units="mV">12.0</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="ms">0.5</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ikur_s_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">7.5</cn>
</apply>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ikur_s_tau</ci>
<apply>
<plus/>
<apply>
<divide/>
<cn cellml:units="ms">590.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">60.0</cn>
</apply>
<cn cellml:units="mV">10.0</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="ms">3050.0</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>r</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ikur_r_inf</ci>
<ci>r</ci>
</apply>
<ci>ikur_r_tau</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>s</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ikur_s_inf</ci>
<ci>s</ci>
</apply>
<ci>ikur_s_tau</ci>
</apply>
</apply>
</math>
</component>
<component name="ina">
<variable name="ENa_jn" units="mV" public_interface="in"/>
<variable name="ENa_sl" units="mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="INa" units="A_per_F"/>
<variable name="INa_jn" units="A_per_F" public_interface="out"/>
<variable name="INa_sl" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gNa" units="mS_per_uF" initial_value="23.0"/>
<variable name="h" units="mS_per_uF" initial_value="8.70955463748630310e-01"/>
<variable name="ina_h_alpha" units="mS_per_uF"/>
<variable name="ina_h_beta" units="mS_per_uF"/>
<variable name="ina_h_inf" units="dimensionless"/>
<variable name="ina_h_tau" units="ms"/>
<variable name="ina_j_alpha" units="mS_per_uF"/>
<variable name="ina_j_beta" units="mS_per_uF"/>
<variable name="ina_j_inf" units="dimensionless"/>
<variable name="ina_j_tau" units="ms"/>
<variable name="ina_m_alpha" units="mS_per_uF"/>
<variable name="ina_m_beta" units="mS_per_uF"/>
<variable name="ina_m_inf" units="dimensionless"/>
<variable name="ina_m_tau" units="ms"/>
<variable name="j" units="mS_per_uF" initial_value="8.92501441492474679e-01"/>
<variable name="m" units="mS_per_uF" initial_value="7.97426794491632243e-03"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INa</ci>
<apply>
<plus/>
<ci>INa_jn</ci>
<ci>INa_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INa_jn</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>gNa</ci>
</apply>
<apply>
<power/>
<ci>m</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>h</ci>
</apply>
<ci>j</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ENa_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INa_sl</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gNa</ci>
</apply>
<apply>
<power/>
<ci>m</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>h</ci>
</apply>
<ci>j</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ENa_sl</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>h</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ina_h_inf</ci>
<ci>h</ci>
</apply>
<ci>ina_h_tau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_h_alpha</ci>
<piecewise>
<piece>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.135</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">80.0</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="mV">6.8</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40.0</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="mS_per_uF">0.0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ina_h_beta</ci>
<piecewise>
<piece>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="mS_per_uF">3.56</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.079</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="mS_per_uF">310000.0</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.35</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40.0</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="ms">0.13</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">10.66</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="mV">11.1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ina_h_inf</ci>
<apply>
<divide/>
<ci>ina_h_alpha</ci>
<apply>
<plus/>
<ci>ina_h_alpha</ci>
<ci>ina_h_beta</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_h_tau</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<ci>ina_h_alpha</ci>
<ci>ina_h_beta</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_j_alpha</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV_per_ms">127140.0</cn>
</apply>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.2444</cn>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="per_mV_per_ms">3.474e-05</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.04391</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">37.78</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<cn cellml:units="per_mV">0.311</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">79.23</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40.0</cn>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="mS_per_uF">0.0</cn>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ina_j_beta</ci>
<piecewise>
<piece>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.1212</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.01052</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.1378</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">40.14</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<lt/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">40.0</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.3</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">2.535e-07</cn>
</apply>
<ci>V</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.1</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">32.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ina_j_inf</ci>
<apply>
<divide/>
<ci>ina_j_alpha</ci>
<apply>
<plus/>
<ci>ina_j_alpha</ci>
<ci>ina_j_beta</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_j_tau</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<ci>ina_j_alpha</ci>
<ci>ina_j_beta</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_m_alpha</ci>
<piecewise>
<piece>
<cn cellml:units="mS_per_uF">3.2</cn>
<apply>
<eq/>
<ci>V</ci>
<apply>
<minus/>
<cn cellml:units="mV">47.13</cn>
</apply>
</apply>
</piece>
<otherwise>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_mV_per_ms">0.32</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">47.13</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.1</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">47.13</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</otherwise>
</piecewise>
</apply>
<apply>
<eq/>
<ci>ina_m_beta</ci>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.08</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="mV">11.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_m_inf</ci>
<apply>
<divide/>
<ci>ina_m_alpha</ci>
<apply>
<plus/>
<ci>ina_m_alpha</ci>
<ci>ina_m_beta</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ina_m_tau</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<ci>ina_m_alpha</ci>
<ci>ina_m_beta</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>j</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ina_j_inf</ci>
<ci>j</ci>
</apply>
<ci>ina_j_tau</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>m</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ina_m_inf</ci>
<ci>m</ci>
</apply>
<ci>ina_m_tau</ci>
</apply>
</apply>
</math>
</component>
<component name="inab">
<variable name="ENa_jn" units="mV" public_interface="in"/>
<variable name="ENa_sl" units="mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="INaB" units="A_per_F"/>
<variable name="INaB_jn" units="A_per_F" public_interface="out"/>
<variable name="INaB_sl" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gNaB" units="mS_per_uF" initial_value="0.000597"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INaB</ci>
<apply>
<plus/>
<ci>INaB_jn</ci>
<ci>INaB_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INaB_jn</ci>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>gNaB</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ENa_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaB_sl</ci>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gNaB</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ENa_sl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="inaca">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_o" units="mM" public_interface="in"/>
<variable name="Ca_sl" units="mM" public_interface="in"/>
<variable name="FRT" units="per_mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="INaCa" units="A_per_F"/>
<variable name="INaCa_jn" units="A_per_F" public_interface="out"/>
<variable name="INaCa_sl" units="A_per_F" public_interface="out"/>
<variable name="IbarNCX" units="A_per_F"/>
<variable name="Ka_jn" units="dimensionless"/>
<variable name="Ka_sl" units="dimensionless"/>
<variable name="Kdact" units="mM" initial_value="0.000384"/>
<variable name="KmCai" units="mM" initial_value="0.00359"/>
<variable name="KmCao" units="mM" initial_value="1.3"/>
<variable name="KmNai" units="mM" initial_value="12.29"/>
<variable name="KmNao" units="mM" initial_value="87.5"/>
<variable name="Na_jn" units="mM" public_interface="in"/>
<variable name="Na_o" units="mM" public_interface="in"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<variable name="Q" units="dimensionless" public_interface="in"/>
<variable name="Q10NCX" units="dimensionless" initial_value="1.57"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="inaca_INaCa_jn_s1" units="mol4_per_m12"/>
<variable name="inaca_INaCa_jn_s2" units="mol4_per_m12"/>
<variable name="inaca_INaCa_jn_s3" units="mol4_per_m12"/>
<variable name="inaca_INaCa_sl_s1" units="mol4_per_m12"/>
<variable name="inaca_INaCa_sl_s2" units="mol4_per_m12"/>
<variable name="inaca_INaCa_sl_s3" units="mol4_per_m12"/>
<variable name="ksat" units="dimensionless" initial_value="0.27"/>
<variable name="nu" units="dimensionless" initial_value="0.35"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INaCa</ci>
<apply>
<plus/>
<ci>INaCa_jn</ci>
<ci>INaCa_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INaCa_jn</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>IbarNCX</ci>
</apply>
<apply>
<power/>
<ci>Q10NCX</ci>
<ci>Q</ci>
</apply>
</apply>
<ci>Ka_jn</ci>
</apply>
<apply>
<minus/>
<ci>inaca_INaCa_jn_s1</ci>
<ci>inaca_INaCa_jn_s2</ci>
</apply>
</apply>
<ci>inaca_INaCa_jn_s3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<ci>ksat</ci>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<apply>
<minus/>
<ci>nu</ci>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaCa_sl</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>IbarNCX</ci>
</apply>
<apply>
<power/>
<ci>Q10NCX</ci>
<ci>Q</ci>
</apply>
</apply>
<ci>Ka_sl</ci>
</apply>
<apply>
<minus/>
<ci>inaca_INaCa_sl_s1</ci>
<ci>inaca_INaCa_sl_s2</ci>
</apply>
</apply>
<ci>inaca_INaCa_sl_s3</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<ci>ksat</ci>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<apply>
<minus/>
<ci>nu</ci>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>IbarNCX</ci>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.4</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="A_per_F">3.15</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>Ka_jn</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Kdact</ci>
<ci>Ca_jn</ci>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Ka_sl</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Kdact</ci>
<ci>Ca_sl</ci>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>inaca_INaCa_jn_s1</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<ci>nu</ci>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Na_jn</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>Ca_o</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>inaca_INaCa_jn_s2</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<apply>
<minus/>
<ci>nu</ci>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>Ca_jn</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>inaca_INaCa_jn_s3</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<times/>
<ci>KmCai</ci>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Na_jn</ci>
<ci>KmNai</ci>
</apply>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<times/>
<apply>
<power/>
<ci>KmNao</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<ci>Ca_jn</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<divide/>
<ci>Ca_jn</ci>
<ci>KmCai</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>KmCao</ci>
<apply>
<power/>
<ci>Na_jn</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_jn</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<ci>Ca_o</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<ci>Ca_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>inaca_INaCa_sl_s1</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<ci>nu</ci>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Na_sl</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>Ca_o</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>inaca_INaCa_sl_s2</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<apply>
<minus/>
<ci>nu</ci>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>Ca_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>inaca_INaCa_sl_s3</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<times/>
<apply>
<times/>
<ci>KmCai</ci>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Na_sl</ci>
<ci>KmNai</ci>
</apply>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<times/>
<apply>
<power/>
<ci>KmNao</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<ci>Ca_sl</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<divide/>
<ci>Ca_sl</ci>
<ci>KmCai</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci>KmCao</ci>
<apply>
<power/>
<ci>Na_sl</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_sl</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<ci>Ca_o</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<power/>
<ci>Na_o</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<ci>Ca_sl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="inak">
<variable name="FRT" units="per_mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="INaK" units="A_per_F" public_interface="out"/>
<variable name="INaK_jn" units="A_per_F" public_interface="out"/>
<variable name="INaK_sl" units="A_per_F" public_interface="out"/>
<variable name="IbarNaK" units="A_per_F" initial_value="1.26"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="KmKo" units="mM" initial_value="1.5"/>
<variable name="KmNaip" units="mM" initial_value="11.0"/>
<variable name="Na_jn" units="mM" public_interface="in"/>
<variable name="Na_o" units="mM" public_interface="in"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="fnak" units="dimensionless"/>
<variable name="sigma" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INaK</ci>
<apply>
<plus/>
<ci>INaK_jn</ci>
<ci>INaK_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INaK_jn</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>IbarNaK</ci>
</apply>
<ci>fnak</ci>
</apply>
<ci>K_o</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>KmNaip</ci>
<ci>Na_jn</ci>
</apply>
<cn cellml:units="dimensionless">4.0</cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci>K_o</ci>
<ci>KmKo</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaK_sl</ci>
<apply>
<divide/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>IbarNaK</ci>
</apply>
<ci>fnak</ci>
</apply>
<ci>K_o</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>KmNaip</ci>
<ci>Na_sl</ci>
</apply>
<cn cellml:units="dimensionless">4.0</cn>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci>K_o</ci>
<ci>KmKo</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>fnak</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.1245</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">0.1</cn>
</apply>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<times/>
<cn cellml:units="dimensionless">0.0365</cn>
<ci>sigma</ci>
</apply>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<ci>FRT</ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>sigma</ci>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<exp/>
<apply>
<divide/>
<ci>Na_o</ci>
<cn cellml:units="mM">67.3</cn>
</apply>
</apply>
<cn cellml:units="dimensionless">1.0</cn>
</apply>
<cn cellml:units="dimensionless">7.0</cn>
</apply>
</apply>
</math>
</component>
<component name="inal">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="ENa_jn" units="mV" public_interface="in"/>
<variable name="ENa_sl" units="mV" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="INaL" units="A_per_F"/>
<variable name="INaL_jn" units="A_per_F" public_interface="out"/>
<variable name="INaL_sl" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gNaL" units="mS_per_uF"/>
<variable name="hl" units="mS_per_uF" initial_value="5.18117114324953484e-02"/>
<variable name="inal_hl_inf" units="dimensionless"/>
<variable name="inal_hl_tau" units="ms" initial_value="600.0"/>
<variable name="inal_ml_a" units="mS_per_uF"/>
<variable name="inal_ml_b" units="mS_per_uF"/>
<variable name="ml" units="mS_per_uF" initial_value="7.97426794490581868e-03"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INaL</ci>
<apply>
<plus/>
<ci>INaL_jn</ci>
<ci>INaL_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INaL_jn</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<ci>gNaL</ci>
</apply>
<apply>
<power/>
<ci>ml</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>hl</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ENa_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>INaL_sl</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<ci>gNaL</ci>
</apply>
<apply>
<power/>
<ci>ml</ci>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
</apply>
<ci>hl</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>ENa_sl</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gNaL</ci>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.0025</cn>
<ci>AF</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>hl</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>inal_hl_inf</ci>
<ci>hl</ci>
</apply>
<ci>inal_hl_tau</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>inal_hl_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">91.0</cn>
</apply>
<cn cellml:units="mV">6.1</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>inal_ml_a</ci>
<apply>
<divide/>
<apply>
<times/>
<cn cellml:units="per_mV_per_ms">0.32</cn>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">47.13</cn>
</apply>
</apply>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="per_mV">0.1</cn>
</apply>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">47.13</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>inal_ml_b</ci>
<apply>
<times/>
<cn cellml:units="mS_per_uF">0.08</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<ci>V</ci>
</apply>
<cn cellml:units="mV">11.0</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>ml</ci>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>inal_ml_a</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>ml</ci>
</apply>
</apply>
<apply>
<times/>
<ci>inal_ml_b</ci>
<ci>ml</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="ion">
<variable name="Ca_o" units="mM" public_interface="out" initial_value="1.8"/>
<variable name="Cl_i" units="mM" public_interface="out" initial_value="15.0"/>
<variable name="Cl_o" units="mM" public_interface="out" initial_value="150.0"/>
<variable name="K_o" units="mM" public_interface="out" initial_value="5.4"/>
<variable name="Mg_i" units="mM" public_interface="out" initial_value="1.0"/>
<variable name="Na_o" units="mM" public_interface="out" initial_value="140.0"/>
</component>
<component name="ipca">
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_sl" units="mM" public_interface="in"/>
<variable name="Fjn" units="dimensionless" public_interface="in"/>
<variable name="Fsl" units="dimensionless" public_interface="in"/>
<variable name="IbarSLCaP" units="A_per_F" initial_value="0.0471"/>
<variable name="IpCa" units="A_per_F"/>
<variable name="IpCa_jn" units="A_per_F" public_interface="out"/>
<variable name="IpCa_sl" units="A_per_F" public_interface="out"/>
<variable name="KmPCa" units="mM" initial_value="0.0005"/>
<variable name="Q" units="dimensionless" public_interface="in"/>
<variable name="Q10SLCaP" units="dimensionless" initial_value="2.35"/>
<variable name="b" units="dimensionless"/>
<variable name="ipca_IpCa_jn_a" units="dimensionless"/>
<variable name="ipca_IpCa_sl_a" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IpCa</ci>
<apply>
<plus/>
<ci>IpCa_jn</ci>
<ci>IpCa_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>IpCa_jn</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fjn</ci>
<apply>
<power/>
<ci>Q10SLCaP</ci>
<ci>Q</ci>
</apply>
</apply>
<ci>IbarSLCaP</ci>
</apply>
<ci>ipca_IpCa_jn_a</ci>
</apply>
<apply>
<plus/>
<ci>ipca_IpCa_jn_a</ci>
<ci>b</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>IpCa_sl</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>Fsl</ci>
<apply>
<power/>
<ci>Q10SLCaP</ci>
<ci>Q</ci>
</apply>
</apply>
<ci>IbarSLCaP</ci>
</apply>
<ci>ipca_IpCa_sl_a</ci>
</apply>
<apply>
<plus/>
<ci>ipca_IpCa_sl_a</ci>
<ci>b</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>b</ci>
<apply>
<power/>
<apply>
<times/>
<ci>KmPCa</ci>
<cn cellml:units="m3_per_mol">1.0</cn>
</apply>
<cn cellml:units="dimensionless">1.6</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ipca_IpCa_jn_a</ci>
<apply>
<power/>
<apply>
<times/>
<ci>Ca_jn</ci>
<cn cellml:units="m3_per_mol">1.0</cn>
</apply>
<cn cellml:units="dimensionless">1.6</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ipca_IpCa_sl_a</ci>
<apply>
<power/>
<apply>
<times/>
<ci>Ca_sl</ci>
<cn cellml:units="m3_per_mol">1.0</cn>
</apply>
<cn cellml:units="dimensionless">1.6</cn>
</apply>
</apply>
</math>
</component>
<component name="ito">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="EK" units="mV" public_interface="in"/>
<variable name="Ito" units="A_per_F" public_interface="out"/>
<variable name="V" units="mV" public_interface="in"/>
<variable name="gto" units="mS_per_uF"/>
<variable name="ito_x_inf" units="dimensionless"/>
<variable name="ito_x_tau" units="ms"/>
<variable name="ito_y_inf" units="dimensionless"/>
<variable name="ito_y_tau" units="ms"/>
<variable name="time" units="ms" public_interface="in"/>
<variable name="x" units="mS_per_uF" initial_value="1.19930453889315167e-03"/>
<variable name="y" units="mS_per_uF" initial_value="9.52396284498915668e-01"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Ito</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<times/>
<ci>gto</ci>
<ci>x</ci>
</apply>
<ci>y</ci>
</apply>
<apply>
<minus/>
<ci>V</ci>
<ci>EK</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>gto</ci>
<apply>
<times/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.7</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="mS_per_uF">0.165</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ito_x_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">1.0</cn>
</apply>
</apply>
<cn cellml:units="mV">11.0</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ito_x_tau</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="ms">3.5</cn>
<apply>
<exp/>
<apply>
<minus/>
<apply>
<power/>
<apply>
<divide/>
<ci>V</ci>
<cn cellml:units="mV">30.0</cn>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="ms">1.5</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>ito_y_inf</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">40.5</cn>
</apply>
<cn cellml:units="mV">11.5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ito_y_tau</ci>
<apply>
<plus/>
<apply>
<times/>
<cn cellml:units="ms">25.635</cn>
<apply>
<exp/>
<apply>
<minus/>
<apply>
<power/>
<apply>
<divide/>
<apply>
<plus/>
<ci>V</ci>
<cn cellml:units="mV">52.45</cn>
</apply>
<cn cellml:units="mV">15.8827</cn>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
</apply>
</apply>
<cn cellml:units="ms">24.14</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>x</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ito_x_inf</ci>
<ci>x</ci>
</apply>
<ci>ito_x_tau</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>y</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>ito_y_inf</ci>
<ci>y</ci>
</apply>
<ci>ito_y_tau</ci>
</apply>
</apply>
</math>
</component>
<component name="junc">
<variable name="Fjn" units="dimensionless" public_interface="out" initial_value="0.11"/>
<variable name="Fjn_CaL" units="dimensionless" public_interface="out" initial_value="0.9"/>
<variable name="Fsl" units="dimensionless" public_interface="out"/>
<variable name="Fsl_CaL" units="dimensionless" public_interface="out"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>Fsl</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Fjn</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Fsl_CaL</ci>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>Fjn_CaL</ci>
</apply>
</apply>
</math>
</component>
<component name="membrane">
<variable name="ICa_tot" units="A_per_F"/>
<variable name="ICa_tot_jn" units="A_per_F" public_interface="in"/>
<variable name="ICa_tot_sl" units="A_per_F" public_interface="in"/>
<variable name="IClB" units="A_per_F" public_interface="in"/>
<variable name="IClCa" units="A_per_F" public_interface="in"/>
<variable name="ICl_tot" units="A_per_F"/>
<variable name="IK_tot" units="A_per_F" public_interface="in"/>
<variable name="INa_tot" units="A_per_F"/>
<variable name="INa_tot_jn" units="A_per_F" public_interface="in"/>
<variable name="INa_tot_sl" units="A_per_F" public_interface="in"/>
<variable name="I_stim" units="A_per_F" public_interface="in"/>
<variable name="I_tot" units="A_per_F"/>
<variable name="V" units="mV" public_interface="out" initial_value="-7.49738877185916408e+01"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ICa_tot</ci>
<apply>
<plus/>
<ci>ICa_tot_jn</ci>
<ci>ICa_tot_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>ICl_tot</ci>
<apply>
<plus/>
<ci>IClCa</ci>
<ci>IClB</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INa_tot</ci>
<apply>
<plus/>
<ci>INa_tot_jn</ci>
<ci>INa_tot_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>I_tot</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<ci>INa_tot</ci>
<ci>ICl_tot</ci>
</apply>
<ci>ICa_tot</ci>
</apply>
<ci>IK_tot</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>V</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<ci>I_tot</ci>
<ci>I_stim</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="nernst">
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_o" units="mM" public_interface="in"/>
<variable name="Ca_sl" units="mM" public_interface="in"/>
<variable name="Cl_i" units="mM" public_interface="in"/>
<variable name="Cl_o" units="mM" public_interface="in"/>
<variable name="ECa_jn" units="mV" public_interface="out"/>
<variable name="ECa_sl" units="mV" public_interface="out"/>
<variable name="ECl" units="mV" public_interface="out"/>
<variable name="EK" units="mV" public_interface="out"/>
<variable name="ENa_jn" units="mV" public_interface="out"/>
<variable name="ENa_sl" units="mV" public_interface="out"/>
<variable name="FRT" units="per_mV" public_interface="in"/>
<variable name="K_i" units="mM" public_interface="in"/>
<variable name="K_o" units="mM" public_interface="in"/>
<variable name="Na_jn" units="mM" public_interface="in"/>
<variable name="Na_o" units="mM" public_interface="in"/>
<variable name="Na_sl" units="mM" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>ECa_jn</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Ca_o</ci>
<ci>Ca_jn</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ECa_sl</ci>
<apply>
<times/>
<apply>
<divide/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Ca_o</ci>
<ci>Ca_sl</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ECl</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Cl_i</ci>
<ci>Cl_o</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>EK</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>K_o</ci>
<ci>K_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ENa_jn</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Na_o</ci>
<ci>Na_jn</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>ENa_sl</ci>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>FRT</ci>
</apply>
<apply>
<ln/>
<apply>
<divide/>
<ci>Na_o</ci>
<ci>Na_sl</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="phys">
<variable name="F" units="C_per_mol" public_interface="out" initial_value="96485.0"/>
<variable name="FRT" units="per_mV" public_interface="out"/>
<variable name="Q" units="dimensionless" public_interface="out"/>
<variable name="R" units="mJ_per_mol_per_K" initial_value="8314.0"/>
<variable name="T" units="kelvin" initial_value="310.0"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>FRT</ci>
<apply>
<divide/>
<apply>
<divide/>
<ci>F</ci>
<ci>R</ci>
</apply>
<ci>T</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>Q</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>T</ci>
<cn cellml:units="kelvin">310.0</cn>
</apply>
<cn cellml:units="kelvin">10.0</cn>
</apply>
</apply>
</math>
</component>
<component name="potassium">
<variable name="ICaL_K" units="A_per_F" public_interface="in"/>
<variable name="IK1" units="A_per_F" public_interface="in"/>
<variable name="IKACh" units="A_per_F" public_interface="in"/>
<variable name="IK_tot" units="A_per_F" public_interface="out"/>
<variable name="IKp" units="A_per_F" public_interface="in"/>
<variable name="IKr" units="A_per_F" public_interface="in"/>
<variable name="IKs" units="A_per_F" public_interface="in"/>
<variable name="IKur" units="A_per_F" public_interface="in"/>
<variable name="INaK" units="A_per_F" public_interface="in"/>
<variable name="Ito" units="A_per_F" public_interface="in"/>
<variable name="K_i" units="mM" public_interface="out" initial_value="120.0"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>IK_tot</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<ci>Ito</ci>
<ci>IKr</ci>
</apply>
<ci>IKs</ci>
</apply>
<ci>IK1</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">2.0</cn>
<ci>INaK</ci>
</apply>
</apply>
<ci>ICaL_K</ci>
</apply>
<ci>IKp</ci>
</apply>
<ci>IKur</ci>
</apply>
<ci>IKACh</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>K_i</ci>
</apply>
<cn cellml:units="mM_per_ms">0.0</cn>
</apply>
</math>
</component>
<component name="ryr">
<variable name="AF" units="dimensionless" public_interface="in"/>
<variable name="Ca_i" units="mM" public_interface="in"/>
<variable name="Ca_jn" units="mM" public_interface="in"/>
<variable name="Ca_sr" units="mM" public_interface="in"/>
<variable name="J_SRCarel" units="mM_per_ms" public_interface="out"/>
<variable name="J_SRleak" units="mM_per_ms" public_interface="out"/>
<variable name="J_serca" units="mM_per_ms" public_interface="out"/>
<variable name="Kmf" units="mM"/>
<variable name="Kmr" units="mM" initial_value="1.7"/>
<variable name="MaxSR" units="dimensionless" initial_value="15.0"/>
<variable name="MinSR" units="dimensionless" initial_value="1.0"/>
<variable name="Q" units="dimensionless" public_interface="in"/>
<variable name="Q10SRCaP" units="dimensionless" initial_value="2.6"/>
<variable name="RI" units="dimensionless"/>
<variable name="Vmax_SRCaP" units="mM_per_ms" initial_value="0.0053114"/>
<variable name="ec50SR" units="mM" initial_value="0.45"/>
<variable name="hillSRCaP" units="dimensionless" initial_value="1.787"/>
<variable name="i" units="mS_per_uF" initial_value="4.16351235655844508e-07"/>
<variable name="kCaSR" units="dimensionless"/>
<variable name="kiCa" units="per_mM_per_ms" initial_value="0.5"/>
<variable name="kiSRCa" units="per_mM_per_ms"/>
<variable name="kim" units="mS_per_uF" initial_value="0.005"/>
<variable name="koCa" units="per_mM2_per_ms"/>
<variable name="koSRCa" units="per_mM2_per_ms"/>
<variable name="kom" units="mS_per_uF" initial_value="0.06"/>
<variable name="ks" units="mS_per_uF" initial_value="25.0"/>
<variable name="o" units="mS_per_uF" initial_value="1.73377710603823675e-06"/>
<variable name="r" units="mS_per_uF" initial_value="8.06359263514647706e-01"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>J_SRCarel</ci>
<apply>
<times/>
<apply>
<times/>
<ci>ks</ci>
<ci>o</ci>
</apply>
<apply>
<minus/>
<ci>Ca_sr</ci>
<ci>Ca_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>J_SRleak</ci>
<apply>
<times/>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">0.25</cn>
<ci>AF</ci>
</apply>
</apply>
<apply>
<minus/>
<ci>Ca_sr</ci>
<ci>Ca_jn</ci>
</apply>
</apply>
<cn cellml:units="mS_per_uF">5.348e-06</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>J_serca</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<times/>
<apply>
<power/>
<ci>Q10SRCaP</ci>
<ci>Q</ci>
</apply>
<ci>Vmax_SRCaP</ci>
</apply>
<apply>
<minus/>
<apply>
<power/>
<apply>
<divide/>
<ci>Ca_i</ci>
<ci>Kmf</ci>
</apply>
<ci>hillSRCaP</ci>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>Ca_sr</ci>
<ci>Kmr</ci>
</apply>
<ci>hillSRCaP</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>Ca_i</ci>
<ci>Kmf</ci>
</apply>
<ci>hillSRCaP</ci>
</apply>
</apply>
<apply>
<power/>
<apply>
<divide/>
<ci>Ca_sr</ci>
<ci>Kmr</ci>
</apply>
<ci>hillSRCaP</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>Kmf</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">2.5</cn>
<cn cellml:units="mM">0.000246</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>RI</ci>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<cn cellml:units="dimensionless">1.0</cn>
<ci>r</ci>
</apply>
<ci>o</ci>
</apply>
<ci>i</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>i</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kiSRCa</ci>
<ci>Ca_jn</ci>
</apply>
<ci>o</ci>
</apply>
<apply>
<times/>
<ci>kim</ci>
<ci>i</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<ci>kom</ci>
<ci>i</ci>
</apply>
<apply>
<times/>
<apply>
<times/>
<ci>koSRCa</ci>
<apply>
<power/>
<ci>Ca_jn</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
<ci>RI</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>kCaSR</ci>
<apply>
<minus/>
<ci>MaxSR</ci>
<apply>
<divide/>
<apply>
<minus/>
<ci>MaxSR</ci>
<ci>MinSR</ci>
</apply>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<power/>
<apply>
<divide/>
<ci>ec50SR</ci>
<ci>Ca_sr</ci>
</apply>
<cn cellml:units="dimensionless">2.5</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>kiSRCa</ci>
<apply>
<times/>
<ci>kiCa</ci>
<ci>kCaSR</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>koCa</ci>
<apply>
<times/>
<apply>
<plus/>
<cn cellml:units="dimensionless">10.0</cn>
<apply>
<times/>
<cn cellml:units="dimensionless">20.0</cn>
<ci>AF</ci>
</apply>
</apply>
<cn cellml:units="per_mM2_per_ms">1.0</cn>
</apply>
</apply>
<apply>
<eq/>
<ci>koSRCa</ci>
<apply>
<divide/>
<ci>koCa</ci>
<ci>kCaSR</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>o</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>koSRCa</ci>
<apply>
<power/>
<ci>Ca_jn</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
<ci>r</ci>
</apply>
<apply>
<times/>
<ci>kom</ci>
<ci>o</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>kiSRCa</ci>
<ci>Ca_jn</ci>
</apply>
<ci>o</ci>
</apply>
<apply>
<times/>
<ci>kim</ci>
<ci>i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>r</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>kim</ci>
<ci>RI</ci>
</apply>
<apply>
<times/>
<apply>
<times/>
<ci>kiSRCa</ci>
<ci>Ca_jn</ci>
</apply>
<ci>r</ci>
</apply>
</apply>
<apply>
<minus/>
<apply>
<times/>
<apply>
<times/>
<ci>koSRCa</ci>
<apply>
<power/>
<ci>Ca_jn</ci>
<cn cellml:units="dimensionless">2.0</cn>
</apply>
</apply>
<ci>r</ci>
</apply>
<apply>
<times/>
<ci>kom</ci>
<ci>o</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
<component name="sodium">
<variable name="C" units="farad" public_interface="in"/>
<variable name="F" units="C_per_mol" public_interface="in"/>
<variable name="ICaL_Na_jn" units="A_per_F" public_interface="in"/>
<variable name="ICaL_Na_sl" units="A_per_F" public_interface="in"/>
<variable name="INaB_jn" units="A_per_F" public_interface="in"/>
<variable name="INaB_sl" units="A_per_F" public_interface="in"/>
<variable name="INaCa_jn" units="A_per_F" public_interface="in"/>
<variable name="INaCa_sl" units="A_per_F" public_interface="in"/>
<variable name="INaK_jn" units="A_per_F" public_interface="in"/>
<variable name="INaK_sl" units="A_per_F" public_interface="in"/>
<variable name="INaL_jn" units="A_per_F" public_interface="in"/>
<variable name="INaL_sl" units="A_per_F" public_interface="in"/>
<variable name="INa_jn" units="A_per_F" public_interface="in"/>
<variable name="INa_sl" units="A_per_F" public_interface="in"/>
<variable name="INa_tot_jn" units="A_per_F" public_interface="out"/>
<variable name="INa_tot_sl" units="A_per_F" public_interface="out"/>
<variable name="JNa_jnsl" units="m3_per_s"/>
<variable name="JNa_slmyo" units="m3_per_s"/>
<variable name="NaB_jn" units="mM" public_interface="in"/>
<variable name="NaB_sl" units="mM" public_interface="in"/>
<variable name="Na_i" units="mM" public_interface="out" initial_value="9.20582356442186978e+00"/>
<variable name="Na_jn" units="mM" public_interface="out" initial_value="9.20484970072274145e+00"/>
<variable name="Na_sl" units="mM" public_interface="out" initial_value="9.20559631626608166e+00"/>
<variable name="Vjn" units="litre" public_interface="in"/>
<variable name="Vmyo" units="litre" public_interface="in"/>
<variable name="Vsl" units="litre" public_interface="in"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>INa_tot_jn</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<ci>INa_jn</ci>
<ci>INaB_jn</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3.0</cn>
<ci>INaCa_jn</ci>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3.0</cn>
<ci>INaK_jn</ci>
</apply>
</apply>
<ci>ICaL_Na_jn</ci>
</apply>
<ci>INaL_jn</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>INa_tot_sl</ci>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<plus/>
<ci>INa_sl</ci>
<ci>INaB_sl</ci>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3.0</cn>
<ci>INaCa_sl</ci>
</apply>
</apply>
<apply>
<times/>
<cn cellml:units="dimensionless">3.0</cn>
<ci>INaK_sl</ci>
</apply>
</apply>
<ci>ICaL_Na_sl</ci>
</apply>
<ci>INaL_sl</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>JNa_jnsl</ci>
<apply>
<divide/>
<cn cellml:units="m3_per_s">1.0</cn>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless"> 1.63820000000000000e+12</cn>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<cn cellml:units="dimensionless">100.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>JNa_slmyo</ci>
<apply>
<divide/>
<cn cellml:units="m3_per_s">1.0</cn>
<apply>
<times/>
<apply>
<divide/>
<cn cellml:units="dimensionless"> 1.83080000000000000e+10</cn>
<cn cellml:units="dimensionless">3.0</cn>
</apply>
<cn cellml:units="dimensionless">100.0</cn>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Na_i</ci>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JNa_slmyo</ci>
<ci>Vmyo</ci>
</apply>
<apply>
<minus/>
<ci>Na_sl</ci>
<ci>Na_i</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Na_jn</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>INa_tot_jn</ci>
</apply>
<ci>C</ci>
</apply>
<apply>
<times/>
<ci>Vjn</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JNa_jnsl</ci>
<ci>Vjn</ci>
</apply>
<apply>
<minus/>
<ci>Na_sl</ci>
<ci>Na_jn</ci>
</apply>
</apply>
</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>NaB_jn</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>Na_sl</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<plus/>
<apply>
<divide/>
<apply>
<times/>
<apply>
<minus/>
<ci>INa_tot_sl</ci>
</apply>
<ci>C</ci>
</apply>
<apply>
<times/>
<ci>Vsl</ci>
<ci>F</ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JNa_jnsl</ci>
<ci>Vsl</ci>
</apply>
<apply>
<minus/>
<ci>Na_jn</ci>
<ci>Na_sl</ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<divide/>
<ci>JNa_slmyo</ci>
<ci>Vsl</ci>
</apply>
<apply>
<minus/>
<ci>Na_i</ci>
<ci>Na_sl</ci>
</apply>
</apply>
</apply>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>NaB_sl</ci>
</apply>
</apply>
</apply>
</math>
</component>
<component name="stimulus">
<variable name="I_stim" units="A_per_F" public_interface="out"/>
<variable name="amplitude" units="A_per_F" cmeta:id="amplitude"/>
<variable name="duration" units="ms" initial_value="0.5" cmeta:id="duration"/>
<variable name="offset" units="ms" initial_value="50.0" cmeta:id="offset"/>
<variable name="period" units="ms" initial_value="1000.0" cmeta:id="period"/>
<variable name="time" units="ms" public_interface="in"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>I_stim</ci>
<apply>
<times/>
<piecewise>
<piece>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<lt/>
<apply>
<minus/>
<apply>
<minus/>
<ci>time</ci>
<ci>offset</ci>
</apply>
<apply>
<times/>
<ci>period</ci>
<apply>
<floor/>
<apply>
<divide/>
<apply>
<minus/>
<ci>time</ci>
<ci>offset</ci>
</apply>
<ci>period</ci>
</apply>
</apply>
</apply>
</apply>
<ci>duration</ci>
</apply>
</piece>
<otherwise>
<cn cellml:units="dimensionless">0.0</cn>
</otherwise>
</piecewise>
<ci>amplitude</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>amplitude</ci>
<apply>
<minus/>
<cn cellml:units="A_per_F">90.0</cn>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="buffca" component_2="calcium"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sl" variable_2="Ca_sl"/>
<map_variables variable_1="J_CaB_cytosol" variable_2="J_CaB_cytosol"/>
<map_variables variable_1="J_CaB_jn" variable_2="J_CaB_jn"/>
<map_variables variable_1="J_CaB_sl" variable_2="J_CaB_sl"/>
</connection>
<connection>
<map_components component_1="buffca" component_2="engine"/>
<map_variables variable_1="CaM" variable_2="CaM"/>
<map_variables variable_1="Myoc" variable_2="Myoc"/>
<map_variables variable_1="Myom" variable_2="Myom"/>
<map_variables variable_1="SLH_jn" variable_2="SLH_jn"/>
<map_variables variable_1="SLH_sl" variable_2="SLH_sl"/>
<map_variables variable_1="SLL_jn" variable_2="SLL_jn"/>
<map_variables variable_1="SLL_sl" variable_2="SLL_sl"/>
<map_variables variable_1="SRB" variable_2="SRB"/>
<map_variables variable_1="TnCHc" variable_2="TnCHc"/>
<map_variables variable_1="TnCHm" variable_2="TnCHm"/>
<map_variables variable_1="TnCL" variable_2="TnCL"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="buffca" component_2="geom"/>
<map_variables variable_1="Vjn" variable_2="Vjn"/>
<map_variables variable_1="Vmyo" variable_2="Vmyo"/>
<map_variables variable_1="Vsl" variable_2="Vsl"/>
</connection>
<connection>
<map_components component_1="buffca" component_2="ion"/>
<map_variables variable_1="Mg_i" variable_2="Mg_i"/>
</connection>
<connection>
<map_components component_1="buffna" component_2="engine"/>
<map_variables variable_1="NaB_jn" variable_2="NaB_jn"/>
<map_variables variable_1="NaB_sl" variable_2="NaB_sl"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="buffna" component_2="sodium"/>
<map_variables variable_1="NaB_jn" variable_2="NaB_jn"/>
<map_variables variable_1="NaB_sl" variable_2="NaB_sl"/>
<map_variables variable_1="Na_jn" variable_2="Na_jn"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="cell"/>
<map_variables variable_1="C" variable_2="C"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="engine"/>
<map_variables variable_1="Csqn" variable_2="Csqn"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="geom"/>
<map_variables variable_1="Vjn" variable_2="Vjn"/>
<map_variables variable_1="Vmyo" variable_2="Vmyo"/>
<map_variables variable_1="Vsl" variable_2="Vsl"/>
<map_variables variable_1="Vsr" variable_2="Vsr"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="icab"/>
<map_variables variable_1="ICaB_jn" variable_2="ICaB_jn"/>
<map_variables variable_1="ICaB_sl" variable_2="ICaB_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="ical"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sl" variable_2="Ca_sl"/>
<map_variables variable_1="ICaL_Ca_jn" variable_2="ICaL_Ca_jn"/>
<map_variables variable_1="ICaL_Ca_sl" variable_2="ICaL_Ca_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="iclca"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sl" variable_2="Ca_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="inaca"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sl" variable_2="Ca_sl"/>
<map_variables variable_1="INaCa_jn" variable_2="INaCa_jn"/>
<map_variables variable_1="INaCa_sl" variable_2="INaCa_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="ipca"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sl" variable_2="Ca_sl"/>
<map_variables variable_1="IpCa_jn" variable_2="IpCa_jn"/>
<map_variables variable_1="IpCa_sl" variable_2="IpCa_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="membrane"/>
<map_variables variable_1="ICa_tot_jn" variable_2="ICa_tot_jn"/>
<map_variables variable_1="ICa_tot_sl" variable_2="ICa_tot_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="nernst"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sl" variable_2="Ca_sl"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="phys"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<connection>
<map_components component_1="calcium" component_2="ryr"/>
<map_variables variable_1="Ca_i" variable_2="Ca_i"/>
<map_variables variable_1="Ca_jn" variable_2="Ca_jn"/>
<map_variables variable_1="Ca_sr" variable_2="Ca_sr"/>
<map_variables variable_1="J_SRCarel" variable_2="J_SRCarel"/>
<map_variables variable_1="J_SRleak" variable_2="J_SRleak"/>
<map_variables variable_1="J_serca" variable_2="J_serca"/>
</connection>
<connection>
<map_components component_1="cell" component_2="ical"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="ik1"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="ikach"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="iks"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="ikur"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="inaca"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="inal"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="ito"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="ryr"/>
<map_variables variable_1="AF" variable_2="AF"/>
</connection>
<connection>
<map_components component_1="cell" component_2="sodium"/>
<map_variables variable_1="C" variable_2="C"/>
</connection>
<connection>
<map_components component_1="engine" component_2="ical"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="ikr"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="iks"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="ikur"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="ina"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="inal"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="ito"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="membrane"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="potassium"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="ryr"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="sodium"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="engine" component_2="stimulus"/>
<map_variables variable_1="time" variable_2="time"/>
</connection>
<connection>
<map_components component_1="geom" component_2="sodium"/>
<map_variables variable_1="Vjn" variable_2="Vjn"/>
<map_variables variable_1="Vmyo" variable_2="Vmyo"/>
<map_variables variable_1="Vsl" variable_2="Vsl"/>
</connection>
<connection>
<map_components component_1="icab" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="icab" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="icab" component_2="nernst"/>
<map_variables variable_1="ECa_jn" variable_2="ECa_jn"/>
<map_variables variable_1="ECa_sl" variable_2="ECa_sl"/>
</connection>
<connection>
<map_components component_1="ical" component_2="ion"/>
<map_variables variable_1="Ca_o" variable_2="Ca_o"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="ical" component_2="junc"/>
<map_variables variable_1="Fjn_CaL" variable_2="Fjn_CaL"/>
<map_variables variable_1="Fsl_CaL" variable_2="Fsl_CaL"/>
</connection>
<connection>
<map_components component_1="ical" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ical" component_2="phys"/>
<map_variables variable_1="F" variable_2="F"/>
<map_variables variable_1="FRT" variable_2="FRT"/>
<map_variables variable_1="Q" variable_2="Q"/>
</connection>
<connection>
<map_components component_1="ical" component_2="potassium"/>
<map_variables variable_1="ICaL_K" variable_2="ICaL_K"/>
<map_variables variable_1="K_i" variable_2="K_i"/>
</connection>
<connection>
<map_components component_1="ical" component_2="sodium"/>
<map_variables variable_1="ICaL_Na_jn" variable_2="ICaL_Na_jn"/>
<map_variables variable_1="ICaL_Na_sl" variable_2="ICaL_Na_sl"/>
<map_variables variable_1="Na_jn" variable_2="Na_jn"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="iclb" component_2="membrane"/>
<map_variables variable_1="IClB" variable_2="IClB"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="iclb" component_2="nernst"/>
<map_variables variable_1="ECl" variable_2="ECl"/>
</connection>
<connection>
<map_components component_1="iclca" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="iclca" component_2="membrane"/>
<map_variables variable_1="IClCa" variable_2="IClCa"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="iclca" component_2="nernst"/>
<map_variables variable_1="ECl" variable_2="ECl"/>
</connection>
<connection>
<map_components component_1="ik1" component_2="ion"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
</connection>
<connection>
<map_components component_1="ik1" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ik1" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="ik1" component_2="potassium"/>
<map_variables variable_1="IK1" variable_2="IK1"/>
</connection>
<connection>
<map_components component_1="ik1" component_2="sodium"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="ikach" component_2="ion"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
</connection>
<connection>
<map_components component_1="ikach" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ikach" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="ikach" component_2="potassium"/>
<map_variables variable_1="IKACh" variable_2="IKACh"/>
</connection>
<connection>
<map_components component_1="ikach" component_2="sodium"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="ikp" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="ikp" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ikp" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="ikp" component_2="potassium"/>
<map_variables variable_1="IKp" variable_2="IKp"/>
</connection>
<connection>
<map_components component_1="ikr" component_2="ion"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
</connection>
<connection>
<map_components component_1="ikr" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ikr" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="ikr" component_2="potassium"/>
<map_variables variable_1="IKr" variable_2="IKr"/>
</connection>
<connection>
<map_components component_1="iks" component_2="ion"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="iks" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="iks" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="iks" component_2="phys"/>
<map_variables variable_1="FRT" variable_2="FRT"/>
</connection>
<connection>
<map_components component_1="iks" component_2="potassium"/>
<map_variables variable_1="IKs" variable_2="IKs"/>
<map_variables variable_1="K_i" variable_2="K_i"/>
</connection>
<connection>
<map_components component_1="iks" component_2="sodium"/>
<map_variables variable_1="Na_i" variable_2="Na_i"/>
</connection>
<connection>
<map_components component_1="ikur" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ikur" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="ikur" component_2="potassium"/>
<map_variables variable_1="IKur" variable_2="IKur"/>
</connection>
<connection>
<map_components component_1="ina" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="ina" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ina" component_2="nernst"/>
<map_variables variable_1="ENa_jn" variable_2="ENa_jn"/>
<map_variables variable_1="ENa_sl" variable_2="ENa_sl"/>
</connection>
<connection>
<map_components component_1="ina" component_2="sodium"/>
<map_variables variable_1="INa_jn" variable_2="INa_jn"/>
<map_variables variable_1="INa_sl" variable_2="INa_sl"/>
</connection>
<connection>
<map_components component_1="inab" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="inab" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="inab" component_2="nernst"/>
<map_variables variable_1="ENa_jn" variable_2="ENa_jn"/>
<map_variables variable_1="ENa_sl" variable_2="ENa_sl"/>
</connection>
<connection>
<map_components component_1="inab" component_2="sodium"/>
<map_variables variable_1="INaB_jn" variable_2="INaB_jn"/>
<map_variables variable_1="INaB_sl" variable_2="INaB_sl"/>
</connection>
<connection>
<map_components component_1="inaca" component_2="ion"/>
<map_variables variable_1="Ca_o" variable_2="Ca_o"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="inaca" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="inaca" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="inaca" component_2="phys"/>
<map_variables variable_1="FRT" variable_2="FRT"/>
<map_variables variable_1="Q" variable_2="Q"/>
</connection>
<connection>
<map_components component_1="inaca" component_2="sodium"/>
<map_variables variable_1="INaCa_jn" variable_2="INaCa_jn"/>
<map_variables variable_1="INaCa_sl" variable_2="INaCa_sl"/>
<map_variables variable_1="Na_jn" variable_2="Na_jn"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="inak" component_2="ion"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="inak" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="inak" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="inak" component_2="phys"/>
<map_variables variable_1="FRT" variable_2="FRT"/>
</connection>
<connection>
<map_components component_1="inak" component_2="potassium"/>
<map_variables variable_1="INaK" variable_2="INaK"/>
</connection>
<connection>
<map_components component_1="inak" component_2="sodium"/>
<map_variables variable_1="INaK_jn" variable_2="INaK_jn"/>
<map_variables variable_1="INaK_sl" variable_2="INaK_sl"/>
<map_variables variable_1="Na_jn" variable_2="Na_jn"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="inal" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="inal" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="inal" component_2="nernst"/>
<map_variables variable_1="ENa_jn" variable_2="ENa_jn"/>
<map_variables variable_1="ENa_sl" variable_2="ENa_sl"/>
</connection>
<connection>
<map_components component_1="inal" component_2="sodium"/>
<map_variables variable_1="INaL_jn" variable_2="INaL_jn"/>
<map_variables variable_1="INaL_sl" variable_2="INaL_sl"/>
</connection>
<connection>
<map_components component_1="ion" component_2="nernst"/>
<map_variables variable_1="Ca_o" variable_2="Ca_o"/>
<map_variables variable_1="Cl_i" variable_2="Cl_i"/>
<map_variables variable_1="Cl_o" variable_2="Cl_o"/>
<map_variables variable_1="K_o" variable_2="K_o"/>
<map_variables variable_1="Na_o" variable_2="Na_o"/>
</connection>
<connection>
<map_components component_1="ipca" component_2="junc"/>
<map_variables variable_1="Fjn" variable_2="Fjn"/>
<map_variables variable_1="Fsl" variable_2="Fsl"/>
</connection>
<connection>
<map_components component_1="ipca" component_2="phys"/>
<map_variables variable_1="Q" variable_2="Q"/>
</connection>
<connection>
<map_components component_1="ito" component_2="membrane"/>
<map_variables variable_1="V" variable_2="V"/>
</connection>
<connection>
<map_components component_1="ito" component_2="nernst"/>
<map_variables variable_1="EK" variable_2="EK"/>
</connection>
<connection>
<map_components component_1="ito" component_2="potassium"/>
<map_variables variable_1="Ito" variable_2="Ito"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="potassium"/>
<map_variables variable_1="IK_tot" variable_2="IK_tot"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="sodium"/>
<map_variables variable_1="INa_tot_jn" variable_2="INa_tot_jn"/>
<map_variables variable_1="INa_tot_sl" variable_2="INa_tot_sl"/>
</connection>
<connection>
<map_components component_1="membrane" component_2="stimulus"/>
<map_variables variable_1="I_stim" variable_2="I_stim"/>
</connection>
<connection>
<map_components component_1="nernst" component_2="phys"/>
<map_variables variable_1="FRT" variable_2="FRT"/>
</connection>
<connection>
<map_components component_1="nernst" component_2="potassium"/>
<map_variables variable_1="K_i" variable_2="K_i"/>
</connection>
<connection>
<map_components component_1="nernst" component_2="sodium"/>
<map_variables variable_1="Na_jn" variable_2="Na_jn"/>
<map_variables variable_1="Na_sl" variable_2="Na_sl"/>
</connection>
<connection>
<map_components component_1="phys" component_2="ryr"/>
<map_variables variable_1="Q" variable_2="Q"/>
</connection>
<connection>
<map_components component_1="phys" component_2="sodium"/>
<map_variables variable_1="F" variable_2="F"/>
</connection>
<rdf:RDF>
<rdf:Description rdf:about="#amplitude">
<bqbiol:is rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_stimulus_current_amplitude"/>
</rdf:Description>
<rdf:Description rdf:about="#duration">
<bqbiol:is rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_stimulus_current_duration"/>
</rdf:Description>
<rdf:Description rdf:about="#offset">
<bqbiol:is rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_stimulus_current_offset"/>
</rdf:Description>
<rdf:Description rdf:about="#period">
<bqbiol:is rdf:resource="https://chaste.comlab.ox.ac.uk/cellml/ns/oxford-metadata#membrane_stimulus_current_period"/>
</rdf:Description>
<rdf:Description rdf:about="#voigt_heijman_2013">
<bqs:reference rdf:parseType="Resource">
<dc:subject rdf:parseType="Resource">
<bqs:subject_type>keyword</bqs:subject_type>
<rdf:value>
<rdf:Bag>
<rdf:li>electrophysiology</rdf:li>
</rdf:Bag>
</rdf:value>
</dc:subject>
</bqs:reference>
</rdf:Description>
</rdf:RDF>
</model>
