<?xml version='1.0' encoding='UTF-8'?>
<model name="BG6" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#">
<!-- Enzyme catalyzed reaction (kinetic, SS reduced & MM)-->
<units name="mol_per_s">
<unit units="mole"/>
<unit exponent="-1" units="second"/>
</units>
<units name="per_mol">
<unit exponent="-1" units="mole"/>
</units>
<component name="main">
<variable initial_value="0" name="t" units="second"/>
<!-- State variables & flux variables-->
<variable initial_value="30" name="q_1" units="mole"/>
<variable initial_value="0" name="q_2" units="mole"/>
<variable initial_value="10" name="q_3" units="mole"/>
<variable initial_value="0" name="q_4" units="mole"/>
<variable name="v_1" units="mol_per_s"/>
<variable name="v_2" units="mol_per_s"/>
<variable name="v_SS" units="mol_per_s"/>
<variable name="v_MM" units="mol_per_s"/>
<!-- Constitutive parameters-->
<variable initial_value="0.1" name="K_1" units="per_mol"/>
<variable initial_value="0.1" name="K_2" units="per_mol"/>
<variable initial_value="0.1" name="K_3" units="per_mol"/>
<variable initial_value="0.1" name="K_4" units="per_mol"/>
<variable initial_value="10" name="kappa_1" units="mol_per_s"/>
<variable initial_value="10" name="kappa_2" units="mol_per_s"/>
<variable name="E_0" units="mole"/>
<variable name="k_m" units="mole"/>
<variable name="v_max" units="mol_per_s"/>
<!-- Conservation laws-->
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>E_0</ci>
<apply>
<plus/>
<ci>q_3</ci>
<ci>q_4</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_1</ci>
</apply>
<apply>
<minus/>
<ci>v_1</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_2</ci>
</apply>
<ci>v_2</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_3</ci>
</apply>
<apply>
<minus/>
<ci>v_2</ci>
<ci>v_1</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_4</ci>
</apply>
<apply>
<minus/>
<ci>v_1</ci>
<ci>v_2</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_1</ci>
<apply>
<times/>
<ci>kappa_1</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_1</ci>
<ci>q_1</ci>
<ci>K_3</ci>
<ci>q_3</ci>
</apply>
<apply>
<times/>
<ci>K_4</ci>
<ci>q_4</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_2</ci>
<apply>
<times/>
<ci>kappa_2</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_4</ci>
<ci>q_4</ci>
</apply>
<apply>
<times/>
<ci>K_2</ci>
<ci>q_2</ci>
<ci>K_3</ci>
<ci>q_3</ci>
</apply>
</apply>
</apply>
</apply>
<!-- Reduced models (SS & MM) -->
<apply>
<eq/>
<ci>v_SS</ci>
<apply>
<divide/>
<apply>
<times/>
<ci>E_0</ci>
<ci>kappa_1</ci>
<ci>kappa_2</ci>
<ci>K_3</ci>
<ci>K_4</ci>
<apply>
<minus/>
<apply>
<times/>
<ci>K_1</ci>
<ci>q_1</ci>
</apply>
<apply>
<times/>
<ci>K_2</ci>
<ci>q_2</ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci>K_4</ci>
<apply>
<plus/>
<ci>kappa_1</ci>
<ci>kappa_2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>kappa_1</ci>
<ci>K_1</ci>
<ci>K_3</ci>
<ci>q_1</ci>
</apply>
<apply>
<times/>
<ci>kappa_2</ci>
<ci>K_2</ci>
<ci>K_3</ci>
<ci>q_2</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_max</ci>
<apply>
<times/>
<ci>E_0</ci>
<ci>kappa_2</ci>
<ci>K_4</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k_m</ci>
<apply>
<divide/>
<apply>
<times/>
<apply>
<plus/>
<ci>kappa_1</ci>
<ci>kappa_2</ci>
</apply>
<ci>K_4</ci>
</apply>
<apply>
<times/>
<ci>kappa_1</ci>
<ci>K_1</ci>
<ci>K_3</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>v_MM</ci>
<apply>
<times/>
<ci>v_max</ci>
<apply>
<divide/>
<ci>q_1</ci>
<apply>
<plus/>
<ci>k_m</ci>
<ci>q_1</ci>
</apply>
</apply>
</apply>
</apply>
</math>
</component>
</model>