Gee_whiz_Exported.cellml

Introduction

In this exposure we provide the CellML model and associated SED-ML to demonstrate the use of in-browser simulation via the SPARC Portal. The full content of the workspace is described below, but for this demonstration we collect the entire mathematical model in a single CellML file with an associated SED-ML for the simulation description. The COMBINE Archive available from the button to the right contains the single CellML and SED-ML documents to be used in this demonstration.

Workspace

This workspace illustrates how to connect multiscale models using the bond graph formalism.

The main CellML files in folder models are:

• Cardiovascular model encodes a cardiovascular system simplified from Gee, Michelle M., et al.(2023). The model follows the bond graph formalism.
• Neural control model encodes the neural control mechanism described in Gee, Michelle M., et al.(2023).
• Cell action potential model encodes the M cell action potential model described in ten Tusscher et al. (2004)
• Combined model connects the M cell action potential model to the cardiovascular model via the tension model described in HMT 1998
• the folder CellMLV2 includes the flattened combined model using CellML version 2 and the associated SED-ML file.