Generated Code
The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)
The raw code is available.
/*
There are a total of 27 entries in the algebraic variable array.
There are a total of 11 entries in each of the rate and state variable arrays.
There are a total of 48 entries in the constant variable array.
*/
/*
* VOI is time in component environment (millisecond).
* CONSTANTS[0] is isotonic_mode in component parameters (dimensionless).
* CONSTANTS[1] is alpha_1 in component parameters (per_um).
* CONSTANTS[2] is beta_1 in component parameters (mN).
* CONSTANTS[3] is alpha_2 in component parameters (per_um).
* CONSTANTS[4] is beta_2 in component parameters (mN).
* CONSTANTS[5] is alpha_3 in component parameters (per_um).
* CONSTANTS[6] is beta_3 in component parameters (mN).
* CONSTANTS[7] is lambda in component parameters (mN).
* CONSTANTS[8] is A_half in component parameters (dimensionless).
* CONSTANTS[9] is mu in component parameters (dimensionless).
* CONSTANTS[10] is chi in component parameters (dimensionless).
* CONSTANTS[11] is chi_0 in component parameters (dimensionless).
* CONSTANTS[12] is m_0 in component parameters (dimensionless).
* CONSTANTS[13] is v_max in component parameters (um_per_msec).
* CONSTANTS[14] is a in component parameters (dimensionless).
* CONSTANTS[15] is d_h in component parameters (dimensionless).
* CONSTANTS[16] is alpha_P in component parameters (dimensionless).
* CONSTANTS[17] is alpha_PG in component parameters (dimensionless).
* CONSTANTS[18] is S_0 in component parameters_izakov_et_al_1991 (um).
* ALGEBRAIC[0] is q_v in component parameters_izakov_et_al_1991 (per_millisecond).
* CONSTANTS[19] is q_1 in component parameters_izakov_et_al_1991 (per_millisecond).
* CONSTANTS[20] is q_2 in component parameters_izakov_et_al_1991 (per_millisecond).
* CONSTANTS[21] is q_3 in component parameters_izakov_et_al_1991 (per_millisecond).
* CONSTANTS[45] is v_1 in component parameters_izakov_et_al_1991 (um_per_msec).
* CONSTANTS[22] is alpha_P in component parameters_izakov_et_al_1991 (per_um).
* CONSTANTS[23] is alpha_S in component parameters_izakov_et_al_1991 (per_um).
* CONSTANTS[24] is alpha_G in component parameters_izakov_et_al_1991 (dimensionless).
* CONSTANTS[25] is a_on in component parameters_izakov_et_al_1991 (per_millisecond).
* CONSTANTS[26] is a_off in component parameters_izakov_et_al_1991 (per_millisecond).
* CONSTANTS[27] is k_A in component parameters_izakov_et_al_1991 (dimensionless).
* STATES[0] is v in component CE_velocity (um_per_msec).
* ALGEBRAIC[21] is F_CE in component force (mN).
* ALGEBRAIC[22] is F_muscle in component force (mN).
* ALGEBRAIC[3] is F_XSE in component force (mN).
* ALGEBRAIC[1] is F_SE in component force (mN).
* ALGEBRAIC[2] is F_PE in component force (mN).
* STATES[1] is N in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[10] is k_P_vis in component CE_velocity (mN).
* ALGEBRAIC[11] is k_S_vis in component PE_velocity (mN).
* STATES[2] is w in component PE_velocity (um_per_msec).
* STATES[3] is l_1 in component length (um).
* STATES[4] is l_2 in component length (um).
* STATES[5] is l_3 in component length (um).
* ALGEBRAIC[17] is p_v in component average_crossbridge_force (dimensionless).
* ALGEBRAIC[25] is K_chi in component crossbridge_kinetics (per_millisecond).
* ALGEBRAIC[4] is M_A in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[5] is n_1 in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[6] is L_oz in component crossbridge_kinetics (dimensionless).
* ALGEBRAIC[23] is k_p_v in component crossbridge_kinetics (per_millisecond).
* ALGEBRAIC[24] is k_m_v in component crossbridge_kinetics (per_millisecond).
* STATES[6] is A in component calcium_handling (dimensionless).
* ALGEBRAIC[14] is G_star in component average_crossbridge_force (dimensionless).
* ALGEBRAIC[7] is dl_1_dt in component length (um_per_msec).
* ALGEBRAIC[8] is dl_2_dt in component length (um_per_msec).
* ALGEBRAIC[9] is dl_3_dt in component length (um_per_msec).
* STATES[9] is phi_chi in component CE_velocity (um_per_msec2).
* STATES[10] is p_prime_v in component average_crossbridge_force (per_millisecond).
* CONSTANTS[28] is alpha_P_lengthening in component CE_velocity (per_um).
* CONSTANTS[29] is beta_P_lengthening in component CE_velocity (mN).
* CONSTANTS[30] is alpha_P_shortening in component CE_velocity (per_um).
* CONSTANTS[31] is beta_P_shortening in component CE_velocity (mN).
* CONSTANTS[32] is alpha_S_lengthening in component PE_velocity (per_um).
* CONSTANTS[33] is beta_S_lengthening in component PE_velocity (mN).
* CONSTANTS[34] is alpha_S_shortening in component PE_velocity (per_um).
* CONSTANTS[35] is beta_S_shortening in component PE_velocity (mN).
* ALGEBRAIC[13] is P_star in component average_crossbridge_force (dimensionless).
* ALGEBRAIC[12] is gamma in component average_crossbridge_force (dimensionless).
* CONSTANTS[46] is case_1 in component average_crossbridge_force (per_millisecond).
* ALGEBRAIC[15] is case_2 in component average_crossbridge_force (per_millisecond).
* CONSTANTS[47] is case_3 in component average_crossbridge_force (per_millisecond).
* ALGEBRAIC[16] is case_4 in component average_crossbridge_force (per_millisecond).
* ALGEBRAIC[26] is dA_dt in component calcium_handling (per_millisecond).
* ALGEBRAIC[18] is N_A in component calcium_handling (dimensionless).
* ALGEBRAIC[19] is pi_N_A in component calcium_handling (dimensionless).
* STATES[7] is B in component calcium_handling (dimensionless).
* ALGEBRAIC[20] is dB_dt in component calcium_handling (per_millisecond).
* STATES[8] is Ca_C in component calcium_handling (dimensionless).
* CONSTANTS[36] is A_tot in component calcium_handling (dimensionless).
* CONSTANTS[37] is B_tot in component calcium_handling (dimensionless).
* CONSTANTS[38] is b_on in component calcium_handling (per_millisecond).
* CONSTANTS[39] is b_off in component calcium_handling (per_millisecond).
* CONSTANTS[40] is a_c in component calcium_handling (per_millisecond2).
* CONSTANTS[41] is b_c in component calcium_handling (per_millisecond2).
* CONSTANTS[42] is r_Ca in component calcium_handling (per_millisecond).
* CONSTANTS[43] is q_Ca in component calcium_handling (dimensionless).
* CONSTANTS[44] is t_d in component calcium_handling (millisecond).
* RATES[1] is d/dt N in component crossbridge_kinetics (dimensionless).
* RATES[3] is d/dt l_1 in component length (um).
* RATES[4] is d/dt l_2 in component length (um).
* RATES[5] is d/dt l_3 in component length (um).
* RATES[0] is d/dt v in component CE_velocity (um_per_msec).
* RATES[2] is d/dt w in component PE_velocity (um_per_msec).
* RATES[6] is d/dt A in component calcium_handling (dimensionless).
* RATES[7] is d/dt B in component calcium_handling (dimensionless).
* RATES[8] is d/dt Ca_C in component calcium_handling (dimensionless).
* There are a total of 15 condition variables.
*/
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
CONSTANTS[0] = 1;
CONSTANTS[1] = 19;
CONSTANTS[2] = 2.9;
CONSTANTS[3] = 14.6;
CONSTANTS[4] = 0.01;
CONSTANTS[5] = 48;
CONSTANTS[6] = 0.1;
CONSTANTS[7] = 960;
CONSTANTS[8] = 0.6;
CONSTANTS[9] = 3;
CONSTANTS[10] = 0.705;
CONSTANTS[11] = 3;
CONSTANTS[12] = 0.9;
CONSTANTS[13] = 0.0056;
CONSTANTS[14] = 0.25;
CONSTANTS[15] = 0.5;
CONSTANTS[16] = 4;
CONSTANTS[17] = 1;
CONSTANTS[18] = 0.77;
CONSTANTS[19] = 0.017;
CONSTANTS[20] = 0.26;
CONSTANTS[21] = 0.03;
CONSTANTS[22] = 4;
CONSTANTS[23] = 4;
CONSTANTS[24] = 4;
CONSTANTS[25] = 2.9e-2;
CONSTANTS[26] = 0.2;
CONSTANTS[27] = 2.8;
STATES[0] = 0;
STATES[1] = 1;
STATES[2] = 0;
STATES[3] = 1;
STATES[4] = 1;
STATES[5] = 1;
STATES[6] = 0;
CONSTANTS[28] = 16;
CONSTANTS[29] = 15;
CONSTANTS[30] = 16;
CONSTANTS[31] = 15;
CONSTANTS[32] = 39;
CONSTANTS[33] = 80;
CONSTANTS[34] = 46;
CONSTANTS[35] = 60;
STATES[7] = 0;
STATES[8] = 0;
CONSTANTS[36] = 1;
CONSTANTS[37] = 0.4;
CONSTANTS[38] = 2.6;
CONSTANTS[39] = 0.182;
CONSTANTS[40] = 0.005;
CONSTANTS[41] = 0.03;
CONSTANTS[42] = 0.65;
CONSTANTS[43] = 50;
CONSTANTS[44] = 33;
CONSTANTS[45] = CONSTANTS[13]/10.0000;
CONSTANTS[46] = ( CONSTANTS[14]*(0.400000+ 0.400000*CONSTANTS[14]))/( CONSTANTS[13]*pow( (CONSTANTS[14]+1.00000)*0.400000, 2.00000));
CONSTANTS[47] = ( 0.400000*CONSTANTS[14]+1.00000)/( CONSTANTS[14]*CONSTANTS[13]);
STATES[9] = 0.1001;
STATES[10] = 0.1001;
RATES[1] = 0.1001;
RATES[3] = 0.1001;
RATES[4] = 0.1001;
RATES[5] = 0.1001;
RATES[0] = 0.1001;
RATES[2] = 0.1001;
RATES[6] = 0.1001;
RATES[7] = 0.1001;
RATES[8] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[1] - ALGEBRAIC[25];
resid[1] = RATES[3] - ALGEBRAIC[7];
resid[2] = RATES[4] - ALGEBRAIC[8];
resid[3] = RATES[5] - ALGEBRAIC[9];
resid[4] = STATES[9] - (CONSTANTS[0]==1.00000 ? ( CONSTANTS[7]*ALGEBRAIC[25]*ALGEBRAIC[17]*1.00000+ CONSTANTS[22]*ALGEBRAIC[10]*pow(STATES[0], 2.00000)+ CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])*STATES[2]*1.00000)/( CONSTANTS[7]*STATES[1]*STATES[10]*1.00000+ALGEBRAIC[10]) : ( CONSTANTS[7]*ALGEBRAIC[25]*ALGEBRAIC[17]*1.00000+ CONSTANTS[22]*ALGEBRAIC[10]*pow(STATES[0], 2.00000)+ ( CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])+ CONSTANTS[5]*CONSTANTS[6]*exp( CONSTANTS[5]*STATES[5]))*STATES[2]*1.00000)/( CONSTANTS[7]*STATES[1]*STATES[10]*1.00000+ALGEBRAIC[10]));
resid[5] = RATES[0] - STATES[9];
resid[6] = RATES[2] - (CONSTANTS[0]==1.00000 ? (( ALGEBRAIC[11]*(STATES[9] - CONSTANTS[23]*pow(STATES[2] - STATES[0], 2.00000)) - CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*(STATES[2] - STATES[0])*1.00000) - CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])*STATES[2]*1.00000)/ALGEBRAIC[11] : (( ALGEBRAIC[11]*(STATES[9] - CONSTANTS[23]*pow(STATES[2] - STATES[0], 2.00000)) - CONSTANTS[1]*CONSTANTS[2]*exp( CONSTANTS[1]*(STATES[4] - STATES[3]))*(STATES[2] - STATES[0])*1.00000) - ( CONSTANTS[3]*CONSTANTS[4]*exp( CONSTANTS[3]*STATES[4])+ CONSTANTS[5]*CONSTANTS[6]*exp( CONSTANTS[5]*STATES[5]))*STATES[2]*1.00000)/ALGEBRAIC[11]);
resid[7] = STATES[10] - (CONDVAR[8]<=0.00000 ? CONSTANTS[46]*STATES[9] : CONDVAR[9]<0.00000&&CONDVAR[10]<=0.00000 ? ALGEBRAIC[15]*STATES[9] : CONDVAR[11]<0.00000&&CONDVAR[12]<=0.00000 ? CONSTANTS[47]*STATES[9] : ALGEBRAIC[16]*STATES[9]);
resid[8] = RATES[6] - ALGEBRAIC[26];
resid[9] = RATES[7] - ALGEBRAIC[20];
resid[10] = RATES[8] - (CONDVAR[14]<0.00000 ? CONSTANTS[41]*VOI*(1.00000 - exp( - CONSTANTS[40]*pow(VOI, 2.00000)))*exp( - CONSTANTS[40]*pow(VOI, 2.00000)) : (- ALGEBRAIC[26] - ALGEBRAIC[20]) - CONSTANTS[42]*exp( - CONSTANTS[43]*STATES[8])*STATES[8]);
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[1] = CONSTANTS[2]*(exp( CONSTANTS[1]*(STATES[4] - STATES[3])) - 1.00000);
ALGEBRAIC[2] = CONSTANTS[4]*(exp( CONSTANTS[3]*STATES[4]) - 1.00000);
ALGEBRAIC[3] = CONSTANTS[6]*(exp( CONSTANTS[5]*STATES[5]) - 1.00000);
ALGEBRAIC[21] = CONSTANTS[7]*ALGEBRAIC[17]*STATES[1];
ALGEBRAIC[22] = ALGEBRAIC[3];
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[7] = STATES[0];
ALGEBRAIC[8] = STATES[2];
ALGEBRAIC[9] = (CONSTANTS[0]==1.00000 ? 0.00000 : - STATES[2]);
ALGEBRAIC[10] = (CONDVAR[1]<=0.00000 ? CONSTANTS[29]*exp( CONSTANTS[28]*STATES[3]) : CONSTANTS[31]*exp( CONSTANTS[30]*STATES[3]));
ALGEBRAIC[11] = (CONDVAR[2]<=0.00000 ? CONSTANTS[33]*exp( CONSTANTS[32]*(STATES[4] - STATES[3])) : CONSTANTS[35]*exp( CONSTANTS[34]*(STATES[4] - STATES[3])));
ALGEBRAIC[15] = ( CONSTANTS[14]*1.00000*(1.00000+ 0.400000*CONSTANTS[14]+( 1.20000*STATES[0])/CONSTANTS[13]+ 0.600000*pow(STATES[0]/CONSTANTS[13], 2.00000)))/( CONSTANTS[13]*pow( (CONSTANTS[14] - STATES[0]/CONSTANTS[13])*(1.00000+( 0.600000*STATES[0])/CONSTANTS[13]), 2.00000));
ALGEBRAIC[16] = (1.00000/CONSTANTS[13])*exp( - CONSTANTS[24]*pow(STATES[0]/CONSTANTS[13] - CONSTANTS[45]/CONSTANTS[13], CONSTANTS[17]))*(( 0.400000*CONSTANTS[14]+1.00000)/CONSTANTS[14]+ CONSTANTS[24]*CONSTANTS[16]*(1.00000+( ( 0.400000*CONSTANTS[14]+1.00000)*STATES[0])/( CONSTANTS[14]*CONSTANTS[13])))*pow(STATES[0]/CONSTANTS[13] - CONSTANTS[45]/CONSTANTS[13], CONSTANTS[17] - 1.00000);
ALGEBRAIC[12] = ( CONSTANTS[14]*CONSTANTS[15]*pow(CONSTANTS[45]/CONSTANTS[13], 2.00000))/( 3.00000*CONSTANTS[14]*CONSTANTS[15] - ( (CONSTANTS[14]+1.00000)*STATES[0])/CONSTANTS[13]);
ALGEBRAIC[13] = (CONDVAR[3]<=0.00000 ? ( CONSTANTS[14]*(1.00000+STATES[0]/CONSTANTS[13]))/(CONSTANTS[14] - STATES[0]/CONSTANTS[13]) : (1.00000+CONSTANTS[15]) - ( pow(CONSTANTS[15], 2.00000)*CONSTANTS[14])/( (( CONSTANTS[14]*CONSTANTS[15])/ALGEBRAIC[12])*pow(STATES[0]/CONSTANTS[13], 2.00000)+( (CONSTANTS[14]+1.00000)*STATES[0])/CONSTANTS[13]+ CONSTANTS[14]*CONSTANTS[15]));
ALGEBRAIC[14] = (CONDVAR[4]<=0.00000&&CONDVAR[5]<=0.00000 ? 1.00000+( 0.600000*STATES[0])/CONSTANTS[13] : CONDVAR[6]<0.00000&&CONDVAR[7]<=0.00000 ? ALGEBRAIC[13]/(( (( 0.400000*CONSTANTS[14]+1.00000)/CONSTANTS[14])*STATES[0])/CONSTANTS[13]+1.00000) : ( ALGEBRAIC[13]*exp( - CONSTANTS[24]*pow((STATES[0] - CONSTANTS[45])/CONSTANTS[13], CONSTANTS[17])))/(( (( 0.400000*CONSTANTS[14]+1.00000)/CONSTANTS[14])*STATES[0])/CONSTANTS[13]+1.00000));
ALGEBRAIC[17] = ALGEBRAIC[13]/ALGEBRAIC[14];
ALGEBRAIC[20] = CONSTANTS[38]*(CONSTANTS[37] - STATES[7])*STATES[8] - CONSTANTS[39]*STATES[7];
ALGEBRAIC[4] = pow(STATES[6], CONSTANTS[9])/(pow(STATES[6], CONSTANTS[9])+pow(CONSTANTS[8], CONSTANTS[9]));
ALGEBRAIC[5] = 0.600000*STATES[3]+0.500000;
ALGEBRAIC[6] = (STATES[3]+CONSTANTS[18])/(0.460000+CONSTANTS[18]);
ALGEBRAIC[0] = (CONDVAR[0]<=0.00000 ? CONSTANTS[19] - ( CONSTANTS[20]*STATES[0])/CONSTANTS[13] : CONSTANTS[21]);
ALGEBRAIC[23] = CONSTANTS[10]*CONSTANTS[11]*ALGEBRAIC[0]*CONSTANTS[12]*ALGEBRAIC[14];
ALGEBRAIC[24] = CONSTANTS[11]*ALGEBRAIC[0]*(1.00000 - CONSTANTS[10]*CONSTANTS[12]*ALGEBRAIC[14]);
ALGEBRAIC[25] = ALGEBRAIC[23]*ALGEBRAIC[4]*ALGEBRAIC[5]*ALGEBRAIC[6]*(1.00000 - STATES[1]) - ALGEBRAIC[24]*STATES[1];
ALGEBRAIC[18] = STATES[1]/( ALGEBRAIC[6]*STATES[6]);
ALGEBRAIC[19] = (CONDVAR[13]>=0.00000 ? 1.00000 : pow(0.0200000, ALGEBRAIC[18]));
ALGEBRAIC[26] = CONSTANTS[25]*(CONSTANTS[36] - STATES[6])*STATES[8] - CONSTANTS[26]*exp( - CONSTANTS[27]*STATES[6])*ALGEBRAIC[19]*STATES[6];
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[9] = 0.0;
SI[10] = 0.0;
SI[7] = 1.0;
SI[8] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
CONDVAR[0] = STATES[0] - 0.00000;
CONDVAR[1] = ALGEBRAIC[7] - 0.00000;
CONDVAR[2] = ALGEBRAIC[8] - ALGEBRAIC[7];
CONDVAR[3] = STATES[0] - 0.00000;
CONDVAR[4] = - CONSTANTS[13] - STATES[0];
CONDVAR[5] = STATES[0] - 0.00000;
CONDVAR[6] = 0.00000 - STATES[0];
CONDVAR[7] = STATES[0] - CONSTANTS[45];
CONDVAR[8] = STATES[0] - - CONSTANTS[13];
CONDVAR[9] = - CONSTANTS[13] - STATES[0];
CONDVAR[10] = STATES[0] - 0.00000;
CONDVAR[11] = 0.00000 - STATES[0];
CONDVAR[12] = STATES[0] - CONSTANTS[45];
CONDVAR[13] = ALGEBRAIC[18] - 1.00000;
CONDVAR[14] = VOI - CONSTANTS[44];
}