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Rong, Perelson, 2009
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Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
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Model Mathematics
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Component: environment
Component: uninfected
d
d
time
T
=
lambda
-
d_T
T
-
1
-
efficacy
k
V
T
Component: latently_infected
d
d
time
L_0
=
eta
1
-
efficacy
k
V
T
-
d_0
L_0
-
f
a
L_0
+
1
-
f
rho
L_a
Component: activated
d
d
time
L_a
=
f
a
L_0
+
p
L_a
-
1
-
f
a
+
rho
L_a
-
a_L
L_a
f
=
T_on
≦
time
time
<
T_off
Component: productively_infected
d
d
time
T_star
=
1
-
eta
1
-
efficacy
k
V
T
-
1
delta
T_star
T_star
+
a_L
L_a
Component: viral_load
d
d
time
V
=
p_v
T_star
-
c
V
Component: drug_efficacy
Source
Derived from workspace
Rong, Perelson 2009
at changeset
bfe9c2d63670
.
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Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy