- Author:
- Matthias K?nig <matthias.koenig@charite.de>
- Date:
- 2013-03-26 09:19:22+01:00
- Desc:
- CellML files changed from CellML v1.0 -> v1.1 to support import of the components.
Additional header added to CellML files for metabolic component library.
- Permanent Source URI:
- http://models.cellml.org/w/matthiaskoenig/MetabolicComponentLibrary/rawfile/bd03a62054a456c8351815de9d5770a465473898/MetabolicComponentLibrary.htm
Library of metabolic components in CeLLML
Matthias Koenig [1] &
Randall Britten [2]
[1] Charite Berlin, matthias.koenig@charite.de
[2] Auckland Bioengineering Institute
Implementation of standardized reaction kinetics in CellML for reuse in metabolic models.
The library covers the metabolic function definitions for processes from COPASI 4.8 (Bulid 35).
Naming Conventions
Substrate is named S (S1, S2, ... in case of multiple substrates)
Products is named P (P1, P2, ... in case of multiple productes)
Inhibitor is named I (I1, I2, ...)
Activator is named A (A1, A2, ...)
Modifier is named M (M1, M2, ...)
Km values are subscripted with the respective substrates or products (P -> Km_P, S -> Km_S, P1 -> Km_P1, ...).
Analog convention for inhibition constants Ki and activation constants Ka.
Units
Time: second
Volume Unit: liter
Quantity Unit: mmol
Components
PingPongBiBi
AllostericInhibitionEmpirical
AllostericInhibitionMWC
BiIrrev
CatalyticActivationIrrev
CatalyticActivationRev
CompetitiveInhibitionIrrev
CompetitiveInhibitionRev
ConstantFlux
HenriMichaelisMentenIrrev
HillCooperativity
HyperbolicModifierIrrev
HyperbolicModifierRev
IsoUniUni
MassActionBiBiRev
MassActionBiIrrev
MassActionBiUniRev
MassActionUniBiRev
MassActionUniIrrev
MassActionUniUniRev
MixedActivationIrrev
MixedActivationRev
MixedInhibitionIrrev
MixedInhibitionRev
NoncompetitiveInhibitionIrrev
NoncompetitiveInhibitionRev
OrderedBiBi
OrderedBiUni
OrderedUniBi
PingPongBiBi
ReversibleHill
ReversibleHill1Modifier
ReversibleHill2Modifier
ReversibleMichaelisMenten
SpecificActivationIrrev
SpecificActivationRev
SubstrateActivationIrrev
SubstrateInhibitionIrrev
SubstrateInhibitionRev
UncompetitiveInhibitionIrrev
UncompetitiveInhibitionRev
UniUni