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Karagiannis, Popel, 2006
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Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model
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Model Mathematics
Component based math viewer is available
Component: environment
Component: Model
d
d
t
M2
=
-
kM2T2_on
M2
T2
+
kM2T2_off
M2T2
-
kM2C1_on
M2
C1
+
kM2C1_off
+
kM2C1_cat
M2C1
+
kM2_act
MT1T2M2proMT1
d
d
t
MT1
=
qMT1
-
kMT1_shedeff
MT1
MT1
-
kMT1T2_on
MT1
T2
+
kMT1T2_off
MT1T2
-
kMT1C1_on
MT1
C1
+
kMT1C1_off
+
kMT1C1_cat
MT1C1
-
kMT1T2M2proMT1_on
MT1
MT1T2M2pro
+
kMT1T2M2proMT1_off
MT1T2M2proMT1
+
kM2_act
MT1T2M2proMT1
d
d
t
MT1_t
=
kMT1_shedeff
MT1
MT1
d
d
t
MT1C1
=
kMT1C1_on
MT1
C1
-
kMT1C1_off
+
kMT1C1_cat
MT1C1
d
d
t
MT1T2
=
kMT1T2_on
MT1
T2
-
kMT1T2_off
MT1T2
-
kMT1T2M2pro_on
MT1T2
M2_p
+
kMT1T2M2pro_off
MT1T2M2pro
d
d
t
MT1T2M2pro
=
kMT1T2M2pro_on
MT1T2
M2_p
-
kMT1T2M2pro_off
MT1T2M2pro
-
kMT1T2M2proMT1_on
MT1
MT1T2M2pro
+
kMT1T2M2proMT1_off
MT1T2M2proMT1
d
d
t
MT1T2M2proMT1
=
kMT1T2M2proMT1_on
MT1
MT1T2M2pro
-
kMT1T2M2proMT1_off
MT1T2M2proMT1
-
kM2_act
MT1T2M2proMT1
d
d
t
C1
=
-
kMT1C1_on
MT1
C1
+
kMT1C1_off
MT1C1
-
kM2C1_on
M2
C1
+
kM2C1_off
M2C1
d
d
t
C1_D
=
kM2C1_cat
M2C1
+
kMT1C1_cat
MT1C1
d
d
t
MT1_cat
=
kMT1_shedeff
MT1
MT1
d
d
t
T2
=
-
kM2T2_on
M2
T2
+
kM2T2_off
M2T2
+
qT2
-
kMT1T2_on
MT1
T2
+
kMT1T2_off
MT1T2
d
d
t
M2_p
=
qpro
-
kMT1T2M2pro_on
MT1T2
M2_p
+
kMT1T2M2pro_off
MT1T2M2pro
d
d
t
M2T2
=
kM2T2_on
M2
T2
-
kM2T2_off
M2T2
-
kM2T2_iso
M2T2
+
kM2T2_negativeiso
M2T2_star
d
d
t
M2T2_star
=
kM2T2_iso
M2T2
-
kM2T2_negativeiso
M2T2_star
d
d
t
M2C1
=
kM2C1_on
M2
C1
-
kM2C1_off
+
kM2C1_cat
M2C1
d
d
t
MT1T2_star
=
kM2_act
MT1T2M2proMT1
Source
Derived from workspace
Karagiannis, Popel, 2006
at changeset
fd1abfb0f5e8
.
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Creative Commons Attribution 3.0 Unported License
.
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Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model