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Tomida, Hirose, Takizawa, Shibasaki, Iino, 2003
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NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation
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Model Mathematics
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Component: model
stim_on
=
1
if
time
≥
time_before_stim
∧
time
-
time_before_stim
mod
stim_wavelength
≦
stim_duration
0
otherwise
k1
=
k1_stim
if
stim_on
=
1
k1_unstim
otherwise
Jdephosphorylation
=
k1
NFATP_cyt
-
k2
NFAT_cyt
Jtranslocate
=
k3
NFAT_cyt
Jexport
=
k4
NFAT_nuc
d
d
time
NFATP_cyt
=
Jexport
-
Jdephosphorylation
d
d
time
NFAT_cyt
=
Jdephosphorylation
-
Jtranslocate
d
d
time
NFAT_nuc
=
Jtranslocate
-
Jexport
NFAT_tot
=
NFATP_cyt
+
NFAT_cyt
+
NFAT_nuc
percentage_NFAT_cyt
=
NFAT_cyt
100
NFAT_tot
percentage_NFATP_cyt
=
NFATP_cyt
100
NFAT_tot
percentage_NFAT_nuc
=
NFAT_nuc
100
NFAT_tot
Source
Derived from workspace
Tomida, Hirose, Takizawa, Shibasaki, Iino, 2003
at changeset
62dff918ae0a
.
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NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation