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C C There are a total of 13 entries in the algebraic variable array. C There are a total of 5 entries in each of the rate and state variable arrays. C There are a total of 41 entries in the constant variable array. C C C CONSTS(1) is t_ss in component Vstim_para (second). C CONSTS(2) is V_actHolding in component Vstim_para (mV). C CONSTS(3) is t_act in component Vstim_para (second). C CONSTS(4) is V_actTest in component Vstim_para (mV). C CONSTS(5) is t_intp in component Vstim_para (second). C CONSTS(6) is np in component Vstim_para (dimensionless). C CONSTS(7) is Nai in component control_para (mM). C CONSTS(8) is Cai_init in component control_para (mM). C CONSTS(9) is inhPump in component control_para (dimensionless). C VOI is time in component time_s (second). C ALGBRC(5) is V in component mPulse_protocol_s (mV). C STATES(1) is Cai in component Cai (mM). C ALGBRC(13) is J_VOCC in component J_VOCC (mM_per_s). C ALGBRC(8) is J_CaPump in component J_CaPump (mM_per_s). C ALGBRC(11) is J_NaCa in component J_NaCa (mM_per_s). C ALGBRC(1) is stress in component CB4HM (dimensionless). C ALGBRC(2) is phosphorylation in component CB4HM (dimensionless). C CONSTS(10) is R in component constants (J_per_K_mol). C CONSTS(11) is F in component constants (C_per_mmol). C CONSTS(12) is T in component model_para (kelvin). C CONSTS(13) is Nao in component model_para (mM). C CONSTS(14) is Cao in component model_para (mM). C CONSTS(15) is V_cell in component model_para (fm3). C CONSTS(16) is V_Cahalf in component model_para (mV). C CONSTS(17) is K_Cahalf in component model_para (mV). C CONSTS(18) is g_mCa in component model_para (nS). C CONSTS(19) is V_pmax in component model_para (mM_per_s). C CONSTS(20) is n in component model_para (dimensionless). C CONSTS(21) is K_ph in component model_para (mM). C CONSTS(22) is K_NaCa in component model_para (mM). C CONSTS(23) is G_NaCa in component model_para (mM_per_s_mV). C CONSTS(24) is n_M in component model_para (dimensionless). C CONSTS(25) is Ca_halfMLCK in component model_para (mM). C CONSTS(26) is M_init in component initials (dimensionless). C CONSTS(27) is Mp_init in component initials (dimensionless). C CONSTS(28) is AM_init in component initials (dimensionless). C CONSTS(29) is AMp_init in component initials (dimensionless). C CONSTS(30) is K_7 in component model_para (per_s). C CONSTS(31) is K_2 in component model_para (per_s). C CONSTS(32) is K_3 in component model_para (per_s). C CONSTS(33) is K_4 in component model_para (per_s). C CONSTS(34) is K_5 in component model_para (per_s). C ALGBRC(7) is rho_vCa in component J_VOCC (dimensionless). C CONSTS(41) is stimPeriod in component mPulse_protocol_s (second). C ALGBRC(3) is t in component mPulse_protocol_s (second). C CONSTS(35) is Nai in component model_para (mM). C CONSTS(36) is inhPump in component model_para (dimensionless). C CONSTS(37) is Cai_init in component initials (mM). C CONSTS(38) is z_Ca in component E_Ca (dimensionless). C ALGBRC(9) is E in component Nernst_potential (mV). C CONSTS(39) is z_Na in component E_Na (dimensionless). C CONSTS(40) is E in component Nernst_potential (mV). C ALGBRC(12) is I in component Ionic_currents (pA). C ALGBRC(10) is V_mNaCa in component J_NaCa (mV). C ALGBRC(6) is K_1 in component K_1 (per_s). C ALGBRC(4) is norm in component CB4HM (dimensionless). C STATES(2) is M in component CB4HM (dimensionless). C STATES(3) is Mp in component CB4HM (dimensionless). C STATES(4) is AM in component CB4HM (dimensionless). C STATES(5) is AMp in component CB4HM (dimensionless). C RATES(1) is d/dt Cai in component Cai (mM). C RATES(2) is d/dt M in component CB4HM (dimensionless). C RATES(3) is d/dt Mp in component CB4HM (dimensionless). C RATES(4) is d/dt AM in component CB4HM (dimensionless). C RATES(5) is d/dt AMp in component CB4HM (dimensionless). C SUBROUTINE initConsts(CONSTS, RATES, STATES) REAL CONSTS(*), RATES(*), STATES(*) CONSTS(1) = 0 CONSTS(2) = -80 CONSTS(3) = 0.1 CONSTS(4) = 0 CONSTS(5) = 0.33 CONSTS(6) = 10 CONSTS(7) = 16.55 CONSTS(8) = 0.1e-3 CONSTS(9) = 1 CONSTS(10) = 8.314 CONSTS(11) = 96.48534 CONSTS(12) = 310 CONSTS(13) = 140 CONSTS(14) = 2 CONSTS(15) = 21 CONSTS(16) = -27 CONSTS(17) = 11 CONSTS(18) = 0.046842 CONSTS(19) = 5.1449e-4 CONSTS(20) = 1.9015 CONSTS(21) = 0.6e-3 CONSTS(22) = 7e-3 CONSTS(23) = 5.7297e-5 CONSTS(24) = 8.7613 CONSTS(25) = 256.98e-6 CONSTS(26) = 1 CONSTS(27) = 0 CONSTS(28) = 0 CONSTS(29) = 0 CONSTS(30) = 0.0378 CONSTS(31) = 1.2387 CONSTS(32) = 0.1419 CONSTS(33) = 0.035475 CONSTS(34) = 1.2387 CONSTS(35) = 2.9836 CONSTS(36) = 1 CONSTS(37) = 0.1e-6 CONSTS(38) = 2 CONSTS(39) = 1 CONSTS(40) = (( CONSTS(10)*CONSTS(12))/( CONSTS(39)*CONSTS(11)))*log(CONSTS(13)/CONSTS(7)) CONSTS(41) = CONSTS(3)+CONSTS(5) STATES(1) = CONSTS(8) STATES(2) = CONSTS(26) STATES(3) = CONSTS(27) STATES(4) = CONSTS(28) STATES(5) = CONSTS(29) RETURN END SUBROUTINE computeRates(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(6) = (STATES(1) ** CONSTS(24)/(CONSTS(25) ** CONSTS(24)+STATES(1) ** CONSTS(24)))*1.00000 ALGBRC(4) = STATES(2)+STATES(3)+STATES(4)+STATES(5) RATES(2) = ( - ALGBRC(6)*STATES(2))/ALGBRC(4)+( CONSTS(31)*STATES(3))/ALGBRC(4)+( CONSTS(30)*STATES(4))/ALGBRC(4) RATES(3) = (( CONSTS(33)*STATES(5))/ALGBRC(4)+( ALGBRC(6)*STATES(2))/ALGBRC(4)) - ( (CONSTS(31)+CONSTS(32))*STATES(3))/ALGBRC(4) RATES(4) = ( CONSTS(34)*STATES(5))/ALGBRC(4) - ( (ALGBRC(6)+CONSTS(30))*STATES(4))/ALGBRC(4) RATES(5) = (( CONSTS(32)*STATES(3))/ALGBRC(4)+( ALGBRC(6)*STATES(4))/ALGBRC(4)) - ( (CONSTS(33)+CONSTS(34))*STATES(5))/ALGBRC(4) ALGBRC(3) = (VOI - CONSTS(1)) - CONSTS(41)*INT((VOI - CONSTS(1))/CONSTS(41)) ALGBRC(5) = TERNRY(VOI.LE.CONSTS(1), CONSTS(2), TERNRY(VOI.GT.CONSTS(1).AND.ALGBRC(3).LE.CONSTS(3).AND.VOI.LE.CONSTS(1)+ CONSTS(41)*CONSTS(6), CONSTS(4), CONSTS(2)) ALGBRC(7) = 1.00000/(1.00000+EXP((CONSTS(16) - ALGBRC(5))/CONSTS(17))) ALGBRC(9) = (( CONSTS(10)*CONSTS(12))/( CONSTS(38)*CONSTS(11)))*log(CONSTS(14)/STATES(1)) ALGBRC(12) = CONSTS(18)*ALGBRC(7)*(ALGBRC(5) - ALGBRC(9)) ALGBRC(13) = - ALGBRC(12)/( 2.00000*CONSTS(15)*CONSTS(11)) ALGBRC(8) = ( - CONSTS(19)*STATES(1) ** CONSTS(20))/(CONSTS(21) ** CONSTS(20)+STATES(1) ** CONSTS(20)) ALGBRC(10) = 3.00000*CONSTS(40) - 2.00000*ALGBRC(9) ALGBRC(11) = (( CONSTS(23)*STATES(1))/(STATES(1)+CONSTS(22)))*(ALGBRC(5) - ALGBRC(10)) RATES(1) = ALGBRC(13)+ CONSTS(9)*ALGBRC(8)+ALGBRC(11) RETURN END SUBROUTINE computeVariables(VOI, CONSTS, RATES, STATES, ALGBRC) REAL VOI, CONSTS(*), RATES(*), STATES(*), ALGBRC(*) ALGBRC(6) = (STATES(1) ** CONSTS(24)/(CONSTS(25) ** CONSTS(24)+STATES(1) ** CONSTS(24)))*1.00000 ALGBRC(4) = STATES(2)+STATES(3)+STATES(4)+STATES(5) ALGBRC(3) = (VOI - CONSTS(1)) - CONSTS(41)*INT((VOI - CONSTS(1))/CONSTS(41)) ALGBRC(5) = TERNRY(VOI.LE.CONSTS(1), CONSTS(2), TERNRY(VOI.GT.CONSTS(1).AND.ALGBRC(3).LE.CONSTS(3).AND.VOI.LE.CONSTS(1)+ CONSTS(41)*CONSTS(6), CONSTS(4), CONSTS(2)) ALGBRC(7) = 1.00000/(1.00000+EXP((CONSTS(16) - ALGBRC(5))/CONSTS(17))) ALGBRC(9) = (( CONSTS(10)*CONSTS(12))/( CONSTS(38)*CONSTS(11)))*log(CONSTS(14)/STATES(1)) ALGBRC(12) = CONSTS(18)*ALGBRC(7)*(ALGBRC(5) - ALGBRC(9)) ALGBRC(13) = - ALGBRC(12)/( 2.00000*CONSTS(15)*CONSTS(11)) ALGBRC(8) = ( - CONSTS(19)*STATES(1) ** CONSTS(20))/(CONSTS(21) ** CONSTS(20)+STATES(1) ** CONSTS(20)) ALGBRC(10) = 3.00000*CONSTS(40) - 2.00000*ALGBRC(9) ALGBRC(11) = (( CONSTS(23)*STATES(1))/(STATES(1)+CONSTS(22)))*(ALGBRC(5) - ALGBRC(10)) ALGBRC(1) = STATES(5)+STATES(4) ALGBRC(2) = STATES(5)+STATES(3) RETURN END REAL FUNCTION TERNRY(TEST, VALA, VALB) LOGICAL TEST REAL VALA, VALB IF (TEST) THEN TERNRY = VALA ELSE TERNRY = VALB ENDIF RETURN END