Full List

Below is a listing of model exposures (100 per page | full list)

A Quantitative Model of Human Jejunal Smooth Muscle Cell Electrophysiology
An analysis of deformation-dependent electromechanical coupling in the mouse heart
Davies ISAP 2012
Ionic mechanisms for electrical heterogeneity between rabbit Purkinje fiber and ventricular cells
Simulations of the effects of inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase activities on Ca2+ oscillations
[Ca2+]i oscillations in sympathetic neurons: an experimental test of a theoretical model
A 0D model of the Heart
A model for pacemaking in substantia nigra neurons (A simple model based on a spherical geometry)
A model for pacemaking in substantia nigra neurons (A simple model based on a spherical geometry)
A Primer on Modular Mass Action Modelling with CellML
A single compartment model of pacemaking in dissasociated Substantia nigra neurons with hyperbolic tetrahedral geometry
A single compartment model of pacemaking in dissasociated Substantia nigra neurons with hyperbolic tetrahedral geometry
A Tutorial on Creating a Systems Model from SVPs
Activation of the Liver Glycogen Phosphorylase by Ca2+ Oscillations: a Theoretical Study
Adrian, Chandler, Hodgkin, 1970
Voltage clamp experiments in striated muscle fibres
Aguda, 1999
A quantitative analysis of the kinetics of the G2 DNA damage checkpoint system
Aguda, B, 1999
Aguda, Tang, 1999
The kinetic origins of the restriction point in the mammalian cell cycle
Albrecht, Colegrove, Friel, 2002
Differential Regulation of ER Ca2+ Uptake and Release Rates Accounts for Multiple Modes of Ca2+-induced Ca2+ Release
Albrecht, Colegrove, Hongpaisan, Pivovarova, Andrews, Friel, 2001
Multiple Modes of Calcium-induced Calcium Release in Sympathetic Neurons I: Attenuation of Endoplasmic Reticulum Ca2+ Accumulation at Low [Ca2+]i during Weak Depolarisation
Alexander, Wahl, 2010
Self-tolerance and Autoimmunity in a Regulatory T Cell Model
Alexander, Wahl, 2010
Self-tolerance and Autoimmunity in a Regulatory T Cell Model
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis
An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation.
Andre playing with nested tasks in SED-ML
Andre's Hodgkin & Huxley with CellML
Andre's Hodgkin & Huxley with CellML
Aon, Cortassa, 2002
Coherent and robust modulation of a metabolic network by cytoskeletal organization and dynamics
Arresting the mitotic oscillator and the control of cell proliferation: insights from a cascade model for cdc2 kinase activation
Arresting the mitotic oscillator and the control of cell proliferation: insights from a cascade model for cdc2 kinase activation
Arresting the mitotic oscillator and the control of cell proliferation: insights from a cascade model for cdc2 kinase activation
Aslanidi 2009
Aslanidi, Boyett, Dobrzynski, Li, Zhang, 2009
Mechanisms of transition from normal to reentrant electrical activity in a model of rabbit atrial tissue: interaction of tissue heterogeneity and anisotropy
Aslanidi, Stewart, Boyett, Zhang, 2009
Optimal velocity and safety of discontinuous conduction through the heterogeneous Purkinje-ventricular junction
Asthagiri, Lauffenburger, 2001
A Compuational Study of Feedback Effects on Signal Dynamics in a Mitogen-Activated Protein Kinase (MAPK) Pathway Model
Bagci 2008
Bagci, Vodovotz, Billiar, Ermentrout, Bahar, 2006
Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores
Bagci, Vodovotz, Billiar, Ermentrout, Bahar, 2008
Computational insights on the competing effects of nitric oxide in regulating apoptosis
Bakker, Mensonides, Teusink, van Hoek, Michels, Westerhoff, 2000
Compartmentation protects trypanosomes from the dangerous design of glycolysis
Bakker, Michels, Opperdoes, Westerhoff, 1997
Glycolysis in Bloodstream Form Trypanosoma brucei Can Be Understood in Terms of the Kinetics of the Glycolytic Enzymes
Barberis, Klipp, Vanoni, Alberghina, 2007
Barberis, Klipp, Vanoni, Alberghina, 2007
Cell Size at S Phase Initiation: An Emergent Property of the G1/S Network
Basket Catheter Emulator
Baylor, Hollingworth, Chandler, 2002
Comparison of Simulated and Measured Calcium Sparks in Intact Skeletal Muscle Fibers of the Frog
Beard, 2005
A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation
Ben-Tal, 2006
Simplified models for gas exchange in the human lungs
Ben-Tal, 2006
Simplified models for gas exchange in the human lungs
Benson, Aslanidi, Zhang, Holden, 2008
The canine virtual ventricular wall: a platform for dissecting pharmacological effects on propagation and arrhythmogenesis
Benson, Aslanidi, Zhang, Holden, 2008
The canine virtual ventricular wall: a platform for dissecting pharmacological effects on propagation and arrhythmogenesis
Bernus, Wilders, Zemlin, Verschelde, Panfilov, 2002
A computationally efficient electrophysiological model of human ventricular cells
Bertram, Arnot, Zamponi, 2002
Role for G protein G-beta-gamma isoform specificity in synaptic signal processing: a computational study
Bertram, Pedersen, Luciani, Sherman, 2006
A simplified model for mitochondrial ATP production
Bertram, Previte, Sherman, Kinard, Satin, 2000
The Phantom Burster Model for Pancreatic Beta Cells
Bertram, Rhoads, Cimbora, 2008
A phantom bursting mechanism for episodic bursting
Bertram, Satin, Pedersen, Luciani, Sherman, 2007
Intra- and inter-islet synchronization of metabolically driven insulin secretion
Bertram, Satin, Zhang, Smolen, Sherman, 2004
Calcium and Glycolysis Mediate Multiple Bursting Modes in Pancreatic Islets
Bertram, Sherman, 2004
A Calcium-based Phantom Bursting Model for Pancreatic Islets
Bertram, Smolen, Sherman, Mears, Atwater, Martin, Soria, 1995
A role for calcium release-activated current (CRAC) in cholinergic modulation of electrical activity in pancreatic beta-cells
Bhalla, Iyengar, 1999
Emergent Properties of Networks of Biological Signaling Pathways
Bifurcation analysis of the regulatory modules of the mammalian G1/S transition
Bindschadler, Sneyd, 2001
A Bifurcation Analysis of Two Coupled Calcium Oscillators
Bingzheng, Zhenye, Liansong, 1990
A mathematical model of the regulation system of the secretion of glucocorticoids
Bondarenko, Szigeti, Bett, Kim, Rasmusson, 2004
Computer model of action potential of mouse ventricular myocytes
Bonhoeffer, Rembiszewski, Ortiz, Nixon, 2000
Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection
Borghans, Dupont, Goldbeter, 1997
Complex intracellular calcium oscillations. A theoretical exploration of possible mechanisms
Bornheimer, Maurya, Farquhar, Subramaniam, 2004
Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction
Boyett, Zhang, Garny, Holden, 2001
Control of the pacemaker activity of the sinoatrial node by intracellular Ca2+. Experiments and modelling
Brightman, Fell, 2000
Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells.
Brown, Choe, Shanahan, Czeisler, 1997
A mathematical model of diurnal variations in human plasma melatonin levels
Bueno, 2007
Mathematical modeling and spectral simulation of genetic diseases in the human heart
Bugbuster Systems Model
Bugenhagen 2010
Bugenhagen 2010
Model of the overall baroreflex heart rate control system.
Butera, Rinzel, Smith, 1999
Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. II. Populations of Coupled Pacemaker Neurons
Butera, Rinzel, Smith, 1999
Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. I. Bursting Pacemaker Neurons
Butera, Rinzel, Smith, 1999
Models of Respiratory Rhythm Generation in the Pre-Botzinger Complex. II. Populations of Coupled Pacemaker Neurons
Calzone, Thieffry, Tyson, Novak, 2007
Dynamical modeling of syncytial mitotic cycles in Drosophila embryos
Campbell, Chandra, 2006
Functions of Stretch Activation in Heart Muscle
Carro, Rodriguez, Laguna, Pueyo (2011)
In this study, several modifications were introduced to a recently proposed human ventricular action potential (AP) model so as to render it suitable for the study of ventricular arrhythmias. These modifications were driven by new sets of experimental data available from the literature and the analysis of several well-established cellular arrhythmic risk biomarkers, namely AP duration at 90 per cent repolarization (APD90), AP triangulation, calcium dynamics, restitution properties, APD90 adaptation to abrupt heart rate changes, and rate dependence of intracellular sodium and calcium concentrations. The proposed methodology represents a novel framework for the development of cardiac cell models. Five stimulation protocols were applied to the original model and the ventricular AP model developed here to compute the described arrhythmic risk biomarkers. In addition, those models were tested in a one-dimensional fibre in which hyperkalaemia was simulated by increasing the extracellular potassium concentration, [K+]o. The effective refractory period (ERP), conduction velocity (CV) and the occurrence of APD alternans were investigated. Results show that modifications improved model behaviour as verified by: (i) AP triangulation well within experimental limits (the difference between APD at 50 and 90 per cent repolarization being 78.1 ms); (ii) APD90 rate adaptation dynamics characterized by fast and slow time constants within physiological ranges (10.1 and 105.9 ms); and (iii) maximum S1S2 restitution slope in accordance with experimental data (SS1S2=1.0). In simulated tissues under hyperkalaemic conditions, APD90 progressively shortened with the degree of hyperkalaemia, whereas ERP increased once a threshold in [K+]o was reached ([K+]o= 6 mM). CV decreased with [K+]o, and conduction was blocked for [K+]o>10.4 mM. APD90 alternans were observed for [K+]o>9.8 mM. Those results adequately reproduce experimental observations. This study demonstrated the value of basing the development of AP models on the computation of arrhythmic risk biomarkers, as opposed to joining together independently derived ion channel descriptions to produce a whole-cell AP model, with the new framework providing a better picture of the model performance under a variety of stimulation conditions. On top of replicating experimental data at single-cell level, the model developed here was able to predict the occurrence of APD90 alternans and areas of conduction block associated with high [K+]o in tissue, which is of relevance for the investigation of the arrhythmogenic substrate in ischaemic hearts.
Cartwright, Husain, 1986
A model for the control of testosterone secretion
Cell Viability Models for Tissue Exposed to Ablative Temperatures
Cell viability models for tissue exposed to ablative temperatures.
Chang, Fujita, 1999
Chang, Fujita, 1999
A kinetic model of the thiazide-sensitive Na-Cl cotransporter
Chang, Fujita, 1999
A numerical model of the renal distal tubule
Chang, Fujita, 2001
A numerical model of acid-base transport in rat distal tubule
Chassagnole, Rais, Quentin, Fell, Mazat, 2001
An integrated study of Threonine-pathway enzyme kinetics in Escherichia coli
Chay, 1997
Effects of extracellular calcium on electrical bursting and intracellular and luminal calcium oscillations in insulin secreting pancreatic beta-cells
Chay, Lee, Fan, 1995
Appearance of Phase-locked Wenchbach-like Rhythms, Devil's Staircase and Universality in Intracellular Calcium Spikes in Non-excitable Cell Models
Chen, Calzone, Csikasz-Nagy, Cross, Novak, Tyson, 2004
Integrative Analysis of Cell Cycle Control in Budding Yeast
Chen, Csikasz-Nagy, Gyorffy, Val, Novak, Tyson, 2000
Kinetic Analysis of a Molecular Model of the Budding Yeast Cell Cycle
Chen, Popel, 2006
Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells
Chen, Popel, 2007
Vascular and perivascular nitric oxide release and transport: biochemical pathways of neuronal nitric oxide synthase (NOS1) and endothelial nitric oxide synthase (NOS3)
Cheng, Brown, Loeb, 2000
Virtual muscle: a computational approach to understanding the effects of muscle properties on motor control
Ciliberto, Novak, Tyson, 2003
Mathematical Model of the Morphogenesis Checkpoint in Budding Yeast
Ciliberto, Petrus, Tyson, Sible, 2003
A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus
Ciliberto, Tyson, 2000
Mathematical Model for Early Development of the Sea Urchin Embryo
Cl-/HCO3- Exchanger (AE1) Model
Clancy, Rudy, 2001
Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death
Clancy, Rudy, 2002
Na Channel Mutation That Causes Both Brugada Syndrome and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism
Cloutier, Bolger, Lowry, Wellstead, 2009
An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements
Cloutier, Wellstead, 2009
The control systems structures of energy metabolism
Colegrove, Albrecht, Friel, 2000
Quantitive Analysis of Mitochondrial Ca2+ Uptake and Release Pathways in Sympathetic Neurons Reconstruction of the Recovery after Depolarisation-evoked [Ca2+] Elevations
Collier et al (1996) Delta-Notch model
Computational Mechanics of the Heart
Computational models of ventricular- and atrial-like human induced pluripotent stem cell derived cardiomyocytes
Computational models of ventricular- and atrial-like human induced pluripotent stem cell derived cardiomyocytes
Conradie, Bruggeman, Ciliberto, Csikasz-Nagy, Novak, Westerhoff, Snoep,
Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex
Cooling, Hunter, Crampin, 2008
Cooling, Hunter, Crampin, 2009. Dual Calcium Protocol
Cooling, Hunter, Crampin, 2009. Shen Calcium Protocol
Cooling, Hunter, Crampin, 2009. Tomida Calcium Protocol
Corrias, Buist, 2007
Corrias, Buist, 2007
Corrias, Buist, 2008
Quantitative cellular description of gastric slow wave activity
Cortassa et al. (2006) ECME model
Cortassa, Aon, Marban, Winslow, O'Rourke, 2003
An Integrated Model of Cardiac Mitrochondrial Energy Metabolism and Calcium Dynamics
Cortassa, Aon, Winslow, O'Rourke, 2004
A mitochondrial oscillator dependent on reactive oxygen species
Costa, Holmes, McCulloch, 2001
Modelling Cardiac Mechanical Properties In Three Dimensions
Courtemanche, Ramirez, Nattel, 1998
Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model
Covering a broad dynamic range: information processing at the erythropoietin receptor
Cronwright, Rohwer, Prior, 2002
Metabolic Control Analysis of Glycerol Synthesis in Saccharomyces cerevisiae
Csikasz-Nagy, Battogtokh, Chen, Novak, Tyson, 2006
Analysis of a generic model of eukaryotic cell-cycle regulation: budding yeast taken from the original model code
Cui, Kaandorp, 2006
Mathematical modeling of calcium homeostasis in yeast cells
Cui, Kaandorp, 2008
Simulating Complex Calcium-Calcineurin Signaling Network
Cui, Kaandorp, Lloyd, 2008
Simulating in vitro transcriptional response of zinc homeostasis system in Escherichia coli
Curien, Ravanel, Dumas, 2003
A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana
Dash, Bassingthwaighte, 2004
Blood HbO2 and HbCO2 dissociation curves at varied O2, CO2, pH, 2,3-DPG and temperature levels
David Cumin PhD Model
Dawson, Lea, Irvine, 2003
Kinetic model of the inositol trisphosphate receptor that shows both steady-state and quantal patterns of Ca2+ release from intracellular stores
De Paor, Timmons, 1986
A feedback oscillator model for circulatory autoregulation
De Vries, Sherman, 2000
Channel Sharing in Pancreatic Beta-Cells Revisited: Enhancement of Emergent Bursting by Noise
De Vries, Sherman, 2001
From Spikers to Bursters Via Coupling: Help from Heterogeneity
De Young, Keizer, 1992
A single-pool inositol 1,4,5-triphosphate-receptor-based model for agonist-stimulated oscillations in Ca 2+ concentration
Decker, Heijman, Silva, Hund, Rudy, 2009
Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium
Demir, Clark, Giles, 1999
Parasympathetic modulation of sinoatrial node pacemaker activity in rabbit heart: a unifying model
Demir, Clark, Giles, Murphey, 1994
A Mathematical Model of a Rabbit Sinoatrial Node Cell
Demiray, 1981
Large deformation analysis of some soft biological tissues
Dempsher, Gann, Phair, 1984
A mechanistic model of ACTH-stimulated cortisol secretion
Dependence of the period on the rate of protein degradation in minimal models for circadian oscillations
DiFrancesco, Noble, 1985
A Model of Cardiac Electrical Activity Incorporating Ionic Pumps and Concentration Changes
Dijkstra, Neal, Beever, France, 1992
Simulation of nutrient digestion, absorption and outflow in the rumen: model description
Dixit, Perelson, 2004
Complex patterns of viral load decay under antiretroviral therapy: influence of pharmacokinetics and intracellular delay
Dokos, Celler, Lovell, 1996
Ion currents underlying sinoatrial node pacemaker activity: a new single cell mathematical model
Dougherty, Wright, Yew, 2005
Computational model of the cAMP-mediated sensory response and calcium-dependent adaptation in vertebrate olfactory receptor neurons
Drouhard, Roberge, 1987
Revised formulation of the Hodgkin-Huxley representation of the sodium current in cardiac cells
Dumaine, Towbin, Brugada, Vatta, Nesterenko, Nesterenko, Brugada, Brugada, Antzelevitch, 1999
Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada Syndrome are temperature dependent
Dupont, Berridge, Goldbetter, 1991
Signal-induced Ca2+ oscillations: Properties of a model based on (Ca2+)-induced Ca2+ release
Dupont, Goldbeter, 1992
Protein phosphorylation driven by intracellular calcium oscillations: A kinetic analysis
Dynamic Model of Amino Acid and Carbohydrate Metabolism in Primary Human Liver Cells
Earm, Noble, 1990
A Model of the Single Atrial Cell: Relation between Calcium Current and Calcium Release
Ebihara, Johnson, 1980
Fast sodium current in cardiac muscle: A quantitative description
Edwards, 2010
Edwards, 2010
Model of the renal medullary pericyte and its effects on the descending vasa recta.
Egli, Bertram, Sellix, Freeman, 2004
Rhythmic secretion of prolactin in rats: action of oxytocin coordinated by vasoactive intestinal polypeptide of suprachiasmatic nucleus origin
ElectrEcoBlu Systems Model
Elowitz, Leibler, 2000
A Synthetic Oscillatory Network of Transciptional Regulators
Enciso, Sontag, 2004
On the stability of a model of testosterone dynamics
Endresen, 1996
Chaos in Weakly-coupled Pacemaker Cells
Eskandari, Wright, Loo 2005
Eskandari, Wright, Loo 2005
Eskandari, Wright, Loo,
Kinetics of the Reverse Mode of the Na+/Glucose Cotransporter
Espinosa, 1998
L'Echange Na+/Ca2+ dans l'Hypertrophie Ventriculaire D'Altitude chez le Rat: Etude Electrophysiologique et Utilisation du Modele "Oxsoft Heart"
Evans, Errington, Shelly, Feeney, Chapman, Godfrey, Smith, Chappell, 2004
A mathematical model for the in vitro kinetics of the anti-cancer agent topotecan
Faber, Rudy, 2000
Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study.
Faber, Rudy, 2000 and Tong, Ghouri, Taggart, 2014
(1) Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study. (2) Computational modeling of inhibition of voltage-gated Ca channels: identification of different effects on uterine and cardiac action potentials.
Fall, Keizer, 2001
Mitochondrial Modulation of Intracellular Ca2+ Signalling
Fallon, Lauffenburger, 2000
Computational Model for Effects of Ligand/Receptor Binding Properties on Interleukin-2 Trafficking Dynamics and T Cell Proliferation Response
Farhy, Bowers, Veldhuis, 2007
Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
Farhy, Bowers, Veldhuis, 2007
Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.
Faville, Pullan, Sanders, Koh, Lloyd, Smith, 2009
Biophysically based mathematical modeling of interstitial cells of Cajal slow wave activity generated from a discrete unitary potential basis
Faville, Pullan, Sanders, Smith, 2008
A Biophysically Based Mathematical Model of Unitary Potential Activity in Interstitial Cells of Cajal
Fenton, Karma, 1998
Vortex dynamics in three-dimensional continuous myocardium with fiber rotation: Filament instability and fibrillation
Fink, Noble, Virag, Varro, Giles, 2008
Contributions of HERG K+ current to repolarization of the human ventricular action potential
Fink, Slepchenko, Loew, 1999
Determination of time-dependent inositol-1,4,5-triphosphate concentrations during calcium release in a smooth muscle cell
Fink, Slepchenko, Moraru, Watras, Schaff, Loew, 2000
An image-based model of calcium waves in differentiated neuroblastoma cells
Fitzhugh, 1961
Impulses and Physiological States in Theoretical Models of Nerve Membrane
Flynn, Green, Pedley, Boxer, Dearling, Watson, Boden, Begent, 2002
A Model-Based Approach for the Optimization of Radioimmunotherapy through Antibody Design and Radionuclide Selection
Fohlmeister, Miller, 1997
Impulse Encoding Mechanisms of Ganglion Cells in the Tiger Salamander Retina
Fox, McHarg, Gilmour, 2002
Ionic mechanism of electrical alternans
Fridlyand, Tamarina, Philipson, 2003
Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores
Fujita, Toyoshima, Uda, Ozaki, Kubota, Kuroda, 2010
Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characteristics
Gall, Susa, 1999
Effect of Na/Ca Exchange on Plateau Fraction and [Ca]i in Models for Bursting in Pancreatic Beta-Cells
Gardner, Dolnik, Collins, 1998
A theory for controlling cell cycle dynamics using a reversibly binding inhibitor
Garmendia_Torres, Goldbeter, Jacquet,
Nucleocytoplasmic oscillations of the yeast transcription factor Msn2: evidence for periodic PKA activation
Garny, Kohl, Hunter, Boyett, Noble, 2003
One-dimensional Rabbit Sinoatrial Node Models: Benefits and Limitations
Gasser, Ogden, Holzapfel, 2006
Hyperelastic modelling of arterial layers with distributed collagen fibre orientations
Gattoni 2016
Generic Cardiac Ionic Models
Gerard, Goldbeter, 2010
Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle
Gilbert, Heiner, Rosser, Fulton, Gu, Trybilo, 2007
A Case Study in Model-driven Synthetic Biology
Goforth, Bertram, Khan, Zhang, Sherman, Satin, 2002
Calcium-activated K+ Channels of Mouse Beta Cells are Controlled by Both Store and Cytoplasmic Ca2+: Experimental and Theoretical Studies
A model for the dynamics of human weight cycling
Goldbeter, 1991
A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase
Goldbeter, 1995
A model for circadian oscillations in the Drosophila period protein (PER)
Goldbeter, Dupont, Berridge, 1990
Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation
Goldbeter, Gonze, Pourquie, 2007
Sharp Developmental Thresholds Defined Through Bistability By Antagonistic Gradients of Retinoic Acid and FGF Signaling
Goldbeter, Pourquie, 2008
Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways
Gonzalez-Heydrich, Steingard, Kohane, 1994
A computer simulation of the hypothalamic-pituitary-adrenal axis
Goodwin, 1965
Oscillatory behavior in enzymatic control processes
Grandi, Pasqualini, Bers, 2009
A novel computational model of the human ventricular action potential and Ca transient
Grange, Holford, Guentert, 2001
A pharmacokinetic model to predict the PK interaction of L-dopa and benserazide in rats
Greenstein, Wu, Po, Tomaselli, Winslow, 2000
Role of the Calcium-Independent Transient Outward Current Ito1 in Shaping Action Potential Morphology and Duration
Grossman, Feinberg, Kuznetsov, Dimitrov, Paul, 1998
HIV infection: how effective is drug combination treatment?
Guccione, Mcculloch, Waldman, 1991
Gupta, Aslakson, Gurbaxani, Vernon, 2007
Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability
Guyton, Aldosterone, 2008
Description of Guyton aldosterone module
Guyton, Angiotensin, 2008
Description of Guyton angiotensin module
Guyton, Antidiuretic Hormone, 2008
Description of Guyton antidiuretic hormone module
Guyton, Atrial Natriuretic Peptide, 2008
Description of Guyton atrial natriuretic peptide module
Guyton, Autonomics, 2008
Description of Guyton autonomics module
Guyton, Capillary Dynamics, 2008
Description of Guyton capillary dynamics module
Guyton, Cardiovascular, Circulation, 2008
Description of Guyton 1992 Full Cardiovascular Circulation Model
Guyton, Circulatory Dynamics, 2008
Description of Guyton circulatory dynamics module
Guyton, Electrolytes, 2008
Description of Guyton electrolytes module
Guyton, Heart Hypertrophy or Deterioration, 2008
Description of Guyton heart hypertrophy or deterioration module
Guyton, Heart Rate and Stroke Volume, 2008
Description of Guyton heart rate and stroke volume module
Guyton, Kidney, 2008
Description of Guyton kidney module
Guyton, Muscle Blood Flow Control, 2008
Description of Guyton muscle blood flow control module
Guyton, Muscle Oxygen Delivery, 2008
Description of Guyton muscle oxygen delivery module
Guyton, Non-Muscle Blood Flow, 2008
Description of Guyton non-muscle local blood flow control module
Guyton, Non-Muscle Oxygen Delivery, 2008
Description of Guyton non-muscle oxygen delivery module
Guyton, Pulmonary Fluid Dynamics, 2008
Description of Guyton pulmonary fluid dynamics module
Guyton, Pulmonary Oxygen Uptake, 2008
Description of Guyton pulmonary oxygen uptake module
Guyton, Red Cells and Viscosity, 2008
Description of Guyton red cells and viscosity module
Guyton, Stress Relaxation, 2008
Description of Guyton stress relaxation module
Guyton, Thirst, Drinking and Salt Appetite, 2008
Description of guyton thirst, drinking and salt appetite module
Guyton, Volume Receptors, 2008
Description of Guyton volume receptors module
H+-ATPase (V-type) Model
Hai, Murphy, 1988
Cross-bridge phosphorylation and regulation of latch state in smooth muscle
Halloy, Bernard, Loussouarn, Goldbeter, 2002
The Follicular Automaton Model: Effect of Stochasticity and of Synchronization of Hair Cycles
Hatakeyama, Shirouzu, Yokoyama, Konagaya, Kimura, Naka, Kawasaki, Yumoto, Ichikawa, Kim, Saito, Saeki, 2003
A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling
Hatzimanikatis, Lee, Bailey, 1999
A mathematical description of regulation of the G1-S transition of the mammalian cell cycle
Haugh, 2004
Mathematical model of human growth hormone (hGH)-stimulated cell proliferation explains the efficacy of hGH variants as receptor agonists or antagonists
Heinze, Keener, Midgley, 1998
A mathematical model of luteinizing hormone release from ovine pituitary cells in perifusion
Heldt, Shim, Kamm, Mark, 2002
Computational modeling of cardiovascular response to orthostatic stress
Herz, Bonhoeffer, Anderson, May, Nowak, 1996
Viral Dynamics in vivo: Limitations on estimates of intracellular delay and virus decay
Heyd, Drew, 2003
A mathematical model for elongation of a peptide chain
Hilgemann, Noble, 1987
Excitation-contraction coupling and extracellular calcium transients in rabbit atrium: reconstruction of basic cellular mechanisms
Hinch, Greenstein, Tanskanen, Xu, Winslow, 2004
A Simplified Local Control Model of Calcium-Induced Calcium Release in Cardiac Ventricular Myocytes
Hodgkin, Huxley, 1952
A quantitative description of membrane current and its application to conductance and excitation in nerve
Hoefnagel, Starrenburg, Martens, Hugenholtz, Kleerebezem, Van Swam, Bongers, Westerhoff, Snoep, 2002
Metabolic engineering of lactic acid bacteria, the combined approach: kinetic modelling, metabolic control and experimental analysis
Holmes, 2006
Teaching from classic papers: Hill's model of muscle contraction
Hornberg, Binder, Bruggeman, Schoeberl, Heinrich, Westerhoff, 2005
Control of MAPK signalling: from complexity to what really matters
Houart, Dupont, Albert, 1999
Bursting, Chaos and birhythmicity Originating from Self-modulation of the Inositol 1,4,5-triphosphate Signal in a Model for Intracellular Ca2+ Oscillations
Huang, Ferrell, 1996
Ultrasensitivity in the mitogen-activated protein kinase cascade
Hund, Rudy, 2004
Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model
Hunter, McCulloch, ter Keurs, 1998
Modelling the mechanical properties of cardiac muscle
Hunter, McNaughton, Noble, 1975
Analytical models of propagation in excitable cells
Hunter, Smaill, Hunter, 1995
A pole-zero constitutive law for myocardium
Hynne, Dano, Sorensen, 2001
Full-scale model of glycolysis in Saccharomyces cerevisiae
Iancu, Jones, Harvey, 2007
Compartmentation of cAMP signaling in cardiac myocytes: a computational study
Iber, Maini, 2002
A Mathematical Model for Germinal Centre Kinetics and Affinity Maturation
Improvement of metabolic performance of primary hepatocytes in hyperoxic cultures by vitamin C in a novel small-scale bioreactor
Inada, Hancox, Zhang, Boyett, 2009
One-dimensional mathematical model of the atrioventricular node including atrio-nodal, nodal, and nodal-his cells
International SI Units, 2006
International SI Units, 2006
Iribe, Kohl, Noble, 2006
Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca2+ handling and interval-force relations: a modelling study.
Irvine, Jafri, Winslow, 1999
Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation
Itskov, Ehret, Mavrilas, 2006
A Polyconvex Anisotropic Strain-Energy Function for Soft Collagenous Tissues
Iyer, Hajjar, Armoundas, 2007
Mechanisms of Abnormal Calcium Homeostasis in Mutations Responsible for Catecholaminergic Polymorphic Ventricular Tachycardia
Iyer, Mazhari, Winslow, 2004
A computational model of the human left-ventricular epicardial myocyte
Izakov, Katsnelson, Blyakhman, Markhasin, Shkylar, 1991
Cooperative Effects Due to Calcium Binding by Troponin and Their Consequences for Contraction and Relaxation of Cardiac Muscle Under Various Conditions of Mechanical Loading
Jafri, Rice, Winslow, 1998
Cardiac Ca2+ Dynamics: The Roles of Ryanodine Receptor Adaptation and Sarcoplasmic Reticulum Load
Jelic, Cupic, Kolar-Anic, 2005
A Hypothalamic-Pituitary-Adrenal System Model: Full Model
Joseph, Zavros, Merchant, Kirschner, 2003
A model for integrative study of human gastric acid secretion
Karagiannis, Popel, 2004
A theoretical model of type I collagen proteolysis by matrix metalloproteinase (MMP) 2 and membrane type 1 MMP in the presence of tissue inhibitor of metalloproteinase 2
Karagiannis, Popel, 2006
Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: insights from a computational model
Katsnelson, Nikitina, Chemla, Solovyova, Coirault, Lecarpentier, Markhasin, 2004
Influence of viscosity on myocardium mechanical activity: a mathematical model
Keener, 2001
Diffusion Induced Oscillatory Insulin Secretion
Keizer, Levine, 1996
Ryanodine Receptor Adaptation and Ca2+-Induced Ca2+ Release-Dependent Ca2+ Oscillations
Kesmir, De Boer, 1999
A Mathematical Model on Germinal Center Kinetics and Termination
Kholodenko, Demin, Moehren, Hoek, 1999
Quantification of short term signalling by the epidermal growth
Kirschner, Panetta, 1998
Modeling immunotherapy of the tumor-immune interaction
Kirschner, Webb, 1996
A Model For Treatment Strategy In The Chemotherapy Of AIDS
Kneller, Ramirez, Chartier, Courtemanche, Nattel, 2002
Time-dependent transients in an ionically based mathematical model of the canine atrial action potential
Koivumaki, Takalo, Korhonen, Tavi, Weckstrom, 2009
Modelling Sarcoplasmic Reticulum Calcium APTase and its Regulation in Cardiac Myocytes
Komarova, 2005
Mathematical model of paracrine interactions between osteoclasts and osteoblasts predicts anabolic action of parathyroid hormone on bone
Komarova, Smith, Dixon, Sims, Wahl, 2003
Mathematical model predicts a critical role for osteoclast autocrine regulation in the control of bone remodeling
Komarova, Wodarz, 2003
Evolutionary Dynamics of Mutator Phenotypes in Cancer: Implications for Chemotherapy
Kongas, van Beek, 2001
Creatine kinase in energy metabolic signaling in muscle
Korakianitis, Shi, 2006
Numerical simulation of cardiovascular dynamics with healthy and diseased heart valves
Korzeniewski, Zoladz, 2001
A model of oxidative phosphorylation in mammaliam skeletal muscle
Kroll, 2000
Parathyroid hormone temporal effects on bone formation and resorption
Kurata, Hisatome, Imanishi, Shibamoto, 2002
Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell
Kyrylov, Severyanova, Vieira, 2005
Modeling robust oscillatory behavior of the hypothalamic-pituitary-adrenal axis
Lambeth, Kushmerick, 2002
A computational model for glycogenolysis in skeletal muscle
Laminar structure of the Heart: A mathematical model.
Landesberg, Sideman, 1994
Mechanical regulation of cardiac muscle by coupling calcium kinetics with cross-bridge cycling: a dynamic model
Latency correlates with period in a model for signal-induced Ca2l oscillations based on Ca"2-induced Ca2+ release
LeBeau, Robson, McKinnon, Donald, Sneyd, 1997
Generation of Action Potentials in a Mathematical Model of Corticotrophs
LeBeau, Yule, Groblewski, Sneyd, 1999
Agonist-dependent Phosphorylation of the Inositol 1,4,5-Triphosphate Receptor
Leloup, Goldbeter,
A Model for Circadian Rhythms in Drosophila Incorporating the Formation of a Complex between the PER and TIM Proteins
Leloup, Goldbeter, 2003
Toward a detailed computational model for the mammalian circadian clock
Leloup, Goldbeter, 2004
Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms
Leloup, Gonze, Goldbeter, 1999
Limit Cycle Models for Circadian Rhythms Based on Transcriptional Regulation in Drosophila and Neurospora
Lemaire, Tobin, Greller, Cho, Suva, 2004
Modeling the interactions between osteoblast and osteoclast activities in bone remodeling
Lemon, Gibson, Bennett, 2003
Metabotropic receptor activation, desensitization and sequestration-I: modelling calcium and inositol 1,4,5-trisphosphate dynamics following receptor activation
Lenbury, Pacheenburawana, 1991
Modelling fluctuation phenomena in the plasma cortisol secretion system in normal man
Lenbury, Pornsawad, 2005
A delay-differential equation model of the feedback-controlled hypothalamus-pituitary-adrenal axis in humans
Lenbury, Ruktamatakul, Amornsamarnkul, 2001
Modeling insulin kinetics: responses to a single oral glucose administration or ambulatory-fed conditions
Li, Bertram, Rinzel, 1996
Modeling N-methyl-D-aspartate-induced bursting in dopamine neurons
Li, Kuang, Mason, 2006
Modeling the glucose-insulin regulatory system and ultradian insulin secretory oscillations with two explicit time delays
Li, Rinzel, 1994
Equations for InsP3 Receptor-mediated [Ca2+]i Oscillations Derived from a Detailed Kinetic Model: A Hodgkin-Huxley Like Formalism
Li, Smith, 2009
Library of metabolic components in CellML
Lindblad, Murphey, Clark, Giles, 1996
A Model of the Action Potential and Underlying Membrane Currents in a Rabbit Atrial Cell
Liu, Hu, Peng, Liu, 1999
A dynamical model for the pulsatile secretion of the hypothalamo-pituitary-adrenal axis
Livshitz, Rudy, 2007
Regulation of Ca2+ and electrical alternans in cardiac myocytes: role of CAMKII and repolarizing currents
Lockwood, Ewy, Hermann, Holford, 2006
Application of clinical trial simulation to compare proof-of-concept study designs for drugs with a slow onset of effect; an example in Alzheimer's disease
Lokta, Volterra,
Predator-prey dynamics
Lovell, Cloherty, Celler, Dokos, 2004
A gradient model of cardiac pacemaker myocytes
Lumped-parameter cardiovascular model with Westkessel after-load
Lumped-parameter model for the systemic circulation
Luo, Rudy, 1991
A Model of the Ventricular Cardiac Action Potential. Depolarization, repolarization and their interaction
Luo, Rudy, 1994
A Dynamic Model of the Cardiac Ventricular Action Potential I. Simulations of Ionic Currents and Concentration Changes
Luo, Rudy, 1994
A Dynamic Model of the Cardiac Ventricular Action Potential I. Simulations of Ionic Currents and Concentration Changes
MacGregor, Leng, 2005
Modelling the hypothalamic control of growth hormone secretion.
Mackenzie, Loo, Panayotova-Heiermann and Wright, 1996
Mackenzie, Loo, Panayotova-Heiermann and Wright, 1996
Mackenzie, Loo, Panayotova-Heiermann, Wright,
Biophysical Characteristics of the Pig Kidney Na/Glucose Cotransporter SGLT2 Reveal a Common Mechanism for SGLT1 and SGLT2
Magnus, Keizer, 1997
Minimal Model of beta-cell mitochondrial Ca2+ handling
Magnus, Keizer, 1998
Model of beta_cell mitochondrial calcium handling and electrical activity. I. Cytoplasmic variables
Mahajan, Karma, Garfinkel, Qu, Weiss, Shiferaw, Sato, Baher, Olcese, Xie, Yang, Chen, Restrepo, 2008
A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates
Maldonado, Borchers, Findeisen, Allgower, 2006
Mathematical modeling and analysis of force induced bone growth
Maleckar, Greenstein, Trayanova, Giles, 2009
Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium
Maltsev, Lakatta, 2009
Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model.
Maly, Wiley, Lauffenburger, 2004
Self-Organization of Polarized Cell Signaling via Autocrine Circuits: Computational Model Analysis
Marhl, Haberichter, Brumen, Heinrich, 2000
Complex calcium oscillations and the role of mitochondria and cytosolic proteins
Marhl, Schuster, Brumen, Heinrich, 1997
Modelling the interrelations between calcium oscillations and ER membrane potential oscillations
Martinov, Vitvitsky, Mosharov, Banerjee, Ataullakhanov, 2000
A Substrate Switch: A New Mode of Regulation in the Methionine Metabolic Pathway
Martins, Mendes, Coreiro, Freire, 2001
In situ kinetic analysis of glyoxalase I and glyoxalase II in Saccharomyces cerevisiae
Marwan, 2003
Theory of Time-Resolved Somatic Complementation and Its Use to Explore the Sporulation Control Network in Physarum polycephalum
Mathematical modeling of mechanically modulated rhythm disturbances in homogeneous and heterogeneous myocardium with attenuated activity of na+ -k+ pump
Matsuoka, Sarai, Kuratomi, Ono, Noma, 2003
Role of individual ionic current systems in ventricular cells hypothesized by a model study
Maurya, Bornheimer, Venkatasubramanian, Subramaniam, 2005
Reduced-order modelling of biochemical networks: application to the GTPase-cycle signalling module
Mazhari, Greenstein, Winslow, Marban, Nuss, 2001
Molecular Interactions Between Two Long-QT Syndrome Gene Products, HERG and KCNE2, Rationalized by In Vitro and In Silico Analysis
McAllister, Noble, Tsien, 1975
Reconstruction of the electrical activity of cardiac Purkinje fibres.
McKenzie, Sneyd, 1998
On the Formation and Breakup of Spiral Waves of Calcium
McLean, Su, van den Bogert, 2003
Development and Validation of a 3-D Model to Predict Knee Joint Loading During Dynamic Movement
Mears, Sheppard, Atwater, Rojas, Bertram, Sherman, 1997
Evidence That Calcium Release-activated Current Mediates the Biphasic Electrical Activity of Mouse Pancreatic Beta-Cells
Michailova, McCulloch, 2001
Model study of ATP and ADP buffering, transport of Ca2+ and Mg2+, and regulation of ion pumps in ventricular myocyte
Michailova, Saucerman, Belik, McCulloch, 2005
Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+
Miftakhov, Abdusheva, Christensen, 1999
Numerical Simulation of Motility Patterns of the Small Bowel. I. Formulation of a Mathematical Model
Mijailovich, Butler, Fredburg, 2000
Perturbed Equilibria of Myosin Binding in Airway Smooth Muscle: Bond-Length Distributions, Mechanics and ATP Metabolism
Mikane, Suga, Araki, Kohno, Nakayama, Suzuki, Shimuzi, Matsubara, Hirakawa, Takaki, 1997
Mechanism of Constant Contractile Efficiency Under Cooling Intropy of Myocardium: Simulation
Mitchell, Schaeffer, 2003
A two-current model for the dynamics of cardiac membrane
Mitochondria regulate the amplitude of simple and complex calcium oscillations
Mittler, Sulzer, Neumann, Perelson, 1998
Influence of delayed viral production on viral dynamics in HIV-1 infected patients
Mlcek, Neumann, Kittnar, Novak, 2001
Mathematical Model of the Electromechanical Heart Contractile System - Regulatory Subsystem Physiological Considerations
Model of a rabbit Purkinje cell
Modelling Hypertrophic IP3 Transients in the Cardiac Myocyte (Cooling, Hunter, Crampin, 2007)
Models for the OpenCOR and PMR tutorial by Peter Hunter
Mohr, Taylor, Newell, 2008
Mohr, Taylor, Newell, 2008
Moore, Li, 2004
A mathematical model for chronic myelogenous leukemia (CML) and T cell interaction
Moore, Li, 2004
A mathematical model for chronic myelogenous leukemia (CML) and T cell interaction
Morris, Lecar, 1981
Voltage oscillations in the barnacle giant muscle fiber
Mosekilde, Lading, Yanchuk, Maistrenko, 2001
Bifurcation structure of a model of bursting pancreatic cells
Moss, Kazmierczak, Kirley, Harris, 2009
A computational model for emergent dynamics in the kidney
mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: A population-based simulation study
Muller, Obeyesekere, Mills, Ram, 2008
Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R
Myocardial contractility and regional work throughout the cardiac cycle using FEM and MRI
Na+/H+ Exchanger (NHE3) Model
Na+/HCO3- Cotransporter
Na+/K+-ATPase (sodium-potassium pump)
Nagano, Gerritsen, 2001
Effects of Neuromuscular Strength Training on Vertical Jumping Performance - A Computer Simulation Study
Nagerl, Novo, Mody, Vergara, 2000
Binding Kinetics of Calbindin-D28k Determined by Flash Photolysis of Caged Ca2+
Nash, Panfilov, 2004
Electromechanical model of excitable tissue to study reentrant cardiac arrhythmias
Nazaret, Heiske, Thurley and Mazat, 2009
Mitochondrial energetic metabolism: a simplified model of TCA cycle with ATP production (unscaled version)
Nelson, Murray, Perelson, 2000
A model of HIV-1 pathogenesis that includes an intracellular delay
Nelson, Perelson, 1995
Modeling defective interfering virus therapy for AIDS: conditions for DIV survival
Neumann, Lam, Dahari, Gretch, Wiley, Layden, Perelson, 1998
Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-alpha Therapy
Nevo, Golding, Neumann, Schwartz, Akselrod, 2004
Nevo et al.'s 2004 mathematical model of autoimmunity.
Niederer, Hunter, Smith, 2006
A quantitative analysis of cardiac myocyte relaxation: a simulation study
Niederer, Smith, 2007
A Mathematical Model of the Slow Force Response to Stretch in Rat Ventricular Myocytes
Noble, 1962
A Modification of the Hodgkin-Huxley Equations Applicable to Purkinje Fibre Action and Pace-Maker Potentials
Noble, DiFrancesco, Denyer, 1989
Ionic Mechanisms in Normal and Abnormal Cardiac Pacemaker Activity
Noble, Noble, 1984
A Model of Sino-Atrial Node Electrical Activity Based on a Modification of the DiFrancesco-Noble (1984) Equations
Noble, Noble, 2001
Remodelling of Calcium Dynamics in Guinea-Pig Ventricular Cells
Noble, Noble, Bett, Earm, Ho, So, 1991
The Role of Sodium-Calcium Exchange During the Cardiac Action Potential
Noble, Varghese, Kohl, Noble, 1998
Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes.
Noble, Varghese, Kohl, Noble, 1998
Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes.
Novak, Csikasz-Nagy, Gyorffy, Chen, Tyson, 1998
Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions
Novak, Pataki, Ciliberto, Tyson, 2001
Mathematical model of the cell division cycle of fission yeast
Novak, Tyson, 1993
Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos.
Novak, Tyson, 1997
Modeling the control of DNA replication in fission yeast
Novak, Tyson, 2004
A model for restriction point control of the mammalian cell cycle
Nowak, Bangham, 1996
Population dynamics of immune responses to persistent viruses
Nygren, Fiset, Firek, Clark, Lindblad, Clark, Giles, 1998
Mathematical Model of an Adult Human Atrial Cell: The Role of K+ Currents in Repolarization
Obeyesekere, Zimmerman, Tecarro, Auchmuty, 1999
A model of cell cycle behavior dominated by kinetics of a pathway stimulated by growth factors
Olsen, Hauser, Kummer, 2003
Mechanism of protection of peroxidase activity by oscillatory dynamics
On the encoding and decoding of calcium signals in hepatocytes
Oomens, Maenhout, van Oijen, Drost, Baaijens, 2003
Finite element modelling of contracting skeletal muscle
Ostby, Omholt, Oyehaug, Einevoll, Nagelhus, Plahte, Zeuthen, Voipio, Lloyd, Ottersen, 2008
Astrocytic processes explaining neural-activity-induced shrinkage of extraneuronal space
Overgaard, Holford, Rytved, Madsen, 2007
PKPD model of interleukin-21 effects on thermoregulation in monkeys--application and evaluation of stochastic differential equations
Oyehaug, Ostby, Lloyd, Omholt, Einevoll, 2011
Dependence of spontaneous neuronal firing and depolarization block on astroglial membrane processes: Fig 2B
Oyehaug, Ostby, Lloyd, Omholt, Einevoll, 2011
Dependence of spontaneous neuronal firing and depolarization block on astroglial membrane processes: Fig 2A
Palecek, Horwitz, Lauffenburger, 1999
Kinetic Model for Integrin-mediated Adhesion Release During Cell Migration
Pandit, Clark, Giles, Demir, 2001
A Mathematical Model of Action Potential Heterogeneity in Adult Rat Left Ventricular Myocytes
Pandit, Giles, Demir, 2003
A Mathematical Model of the Electrophysiological Alterations in Rat Ventricular Myocytes in Type-I Diabetes
Panerai, 1980
A Model of Cardiac Muscle Mechanics and Energetics
Parent, Supplisson, Loo, Wright,
Electrogenic Properties of the Cloned Na+/Glucose Cotransporter: II. A Transport Model under Nonrapid Equilibrium Conditions
Pasek, Simurda, Christe, 2006
The functional role of cardiac T-tubules explored in a model of rat ventricular myocytes
Pasek, Simurda, Orchard, Christe, 2008
A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system
Pedersen, Bertram, Sherman, 2005
Intra- and inter-islet synchronization of metabolically driven insulin secretion
Perelson, Kirschner, de Boer, 1993
Dynamics of HIV infection of CD4+ T cells
Perelson, Neumann, Markowitz, Leonard, Ho, 1996
HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time
Phillips, Robinson, 2007
A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system
Phillips, Robinson, 2008
Sleep deprivation in a quantitative physiologically based model of the ascending arousal system
Pivonka, Zimak, Smith, Gardiner, Dunstan, Sims, Martin, Mundy, 2008
Model structure and control of bone remodeling: a theoretical study
Plant, 1981
Bifurcation and resonance in a model for bursting nerve cells
Potter, Greller, Cho, Nuttall, Stroup, Suva, Tobin, 2005
Response to continuous and pulsatile PTH dosing: a mathematical model for parathyroid hormone receptor kinetics
Potter, Zager, Barton, 2006
Mathematical model for the androgenic regulation of the prostate in intact and castrated adult male rats.
Priebe, Beuckelmann, 1998
Simulation Study of Cellular Electrical Properties in Heart Failure
Proctor, Soti, Boys, Gillespie, Shanley, Wilkinson, Kirkwood, 2005
Modelling the actions of chaperones and their role in ageing.
Proctor, Tsiringotis, Gray, 2007
An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline
Puglisi, Bers, 2001
LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport
Purvis, Butera, 2005
Ionic Current Model of a Hypoglossal Motoneuron
Purvis, Smith, Koizumi, Butera, 2007
Intrinsic Bursters Increase the Robustness of Rythm Generation in an Excitatory Network
Qu, MacLellan, Weiss, 2003
Dynamics of the Cell Cycle: Checkpoints, Sizers, and Timers
Ralser, Lehrach, Krobitsch, Wamelink, Kowald, Gerisch, Heeren, Struys, Klipp, Jakobs, Breitenbach, 2007
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
Ramirez, Nattel, Courtemanche, 2000
Mathematical analysis of canine atrial action potentials: rate, regional factors, and electrical remodeling
Rangamani, Sirovich, 2007
Survival and apoptotic pathways initiated by TNF-alpha: modeling and predictions
Raposo, Sobrinho, Ferreira, 2002
A minimal mathematical model of calcium homeostasis
Rattananakul, Lenbury, Krishnamara, Wollkind, 2003
Modeling of bone formation and resorption mediated by parathyroid hormone: response to estrogen/PTH therapy
Razumova, Bukatina, Campbell, 1999
Stiffness-distortion sacromere model for muscle stimulation
Razumova, Bukatina, Campbell, 2000
Different Myofilament Nearest-Neighbor Interactions Have Distinctive Effects on Contractile Behavior
Reconstruction of the action potential of ventricular myocardial fibres
Reconstruction of the action potential of ventricular myocardial fibres
Reconstruction of the action potential of ventricular myocardial fibres, with modifications to demonstrate uncertainty.
Reed, Nijhout, Sparks, Ulrich, 2004
A mathematical model of the methionine cycle
Reidl, Borowski, Sensse, Starke, Zapotocky, Eiswirth, 2006
Model of Calcium Oscillations Due to Negative Feedback in Olfactory Cilia
Renal Na+/H+ antiporter (NHE3) model
Renal SGLT1 model
Revilla, Garcia-Ramos, 2003
Fighting a virus with a virus: a dynamic model for HIV-1 therapy
Riccobene, Omann, Linderman, 1999
Modeling Activation and Desensitisation of G-Protein Coupled Receptors Provides Insight into Ligand Efficacy
Rice, Jafri, Winslow, 2000
Modeling short-term interval-force relations in cardiac muscle
Rice, Wang, Bers, de Tombe, 2008
Approximate model of cooperative activation and crossbridge cycling in cardiac muscle using ordinary differential equations
Rice, Winslow, Hunter, 1999
Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responses (model 1)
Rice, Winslow, Jafri, 1999
Modeling Gain and Gradedness of Ca2+ Release in the Functional Unit of the Cardiac Diadic Space
Riemer, Sobie, Tung, 1998
Stretch-induced changes in arrhythmogenesis and excitability in experimentally based heart cell models
Rivlin, Saunders, 1951
Large Elastic Deformations of Isotropic Materials. VII. Experiments on the Deformation of Rubber
Rogers, McCulloch, 1994
A collocation--Galerkin finite element model of cardiac action potential propagation
Romond, Rustici, Gonze, Goldbeter, 1999
Alternating Oscillations and Chaos in a Model of Two Coupled Biochemical Oscillators Driving Successive Phases of the Cell Cycle
Rong, Perelson, 2009
Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy
Roux, Noble, Noble, Marhl, 2006
Modelling of calcium handling in airway myocytes
Rubin, Shevtsova, Ermentrout, Smith, Rybak, 2009
Multiple rhythmic states in a model of the respiratory central pattern generator
Sachse, Glanzel, Seemann, 2003
Modeling of Protein Interactions Involved in Cardiac Tension Development
Sachse, Moreno, Abildskov, 2008
Electrophysiological Modeling of Fibroblasts and Their Interaction with Myocytes
Saftenku, Williams, Sitsapesan, 2001
Markovian Models of Low and High Activity Levals of Cardiac Ryanodine Receptors
Sakmann, Spindler, Bryant, Linz, Noble, 2000
Distribution of a persistent sodium current across the ventricular wall in guinea pigs.
Salem, Saidel, Stanley, Cabrera, 2002
Mechanistic Model of Myocardial Energy Metabolism Under Normal and Ischemic Conditions
Sarai, Matsuoka, Kuratomi, Ono, Noma, 2003
Role of individual ionic current systems in the SA node hypothesized by a model study
Sarkar, Lauffenburger, 2003
Cell-Level Pharmacokinetic Model of Granulocyte Colony-Stimulating Factor: Implications for Ligand Lifetime and Potency in Vivo
Saucerman, Bers, 2008
Calmodulin Mediates Differential Sensitivity of CAMKII and Calcineurin to Local Ca2+ in Cardiac Myocytes
Saucerman, Brunton, Michailova, McCulloch, 2003
Modeling beta-adrenergic control of cardiac myocyte contractility in silico
Saucerman, McCulloch, 2004
Mechanistic systems models of cell signaling networks: a case study of myocyte adrenergic regulation
Schenzle, 1994
A model for AIDS pathogenesis
Schlosser, Selgrade, 2000
A model of gonadotropin regulation during the menstrual cycle in women: qualitative features
Schmid, Nash, Young, Hunter, 2006
Myocardial Material Parameter Estimation - A Comparative Study for Simple Shear
Schneider, Shimayoshi, Amano, Matsuda, 2006
Mechanism of the Frank-Starling law-- A simulation study with a novel cardiac muscle contraction model that includes titin and tropomyosin
Schoeberl, Eichler-Jonsson, Gilles, Muller, 2002
Computational Modeling of the Dynamics of the MAP Kinase Cascade Activated by Surface and Internalized EGF Receptors.
Schuster, Beny, Meister, 2003
Modelling the electrophysiological endothelial cell response to bradykinin
Sedaghat, Sherman, Quon, 2002
A mathematical model of metabolic insulin signaling pathways
Seemann, Sachse, Weib, Dossel, 2003
Quantitative Reconstruction of Cardiac Electromechanics in Human Myocardium: Regional Heterogeneity
Shannon, Wang, Puglisi, Weber, Bers, 2004
A Mathematical Treatment of Integrated Ca Dynamics within the Ventricular Myocyte
Shaw, Chase, Starfinger, Smith, Hann, Desaive, Ghuysen, 2007
Modeling the Cardiovascular System
Shaw, Rudy, 1997
Electrophysiological effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration
Shi, Korakianitis, Bowles, 2007
Numerical simulation of cardiovascular dynamics with different types of VAD assistance
Shi, Lawford, Hose, 2010
Numerical Modeling of Hemodynamics with Pulsatile Impeller Pump Support
Shiferaw, Watanabe, Garfinkel, Weiss, Karma, 2003
Model of Intracellular Calcium Cycling in Ventricular Myocytes
Shorten, O'Callaghan, Davidson, Soboleva, 2007
A mathematical model of fatigue in skeletal muscle force contraction
Shorten, Robson, McKinnon, Wall, 2000
CRH-induced Electrical Activity and Calcium Signalling in Pituitary Corticotrophs
Shorten, Wall, 2000
A Hodgkin-Huxley Model Exhibiting Bursting Oscillations
Shrestha, Hollot, Chipkin, Schmitt, Chait, 2010
A mathematical model of parathyroid hormone response to acute changes in plasma ionized calcium concentration in humans
Siebert, Rode, Herzog, Till, Blickhan, 2008
Nonlinearities make a difference: comparison of two common Hill-type models with real muscle
Simple 2nd order linear ODE, a classical mathematical model
Sine approximations in CellML
Skouibine, Trayanova, Moore, 1999
Anode/cathode make and break phenomena in a model of defibrillation
Smith, 1980
Hypothalamic regulation of pituitary secretion of luteinizing hormone. II. Feedback control of gonadotropin secretion
Smith, Abdala, Koizumi, Rybak, Paton, 2007
Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms
Smith, Chase, Nokes, Shaw, Wake, 2004
Minimal haemodynamic system model including ventricular interaction and valve dynamics.
Smith, Crampin, 2004
Development of models of active ion transport for whole-cell modelling: cardiac sodium-potassium pump as a case study
Sneyd, Dufour, 2002
A dynamic model of the type-2 inositol triphosphate receptor
Sneyd, Tsaneva-Atanasova, Bruce, Straub, Giovannucci, Yule, 2003
A Model of Calcium Waves in Pancreatic and Parotid Acinar Cells
Sneyd, Tsaneva-Atanasova, Yule, Thompson, Shuttleworth, 2004
Sneyd et al.'s 2004 mathematical model for Ca2+ oscillations and their control by membrane fluxes.
Sneyd, Wetton, Charles, Sanderson, 1995
Intercellular calcium waves mediated by diffusion of inositol trisphosphate: a two-dimensional model
Snyder, Palmer, Moore, 2000
A Mathematical Model of Cardiocyte Ca2+ Dynamics with a Novel Representation of Sarcoplasmic Reticular Ca2+ Control
Sobie, Dilly, dos Santos Cruz, Lederer, Jafri, 2002
Termination of Cardiac Ca2+ Sparks: An Investigative Mathematical Model of Calcium-Induced Calcium Release
Soboleva, Vetharaniam, Nixon, Montenegro, Pearson, Sneyd, 2005
Mathematical modelling of prolactin-receptor interaction and the corollary for prolactin receptor gene expression in skin
Spiro, Parkinson, Othmer, 1997
A model of excitation and adaptation in bacterial chemotaxis
Spronck, 2012
Sriram, Bernot, Kepes, 2007
A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle
St Hilaire, Gronfier, Zeitzer, Klerman, 2007
A physiologically based mathematical model of melatonin including ocular light suppression and interactions with the circadian pacemaker
Standard Virtual Parts Template Library 200906
Starbuck, Wiley, Lauffenburger, 1990
Epidermal Growth Factor Binding and Trafficking Dynamics in Fibroblasts: Relationship to Cell Proliferation
Stern, Song, Sham, Yang, Boheler, Rios, 1999
Local Control Models of Cardiac Excitation-Contraction Coupling A Possible Role for Allosteric Interactions between Ryanodine Receptors
Stewart, Aslanidi, Noble, Noble, Boyett, Zhang, 2009
Mathematical models of the electrical action potential of Purkinje fibre cells
Stilianakis, Dietz, Schenzle, 1997
Analysis of a Model for the Pathogenesis of AIDS
Surkis, Peskin, Tranchina, Leonard, 1998
Recovery of Cable Properties Through Active and Passive Modeling of Subthreshold Membrane Responses From Laterodorsal Tegmental Neurons
Sveiczer, Csikasz-Nagy, Gyorffy, Tyson, Novak, 2000
Modeling the fission yeast cell cycle: quantized cycle times in wee1- cdc25Delta mutant cells.
Swanson, True, Lin, Buhler, Vessella, Murray, 2001
A Quantitative Model for the Dynamics of Serum Prostate-Specific Antigen as a Marker for Cancerous Growth
Switching from Simple to Complex Oscillations in Calcium Signaling
Synchronized Scene Viewer
Tabak, Mascagni, Bertram, 2010
Mechanism for the Universal Pattern of Activity in Developing Neuronal Networks
Tabak, Toporikova, Freeman, Bertram, 2007
Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents
Ten Tusscher, Noble, Noble, Panfilov, 2004
A model for human ventricular tissue
ten Tusscher, Panfilov, 2006
Alternans and spiral breakup in a human ventricular tissue model.
Terkildsen, Niederer, Crampin, Hunter, Smith, 2008
Using Physiome standards to couple cellular functions for rat cardiac excitation-contraction
Testing linkage between SVG images and CellML/SED-ML documents
Testing linkage between SVG images and CellML/SED-ML documents
Teusink, Westerhoff, Snoep, Passarge, Reijenga, Esgalhado, van der Weijden, Schepper, Walsh, Bakker, van Dam, 2000
Can yeast glycolysis be understood in terms of in vitro kinetics of the constituent enzymes? Testing biochemistry.
Tham, Wang, Soo, Lee, Lee, Yong, Goh, Holford, 2008
A pharmacodynamic model for the time course of tumor shrinkage by gemcitabine + carboplatin in non-small cell lung cancer patients
The Glucose-induced Switch Between Glycogen Phosphorylase and Glycogen Synthase in the Liver: Outlines of a Theoretical Approach
The Lorenz Attractor, a classical mathematical model
The Noble (1962) cell model
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The ORd human ventricular action potential model
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Modelling the Insulin-Glucose Feedback System: The Significance of Pulsatile Insulin Secretion
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Topp, Promislow, de Vries, Miura, Finegood, 2000
A Model of Beta-Cell Mass, Insulin, and Glucose Kinetics: Paythways to Diabetes
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A Thermodynamic Model of the Cardiac Sarcoplasmic/Endoplasmic Ca(2+) (SERCA) Pump
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A metabolite-sensitive, thermodynamically-constrained model of cardiac cross-bridge cycling: Implications for force development during ischemia
Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes
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Modeling the Cell Division Cycle:cdc2 and Cyclin Interactions
Tyson, Hong, Thron, Novak, 1999
A Simple Model of Circadian Rhythms Based on Dimerization and Proteolysis of PER and TIM
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Adenine nucleotide-creatine-phosphate module in myocardial metabolic system explains fast phase of dynamic regulation of oxidative phosphorylation
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Computer simulation of arrhythmias in a network of coupled excitable elements
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Amplitude-Dependent Spike-Broadening and Enhanced Ca2+ Signaling in GnRH-Secreting Neurons
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A multiscale model to investigate circadian rhythmicity of pacemaker neurons in the suprachiasmatic nucleus
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In Vivo Dynamics of the Pentose Phosphate Pathway in Saccharomyces cerevisiae
Vempati, Karagiannis, Popel, 2007
A Biochemical Model of Matrix Metalloproteinase 9 Activation and Inhibition
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Ventricular mechanics in diastole: material parameter sensitivity.
Viewing the PCA visualiser for the Medrano-Gracia model
Vilar, Jansen, Sander, 2006
Signal processing in the TGF-beta superfamily ligand-receptor network
Vilar, Kueh, Barkai, Leibler, 2002
Mechanisms of noise-resistance in genetic oscillators
Vinnakota, Kemp, Kushmeric, 2006
Dynamics of Muscle Glycogenolysis Modeled with pH Time Course Computation and pH-Dependent Reaction Equilibria and Enzyme Kinetics
Vinnakota, Rusk, Palmer, Shankland, Kushmeric, 2010
Common Phenotype of Resting Mouse EDL and SOL Muscles: EDL
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Viswanathan, Shaw, Rudy, 1999
Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study (Midmyocardial Cell Model)
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Insulin receptor binding kinetics: modeling and simulation studies
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A quantitative kinetic model for ATP-induced intracellular Ca2+ oscillations
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Mathematical modeling and qualitative analysis of insulin therapies
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Effect of riluzole on action potential in cultured human skeletal muscle cells
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Mathematical model of the neonatal mouse ventricular action potential
Warashina, Ogura, 2004
Modeling of simulation-secretion coupling in a chromaffin cell
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Mathematical modelling of calcium wave propagation in mammalian airway epithelium: evidence for regenerative ATP release
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Macrophage Dynamics in Diabetic Wound Healing
Waugh, Sherratt, 2007
Modeling the effects of treating diabetic wounds with engineered skin substitutes
Webb, Sherratt, Fish, 2002
Cells behaving badly: a theoretical model for the Fas/FasL system in tumour immunology
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Mathematical analysis of antiretroviral therapy aimed at HIV-1 eradication or maintenance of low viral loads
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A mathematical model of the inner medullary collecting duct of the rat: acid/base transport
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A mathematical model of the outer medullary collecting duct of the rat
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A Model of Phosphofructokinase and Glycolytic Oscillations in the Pancreatic Beta-cell
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Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, II Model Studies
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Evolution of Immunological Memory and the Regulation of Competition between Pathogens
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Infection dynamics in HIV-specific CD4 T cells: Does a CD4 T cell boost benefit the host or the virus?
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A dynamical perspective of CTL cross-priming and regulation: implications for cancer immunology
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Specific therapy regimes could lead to long-term immunological control of HIV
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Dynamics of killer T cell inflation in viral infections
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Transduction of Intracellular and Intercellular Dynamics in Yeast Glycolytic Oscillations
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Mathematical analysis of a mechanism for autonomous metabolic oscillations in continuous culture of Saccharomyces cerevisae
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Oxidative ATP Synthesis in Skeletal Muscle is Controlled by Substrate Feedback
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Computer Modeling of Mitochondrial Tricarboxylic Acid Cycle, Oxidative Phosphorylation, Metabolite Transport, and Electrophysiology
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Constancy and variability of contractile efficiency as a function of calcium and cross-bridge kinetics: simulation
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The myogenic response in isolated rat cerebrovascular arteries: smooth muscle cell model
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Population-Based Analysis of Methadone Distribution and Metabolism Using an Age-Dependent Physiologically Based Pharmacokinetic Model
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Crossbridge Model Compatible with the Linear Relationship between Left Ventricular Oxygen Consumption and Pressure-Volume Area
Yates, Stark, Klein, Antia, Callard, 2007
Understanding the slow depletion of memory CD4+ T cells in HIV infection
Yi, Fogelson, Keener, Peskin, 2003
A Mathematical Study of Volume Shifts and Ionic Concentration Changes during Ischemia and Hypoxia
Youm, Kim, Han, Kim, Joo, Leem, Goto, Noma, Earm, 2006
A mathematical model of pacemaker activity recorded from mouse small intestine
Zager, Schlosser, Tran, 2007
A delayed nonlinear PBPK model for genistein dosimetry in rats
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Two Components of the Delayed Rectifier K+ Current in Ventricular Myocytes of the Guinea Pig Type
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Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node.